The immunohistochemical study has been performed on the distribution of receptors for various growth factors in the newly forming granulation tissues following the guided tissue regeneration procedures. Two specimens from 2 different patients were collected from the newly forming granulation tissues at 2 weeks following GTR procedures using Gore-tex menbrane and rubber dam, respectively. For immunohistochemical localization of each recptor, anti-platelet-derived growth factor $receptor-{\alpha}$, anti-platelet-derived growth factor $receptor-{\beta}$. anti-insulin-like growth factor receptor, anti-basic fibroblast growth factor receptor, anti-transforming growth $factor-{\beta}$ receptor and anti-fibronectin receptor were incubated onto the specimens as primary antibodies. After the reaction, FITC-conjugated second antibodies have been applied. When the total numbers of immunoreactive cells and the true positive cells were counted, there were high variability among receptors tested in the present study. The mean number of immunoreactive cells were highest in the case for anti-IFG-1 receptor. However the number of true positive cells were highest in the case for $TGF-{\beta}$ receptor. The present investigation indicated that the receptor for $TGF-{\beta}$ were stongly expressed in the newly forming granulation tissues following the guided tissue regeneration therapy.
A Study on the make-up expression and purchasing behavior of make-up cosmetics based on the lifestyle. The intention of this study is to classily the consumer group based on the lifestyle, to research the characteristics and desire of the each group, and to find out the differences of the make-up expression and purchasing behavior of make-up cosmetics among each group. The result of this study are as follow; 1. We have obtained seven factors out of twenty six lifestyle items by using AIO lifestyle measurement. The seven factors are make-up high involvement factor, brand loyal factor, make-up bases factor, economical and natural beauty oriented factor, impulsive consumption oriented factor, stubborn choice factor, sensitive to others view factor 2. We have formed four groups based on the seven factors. The four groups are impulsive consumption type, professional make-up type, intentional make-up type, basic type. 3. It was examined that women want to express smart, ellegant and intelligent images form the make-up 4. According to the examination of the differences of the purchsing behavior, only the purchase motive, information source and cosmetics purchase amount per month was differentiate among the groups.
Journal of the Korea Fashion and Costume Design Association
/
v.17
no.1
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pp.13-24
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2015
The purpose of this study is to examine the influences of learners' self-efficacy on class satisfaction in learning practical basic sewing. Questionnaires were distributed to 181 college women students living in the areas of Deagu Metropolitan City and Gyeongbuk Province. The data obtained were analyzed by using various statistical tools: frequency, factor analysis, reliability analysis, correlation analysis, and multiple regression. The self efficacy of learners of practical basic sewing were made up of five factors: ability to manage interpersonal relationships, ability to deal with assigned tasks, anxiety, challenging spirit, and fear. Class satisfaction was composed of the following factors such as interest in class, professors' ability, achievement of class objectives, connectivity, preparation for class, preference for practices, and perfectibility. This study indicated the correlations between sub-variables of learners' self efficacy and class satisfaction. In other words, the higher were the levels of ability to manage interpersonal relationships, and ability to deal with assigned tasks in self efficacy, the higher were the levels of interest in class, professors' ability, achievement of class objectives, preference for practices, and perfectibility in class satisfaction. The factors of ability to deal with assigned tasks, anxiety, and challenging spirit, in learners' self efficacy were found to have statistically significant effects on the achievement of class objectives. The factor of ability to deal with assigned tasks in self efficacy had a statistically significant influence on professors' ability. The factors of ability to deal with assigned tasks, anxiety, challenging spirit and fear were found to have statistically significant effects on all the factors of class satisfaction.
Seo, Ok-Ee;Park, Kwisun;Shin, Suk Kyung;Lee, Sung Jong;Rhie, Won Geun;Lee, Yun Hee
Journal of Korea Technology Innovation Society
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v.16
no.2
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pp.424-443
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2013
National Research Foundation of Korea (NRF) provides underpinning to boost international and domestic competitiveness in basic science and engineering (S&E) research. In 2012, NRF came up with the idea about implementing koreanized grant funding system and a NRF grant funding mechanism on basic research was applied to General Researcher program. The main components of the mechanism are 1) no final evaluation, instead intensive evaluation for next proposal submission, 2) no paper account report, instead reporting it online, 3) no lengthy final report, instead unloading a brief overview of research achievements. For successful establishment of the NRF grant funding mechanism, the quality and quantity-based quantitative guidelines of research achievement for various research areas are essential. In this study, we suggest 3 quantitative indexes and these quantitative guidelines provides a supplementary tool for researcher's capability review. These guidelines will be also useful to elevate the reliability and objectivity of peer review.
The purpose of this study was to find out the kinematical characteristics of arm's basic position in ballet. In order to achieve the purpose of the study, 3D cinematographic analysis was conducted with a ballerina who might performed the perfect arm's basic position. According to the results of this study, it was appeared that the shoulder kept about 78%-82%, the elbow kept about 62%-96%, the wrist kept 52%-109%, and finger kept 48%-110% with the height. Also, movement was formed with $21^{\circ}-77^{\circ}$ of the upper arm angle, $106^{\circ}-164^{\circ}$ of the elbow, $125^{\circ}-140^{\circ}$ of the wrist, and $83^{\circ}-160^{\circ}$ of the shoulder. The left-right ratio of the total arm angle was 98% in the first, second, and third position, and 100% in the forth position. The angle of arm gradient was remained $-68^{\circ}$ in the first position, $-27^{\circ}$ in the second position, $73^{\circ}$ in the third position, and $-11^{\circ}$ in the forth position. Based on the results mentioned above, balance and symmetry of both arms was an important factor in those four positions. Although it is impossible to maintain the position like robot, it may be a good performance if a certain level of extent was remained With respect to this point of view, it may be a good position if the difference between right and left arm in each joint can be remained within 2%. Angle also was an important factor that if the difference in total angle can be remained within 2% it may be an excellent position, there was difference of right and left based on the joint though. Therefore, practice and instruction to make a perfect symmetry as much as possible were needed Also, it would be a good movement if position and angle of joint within 2% difference of right and left arm can be remained In turn, because ballet is movement with expression of the body, beauty of the body and balance of the movement have to be harmonized for beautiful performance. Therefore, it would be a meaningful future study considering the body condition and movement of ballerina to define the beauty.
The world has witnessed tremendous advancements in nano-base applications. Zinc oxide nanoparticles (ZON) are widely used in food industry and medicine. Although their application is of important value, they may cause toxicity to body tissues. Peripheral blood mononuclear cells (PBMCs) proved its efficacy in tissue regeneration especially when it is preconditioned by activated platelet supernatant (APS). The aim of this study is to evaluate the effect of ZON on the gastric mucosa and the therapeutic role of the PBMCs preconditioned by APS in rats. Ten rats were donors and fifty rats were recipients. The recipients were divided into; control group, ZON group (10 mg/kg/day orally for five days) and preconditioned PBMCs group (1×107 once intravenously 24 hours after ZON). Gastric specimens were processed for histological, immunohistochemical, biochemical and quantitative real-time polymerase chain reaction studies. ZON group showed marked structural changes in the gastric mucosa. There was desquamation or deep ulceration of the epithelium. Cytoplasmic vacuoles and pyknotic nuclei were in glandular cells. Reduced proliferating cell nuclear antigen and increased tumor necrosis factor-α were in epithelial cells. There were significant elevation in malondialdahyde and reduction in glutathione, superoxide dismutase, and catalase. Enhancement in mRNA expression of nuclear factor kappa-B and cyclooxygenase-2 was detected. The preconditioned PBMCs group showed significant improvement of all parameters. So, ZON had cytotoxic effects on the gastric mucosa and the preconditioned PBMCs had a therapeutic effect on gastric mucosal damage after ZON.
Objectives: Cancer lethality is usually the result of local invasion and metastasis of neoplastic cell from the primary tumor. Because of their ability to degrade extracellular matrix components, matrix metalloproteinases (MMPs) and basic fibroblast growth factor (bFGF) have been implicated in the breakdown of basement membrane and underlying stroma, thereby facilitating tumor growth and invasion. It has been well established that MMPs and bFGF expression correlate with cervical lymph node metastasis, but studies on expression in the metastatic cervical lymph node itself are not enough. We have analyzed matrix metalloproteinases (MMPs) and basic fibroblast growth factor (bFGF) in squamous cell carcinoma of the head and neck and metastatic cervical lymph node, and evaluated their relationship and clinicophathologic significance. Material and Methods: 20 cases of squamous cell carcinoma of the head and neck were entered on the study of immunohistochemical stains for MMP-9 and bFGF in the obtained tissue from primary tumor and metastatic cervical lymph node. We analyzed the relationship between MMP-9, bFGF expression of the primary tumor and metastatic node with age, sex, T-stage, N-stage, histologic grade, pathologic stage and disease free survival. Results: Expression of MMP-9 and bFGF in cancer cell and metastatic lymph node was higher than that in normal cell and lymph node. According to histologic differentiation, expression of MMP-9 of the metastatic cervical lymph node was higher than primary tumor. Considering to other clinicopathologic factor, no statistical significance was seen in MMP-9 and bFGF. Conclusion: We found that expression of MMP-9 is higher in the metastatic lymph node than primary tumor in the poorly differentiated squamous cell carcinoma. But we don't find out the statistical significance in relation between bFGF and clinical factors. So we guess that some different mechanism of MMP-9 and bFGF in Head & Neck squamous cell carcinoma exist. Further studies will be necessary to establish their pathogenesis in the Head and Neck cancer.
Journal of the korean academy of Pediatric Dentistry
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v.27
no.2
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pp.300-308
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2000
The Fibroblast growth factors(FGFs) plays an important role in the control of osteogenesis during skeletal development. Especially, FGF-2 is a potent mesodermal inducer during embryogenesis and FGF receptors (FGFRs) messages are strongly expressed in developing bones. In this study, we investigated the effect of bFGF on osteopontin(OPN) gene expression in ST-2 cells and tried to elucidate the mechanism of its stimulatory effects. The obtain results were as follows; The treatment of bFGF(1ng/ml) upregulates OPN, fibronectin mRNA levels and downregulates type I collagen mRNA levels. But, there was no remarkable difference in alkaline phosphatase mRNA levels between two groups. The OPN gene expression increased in a dose-dependent manner up to 10ng/ml and OPN gene began to occur at around 3h with continuous increase up to 24h then decreased to basal level at 48h. 30 minutues pretreatment with cycloheximide (500ng/ml), a protein synthesis inhibitor, prior to addition bFGF resulted in blocking bFGF induced OPN expression. These results suggest that bFGF increased the level of OPN mRNA in a dose and time-dependent manner via the synthesis of certain transcriptional regulatory proteins.
Journal of Korea Society of Digital Industry and Information Management
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v.13
no.1
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pp.213-227
/
2017
The recent entry into information society as well as the development and universalization of the Internet through rapid development of ICT technology produced a new educational method called PMP learning. PMP learning overcomes restrictions of previous education methods in terms of time and space and allows the learners to customize their learning environments according to their leads, providing voluntary education that centers on the learners. This study aims to verify the causal relationship in academic achievement of PMP learners through the theory of basic psychological desire, learning satisfaction, and learning metastasis. In order to accomplish this, a study model which applies perceived autonomy, perceived competence, and perceived relationship, which are major variables of the theory of basic psychological desire, was presented. For practical verification of the study model, survey analysis was conducted for students of R High School in Hamyang. Through this, the study aims to provide basic materials for improving the academic achievement of learners in PMP learning. It also plans to suggest educational effects that can be obtained by supporting intrinsic motivation of learners.
Kim, Young-Min;Choi, Joo-Hyoung;Song, Kyung;Kim, Yang-Soo;Kim, Youn-Joong
Applied Microscopy
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v.39
no.1
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pp.73-77
/
2009
Contaminative artifacts such as carbonaceous materials on carbon-coated microgrids are unavoidable, which is induced by electron beam exposure inside electron microscopes. This phenomenon raise a source to produce confusing information to the samples investigated by analytical TEM, which should be alleviated as much as possible. As experimental precautions for reducing this unwanted effect, the use of $LN_2$ cooled anti-contaminator and pre-illumination of electron beam at low magnification can be helpful. Nevertheless, we should be cautious to set an illumination condition for microanalysis because the contaminative effect is dependent with the types of irradiation situations, which is well known to be a decisive factor for causing the carbonaceous artifacts. Accordingly, it is necessary that optimal illumination to minimize the contaminative effect should be selected for improving the accuracy of microanalysis. In this paper, we introduce the practical method to determine the optimal illumination condition by evaluating the contaminative effect as a function of instrumental spot size, which is directly linked with electron current density.
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