• Title/Summary/Keyword: Basic Reproduction Number

Search Result 68, Processing Time 0.027 seconds

Basic reproduction number of African swine fever in wild boars (Sus scrofa) and its spatiotemporal heterogeneity in South Korea

  • Lim, Jun-Sik;Kim, Eutteum;Ryu, Pan-Dong;Pak, Son-Il
    • Journal of Veterinary Science
    • /
    • v.22 no.5
    • /
    • pp.71.1-71.12
    • /
    • 2021
  • Background: African swine fever (ASF) is a hemorrhagic fever occurring in wild boars (Sus scrofa) and domestic pigs. The epidemic situation of ASF in South Korean wild boars has increased the risk of ASF in domestic pig farms. Although basic reproduction number (R0) can be applied for control policies, it is challenging to estimate the R0 for ASF in wild boars due to surveillance bias, lack of wild boar population data, and the effect of ASF-positive wild boar carcass on disease dynamics. Objectives: This study was undertaken to estimate the R0 of ASF in wild boars in South Korea, and subsequently analyze the spatiotemporal heterogeneity. Methods: We detected the local transmission clusters using the spatiotemporal clustering algorithm, which was modified to incorporate the effect of ASF-positive wild boar carcass. With the assumption of exponential growth, R0 was estimated for each cluster. The temporal change of the estimates and its association with the habitat suitability of wild boar were analyzed. Results: Totally, 22 local transmission clusters were detected, showing seasonal patterns occurring in winter and spring. Mean value of R0 of each cluster was 1.54. The estimates showed a temporal increasing trend and positive association with habitat suitability of wild boar. Conclusions: The disease dynamics among wild boars seems to have worsened over time. Thus, in areas with a high elevation and suitable for wild boars, practical methods need to be contrived to ratify the control policies for wild boars.

A Hybrid Bacterial Foraging Optimization Algorithm and a Radial Basic Function Network for Image Classification

  • Amghar, Yasmina Teldja;Fizazi, Hadria
    • Journal of Information Processing Systems
    • /
    • v.13 no.2
    • /
    • pp.215-235
    • /
    • 2017
  • Foraging is a biological process, where a bacterium moves to search for nutriments, and avoids harmful substances. This paper proposes a hybrid approach integrating the bacterial foraging optimization algorithm (BFOA) in a radial basis function neural network, applied to image classification, in order to improve the classification rate and the objective function value. At the beginning, the proposed approach is presented and described. Then its performance is studied with an accent on the variation of the number of bacteria in the population, the number of reproduction steps, the number of elimination-dispersal steps and the number of chemotactic steps of bacteria. By using various values of BFOA parameters, and after different tests, it is found that the proposed hybrid approach is very robust and efficient for several-image classification.

DRINKING AS AN EPIDEMIC: A MATHEMATICAL MODEL WITH DYNAMIC BEHAVIOUR

  • Sharma, Swarnali;Samanta, G.P.
    • Journal of applied mathematics & informatics
    • /
    • v.31 no.1_2
    • /
    • pp.1-25
    • /
    • 2013
  • In this paper we have developed a mathematical model of alcohol abuse. It consists of four compartments corresponding to four population classes, namely, moderate and occasional drinkers, heavy drinkers, drinkers in treatment and temporarily recovered class. Basic reproduction number $R_0$ has been determined. Sensitivity analysis of $R_0$ identifies ${\beta}_1$, the transmission coefficient from moderate and occasional drinker to heavy drinker, as the most useful parameter to target for the reduction of $R_0$. The model is locally asymptotically stable at disease free or problem free equilibrium (DFE) $E_0$ when $R_0$ < 1. It is found that, when $R_0$ = 1, a backward bifurcation can occur and when $R_0$ > 1, the endemic equilibrium $E^*$ becomes stable. Further analysis gives the global asymptotic stability of DFE. Our aim of this analysis is to identify the parameters of interest for further study with a view for informing and assisting policy-makers in targeting prevention and treatment resources for maximum effectiveness.

Sexing of Mouse Embryos by Chromosomal Analysis (염색체 분석에 의한 생쥐 수정란의 성감별)

  • 한용만;김종배;박홍양;정길생;이경광
    • Korean Journal of Animal Reproduction
    • /
    • v.10 no.1
    • /
    • pp.36-41
    • /
    • 1986
  • These experiments were carried out to obtain basic information necessary for sexing embryos by chromosomal analysis. To observe metaphase chromosomes, all embryos developed to blastocysts were cultured in Ho, pp. & Pitts' medium containing 0.001% Colcemid under the gas phase of 5% CO2 in air at 37$^{\circ}C$ for 2 hours. The sex chromosome of mouse embryos shown normal development after culture in medium containing H-Y antiserum (10%, v/v) and complement (20%, v/v) also was confimed by chromosomal analysis. The results obtained in these experiments were summarized as follows: 1. Among 89 mouse blastocysts, the number of embryos identified to have XX and XY chromosome was 22(25%) and 25(28%), respectively and 42(47%) embryos were not identified. 2. Of total 40 mouse balstocysts cultured in medium containing H-Y antiserum and complement, 23(58%) embryos which were able to be discriminated their sex chromosomes were identified to be XX bearing embryos. 3. Sex chromosomes of a number of embryos subjected to chromosomal analysis were not identified. This result may be due to absence or poor quality of metaphase spreads.

  • PDF

Field and Culture Studies on the Growth and Reproduction of Campylaephora hypnaeoides (석묵 (Campylaephora hypnaeoides)의 생장과 성숙에 대한 야외 및 배양 연구)

  • Yoo, Hyun-Il;Kim, Ji-Hwan;Choi, Han-Gil
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.44 no.3
    • /
    • pp.290-297
    • /
    • 2011
  • The phenology of Campylaephora hypnaeoides J. Agardh and optimal conditions for carpospore release, growth and reproduction were examined in the field and in the laboratory from January to December 2007. In the field population of C. hypnaeoides, approximately 50% of the plants were vegetative during the study period. Additionally, the percentages of carposporophytes and tetrasporophytes were maximal in April (37%) and June (57%), respectively. Maximum growth in plant length, dry weight, and hook number coincided with the tetrasporophyte reproductive peak in the field. In culture, carpospore release, sporeling growth and reproduction were affected by environmental factors such as daylength, temperature, and salinity. The liberation of carpospores was maximum under continuous light and at a combination of $15^{\circ}C$ and $10\;{\mu}mol$ photons $m^{-2}\;s^{-1}$. Maximum growth of tetrasporophyte sporelings occurred at a combination of $20\;{\mu}mol$ photons $m^{-2}\;s^{-1}$ of constant light and $25^{\circ}C$. However, the growth of gametophyte sporelings was maximal under $40\;{\mu}mol$ photons $m^{-2}\;s^{-1}$ of constant light and in a combination of $20^{\circ}C$ and 35 psu. The tetrasporophyte sporelings were grew faster than gametophytes, indicating that gametophyte- and tetrasporophyte-sporelings have different physiological responses to irradiance and temperature. Tetrasporangial branches and cystocarps of C. hypnaeoides were produced from carpospores and tetraspores within 1 month, and they were stimulated at high temperature and irradiance levels. In conclusion, C. hypnaeoides should be seeded using carpospores during early winter (November-December) because cystocarps are easily identified by fishermen, and tetrasporophytes grow faster than gametophytes.

Reproducing and Restoring Space Planning for Red Fox (Vulpes vulpes) Restoration - Focusing on Sobaeksan National Park - (여우(Vulpes vulpes) 복원을 위한 증식·복원장 공간 계획에 관한 연구 - 소백산국립공원 지역을 사례로 -)

  • Cho, Dong-Gil;Shim, Yun Jin;Hong, Jin-Pyo;Cha, Jin-Yeol
    • Journal of the Korean Society of Environmental Restoration Technology
    • /
    • v.16 no.4
    • /
    • pp.1-14
    • /
    • 2013
  • A species restoration plan requires a process where the first is to thoroughly study the target species, second is to provide them with an onsite reproduction and adaptation period, and finally, third is to release them to their natural habitat. This study focuses on the space planning for target species' successful onsite reproduction and adaptation. For the study, a site planning near Sobaeksan National Park was implemented with Red Fox's behavior and habitat characteristics in mind for its recovery, reproduction, and natural adaptation. During site selection and planning, the basic aim was to incorporate the existing site as much as possible thus reducing the impact on the environment from the recovery plan. In addition, for a stable recovery of the Red Fox population, the site was classified into three different areas : core area, buffer zone, and transition area. Then, the facilities that help Red Fox's reproduction and adaptation such as reproduction center, foraging site, adaptation training center were planned. Under the condition that the site will be off limit to the public, a limited number of paths for monitoring was provided. For the site's vegetation, the existing species were planted as much as possible with the addition of plants that the Red Fox consume. The facilities included as Red Fox's habitat were fox burrows for hiding and ecological ponds for drinking. From this study, the recovery of the endangered fox species is expected as well as the contribution to an effort to increase of awareness toward the biological resources in Korea through Nagoya protocol. Furthermore, it has the potential to change the public's attitude toward endangered species recovery projects through publicizing and providing experience to the national park visitors.

Effects of Environmental Endocrine Disruptor Bisphenol A on the Reproduction of Xiphophorus maculatus (환경호르몬 비스페놀 A가 Xiphophorus maculatus의 생식에 미치는 영향)

  • Deung, Young-Kun;Kim, Dong-Heui
    • Applied Microscopy
    • /
    • v.34 no.1
    • /
    • pp.43-50
    • /
    • 2004
  • In this study, we examined effects of environmental endocrine disruptor bisphenol A on the reproduction of Xiphophorus maculatus. We exposed the males of X. maculatus to the bisphenol A adjusted to the various concentrations such as 100 ppb, 200 ppb, 400 ppb and 800 ppb for 3 months for the experimental groups and then inbreeded with normal females that was not any treated. We counted the number of second generation for confirmation of fertilizing ability of first generation. Also, we observed the ratios of female and male, the abnormality and mortality, and spermatogenesis of the second generation was exposed to bisphenol A for 6 months. As the result, the number of fry in the second generation was $11.50{\pm}2.22$ in 100 ppb, $6.40{\pm}2.76$ in 200 ppb, $5.70{\pm}1.34$ in 400 ppb and $3.70{\pm}2.11$ in 800 ppb at the experimental groups while it was $19.00{\pm}3.02$ at the control group which was not treated with bisphenol A. This result showed that the experimental groups exhibited a decreasing tendency according to the increase of bisphenol A concentration comparing with the control group. The ratio of female and male of the second generation had no relations with the concentration of bisphenol A, and the ratios of abnormality and mortality were 0%. The spermatogenesis of experimental groups was normal in 800 ppb as well as 100 ppb, 200 ppb, 400 ppb after even 6 months.

A Study on the Splitting Methods in Mouse and Bovine Embryos (생쥐 및 소 수정란의 분할방법에 관한 연구)

  • 조남기
    • Korean Journal of Animal Reproduction
    • /
    • v.11 no.2
    • /
    • pp.127-131
    • /
    • 1987
  • This study was carried out to obtain the basic information on splitting and culture of mouse and bovine embryos. Two-, four-, eight-, cell and morula mouse embryos were digested with pronase, splitted in vitro by micro-glass needel with hand, and bovine embryos were splitted by micromanipulator. The splitted embryos were cultured under 5% of CO2 gas in air at 37$^{\circ}C$ for 48-72 hours. The results obtained in this study were summarized as follows: 1. The mouse and cattle were superovulated by 5IU of PMS and HCG, and 2500IU of PMS and 25mg of PGF2$\alpha$, respectively. The average number of embryos after superovulation were 32.5$\pm$8.2 and 7.5$\pm$3:1, respectively. 2. Out of total 122 embryos splitted, the successful splitting rate was 75.0%, 66.7%, 68.4% and 71.4% in 2-, 4-, 8- and morula embryos in mouse, respectively. There was no different splitting rate between mouse(71.4%) and bovine embryos(66.7%) in morula. 3. The successful culture rate of splitted embryos was 68.0% and 67.9% in mouse and bovine embryos, respectively.

  • PDF

Introduction of Phylodynamics for Controlling the HIV/AIDS Epidemic in Korea

  • Bae, Jong-Myon
    • Journal of Preventive Medicine and Public Health
    • /
    • v.51 no.6
    • /
    • pp.326-328
    • /
    • 2018
  • As over 1000 new cases of HIV/AIDS occur in Korea annually, preventive health programs against HIV/AIDS are urgently needed. Since phylodynamic studies have been suggested as a way to understand how infectious diseases are transmitted and evolve, phylodynamic inferences can be a useful tool for HIV/AIDS research. In particular, phylodynamic models are helpful for dating the origins of an epidemic and estimating its basic reproduction number. Thus, the introduction of phylodynamics would be a highly valuable step towards controlling the HIV/AIDS epidemic in Korea.

INTERVENTION STRATEGY FOR REDUCING ADOLESCENT SMOKING

  • BYUL NIM KIM;CHUNYOUNG OH
    • Journal of the Korean Society for Industrial and Applied Mathematics
    • /
    • v.27 no.4
    • /
    • pp.281-295
    • /
    • 2023
  • This study aims to establish and analyze a mathematical model for the transmission dynamics of male adolescent smoking and to determine an optimal control strategy to reduce male adolescent smoking. We consider three groups in the population: smokers, non-smokers, and temporary nonsmokers. In our model to which optimal control theory was applied, the number of smokers decreased sharply and the number of non-smokers increased significantly. Our simulation results under various control scenarios reveal that integrated control measures(such as prevention, education, and treatment) may be necessary to reduce the growth rate of adolescent smoking. Moreover, we concluded that efforts to encourage current smokers and temporary quitters to quit should be sustained longer than efforts to reduce the rate at which nonsmokers become smokers through smoking prevention education.