• Earthquakes and Structures
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• v.24 no.1
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• pp.11-20
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• 2023

"Performance-based design (PBD)" is based on designing a structure with choosing a performance target under design criteria to increase the structure's resistance against earthquake effect. The plastic hinge formation is determined as one of the fundamental data in finite elements nonlinear analysis to distinguish the condition of the structure where more significant potential damage could occur. If the number of plastic hinges in the structure is increased, the total horizontal load capability of the structure is increased, also. Theoretically, when the number of plastic hinges of the plane frame structure reaches "the degree of hyperstaticity plus one", the structure will reach the capability of the largest ultimate horizontal load. As the number of plastic hinges to be formed in the structure increases towards the theoretical plastic hinge number (TPHN), the total horizontal load capability of the structure increases, proportionally. In the previous studies of the authors, the features of examining the new performance criteria were revealed and it was formulated as follows "Increase the total number of plastic hinges to be formed in the structure to the number of theoretical plastic hinges as much as possible and keep the structure below its targeted performance with related codes". With this new performance criterion, it has been shown that the total lateral load capability of the building is higher than the total lateral load capability obtained with the traditional PBD method by the FEMA 440 and FEMA 356 design guides. In this study, PBD analysis results of structures with frame carrier systems are presented in the light of the Turkey Building Earthquake Code 2019. As a result of this study, it has been shown that the load capability of the structure in the examples of structures with frame carrier system increases by using this new performance criterion presented, compared to the results of the examination with the traditional PBD method in TBEC 2019.

• Korean Journal of Acupuncture
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• v.39 no.4
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• pp.132-141
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• 2022

Objectives : Some acupoints are commonly utilized to treat a variety of diseases. The acupoints appear to have a wide range of effects caused by several mechanisms. The purpose of this study is to investigate into the potential role of microRNAs (miRNAs) in the multipotent effects of individual acupoint stimulation. Methods : We examined the miRNA expressions in the dorsal root ganglia (DRG) of neuropathic or inflammatory pain rats following ST36 and GB34 electroacupuncture (EA) stimulation. Neuropathic pain was induced by L5 spinal nerve ligation. Inflammatory pain was induced by knee joint injection of Complete Freund's adjuvant (CFA). EA was given under gaseous anesthesia with the same parameters (1mA, 2Hz, 30 min) in 5 consecutive days. Pain behaviors and miRNA expressions were analyzed. Results : In rats with neuropathic and inflammatory pain, EA treatments significantly enhanced the paw withdrawal threshold and weight-bearing force. After nerve injury, 36 miRNAs were upregulated in the DRG of neuropathic rats, while EA downregulated 10 of them. Furthermore, 14 miRNAs were downregulated following nerve damage, while one was increased by EA. 15 miRNAs were increased in the DRG of inflammatory rats following CFA injection, while 5 were downregulated by EA. Furthermore, 17 miRNAs were downregulated following CFA injection, while 7 were increased by EA. The miRNAs rno-miR-335, rno-miR-381-5p, rno-miR-1306-3p, and rno-miR-1839-3p were regulated by EA in both models. Conclusions : In two pain models, EA applied to ST36 and GB34 regulated miRNA expression differently. There appeared to be both acupoint-specific and non-specific miRNAs, and miRNA regulation of differential protein expression may modulate a variety of EA mechanisms.

• Composites Research
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• v.36 no.4
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• pp.259-263
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• 2023

This study investigated the open hole tensile (OHT) properties of carbon fiber/epoxy composites and compared them to bolt joint tensile (BJT) properties. The net nominal modulus and strength (1376 MPa) were found to be higher than the gross nominal strength (1041 MPa), likely due to increasing hole size. The OHT and BJT specimens exhibited similar stiffness, as expected without bolt rotation causing secondary bending. OHT specimens experienced a sharp drop in stress indicating unstable crack propagation, delamination, and catastrophic failure. BJT specimens failed through shear out on the bolt side and bearing failure on the nut side, involving fiber kinking, matrix splitting, and delamination, resulting in lower strength compared to OHT specimens. The strength retention of carbon fiber/epoxy composites with open holes was 66%. Delamination initiation at the hole's edge caused a reduction in the stress concentration factor. Filling the hole with a bolt suppressed this relieving mechanism, leading to lower strength in BJT specimens compared to OHT specimens. Bolt joint efficiency was calculated as 15%. The reduction in strength in bolted joints was attributed to fiber-matrix splitting and delamination, aligning with Hart Smith's bolted joint efficiency diagram. These findings contribute to materials selection and structural reliability estimation for carbon fiber/epoxy composites. They highlight the behavior of open hole and bolt joint configurations under tensile loading, providing valuable insights for engineering applications.

• Smart Structures and Systems
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• v.32 no.1
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• pp.23-35
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• 2023

Steel bolted joint is an important part of steel structure, and its damage directly affects the bearing capacity and durability of steel structure. Currently, the existing research mainly focuses on the identification of corroded bolts and corroded bolts respectively, and there are few studies on multiple states. A detection framework of corroded and loosened bolts is proposed in this study, and the innovations can be summarized as follows: (i) Vision Transformer (ViT) is introduced to replace the third and fourth C3 module of you-only-look-once version 5s (YOLOv5s) algorithm, which increases the attention weights of feature channels and the feature extraction capability. (ii) Three states of the steel bolts are considered, including corroded bolt, bolt missing and clean bolt. (iii) Line segment detector (LSD) is introduced for bolt rotation angle calculation, which realizes bolt looseness detection. The improved YOLOv5s model was validated on the dataset, and the mean average precision (mAP) was increased from 0.902 to 0.952. In terms of a lab-scale joint, the performance of the LSD algorithm and the Hough transform was compared from different perspective angles. The error value of bolt loosening angle of the LSD algorithm is controlled within 1.09%, less than 8.91% of the Hough transform. Furthermore, the proposed framework was applied to fullscale joints of a steel bridge in China. Synthetic images of loosened bolts were successfully identified and the multiple states were well detected. Therefore, the proposed framework can be alternative of monitoring steel bolted joints for management department.

• Plant Biotechnology Reports
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• v.1 no.1
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• pp.19-25
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• 2007

To develop an efficient screening method for detection of the transgene in Chinese cabbage (Brassica rapa spp. pekinensis) utilizing Basta spray, optimal conditions for Basta application were examined in this study. Two transgenic Chinese cabbage lines were obtained through Agrobacterium-mediated transformation and used as transgenic positive controls in the Basta screening experiment. Differential concentrations of glufosinate-ammonium were sprayed into three different growth stages of 12 commercial Chinese cabbage cultivars. The results showed that no plants could survive higher than 0.05% glufosinate-ammonium, and plants at the 2-3 leaf stage were most vulnerable to glufosinate-ammonium. On the other hand, no damage was observed in the transgenic control plants. Reliability of the Basta spray method was proven by showing perfect co-segregation of the tolerance to glufosinate-ammonium and the presence of the bar gene in T₁ segregating populations of the transgenic lines, as revealed by both PCR and Southern blot analyses. Using the developed Basta screening method, we tried to investigate the transgene flow through pollen dispersal, but failed to detect any transgene-containing non-transgenic Chinese cabbages whose parents had been planted adjacent to transgenic Chinese cabbages in field conditions. However, the transgene was successfully detected using Basta spray from the non-transgenic plants bearing the transgene introduced by hand-pollination. Since the Basta spray method developed in this study is easy to apply and economical, it will be a valuable tool for understanding the mechanism of gene flow through pollen transfer and for establishing a biosafety test protocol for genetically modified (GM) Chinese cabbage cultivars.

• Earthquakes and Structures
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• v.23 no.3
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• pp.271-282
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• 2022

Seismic resisting self-centering bridge piers with high energy dissipation and negligible residual displacement after an earthquake event are focus topics of current structural engineering. The energy dissipation components of typical bridge piers are often relatively single; and exhibit a certain level of damage under earthquakes, leading to large residual displacements and low cumulative energy dissipation. In this paper, a novel socket self-centering bridge pier with a hybrid energy dissipation system is proposed. The seismic resilience of bridge piers can be improved through the rational design of annular grooves and rubber cushions. The seismic response was evaluated through the finite element method. The effects of rubber cushion thickness, annular groove depth, axial compression ratio, and lateral strength contribution ratio of rubber cushion on the seismic behavior of bridge piers are systematically studied. The results show that the annular groove depth has the greatest influence on the seismic performance of the bridge pier. Especially, the lateral strength contribution ratio of the rubber cushion mainly depends on the depth of the annular groove. The axial compression ratio has a significant effect on the ultimate bearing capacity. Finally, the seismic design method is proposed according to the influence of the above research parameters on the seismic performance of bridge piers, and the method is validated by an example. It is suggested that the range of lateral strength contribution ratio of rubber cushion is 0.028 ~ 0.053.

• Computers and Concrete
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• v.33 no.3
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• pp.251-264
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• 2024

The present study pertains to the effects of variations in the location and size of drilled web openings on the behavior of fixed-fixed reinforced concrete (RC) beams. For this purpose, a reference bending beam with a transverse opening in each half span was tested to failure. Later, the same beam was modeled and analyzed with the help of finite element software using ABAQUS. Upon achieving close agreement between the experimental and numerical results, the location and size of the web opening were altered to uncover the effects of these factors on the shear strength and load-deflection behavior of RC beams. The experimental failure mode of the tested beam and the numerical results were also verified by theoretical calculations. In numerical analysis, when compared to the reference (D0) specimen, if the distance of the opening center from the support is 0 or h or 2h, reduction in load-bearing capacity of 1.5%-22.8% or 2.0%-11.3% or is 4.1%-40.7%. In other words, both the numerical analyses and theoretical calculations indicated that the beam behavior shifted from shear-controlled to flexure-controlled as the openings approached the supports. Furthermore, the deformation capacities, energy absorption values, and the ductilities of the beams with different opening diameters also increased with the decreasing distance of the opening from supports. Web compression failure was shown to be the predominant mode of failure of beams with large diameters due to the lack of sufficient material in the diagonal compression strut of the beam. The present study indicated that transverse openings with diameters, not exceeding about 1/3 of the entire beam depth, do not cause the premature shear failure of RC beams. Finally, shear damage should be prevented by placing special reinforcements in the areas where such gaps are opened.

• Computers and Concrete
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• v.33 no.4
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• pp.399-407
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• 2024

This study nondestructively examined the evolution of crack density in ultra-high performance concrete (UHPC) upon cyclic loading. Uniaxial compression was repeatedly applied to the cylindrical specimens at levels corresponding to 32% and 53% of the maximum load-bearing capacity, each at a steady strain rate. At each stage, both P-wave and S-wave velocities were measured in the absence of the applied load. In particular, the continuous monitoring of P-wave velocity from the first loading prior to the second loading allowed real-time observation of the strengthening effect during loading and the recovery effect afterwards. Increasing the number of cycles resulted in the reduction of both elastic wave velocities and Young's modulus, along with a slight rise in Poisson's ratio in both tested cases. The computed crack density showed a monotonically increasing trend with repeated loading, more significant at 53% than at 32% loading. Furthermore, the spatial distribution of the crack density along the height was achieved, validating the directional dependency of microcracking development. This study demonstrated the capability of the crack density to capture the evolution of microcracks in UHPC under cyclic loading condition, as an early-stage damage indicator.

• The Korean Journal of Archival Studies
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• no.16
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• pp.303-339
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• 2007

"The damage incurred from forced mobilization under the Japanese Imperialism" means the life, physical, and property damage suffered by those who were forced to lead a life as soldiers, civilians attached to the military, laborers, and comfort women forcibly mobilized by the Japanese Imperialists during the period between the Manchurian Incident and the Pacific War. Up to the present time, every effort to restore the history on such a compulsory mobilization-borne damage has been made by the damaged parties, bereaved families, civil organizations, and academic circles concerned; as a result, on March 5, 2004, Disclosure act of Forced Mobilization under the Japanese Imperialism[part of it was partially revised on May 17, 2007]was officially established and proclaimed. On the basis of this law, the Truth Commission on Forced Mobilization under the Japanese Imperialism Republic of Korea[Compulsory Mobilization Commission hence after] was launched under the jurisdiction of the Prime Minister on November 10, 2004. Since February 1, 2005, this organ has begun its work with the aim of looking into the real aspects of damage incurred from compulsory mobilization under the Japanese Imperialism, by which making the historical truth open to the world. The major business of this organ is to receive the damage report and investigation of the reported damage[examination of the alleged victims and bereaved families, and decision-making], receipt of the application for the fact-finding & fact finding; fact finding and matters impossible to make judgment; correction of a family register subsequent to the damage judgement; collection & analysis of data concerning compulsory mobilization at home and from abroad and writing up of a report; exhumation of the remains, remains saving, their repatriation, and building project for historical records hall and museum & memorial place, etc. The Truth Commission on Compulsory Mobilization has dug out and collected a variety of records to meet the examination of the damage and fact finding business. As is often the case with other history of damage, the records which had already been made open to the public or have been newly dug out usually have their limits to ascertaining of the diverse historical context involved in compulsory mobilization in their quantity or quality. Of course, there may happen a case where the interested parties' story can fill the vacancy of records or has its foundational value more than its related record itself. The Truth Commission on Compulsory mobilization generated a variety of oral history records through oral interviews with the alleged damage-suffered survivors and puts those data to use for examination business, attempting to make use of those data for public use while managing those on a systematic method. The Truth Commission on compulsory mobilization-possessed oral history archives were generated based on a drastic planning from the beginning of their generation, and induced digital medium-based production of those data while bearing the conveniences of their management and usage in mind from the stage of production. In addition, in order to surpass the limits of the oral history archives produced in the process of the investigating process, this organ conducted several special training sessions for the interviewees and let the interviewees leave their real context in time of their oral testimony in an interview journal. The Truth Commission on compulsory mobilization isn't equipped with an extra records management system for the management of the collected archives. The digital archives are generated through the management system of the real aspects of damage and electronic approval system, and they plays a role in registering and searching the produced, collected, and contributed records. The oral history archives are registered at the digital archive and preserved together with real records. The collected oral history archives are technically classified at the same time of their registration and given a proper number for registration, classification, and keeping. The Truth Commission on compulsory mobilization has continued its publication of oral history archives collection for the positive use of them and is also planning on producing an image-based matters. The oral history archives collected by this organ are produced, managed and used in as positive a way as possible surpassing the limits produced in the process of investigation business and budgetary deficits as well as the absence of records management system, etc. as the form of time-limit structure. The accumulated oral history archives, if a historical records hall and museum should be built as regulated in Disclosure act of forced mobilization, would be more systematically managed and used for the public users.

• Radiation Oncology Journal
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• v.20 no.3
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• pp.253-263
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• 2002

Purpose : In order to understand in vivo radiation damage modifying of bFGF on jejunal mucosa, bone marrow and the effect of bFGF on the growth of transplanted mouse sarcoma 180 tumor in mice. Materials and Methods : Mice were treated with $6\;{\mu}g$ of bFGF at 24 hours and 4 hours before exposing to 600 cGy, 800 cGy and 1,000 cGy total body irradiation (TBI), and then exposed to 3,000 cGy local radiation therapy on the tumor bearing thigh. Survival and tumor growth curve were plotted in radiation alone group and combined group of bFGF and irradiation (RT). Histologic examination was performed in another experimental group. Experimental groups consisted of normal control, tumor control, RT (radiation therapy) alone, $6\;{\mu}g$ bFGF alone, combined group of $3\;{\mu}g$ bFGF and irradiation (RT), combined group of $6\;{\mu}g$ bFGF and irradiation (RT). Histologic examination was peformed with H-E staining in marrow, jejunal mucosa, lung and sarcoma 180 bearing tumor. Radiation induced apoptosis was determined in each group with the DNA terminal transferase nick-end labeling method ($ApopTag^{\circledR}$ S7100-kit, Intergen Co.) Results : The results were as follows 1) $6\;{\mu}g$ bFGF given before TBI significantly improved the survival of lethally irradiated mice. bFGF would protect against lethal bone marrow syndrome. 2) $6\;{\mu}g$ bFGF treated group showed a significant higher crypt depth and microvilli length than RT alone group (p<0.05). 3) The bone marrow of bFGF treated group showed less hypocellularity than radiation alone group on day 7 and 14 after TBI (p<0.05), and this protective effect was more evident in $6\;{\mu}g$ bFGF treated group than that of $3\;{\mu}g$ bFGF treated group. 4) bFGF protected against early radiation induced apoptosis in intestinal crypt cell but might have had no antiapoptotic effect in bone marrow stem cell and pulmonary endothelial cells. 5) There was no significant differences in tumor growth rate between tumor control and bFGF alone groups (p>0.05). 6) There were no significant differences in histopathologic findings of lung and mouse sarcoma 180 tumor between radiation alone group and bFGF treated group. Conclusions : Our results suggest that bFGF protects small bowel and bone marrow from acute radiation damage without promoting the inoculated tumor growth in C3H mice. Improved recovery of early responding normal tissue and reduced number of radiation induced apoptosis may be possible mechanism of radioprotective effect of bFGF.