• Parasites, Hosts and Diseases
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• 제56권5호
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• pp.401-408
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• 2018

Korea is successfully controlled intestinal parasitic infections owing to economic development and high health consciousness. The Division of Vectors and Parasitic Diseases (formerly the Division of Malaria and Parasitology) is in the Center for Laboratory Control of Infectious Diseases of the Korea Centers for Disease Control and Prevention. It has been the governmental agency responsible for controlling and leading scientific research on parasitic diseases. The Division of Vectors and Parasitic Diseases has conducted and funded basic research and disseminated the research results to various medical fields, ultimately promoting public health in Korea. Among the noteworthy achievements of this division are the national surveillance of healthcare-associated parasitic infections, prevention and control for parasitic infections, and the elimination of lymphatic filariasis from Korea. On a broader scale, the division's research programs and academic supports were influential in preventing and treating infectious parasitic diseases through public policies and laws. In this review, we summarize the past and present role of the Division of Vectors and Parasitic Diseases in preventing and treating infectious parasitic diseases in Korea.

• 대한원격탐사학회지
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• 제27권4호
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• pp.495-506
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• 2011

천리안 위성의 궤도상 시험이 위성발사 직후인 2010년 7월부터 2011년 1월까지 약 7개월에 걸쳐 성공적으로 수행되었으며, 과학탑재체인 기상 및 해양탑재체 자료는 2011년 4월부터 공식적으로 배포되고 있다. 이 논문에서는 천리안위성의 궤도상 시험 중 핵심적인 요소인 탑재체 자료의 보정 과정 중 최종 단계인 기하보정의 궤도상 테스트 내용에 중점을 두고 있다. 천리안위성 기하보정 알고리즘의 구조와 내용을 간략하게 소개하였으며, 위성발사 후 행해진 기하보정시스템의 기능 및 검증 테스트의 단계별 과정들과 그 결과를 분석 정리하였다. 실시간 위성자료 전처리 시스템을 통해 확보한 자료들을 이용한 천리안 기하보정알고리즘의 최종 성능테스트는 요구 조건을 만족하는 우수한 정확도를 보여 주었다.

• 한국콘텐츠학회논문지
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• 제10권7호
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• pp.208-219
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• 2010

고지도는 뛰어난 회화성 뿐 아니라 과학성을 가진 정보기록의 문화유산이다. 다양한 학문분야에서 활용되고 있으며 특히 역사지리학에서 과거 지역의 공간복원이나 변화를 살펴볼 수 있는 가장 기초적인 자료이다. 그러나 고지도를 전시에 활용한 콘텐츠 개발에 대한 연구는 매우 부족한 실정이다. 더구나 박물관이나 미술관의 학습프로그램과 융합된 고지도에 대한 콘텐츠연구는 거의 없으며 특히 서양고지도를 활용한 동해 관련의 전시콘텐츠 구성이나 활용방안에 대한 연구는 더욱 찾아보기 어렵다. 본 연구는 우리나라와 동해가 나타난 서양고지도를 전시에 활용하기 위한 교육학습 콘텐츠 구성에 대한 연구이다. 연구결과는 우리나라의 영토와 영해에 대한 학술적인 연구성과를 시각화하여 체계적인 정보로 전달할 수 있다. 그리고 동해에 대한 관심과 동해문제에 대한 재인식의 기회를 마련하고 서양고지도를 박물관이나 문화시설에서의 전시와 교육적 학습자료로 활용하기 위한 콘텐츠 구성과 사이버 전시콘텐츠 구축 및 이를 활용한 역사교육 학습의 기본모델을 제공하는데 그 의미가 있다.

• 한국전자통신학회논문지
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• 제8권11호
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• pp.1625-1632
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• 2013

본 논문에서는 지난 정부에서 추진된 제 3차 지방과학기술진흥정책('08-'12)의 일환으로 추진된 지역 연구활동에 있어서 기초분야 연구 성과물을 대상으로 16개 지역별로 연구 활동도 및 수준, 연구 생산성을 비교 분석 하였다. 각 지역별 연구 생산성의 비교는 연구 인프라(대학, 연구인력 등)의 비편재 요소를 고려하여 비교대상의 객관성을 고려하였다. 특히, 경남지역에서 산출된 대상기간 동안의 모든 기초분야 논문을 모집단으로하여 연구개발 지형도를 구현하고, 기 발표된 해당지역 미래전략산업과의 연계성을 고찰하였다. 따라서 미래전략산업과 연구지형에서 파악된 지역 역량이 집중된 기초분야와의 연계매트릭스를 통해 현재의 내재된 기초역량과 대응되는 미래기술 및 산업을 조망하였다.

• 한국환경성돌연변이발암원학회지
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• 제25권1호
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• pp.6-12
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• 2005

Many compounds might become activated after absorption of UV light energy. In some cases, the resulting molecule may undergo further biological reaction of toxicological relevance related especially to the photo-carcinogenicity resulting from photo-genotoxicity. However, no regulatory requirements have been issued with the exception of guideline issued by the Scientific Committee of Cosmetology, Commission of the European Communities (SCC/EEC) on the testing of sunscreens for their photo-genotoxicity. Thus, the objectives of this study are to investigate the utility of photo-Ames assay for detecting photo-mutagens, and to evaluate its ability to predict rodent photo-carcinogenicity. Photo-Ames assay was performed on five test substances that demonstrated positive results in photo-carcinogenicity tests: 8-methoxypsoralen (photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation), chlorpromazine (an aliphatic phenothiazine an a-adr-energic blocking agent), lomefloxacin (an antibiotic in a class of drugs called fluoroquinolones), anthracene (a tricyclic aromatic hydrocarbon a basic substance for production of anthraquinone, dyes, pigments, insecticides, wood preservatives and coating materials) and retinoic acid (a retinoid compound closely related to vitamin A). Out of 5 test substances, 3 showed a positive outcome in photo-Ames assay. With this limited data set, an investigation into the predictive value of this photo-Ames test for determining the photo-carcinogenicity showed that photo-Ames assay has relatively low sensitivity (the ability of a test to predict carcinogenicity). Thus, to determine the use of in vitro genotoxicity tests for prediction of carcinogenicity,' several standard photo-genotoxicity assays should be compared for their suitability in detecting photo-genotoxic compounds.

• Natural Product Sciences
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• 제26권4호
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• pp.317-325
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• 2020

A new dimer stilbene [Monalittorin (1)] and ten known compounds [engeletin (2), aurantiamide acetate (3), lupeol (4), friedelin (5), quercetin (6), tiliroside (7), rutoside (8), astragalin (9), isoquercitrin (10) and quercimeritroside (11)] have been isolated from the leaves of Monanthotaxis littoralis (Annonaceae). The structures of these compounds were established by interpretation of their data, mainly, HR-TOFESIMS, 1-D NMR (1H and 13C) and 2-D NMR (1H-1H COSY, HSQC, HMBC and NOESY) and by comparison with the literature. The evaluation of their antimicrobial activities against three bacteria (Staphylococcus aureus ATCC 25923, Escherichia coli S2 (1) and Pseudomonas aeruginosa PA01) and three fungal strains (Candida albicans ATCC10231, Candida tropicalis PK233 and Cryptococcus neoformans H99) using broth micro dilution method, showed the largest antimicrobial activities of EtOAc fraction and compounds 1, 5, 6, 8 and 11 (MIC = 8 - 64 ㎍/mL). In addition, EtOAc fraction presented synergistic effect with Vancomycin and fluconazole against the tested microorganisms.

• 공학교육연구
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• 제26권4호
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• pp.22-35
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• 2023

As information and communication technology has developed remarkably, it has become possible to analyze various types of large-volume data generated at a speed close to real time, and based on this, reliable value creation has become possible. Such big data analysis is becoming an important means of supporting decision-making based on scientific figures. The purpose of this study is to develop a big data analysis tool that can analyze large amounts of data generated through engineering education. The tasks of this study are as follows. First, a database is designed to store the information of entries in the National Creative Capstone Design Contest. Second, the pre-processing process is checked for analysis with big data analysis tools. Finally, analyze the data using the developed big data analysis tool. In this study, 1,784 works submitted to the National Creative Comprehensive Design Contest from 2014 to 2019 were analyzed. As a result of selecting the top 10 words through topic analysis, 'robot' ranked first from 2014 to 2019, and energy, drones, ultrasound, solar energy, and IoT appeared with high frequency. This result seems to reflect the current core topics and technology trends of the 4th Industrial Revolution. In addition, it seems that due to the nature of the Capstone Design Contest, students majoring in electrical/electronic, computer/information and communication engineering, mechanical engineering, and chemical/new materials engineering who can submit complete products for problem solving were selected. The significance of this study is that the results of this study can be used in the field of engineering education as basic data for the development of educational contents and teaching methods that reflect industry and technology trends. Furthermore, it is expected that the results of big data analysis related to engineering education can be used as a means of preparing preemptive countermeasures in establishing education policies that reflect social changes.

• 한국의류산업학회지
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• 제25권5호
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• pp.560-567
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• 2023

This study aims to rediscover the industrial value of a borderless service in the hyper-connected era by producing fashion content at the forefront of the cultural industry as XR content and contributing to developing fashion content for edutech. The research method employed design aesthetic theory, while the empirical proposal utilized scientific knowledge information to build a framework for 3D convergence content. The characteristics of fashion content exhibitions that apply the neumorphism technique are as follows: The first is a virtual space that produces clothing culture by type. Africa, where dyeing and crafts are developed, selects a product-oriented exhibition type; Asia, where weaving and textiles are excellent, selects a random movement type; and Europe, where the evolution of clothing design over time is evident, selects a guided movement type to create a three-dimensional fashion edutech. The goal was to produce content. The second is creative reproducibility, which combines a new fashion design that embraces the aura of the original with a trendy sense. The realistic folk costume style of the original allowed for its implementation in the AR exhibition space using historical traditional style techniques such as weaving and textiles. The third is building organic, modular content. By designing and then saving/editing/arranging the basic VP zone for each style, learners and instructors can freely edit the content for each fashion class topic and create various presentations to ensure that it functions as non-face-to-face edutech content around the world.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권5호
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• pp.1666-1689
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• 2021

The red line of Permanent Basic Farmland is the most important part in the "three-line" demarcation of China's national territorial development plan. The scientific and reasonable delineation of the red line is a major strategic measure being taken by China to improve its ability to safeguard the practical interests of farmers and guarantee national food security. The delineation of Permanent Basic Farmland zoning (DPBFZ) is essentially a multi-objective optimization problem. However, the traditional method of demarcation does not take into account the synergistic development goals of conservation of cultivated land utilization, ecological conservation, or urban expansion. Therefore, this research introduces the idea of artificial immune optimization and proposes a multi-objective model of DPBFZ red line delineation based on a clone selection algorithm. This research proposes an objective functional system consisting of these three sub-objectives: optimal quality of cropland, spatially concentrated distribution, and stability of cropland. It also takes into consideration constraints such as the red line of ecological protection, topography, and space for major development projects. The mathematical formal expressions for the objectives and constraints are given in the paper, and a multi-objective optimal decision model with multiple constraints for the DPBFZ problem is constructed based on the clone selection algorithm. An antibody coding scheme was designed according to the spatial pattern of DPBFZ zoning. In addition, the antibody-antigen affinity function, the clone mechanism, and mutation strategy were constructed and improved to solve the DPBFZ problem with a spatial optimization feature. Finally, Tongxu County in Henan province was selected as the study area, and a controlled experiment was set up according to different target preferences. The results show that the model proposed in this paper is operational in the work of delineating DPBFZ. It not only avoids the adverse effects of subjective factors in the delineation process but also provides multiple scenarios DPBFZ layouts for decision makers by adjusting the weighting of the objective function.

• 대한원격탐사학회지
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• 제38권6_3호
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• pp.1817-1826
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• 2022

2012년 구미 불화수소 누출사고 이후 정부는 화학사고의 대응과 수습 등 재난관리를 체계화하고 있다. 특히, 행정안전부는 재난 및 안전관리 기본법을 근거로 화학사고 발생에 따른 주민대피에 대한 명령을 소관하고 있으므로 본 연구에서는 국립재난안전연구원의 화학사고 조사장비를 활용한 화학사고 이후 주민대피 의사결정 지원 및 활용방안을 제시하였다. 화학사고로 인한 과학적 정보수집을 위한 장비 운용체계는 상시와 비상시로 구분하여 원거리 측정장비와 근거리 측정장비의 역할 및 활용목적을 중심으로 제시하였다. 원·근거리 측정장비를 통해 취득된 데이터를 활용하여 비상시에는 화학물질의 검출여부를 모니터링하고, 상시에는 업체별 검출물질에 대한 데이터를 관리함으로써 주민대피 의사결정을 위한 기초자료로 활용할 수 있다. 상시 운용체계에 한하여 장비별로 현장 활용성을 검증하기 위해 화학물질을 측정한 결과, 원거리 측정장비에서는 화학물질의 실시간 검출이 가능함을 확인하였으며, 추후 장비의 측정가능 거리 및 범위에 대한 확인이 필요하다는 점을 확인할 수 있었다. 근거리 측정장비의 경우, 탄화수소 계열의 물질이 주로 검출되며, 온산국가산업단지에 비해 울산·미포국가산업단지에서 높은 수준으로 측정된 것을 확인하였다. 향후 지속적인 데이터 구축을 통해 화학사고 발생에 따른 의사결정 지원을 위한 기초자료로 활용될 수 있을 것으로 기대된다.