• Journal of Korean Neurosurgical Society
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• v.30 no.9
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• pp.1059-1064
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• 2001

Objective : 6R-Tetrahydrobiopterin(BH4) is a cofactor for the aromatic amino acid hydroxylases which is essential for the biosynthesis of catecholamines and serotonin. It also acts as a cofactor for nitric oxide synthase, and stimulates the release of some neurotransmitters such as dopamine, serotonin, acetylcholine and glutamate. Recently, it has been reported that BH4 could induce cellular proliferation and enhance neuronal survival. This study was performed to investigate the antioxidative effect of BH4 on the various oxidative insults in mouse cerebral cortical cell cultures. Methods : Iron ion(FeCl2), zinc ion(ZnCl2), sodium nitroprusside(SNP) and buthionine sulfoximine(BSO, a glutathione depletor) were used as oxidants. Cell death was assessed by measurement of lactate dehydrogenase efflux to bathing media at the end of exposure. Result : All 4 oxidants induced neuronal cell death associated with cell body swelling, which was markedly inhibited by trolox($100{\mu}M$), a vitamin E analog. BH4($10-100{\mu}M$) markedly inhibited the neuronal cell death induced by all 4 oxidants($20{\mu}M\;Cu^{2+}$, $20{\mu}M\;Zn^{2+}$, $1{\mu}M$ SNP or 1mM BSO). However, BH4 failed to inhibit the neuronal cell death induced by 24hr exposure to $20{\mu}M$ NMDA. Conculsion : These results suggest that BH4 has antioxidative action independently of any actions of enzyme cofactor.

• Land and Housing Review
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• v.2 no.3
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• pp.269-276
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• 2011

Recently, the chance of dew condensation in apartment buildings is increasing because of several reasons. For example, ventilation rate has been decreased because of high-insulations and airtightness for saving energy. Besides, the humidity has been made by drying washes, cooking and bathing inside of apartment buildings. However, there is lack of resonable design criteria for preventing condensation in real life and real surroundings. Therefore, this study is aimed at making a resonable design criteria of preventing condensation by measuring the indoor temperature and humidity in real life. In addition to this, it is aimed at making a resonable outdoor condition and classifying regions by using weather data. The following are the results. The interior criterion for condensation was set up $25^{\circ}C$ and a relative humidity of 55%. The outdoor criterion for condensation was set up $20^{\circ}C$, $-15^{\circ}C$, and $10^{\circ}C$ respectively for the hard frost, middle, and southern areas.

• Smart Media Journal
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• v.5 no.4
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• pp.131-137
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• 2016

Since the phenomenon that the consumers slip important calls since they do not know the receiving information of the smart phone in spaces which smart phones can not be carried, the development of technology to solve this problem is urgent and the cases of burglary and losses of smart phones during hobby and recreation life are increasing and especially since burglary behaviors are occurring much in places such as bathing resort, swimming pool, Korean dry sauna, sauna and spa etc, the schemes to protect smart phones during hobbies and recreation life is needed. Since the smart watch, the conventional wearable device are high price machines and due to the burden about A/S costs for the damage or failure of the machine during exercise, hobbies and recreation activities, the burden about the use is high, development of products which can reduce such burden and emphasize the usefulness is urgent and in order to solve this problem, the added value and psychological repercussion effect will be very high in areas of smart phone users and utilizing them by developing the system which can know if the smart phone has received calls at least in places where smart phones can not be carried.

• Journal of Veterinary Clinics
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• v.30 no.4
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• pp.283-287
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• 2013

Canine skin is a highly dynamic organ that is constantly adapted to changes in its environment. It provides structural, sensory, immunologic, and physiologic functions and contributes an essential barrier function against potential environmental insults. We assessed the changes of canine skin hydration, pH, and protein contents by noninvasive method according to the frequency of application with canine commercial shampoo. Canine commercial shampoo was applied topically every other day, 5 days, and 8 days on different sites, respectively in 8 dogs. Saline-applied site was as a control. Skin hydration was increased and skin surface pH was decreased significantly in canine commercial shampoo-applied site every other day (p < 0.05). Also, skin protein concentration measured by D-squame$^{(R)}$ tape stripping method was increased significantly in canine commercial shampoo-applied site every other day (p < 0.05). There were alterations on every 5 days and 8 days, but not significantly. These results may be recognized that the frequent use of canine commercial shampoo cause abnormalities of the skin barrier function and alteration of stratum corneum integrity/cohesion. Consequently it was suggested that bathing the dog with canine commercial shampoo was appropriate every 5 or 8 days.

• Journal of Korean Physical Therapy Science
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• v.10 no.1
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• pp.30-37
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• 2003

Purpose : The purpose of this study is giving the healthy promotion and it's related data base for out-patients who had stroke via evaluating the general characters of their active daily living and physical therapy Method : This study researched 81 patients who had received physical therapy service in 6 general hospitals located Pusan city responded to the self-assessment questionnaires from July 2002 to August 2002. Conclusion : In this study, patients were composed of 61.7% of male, 65.4% of 50's-60's in the age, 56.8% of cerebral infarction, and 60.5% of right hemiplegia. 74.1% of patients received physical therapy after 6 months from an attack, only 62.9% used orthosis & gait aids, and 59.2% received medical care 2 or 3 times per week. 40.7% of patients had over 9 hours sleeping time and 22% had reduced $1{\sim}2hours$ before hospitalization. 90% did not have drinking and smoking. 91.4% had 3 times eating per day, and 67.7% did not have good nutrition. The reasons of that were their eating habit, 542% of eating-giver, 3.7% of economic problem. 46.9% of patients used healthy food. In active daily living, patients can't do drinking by cup, voiding & defication by themselves, however patients can't do wearing/take off, etiquette for dressing, bathing, stepping by themselves. 40.7% of patients don't wear orthosis, 55.6% of patients don't use W/C. Part of physical therapy that patients concerned importantly exercise for prevention of joint distortion, management of affected side, and 80% of patients was also concerned other's part, significantly. 71.8% of patients & care-givers want to receive physical therapy at home, and 74% of patients do physical therapy by themselves at home along teached hospitalization.

• Journal of the Korean Home Economics Association
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• v.44 no.7 s.221
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• pp.177-188
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• 2006

This study evaluated 26 elderly residents living independently in 4 group homes for their abilities in daily living and analyzed their behaviors of space occupancy and activities of daily living. The aim of the study was to identify the relationships between the physical environments of the group homes and the daily activities of the residents. The results of this study are summarized as follows. 1) Most residents in the group home considered bathing and cooking to be the most difficult of their living activities. The residents were categorized into "Independent," "Semi-dependent" and "Dependent" groups, on the basis of their ADL and IADL scores, and individual groups were examined. On ADL scorelt was shown, then, that 65.4% of the residents were was independent in ADL, but there was no any significant difference in IADL between the independent, semi-dependent and dependent groups. In addition, there was a difference in ADL and IADL among the groups. The independent group's residents were shown to be independent in ADL and IADL, whereas the but those of the semi-dependent and dependent groups' residents were lower in IADL than in ADL. 2) When their behaviors of space occupancy were examined, it appeared that the independent group showed a different space sharing pattern among individual residents, with a wide range of behavior of space occupancy. Meanwhile, The semi-dependent group mostly shared a common space with simple activities of daily living while no any service low leisure program was provided. However, the dependent group mainly consisted of residents who had a low level of independence in ADL and IADL, so that their behaviors of space occupancy were entirely negative.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.14 no.1
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• pp.66-76
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• 2008

Purpose : The purpose of the study was to determine Effects of the ADL Group Study Program Training on Functional Independence and Quality of Life for the CNS Patients. Methods : Thirty patients with stroke were assigned to experimental and control group. During eight weeks, both group participated in the conventional physical therapy and only the experimental group added in the ADL Group Study program. Experimental group performed two a week for 8 weeks and both group were scored Mini-Mental State Examination-Korean version before the training. The data were analyzed with frequency, independent t-test, paired t-test using SPSS PC(ver.12.0). Results : The result of this study is as fallows : First, after eight weeks, the experimental group the significant improvement in Korean Activity Daily Living scale, washing(p<0.01), bathing, ambulation, toilet using(p<0.05) and decorating, the short distance transfer(p<0.05) in Korean Independent Daily Living scale, vitality(p<0.05) in Quality of Life score. Conclusion : These finding suggest that the ADL Group Study Program Training can be used to improve functional independent and quality of life for the CNS patients. Also, the result of this study can provide a reference for the successful therapeutic program in CNS patients.

• The Journal of Pediatrics of Korean Medicine
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• v.15 no.1
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• pp.235-253
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• 2001

Tae-yeul is the baby's disorder inheritted by its mother during fregnancy. This is due to its mother's overeating hot, fatty food and taking harmful medicine. So internal physical fever is accumulated in mother's body, and it heats up the placenta and the umbilical cord. Generally, this disorder means the skin disease that is occurred from $2{\sim}5$ months to 1 year after birth. It is specialized by the dirty oozing, a severe itching and the rash at its head and face. It is similar in its symptoms such as atopic dermatitis in western medicine. Recently, this disease has the increasing tendency of prevalence rate because of the bad atmosphere and the invironmental pollution. The results were summerised as follows; 1, 2, 3, 4 1. The causes of Tae-yeul are summarized by fragnat woman's contacting a cool air, overating a hot and toxic food and taking emotional shock. 2. The symptoms of Tae-yeul are the edema on upper eyelids, stifling convulsions, flush, the fever of one side body, the asthma of sputum increase, the yawing of the tired mind, the bowl complaint, the red urine and urination disturbance. 3. In the treatment method of Tae-yeul, its mother feed her milk after taking a madicine. So one must expect to be treated slowly. If one tries to treat it with a cool madicine quickly, it can cause vomitting or a serious disorder. 4. In the prescription of Tae-yeul, they used a Moktongsan, a Chiwhnagtang, an Yangyoubang, a Tojuksan, a Whangyunsan, a Juryungtang and a Kamdutang, etc.. For the method of cleaning face or bathing, they used Sasungsan, Whanbaekpijuntang. 5. Tae-yeul including Naesun, Taelyumchang, yousun, etc. is similar to the atopic dermatitis of western medicine in its symptoms.

• Physical Therapy Korea
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• v.14 no.1
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• pp.64-73
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• 2007

The purpose of this study was to find any correlations among Postural Assessment Scale for Stroke (PASS), Modified Barthel Index (MBI), Tone Assessment Scale (TAS), Motor Assessment Scale-Gait (MAS-G), Fugl Meyer-Balance (FM-B), and to predict MBI from subscales of the PASS. The subjects were 41 stroke patients of the Korea National Rehabilitation Center in Seoul. The main outcome measures were postural control (PASS), gait (MAS-G), Balance (FM-B), Tone (TAS), ADL (MBI). The data was analyzed using the Pearson product correlation. PASS scale was used between other clinical and instrumental indexes, multiple stepwise regression analyses were performed to identify prognostic factors for ADL incline, and Cronbach's alpha coefficient was used to identify internal consistency on PASS scale. The results of this study areas follows: 1. The highest level was sitting without support, the lowest level was standing on paretic leg on PASS scale. The highest level was chair/bed transfer, the lowest level was bathing on MBI. 2. All items of the PASS, except postural tone were significantly correlated with Gait, Balance, MBI (p<.01), 3. The Internal Consistency (Cronbach's alpha coefficient=.85) was very high, indicating that the PASS is homogeneous and is likely to produce consistent response. Furthermore, the sums of maintaining position items and of changing-position items were strongly correlated (r=.64, p<.05) and there were significant correlations between sums of PASS, sums of maintaining position items (r=.87, p<.01), and changing-position items (r=.93, p<.01). 4. The standing without support of the PASS items was the strongest variance ($R^2$=.85) of the predicting ADL function. These findings provide strong evidence of the predictive value of the postural control on gait, Balance, ADL function in stroke patients and to can provide a reference for the successful therapeutic program and more improved functional recovery.

• YAKHAK HOEJI
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• v.55 no.3
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• pp.247-250
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• 2011

An increase in ventricular pressure can alter cardiac excitation and contraction. Recent report has demonstrated that fluid pressure (FP) suppresses L-type $Ca^{2+}$ current with acceleration of the current inactivation in ventricular myocytes. Since the L-type $Ca^{2+}$ channels known to be regulated by intracellular pH ($pH_i$), this study was designed to explore whether pressurized fluid flow affects pHi in isolated rat ventricular myocytes. A flow of pressurized (~16 dyne/$cm^2$) fluid, identical to that bathing the myocytes, was applied onto single myocytes, and intracellular $H^+$ concentration was monitored using confocal $H^+$ imaging. FP significantly decreased $pH_i$ by $0.07{\pm}0.01$ pH units (n=16, P<0.01). Intracellular acidosis enhances the activity of $Na^+-H^+$ exchanger (NHE). Therefore, we examined if the NHE activity is increased by FP using the NHE inhibitor, HOE642. Although HOE642 did not alter $pH_i$ in control conditions, it decreased $pH_i$ in cells pre-exposed to FP, suggesting enhancement of NHE activity by FP. In addition, FP-induced intracellular acidosis was larger in cells pre-treated with HOE642 than in cells under the control conditions. These results suggest that FP induces intracellular acidosis and that NHE may contribute to extrude $H^+$ during the FP-induced acidosis in rat ventricular myocytes.