• Title/Summary/Keyword: Barrier free

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Anti-oxidant Activity and Skin Barrier Function Measured in Different Solvent Fractions Obtained from Agrimoniae Herba (용아초(龍芽草) 유기용매 분획물의 항산화 및 피부 장벽 개선 효과)

  • Jegeun Han;Min Ju Kim;Hae-Jin Park;Kyung-Ha Lee;Seong-Soo Roh
    • The Korea Journal of Herbology
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    • v.38 no.3
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    • pp.19-26
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    • 2023
  • Objectives : Agrimoniae Herba is a herbal medicine widely distributed in Asia and contains flavonoids including catechin, quercitrin, rutin, hyperoside, and quercetin. This study aimed to investigate the anti-oxidant activity and skin barrier function of different solvent fractions (Hexane; methylene chloride, MC; ethyl acetate, EA; n-butanol, Bu; Water) obtained from Agrimoniae Herba. Methods : Anti-oxidant activity of different solvent fractions obtained from Agrimoniae Herba was investigated through total polyphenol contents, total flavonoid contents, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity, and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity measurements. Then, filament aggregating protein (Filaggrin), Type I collagen, ceramide synthase (CERS) 3, and CERS4 were analyzed to evaluate the skin barrier strengthening effect of different solvent fractions obtained from Agrimoniae Herba on UVB-stimulated HaCaT cells. Results : As a result of measuring total polyphenol contents, total flavonoid contents, DPPH free radical scavenging activity, and ABTS radical scavenging activity, antioxidant activity was found to be excellent in the order of EA > Bu > MC > Hexane > Water. As a result of measuring mRNA gene expression of Type I collagen, Filaggrin, CERS3, and CERS4 after UVB-stimulated was applied to HaCaT cells treated with different solvent fractions obtained from Agrimoniae Herba, it was found to increase significantly in the Bu-treated group. Conclusion : Our findings show that the Bu sample obtained from Agrimoniae Herba has excellent anti-oxidant ability, which increases Type I collagen, Filaggrin, and ceramide synthetase in UVB-stimulated HaCaT cells to control the skin barrier improvement effect.

High Optical Performance of 7" Mini-monitor Based on 2D-3D Convertible Autostereoscopic Display

  • Kim, Sun-Kyung;Park, Sang-Hyun;Kim, You-Jin;Min, Kwan-Sik;Park, Seo-Kyu;Jhun, Chul-Gyu;Kwon, Soon-Bum
    • 한국정보디스플레이학회:학술대회논문집
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    • 2009.10a
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    • pp.1367-1370
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    • 2009
  • We have developed a 2D-3D convertible 7" autostereoscopic mini-monitor with high 3D quality, in which the parallax barrier LCD is attached on the TFTLCD. The excellent optical performance was achieved by design of the ghost free barrier and precise assembly between the barrier layer and the TFT-LCD panel. Our design principle and fabrication technology suppressed 3D cross-talk and improved viewing angle. In this paper, the design and fabrication process of the 3D mini-monitor are described. The evaluation for the 3D performance is also discussed.

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Improvement of skin barrier function using lipid mixture

  • Park, Won-Seok;Son, Eui-Dong;Nam, Gae-Won;Park, Jong-Ho
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.27 no.1
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    • pp.53-72
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    • 2001
  • Dry skin is caused mainly by the perturbation of stratum corneum lipids which affected by ageing, change of season, excess use of surfactant and the effect of disease like atopic dermatitis and psoriasis. Intercellular lipid structures in stratum corneum are responsible for the barrier function of mammalian skin. The major lipd classes that can be extracted from stratum corneum are ceramides, cholesterol and fatty acid, which make up approximately 50, 25, 10 percent of the stratum corneum lipid mass, respectively. Small amount of cholesterol sulfate, phospholipids, glycosylceramide and cholesterol esters are also present. Recent studies have shown that application of one or two these lipids to the perturbed skin delays barrier recovery; only equimolar mixtures allow normal recovery. We observed that barrier recovery rate was improved in hairless mouse by topical application of single neutral lipids (ceramide, free fatty acid, cholesterol) and lipid mixtures. Whereas the application of single lipid didn’t allows a significant enhancement comparing with normal barrier repair, the equimolar mixtures of 3 components(including synthetic pseudoceramide PC104) improved barrier repair, as assessed by the transepidermal water loss. At clinical study to the volunteers aged over sixty, skin dryness recuperated by the increase of moisture(capacitance) and the reduction of scaling. Utilization of physiologic lipid mixture containing natural ceramides or synthetic pseudoceramide could lead to new forms of topical therapy for the dryness and dermatoses(e.g., psoriasis, atopic dermatitis and irritant dermatitis).

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Effect of Surface Treatment of Polycarbonate Film on the Adhesion Characteristic of Deposited SiOx Barrier Layer (폴리카보네이트 필름 표면 처리가 증착 SiOx 베리어층 접착에 미치는 영향)

  • Kim, Gwan Hoon;Hwang, Hee Nam;Kim, Yang Kook;Kang, Ho-Jong
    • Polymer(Korea)
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    • v.37 no.3
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    • pp.373-378
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    • 2013
  • The interfacial adhesion strength is very important in $SiO_x$ deposited PC film for the barrier enhanced polycarbonate (PC) flexible substrate. In this study, PC films were treated by undercoating, UV/$O_3$ and low temperature plasma and then the effect of physical and chemical surface modifications on the interfacial adhesion strength between PC film and $SiO_x$ barrier layer were studied. It was found that untreated PC film shows significantly low interfacial adhesion strength due to the smooth surface and low surface free energy of PC. Low temperature plasma treatments resulted in the increase of both surface roughness and surface free energy due to etching and the appearance of polar molecules on the PC surface. However, UV/$O_3$ treatment only shows the increase of surface free energy by developed polar molecules on the surface. These surface modifications caused the enhancement of surface interfacial strength between PC film and $SiO_x$ barrier. In the case of undercoating, it was found that the increase of surface interfacial strength was achieved by adhesion between various acrylic acid on acrylate coated surface and $SiO_x$ without increase of polar surface energy. In addition, the barrier property is also improved by organic-inorganic hybrid multilayer structure.

A Study on the Analysis of the Current and the Demand of the House for the Blind (시각장애인 주택의 실태 및 요구도 분석에 관한연구)

  • Kim, Sang-Woon;Kang, Byoung-Keun;Soong, Ki-Chang;Park, Kwang-Jae;Yun, Young-Sam;Jung, Eun-Young
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.15 no.1
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    • pp.41-52
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    • 2009
  • Increasing the old and the senile disability, it is increased that the demand of barrier-free house for the disabled, the senior, the pregnant and the young is strongly increasing recently. In this reason, this study focuses the problems of the house which is used by the Blind through the investigation of current status and tries to find out the differences between disability's demand and current design of their house. As well, through the research and analysis some cases of the residential alterations this study verifies what the demand is on each room and their need is committed correctly during the residential alterations. It is the purposes of this study finding the problems through these research and analysis. Thus this study investigates houses of the Blind and finds out their house type, scale and daily life through the statistical data and documentary survey and also, investigates current status of their house. The basic standard for the current status and the demand analysis is researched by the barrier factors which are deducted from the former study.

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Effects of the Thickness of Bond Coating on the Thermal Stress of TBC (접착층의 두께가 용사 열차폐 코팅의 열응력에 미치는 영향)

  • 김형남;최성남;장기상
    • Proceedings of the KWS Conference
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    • 2000.04a
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    • pp.228-231
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    • 2000
  • Based on the principle of complementary energy an analytical method is developed for determining thermal stress distribution in an thermal barrier coating. This method gives the stress distributions which satisfy the stress-free boundary conditions at the edge. Numerical examples are given in order to verify the method and to investigate the thickness effects of the ZrO$_2$-8wt%Y$_2$O$_3$ top coat on the integrity of thermal barrier coating consisted of IN738LC substrate and MCrAlY bond coat.

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Case Study on Design Characteristics of Outdoor Space for Elderly (고령자 주거시설의 외부공간 디자인 특성에 관한 사례연구)

  • Hong, Kwang-Ho;Lee, Shi-Young
    • The Journal of Natural Sciences
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    • v.17 no.1
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    • pp.65-77
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    • 2006
  • This study aims at providing suitable outdoor spaces for physical, social, and psychological condition of Korea elderly, examining design characteristics and presenting design guideline of outdoor space for elderly. To do this, this study examined previous research papers and scholastic writings, related to elderly housing, and analyzed existing outdoor space for elderly. Additionally evaluation of usage pattern and physical trace carried out four silver towns. As a result, first, the study showd that characteristics of outdoor space are related to safety, amenity, recognition and efficiency. Second, types of outdoor space in elderly related facilities are very limited in verity, just facilitating with rest space, sport space, and garden space. Third, from a standpoint of barrier-free-design, four silver town cases are not carefully concerning about outdoor space for elderly. These spaces should be designed for both neighborhood and elderly people.

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Evaluation of sound insulation performance according to aperture conditions under the flush door (세대내 플러시 도어의 하부틈새 조건에 따른 차음성능 평가)

  • An, Ji-Hyeong;Kim, Myung-Jun;Lee, Min-Joo
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2007.11a
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    • pp.153-158
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    • 2007
  • Sound insulation performance of the flush door in the apartment unit was recently decreased due to the door for the purpose of barrier free. To evaluate sound insulation, the test for 13 kinds of flush doors was performed as aperture conditions under the flush door. and the measured value was compared with the predicted values of theoretical sound transmission. The results were summarized follow; First, in case of doors with aperture by barrier free, the single number quantities ($D_{pw}$) were evaluated $21{\sim}23dB$. Whereas, in case of existing door with frame, $D_{pw}$ was evaluated $28{\sim}31dB$. And in case of sealed doors, $D_{pw}$ was evaluated $31{\sim}34dB$. Second, the measured $D_{pw}$ was good agreement with the predicted $D_{pw}$ in condition of small aperture.

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Development of the Accessibility Guidelines for Mobility Handicapped Persons in Passenger Ship

  • Kim, Hongtae;Lee, Jong-Gap
    • Journal of Navigation and Port Research
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    • v.36 no.9
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    • pp.763-767
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    • 2012
  • The ratio of the mobility handicapped person is about 25.8% of the total population in Korea(MCT, 2006). In order to prepare for the enforcement of the "Transportation Services Improvement Act for the Mobility Handicapped People"(MCT, 2006), various equipments and installations should be developed to ensure appropriate safety level for the mobility handicapped persons in maritime transportation. While approximately 10 million people are using domestic passenger vessels annually, preferences for maritime transport is very low, especially for the mobility handicapped. This study reviewed a current status of the mobility handicapped person in domestic passenger ship and analysed the improvement plan for them. To investigate the current status of domestic passenger vessel usage by the mobility handicapped, to analysis the requirements for amenities necessary for the mobility handicapped and select the ones to be developed based on the investigated results and to do feasibility study of barrier-free ship.

Augmented Reality Pre-inspection for Barrier-Free Authentication (증강현실 기술을 활용한 BF 인증 사전 검사 방법)

  • Shin, hyung-woo;Shin, yoon-seok;Yu, Wi-Seong
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2022.11a
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    • pp.233-234
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    • 2022
  • In Korea, various policies are implemented so that the socially disadvantaged (disabled, elderly, pregnant women, temporary disabled, etc.) can easily access individual facilities and areas. As the nation's interest in the socially disadvantaged increases, the need for BF certification is also emerging in buildings in private facilities. However, this system requires a lot of cost and time in the examination process, so if certification fails, social costs and time losses are high. To solve this problem, this paper presents a measurement plan for mixed reality devices using HoloLens, a mixed reality device hardware that can pre-check BF certification based on augmented reality, and Unity 3D, MRTK, a development tool.

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