• 제목/요약/키워드: Basic Research Program

검색결과 1,856건 처리시간 0.035초

1H NMR-based metabolite profiling of diet-induced obesity in a mouse mode

  • Jung, Jee-Youn;Kim, Il-Yong;Kim, Yo-Na;Kim, Jin-Sup;Shin, Jae-Hoon;Jang, Zi-Hey;Lee, Ho-Sub;Hwang, Geum-Sook;Seong, Je-Kyung
    • BMB Reports
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    • 제45권7호
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    • pp.419-424
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    • 2012
  • High-fat diets (HFD) and high-carbohydrate diets (HCD)-induced obesity through different pathways, but the metabolic differences between these diets are not fully understood. Therefore, we applied proton nuclear magnetic resonance ($^1H$ NMR)-based metabolomics to compare the metabolic patterns between C57BL/6 mice fed HCD and those fed HFD. Principal component analysis derived from $^1H$ NMR spectra of urine showed a clear separation between the HCD and HFD groups. Based on the changes in urinary metabolites, the slow rate of weight gain in mice fed the HCD related to activation of the tricarboxylic acid cycle (resulting in increased levels of citrate and succinate in HCD mice), while the HFD affected nicotinamide metabolism (increased levels of 1-methylnicotineamide, nicotinamide-N-oxide in HFD mice), which leads to systemic oxidative stress. In addition, perturbation of gut microflora metabolism was also related to different metabolic patterns of those two diets. These findings demonstrate that $^1H$ NMR-based metabolomics can identify diet-dependent perturbations in biological pathways.

신체활동 프로그램이 비만유아의 체성분과 기본운동능력에 미치는 영향 (Effects of Physical Activity Program on Body Composition and Basic Motor Skills in Obese Children)

  • 김원준;나승희
    • 한국산학기술학회논문지
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    • 제11권11호
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    • pp.4266-4272
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    • 2010
  • 본 연구는 신체활동 프로그램이 비만 유아의 체성분의 변화와 기본운동능력에 미치는 영향을 알아보고자 하였다. 이를 위해 유아 비만 판정에 쓰이는 카우프지수(Kaup Index)가 20이상인 유아 비만 16명을 실험집단과 통제집단으로 나누어 주 3회식 12주간 신체활동 프로그램을 실시하였다. 본 연구결과는 다음과 같다. 첫째, 신체활동프로 그램이 비만유아들의 체성분의 하위변인 체중, 체지방량, 체지방률, 제지방량, 체수분량 등이 통제집단에 비해 실험집단이 향상되었으며, 두 집단간에 통계적으로 유의미한 차이를 나타냈다. 둘째, 신체활동 프로그램이 비만유아들의 기본운동능력 중 이동운동과 조작운동 등이 통제집단에 비해 실험집단이 향상되었으며, 두 집단간에 통계적으로 유의미한 차이를 나타냈다. 이러한 결과들을 통해 신체활동 프로그램이 비만유아들의 체성분의 변화와 기본운동능력에 긍정적인 영향을 미치는 것으로 나타났다.

방사선 측정기 교정 데이터의 자동처리를 위한 전산프로그램 개발 (Development of a Computation Program for Automatic Processing of Calibration Data of Radiation Instrument)

  • 장지운;신희성;윤청;이윤희;김호동;정기정
    • 비파괴검사학회지
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    • 제26권4호
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    • pp.246-254
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    • 2006
  • 방사선 측정분야에서 사용되는 감마 서베이미터의 교정데이터 자동처리를 위한 전산 프로그램을 개발하였다. 전산 프로그램은 Visual Basic을 기반으로 개발되었으며, 교정과정에 따라 단계별로 윈도우를 제작하고 코드화하였다. 교정 데이터의 자동처리를 위해 Microsoft Excel 프로그램을 제어하여 미리 자동 연산된 엑셀 셀 내에 데이터가 입력되도록 하였다. 개발프로그램 성능평가의 일환으로 검증된 데이터와 프로그램에서 출력된 데이터를 비교한 결과, 교정인자 산출 및 불확도 평가에서 동일한 결과가 나왔다. 또한, 개발프로그램을 교정업무에 적용시킨 결과, 업무의 효율성 및 정확성은 증가하였다.

직업기초능력 프로그램 및 e-Learning 콘텐츠 개발 연구 -전문계고생의 자기개발능력을 중심으로- (The Development of Basic Skill Program and e-Learning Contents ; self-development capability for Vocational High School Students)

  • 변숙영;이수경
    • 디지털콘텐츠학회 논문지
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    • 제11권3호
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    • pp.349-356
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    • 2010
  • 본 연구는 직업교육의 내실화를 위하여 교수·학습능력 신장에 기초가 되는 직업기초능력 향상 프로그램 및 콘텐츠 개발에 그 목적이 있다. 특히, 직업기초능력 영역 중 e-Learning 콘텐츠로 개발하였을 때 효과적일 것으로 관련전문가들이 합의한 자기개발능력을 개발하였다. 자기개발능력은 업무를 추진할 때 스스로를 관리하고 개발하는 능력으로 이 연구에서는 직업과 자기개발, 자기관리 능력으로 프로그램을 구성하여, 사례분석을 중심으로 한 문제해결능력 향상에 초점을 두고, 동영상과 시뮬레이션, 게임 등의 멀티미디어적 전략을 활용하여 e-Learning 콘텐츠를 개발하였다.

마이크로 컴퓨터를 이용한 기본표준자료(基本標準資料) 개발 (Development of Microcomputerized Master Standard Data)

  • 박경수
    • 대한인간공학회지
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    • 제4권1호
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    • pp.3-6
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    • 1985
  • This research developes a microcomputer program for MSD which is one of the most widely llsed predetermined time standards. The program is written in BASIC and designed mainly for desk-top or portable microcomputer to facilitate the development of standard times for time study analysis. A simple case is illustrated to show the program running procedure.

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배전변압기 감시제어 기능이 통합된 지능형 배전자동화 시스템 개발 방향 (Development target of intelligent DAS with the function of distribution transformer monitoring)

  • 하복남;설일호;박신열;정영범
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2005년도 제36회 하계학술대회 논문집 A
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    • pp.554-556
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    • 2005
  • Distribution Automation System (DAS) will provide supervision and remote control of switches and reclosers such as pole pounted switches and pad-mounted switchgears on high voltage distribution line. Kepco had developed basic function such as remote monitoring, remote control, remote measuring and remote setting at first. As a next step, Kepco has been developed diverse application programs such as single line diagram drawing program, relay coordination program, feeder reconfiguration program, over load elimination program, bad data detection program, section load management program, fault processing program and so on. Kepco is examining to develop more powerful functions for special specification of foreign distribution automation system. This paper explains what is the target for overseas DAS market.

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MBTI 기본 프로그램이 간호대학생의 대인관계와 집단응집력에 미치는 영향 (A Study on the Effect of MBTI (Myers and Briggs Type Indicator) Basic Program on the Interpersonal Relationship Between Nursing Science Major Students and Their Cohesion)

  • 황승숙
    • 한국보건간호학회지
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    • 제18권1호
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    • pp.61-73
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    • 2004
  • This study is intended to suggest fundamental data necessary for developing MBTI program that can help improve interpersonal relation skills of nursing science major students and their cohesion. This study is pre-experimental research by one group pretest-post test design to examine the effect of MBTI(Myers and Briggs Type Indicator) basic program on the interpersonal relationship between nursing science major students and their group cohesion and the relationship between interpersonal relationship and their group cohesion. I selected 39 of sophomore students in the department nursing science of K university in I metropolitan city as test group. 35 of them joined post-test. Pretest and MBTI basic program were done before conducting MBTI program. Collected data were analyzed by SPSS window 7.5. The difference in test group before and after conducting program was examined by paired t-test. The correlation between interpersonal relationship and group cohesion was measured by using Pearson Correlation Coefficient. The findings are as follows. $\cdot$ The difference before and after conducting MBTI program by sub-factors of interpersonal relation: There was no significant difference, as the average figure of interpersonal relation in test group was 87.22 before conducting MBTI and 85.08 after conducting MBTI respectively. The average figure of sensitivity among the sub-factors of interpersonal relation was 7.71 before conducting MBTI and reduced to 7.08 after conducting MBTI and there was significant difference between before and after conducting MBTI(t=-2.484, p=.018) $\cdot$ The difference in group cohesion before and after conducting MBTI program: The average figure of group cohesion in test group was 56.68 before conducting MBTI and increased a bit to 56.80 after conducting MBTI\, but there was no significant difference between them. $\cdot$ The relationship between interpersonal relationship and group cohesion before and after conducting MBTI: As the relationship between interpersonal relationship and group cohesion before and after conducting MBTI is examined, there was positive correlation of the significance level. p<.05 before conducting MBTI(r=.320, p=.047), and of the significance level, p<.01 after conducting MBTI(r=.780, p=.000). The investigation on the relation between sub-factors of group cohesion and of interpersonal relation before conducting MBTI basic program revealed that there was positive correlation between openness, reliability, friendliness and satisfaction, and group intervention, between receptivity among group members and reliability, and between group atmosphere and satisfaction. The investigation on the relation between sub-factors of group cohesion and of interpersonal relation after conducting MBTI basic program revealed that there was positive correlation between openness, communication, understanding, friendliness and satisfaction. and group intervention. There was positive correlation between receptivity among group members and openness, communication, understanding, friendliness and satisfaction. There was positive correlation between openness, communication, friendliness and satisfaction, and group atmosphere. Based on the above findings, I realize that MBTI basic program is essential to the improvement of group cohesion. In addition, it is shown that the sub-factors of interpersonal relation such as openness, communication, friendliness, satisfaction, and understanding, and the sub-factors such as group intervention and receptivity among group members are major factors to improve interpersonal relationship and group cohesion. So, the future MBTI program should include sub-programs that deal with the above factors to improve interpersonal relationship and group cohesion.

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소하천 물 환경교육 프로그램 개발 - ENVISION을 중심으로 - (Development of Water Environmental Education Program Using Streams - Focused on ENVISION -)

  • 김정화;이두곤
    • 한국환경교육학회지:환경교육
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    • 제20권4호
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    • pp.12-26
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    • 2007
  • The purpose of this research is to develop a water environmental education (EE) program using streams, based on the core ideas of ENVISION and materializing elements that were extracted in this research. This research realized the elements and presented a model of the water EE program using a local stream. First, this research developed a basic model of a water EE program using streams by extracting 10 materializing elements and realizing the elements in 4 stage-procedural model. The 10 materializing elements were 1. experiencing the process of inquiry, 2. inquiring local environments, 3. self-directing learning and mutual interaction with colleagues, 4. collecting real data and interpreting, 5. utilizing the ICT(information and communication technology), 6. inquiring with the view point of the 'Environmental Studies for EE', 7. inquiring with the watershed concept, 8. inquiring with the integrating and the holistic view point, 9. pursuing the macroscopic understanding about environment, and 10. connecting the real world phenomena with the environmental concepts and theories. This research materialized these 10 elements in 4 stage model, following the previous ENVISION research, which are 1. preparing stage and visual assessment, 2. writing the report of the inquiry plan, 3. collecting the real data in the environment and performing the investigation, and 4. presenting the inquiry results. Second, with using this basic model, this research developed and presented a model of the specific water EE program using a case stream called 'Baig Cheon' stream, which is a local stream. This research is considered to have a considerable meaning in developing a EE program with ENVISION ideas for the watershed concept and inquiry with environmental science using local streams. The developed model can help the professional development of teachers and teacher education of water EE.

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Primary hepatic hemangiosarcoma (HSA) in a Schnauzer dog

  • Kang, Min-Hee;Heo, Ra-Young;Park, Hee-Myung
    • 대한수의학회지
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    • 제49권3호
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    • pp.249-252
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    • 2009
  • A 6-year-old, neutered male, Schnauzer was presented with a one year history of weight loss and exercise intolerance. Physical examination revealed abdominal distention and ecchymosis on the abdominal skin. CBC and serum chemistry profiles revealed anemia and increased serum liver enzymes. Ultrasonography revealed a large liver mass which was characterized by multiple hypoechoic lesions. Postmortem examination revealed primary hepatic hemangiosarcoma. The tumor had extended to the mesentery and diaphragm, but distant metastasis was not found. This case report describes primary hepatic hemangiosarcoma which is very rare in a dog.

인터넷을 활용한 간호정보학 교육 프로그램 개발 (A Development of Internet Based Educational Program for Nursing Informatics)

  • 정면숙
    • 간호행정학회지
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    • 제6권2호
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    • pp.177-194
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    • 2000
  • This study was conducted to develop the internet based Nursing Informatics educational program. This program is consisted of 14 weeks (2 credit, 1 semester) course. Classes include, 'Understanding of Nursing Informatics'. 'Basic computing technologies', 'Basic web page building', 'Navigating Healthcare related Information', 'Nursing Informatics-Practice, Education, Research', 'Issues in Nursing Informatics'. After finishing the course, students' satisfaction about this program was very high and positive. The results suggest that this program is useful to the education of Nursing Informatics and can be used as an alternative teaching method which does restrict time and place in Nursing Education in a newly changing era.

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