• Title/Summary/Keyword: Basic and Analytical Science

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AN INNOVATION DIFFUSION MODEL IN PARTIAL COMPETITIVE AND COOPERATIVE MARKET: ANALYSIS WITH TWO INNOVATIONS

  • CHUGH, S.;GUHA, R.K.;DHAR, JOYDIP
    • Journal of Applied and Pure Mathematics
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    • v.4 no.1_2
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    • pp.27-36
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    • 2022
  • An innovation diffusion model is proposed model consists of three classes, namely, a non-adopter class, adopter class innovation-I, and adopter class innovation-II in a partially competitive and cooperative market. The proposed model is analyzed with the help of the qualitative theory of a system of ordinary differential equations. Basic influence numbers associated with first and second innovation $R_{0_1}$ and $R_{0_2}$ respectively in the absence of each other are quantified. Then the overall basic influence number (R0) of the system is assessed for analyzing stability in the market in different situations. Sensitivity analysis of basic influence numbers associated with first and second innovation in the absence of each other is carried out. Numerical simulation supports our analytical findings.

Network-Based Protein Biomarker Discovery Platforms

  • Kim, Minhyung;Hwang, Daehee
    • Genomics & Informatics
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    • v.14 no.1
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    • pp.2-11
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    • 2016
  • The advances in mass spectrometry-based proteomics technologies have enabled the generation of global proteome data from tissue or body fluid samples collected from a broad spectrum of human diseases. Comparative proteomic analysis of global proteome data identifies and prioritizes the proteins showing altered abundances, called differentially expressed proteins (DEPs), in disease samples, compared to control samples. Protein biomarker candidates that can serve as indicators of disease states are then selected as key molecules among these proteins. Recently, it has been addressed that cellular pathways can provide better indications of disease states than individual molecules and also network analysis of the DEPs enables effective identification of cellular pathways altered in disease conditions and key molecules representing the altered cellular pathways. Accordingly, a number of network-based approaches to identify disease-related pathways and representative molecules of such pathways have been developed. In this review, we summarize analytical platforms for network-based protein biomarker discovery and key components in the platforms.

A Review on the Analytical Techniques for the Determination of Fluorine Contents in Soil and Solid Phase Samples (토양 및 고체시료 중 불소함량 측정기법)

  • An, Jinsung;Kim, Joo-Ae;Yoon, Hye-On
    • Journal of Soil and Groundwater Environment
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    • v.18 no.1
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    • pp.112-122
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    • 2013
  • Current status of soil contamination with fluorine and its source were investigated. The basic principles and procedures of various techniques for the analysis of fluorine contents in soil and solid phase samples were summarized in this review. Analysis of fluorine in solid matrices can be achieved by two types of techniques: (i) UV/Vis spectrophotometer or ion selective electrode (ISE) analysis after performing appropriate extraction steps and (ii) direct solid analysis. As the former cases, the standard method of Korean ministry of environment, alkali fusion-ISE method, pyrohydrolysis, oxygen bomb combustion, aqua regia digestion-automatic analysis, and sequential extraction-ISE method were introduced. In addition, direct analysis methods (i.e., X-ray fluorescence spectrometry and proton induced gamma-ray emission spectrometry) and atomic spectrometry combining with the equipment for introducing solid phase sample were also reviewed. Fluorine analysis techniques can be reasonably selected through site-specific information such as matrix condition, contamination level, the amount of samples and the principles of various methods for the analysis of fluorine presented in this review.

암석 용해방법에 따른 미량원소 분석결과 비교

  • 최만식;정창식;박계헌
    • The Journal of the Petrological Society of Korea
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    • v.3 no.1
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    • pp.41-48
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    • 1994
  • Three USGS rock standards (G-2, W-2, and BHVO-1) are decomposed by three different methods, such as open beaker, microwave oven, and alkali fusion method, to compare the effect of decomposition methods for trace elememt analysis in the rock samples. Solubilized trace elements are measured with inductively coupled plasma mass spectrometer (ICP-MS). Generally the analytical results of trace elements between open beaker and microwave digestion method are not different. In case of alkali fusion method, some volatile elements such as Pb, Cu, and Rb are considerably lost. Using acid digestion method, Zr and Hf concentrations are lowered in case that these elements are concentrated in refractory minerals. The concentrations of rare earth elements are generally consistent with the recommended values, but due to large dilution factor, there are some analytical problems in alkali fusion method.

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Structural Analysis of Petroleum Fractions by Near-Infrared and $^{13}C$-NMR Spectroscopy (근적외선과 $^{13}C$-핵자기 공명 분광학에 의한 석유유분 구조분석)

  • Choi, Ju-Hwan;Kim, Hai-Dong;Choi, Young-Sang
    • Analytical Science and Technology
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    • v.9 no.2
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    • pp.168-178
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    • 1996
  • Molecular structures of petroleum fractions(diesel fuel, bunker-C oil, lubricant base stocks) have been analyzed and compared in terms of the compositions (aromatics, naphtherucs, paraffinics), aromatics(benzene-nuclear and bonded alkyl groups), C2(methylene) carbon atoms % $C_{\alpha}$ and $C_{\beta}$ carbon stom % in alkyl groups and paraffins(branched and normal) by near-infrared and $^{13}C$-NMR spectroscopy.

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First GC-IRMS in Korea and Its Application Fields (국내 최초로 도입된 GC-IRMS와 응용분야 소개)

  • Shin, Woo-Jin;Lee, Kwang-Sik;Ko, Kyung-Seok
    • Economic and Environmental Geology
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    • v.40 no.5
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    • pp.699-703
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    • 2007
  • Compound-specific isotope analysis (CSIA) by isotope ratio mass spectrometer (IRMS) interfaced with gas chromatography (GC) is a state of the art analytical technique for stable isotopes in earth sciences, environmental sciences and forensics. Since early 1990s, GC-IRMS has been widely used to investigate the authenticity of food in forensic science and to trace the sources of organic contaminants in environmental science. In Korea, a GC-IRMS was firstly installed at the Korea Basic Science Institute (KBSI) in early 2005. In this study, we introduce the GC-IRMS of the KBSI shortly to stimulate various isotope-related researches of Korea, and report preliminary CSIA results for BTEX of different manufacturers.

Response Mechanism of 5, 10, 15, 20-tetraphenyl(porphyrinato) Manganase(III) chloride-Based Ion-Selective Membranes (망간포르피린을 함유한 고분자형 이온선택성 막전극의 감응 메카니즘)

  • Hong, Young Ki;Kang, You Ra;Shin, Dae Ho;Shin, Doo Soon;Cha, Geun Sig;Nam, Hakhyun
    • Analytical Science and Technology
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    • v.9 no.3
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    • pp.270-278
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    • 1996
  • Response mechanism for the chloride-selective membrane doped with 5, 10, 15, 20-tetraphenyl(porphyrinato)manganase(III) chloride(Mn(TPP)Cl) in PVC/DOS matrix is proposed by examining the visible spectra of the corresponding optode membrane. The visible spectra of Mn(TPP)Cl-doped membrane placed in aqueous solution show that the chloride ligand is easily replaced with water molecule. When other halogen ions, such as $F^-$, $Br^-$ and $I^-$, are added to the sample solution, they replace the water ligand, exhibiting distinctive change in the Soret band of Mn(TPP). On the other hand, bulky anions, such as SCN and salicylate, do not form a bond with the central metal. These results suggests that the potentiometric response of Mn(TPP)-based membrane results either from the ligand exchange (water with halides) at the central metal or from the counter ion exchange (chlorides with bulky lipophilic anions) around the positively charged porphyrin molecule in membrane phase. It was also noted that both hydration enthalpies of anions and their binding constants to Mn(TPP) play critical role in determining the potentiometric selectivity pattern of the membrane.

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A novel analytical approach for advection diffusion equation for radionuclide release from an area source

  • Esmail, S.;Agrawal, P.;Aly, Shaban
    • Nuclear Engineering and Technology
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    • v.52 no.4
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    • pp.819-826
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    • 2020
  • The method of the Laplace transform has been used to obtain an analytical solution of the three-dimensional steady state advection diffusion equation for the airborne radionuclide release from any nuclear installation such as the power reactor in an area source. The present treatment takes into account the removal of the pollutants through the nuclear reaction. We assume that the pollutants are emitted as a constant rate from the area source. This physical consideration is achieved by assuming that the vertical eddy diffusivity coefficient should be a constant. The prevailing wind speed is a constant in 𝑥- direction and a linear function of the vertical height z. The present model calculations are compared with the other models and the available data of the atmospheric dispersion experiments that were carried out in the nuclear power plant of Angra dos Reis (Brazil). The results show that the present treatment performs well as the analytical dispersion model and there is a good agreement between the values computed by our model and the observed data.

A Study on Inter-Ministerial Policy Conflict and Coordination: Focusing on the Science and Technology Basic Law Making Process in Korea (부처간 정책갈등과 조정에 관한 연구 -과학기술기본법 제정과정을 중심으로-)

  • Park Chung-Taek
    • Journal of Science and Technology Studies
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    • v.3 no.1 s.5
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    • pp.105-156
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    • 2003
  • This paper aims to explore the cause and aspect of inter-ministerial policy conflict and its coordination in science and technology policy-making with the case of science and technology basic law-making process in Korea. This law-making processes are analysed through the three periods for the last 10 years starting 1992, such as law-formulation(1st) period, interim law-making (2nd) period, and final law-making(3rd) period. Based on these steps, it tries to concretely describe the phenomenon of policy conflict and the coordination mechanism among government departments and analyses the characteristics of dynamic interaction and mutual adjustment among the related agencies. The analysis is mainly focussed on the underlying causes and determinants of policy conflict, the development and coordination process of the conflict, the strategies and logics of the conflict participants, and eliciting some policy implications for effective policy coordination among government departments. Research results are summarized as follows. First, in science and technology policy-making the main causes of policy conflict among government departments are attributed to the difference of policy-orientation and jurisdiction-orientation of each agency. During the first period, the main aspect of policy conflict was policy-oriented, during the second, the main aspects of policy conflict were both policy-oriented and jurisdiction-oriented, and during the third, policy-oriented conflict was dominant. Second, the dominant typology and strategies of policy coordination which the participants used were vertical-political and horizontal-analytic approach. During the first period, horizontal and analytical approach were used, during the second, horizontal and political approach are mixedly used, and during the third, vertical and political approach were dominantly used. Third, The Korean National Assembly and the ruling party played a pivotal role in science and technology policy-making process(the basic law-making process) in particular during the final period.

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