• 한국광학회지
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• 제23권4호
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• pp.159-166
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• 2012

본 연구에서는 질소와 산소의 회전 라만 신호를 측정하여 낮 시간 온도 측정이 가능한 라이다 시스템을 자체 개발하였다. 태양광에 의한 배경신호를 줄이기 위하여 파장의 폭이 좁고(0.5 nm) 제거율이 높은($10^{-6}$) 회절판과 간섭필터를 이용하였다. 개발된 장치의 성능을 검증하기 위하여 라이다를 수평방향으로 조사하여 온도 특성을 얻고 기상청에서 주어지는 값과 비교하여 상관관계가 일치함을 알 수 있었다. 그리고 수직온도분포로 얻기 위하여 수평으로 얻은 검정 값을 사용하였다. 또한 수직방향으로 조사하여 미국 표준 데이터와 비교하였으며, 존데 데이터와 검정을 통한 본 연구의 결과를 비교하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8093-8100
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• 2016

Background: Genetic and environmental factors play important roles in pathogenesis of digestive tract cancers like those in the esophagus, stomach and colorectum. Folate deficiency and methylenetetrahydrofolate reductase (MTHFR) as an important enzyme of folate and methionine metabolism are considered crucial for DNA synthesis and methylation. MTHFR variants may cause genomic hypomethylation, which may lead to the development of cancer, and MTHFR gene polymorphisms (especially C677T and A1298C) are known to influence predispositions for cancer development. Several case control association studies of MTHFR C677T polymorphisms and colorectal cancer (CRC) have been reported in different populations with contrasting results, possibly reflecting inadequate statistical power. Aim: The present meta-analysis was conducted to investigate the association between the C677T polymorphism and the risk of colorectal cancer. Materials and Methods: A literature search of the PubMed, Google Scholar, Springer link and Elsevier databases was carried out for potential relevant articles. Pooled odds ratio (OR) with corresponding 95 % confidence interval (95 % CI) was calculated to assess the association of MTHFR C677T with the susceptibility to CRC. Cochran's Q statistic and the inconsistency index (I2) were used to check study heterogeneity. Egger's test and funnel plots were applied to assess publication bias. All statistical analyses were conducted by with MetaAnalyst and MIX version 1.7. Results: Thirty four case-control studies involving a total of 9,143 cases and 11,357 controls were retrieved according to the inclusion criteria. Overall, no significant association was found between the MTHFR C677T polymorphism and colorectal cancer in Asian populations (for T vs. C: OR=1.03; 95% CI= 0.92-1.5; p= 0.64; for TT vs CC: OR=0.88; 95%CI= 0.74-1.04; p= 0.04; for CT vs. CC: OR = 1.02; 95%CI= 0.93-1.12; p=0.59; for TT+ CT vs. CC: OR=1.07; 95%CI= 0.94-1.22; p=0.87). Conclusions: Evidence from the current meta-analysis indicated that the C677T polymorphism is not associated with CRC risk in Asian populations. Further investigations are needed to offer better insight into any role of this polymorphism in colorectal carcinogenesis.

• Asian Pacific Journal of Cancer Prevention
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• 제17권8호
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• pp.4149-4154
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• 2016

Background: Cervical carcinoma is one of the main causes of mortality in women worldwide as well as in India. It occurs as a result of various molecular events that develop from the combined influences of an individual's genetic predisposition and external agents such as smoking and menstrual hygiene, for example. However, infection with human papillomavirus (HPV) is the established major risk factor. The aim of the current study was to investigate p16 CpG island methylation and establish any correlation with mRNA expression in north Indian population. Materials and Methods: We analyzed 196 woman volunteer out of which 98 were cases and 98 healthy controls. For the analysis of methylation pattern, DNA extracted from blood samples was modified with a bisulfate kit and used as template for methylation specific PCR (MSP). Quantitative real-time PCR (QRT-PCR) was performed to check mRNA expression. Results: Correlation between methylation status of p16 gene and poor menstrual hygiene was significant (p=0.006), high parity cases showed methylation of p16 gene (p=0.031) with increased risk up to 1.86 times for cervical cancer and smoking was a strong risk factor associated with cervical cancer. We analyzed methylation pattern and found 60.3% methylation in cases with low mRNA expression level (0.014) as compare to controls (1.24). It was also observed that promoter methylation of p16 gene was significantly greater in FIGO stage III. Conclusions: We conclude that p16 methylation plays an important role in cervical cancer in the north Indian population and its methylation decreases mRNA expression. It can be used as an important and consistent blood biomarker in cervical cancer patients.

• 치위생과학회지
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• 제20권2호
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• pp.82-88
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• 2020

Background: The incidence of dementia in Korea is a serious social problem, as the number of patients with dementia is increasing with a decrease in the age of dementia onset dementia is associated with oral disease among various causes, but there is very low awareness of the relationship between dementia and oral health. Therefore, in view of the above, we aimed to check oral health promotion and dementia prevention behaviors and use them as basic data for preventing dementia. Methods: In this study, we conducted a month-long survey of people aged 40 years and above living in South Korea, and reclaimed 140 survey questionnaires. Frequency analysis was performed for the perception level of the relationship between dementia and oral health, and the demographic characteristics assessed according to the perception level. Independent t-tests were performed for the mean comparison between oral health promotion and dementia prevention behaviors. Correlation analysis was performed for the relationship between the three variables (oral health promotion and dementia prevention behaviors, the perception level of the relationship between them). Results: The results showed that groups with a high level of awareness of the relationship between dementia and oral health were more likely to develop oral health promotion and dementia prevention behaviors (p<0.01). In addition, the higher the level of awareness related to dementia and oral health, the greater the likelihood of oral health and dementia prevention behaviors (p<0.01). Conclusion: Therefore, we should try to improve dementia prevention and oral health promotion by providing accurate knowledge and awareness of the relevance between dementia and oral health.

• 치위생과학회지
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• 제20권2호
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• pp.67-73
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• 2020

Background: Owing to the increase in the aging population, the health problems of the elderly have become important social problems. Social support has a positive effect on improving the quality of life and prolonging the life of elderly people. It is one of the major factors that affects the oral health status of elderly people. The purpose of this study was to examine the relationship between oral health status and social support in elderly people using representative data. Methods: In this study, data from a community health survey in 2015 involving 63,929 elderly people aged over 65 years were analyzed. T-test and ANOVA analyses were performed to compare the general characteristics of and perception about social support. Additionally, a linear regression analysis was performed to confirm the relationship between perceptions about social support and subjective oral health status. Results: We found that sex, age, household income, education level, the presence of a spouse, existence of an unmet dental need, and regular oral check-up had a significant effect on subjective oral health status (p<0.05). In addition, when controlled for all factors, social support has a significant impact on subjective oral health status. Conclusion: The findings indicate that social support is associated with the subjective oral health status of Korean elderly. This suggests that community-level or government investment is required to improve the oral health of the elderly. In particular, policy interventions such as the establishment of facilities that promote social networks, especially facilities based on friendship networks, are needed.

• 한국환경보건학회지
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• 제39권6호
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• pp.532-540
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• 2013

Background: Exposure factors for consumer products have been developed since the 1980s. Such exposure factors are important in risk assessment. Since the exposure/use patterns of consumer products in a country may reflect its respective cultural, meteorological, and socio-economic circumstances, unique Korean exposure factors for consumer products are needed. Such exposure factors are required for newly-enacted chemical regulations in Korea. For this review, published papers and survey reports on exposure factors of consumer products were examined for their assessment methodologies. Results: Investigation into exposure factors for consumer products used a variety of methods: home visit, online, telephone, and mail surveys using questionnaires; face to face interviews; modeling using a constructed database; and direct measurement. To collect more accurate exposure information or to check the reliability of the sampling method, some studies were repeated using the same questionnaire, in-home observation, direct measurement of usage, and videotaping. In Korea, nationwide exposure surveys were conducted five times over five years to obtain Korean exposure factors. However, with the exception of the $5^{th}$-year study, the surveys were online questionnaires and only the $5^{th}$-year study validated the accuracy of exposure information by re-visits and direct measurement. Conclusion: Accurate exposure factors are an essential part of risk assessment to assure safe use of consumer products. For better and safer management of consumer products, accurate exposure factors in Korea should be assessed for various exposure pathways.

• Journal of Radiation Protection and Research
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• 제41권2호
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• pp.87-91
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• 2016

Background: A hand-held detector for an emergency response was developed for nuclide identification and to estimate the information of the ambient dose rate in the scene of an accident as well as the radioactivity of the contaminants. Materials and Methods: To achieve this, the most suitable sensor was first selected as a cadmium zinc telluride (CZT) semiconductor and the signal processing unit from a sensor and the signal discrimination and storage unit were successfully manufactured on a printed circuit board. Results and Discussion: The performance of the developed signal processing unit was then evaluated to have an energy resolution of about 14 keV at 662 keV. The system control unit was also designed to operate the CZT detector, monitor the detector, battery, and interface status, and check and transmit the measured results of the ambient dose rate and radioactivity. In addition, a collimator, which can control the inner radius, and the airborne dust sampler, which consists of an air filter and charcoal filter, were developed and mounted to the developed CZT detector for the quick and efficient response of a nuclear accident. Conclusion: The hand-held CZT detector was developed to make the in-situ gamma-ray spectrometry and its performance was checked to have a good energy resolution. In addition, the collimator and the airborne dust sampler were developed and mounted to the developed CZT detector for a quick and efficient response to a nuclear accident.

• 대한간호학회지
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• 제4권1호
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• pp.50-63
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• 1974

Health at infancy and early childhood is considered an important factor for healthy life thereafter. Concept of nursing is inclusive not only of physical care but also psycho-social aspect in order to help achieve maximum state of wellness. Statistical studies reveal concept and structure of family and home tends to change towards nuclear type, ratio of female occupancy tends to increase. These tendencies will influence the method of infants and children. Purpose of this study is to investigate the characteristics of mothers and their children with and without occupation, method of nurturing and analyse data according to various variables, in arnder to give data for care for infants and children. During the period of June 12 though July 22, 1973, 98 mothers and their 224 children; 53 mothers with occupation with 110 children and 45 mothers without occupation with 114 children were Interviewed indirectly through check list. Results of the studies are as follows: 1. Hypothesis 1 ; Tendencies of finger sucking will be greater in children of occupant mothers due to lack of maternal love. Through chi-square examination significant difference is revealed by P>0.05 level, therefore Hypothesis 1 is rejected. (X²=0.24) 3. Hypothesis 2; of occupant mothers tend to have had wanted number of children through family planning. Ratio of wanted versus unwanted children were tested and significant difference is revealed by P<0.05 1eve1. Hypothesis 2 is supported. (X²=8.398). 3. Hypothesis 3: Non-occupant mothers tend to cuddle more while feeding infants. Significant difference Is revealed through Chi-square test by P〈0.05 level. Hypothesis 3 is rejected. (X²=4.34) Conclusion and recommendations: Occupant mothers' higher degree of interest and consideration compared to that of non-occupant mothers in regard to nurturing of their children have been ascertained by this study. These results fight have come up due to the differences of socioeconomic and cultural status of respondents. Further studies on each variable between mothers with and without occupation with similar socio-economic and cultural background are recommended.

• 대한간호학회지
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• 제23권4호
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• pp.617-630
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• 1993

Factors related to health promotion activities and quality of life in Korean women with arthritis have not been clearly identified. Predictors of health promotion might be identified that will enhance the well - being of this group. Accordingly, the findings of the study will contribute additional information about the relationship between health promotion and quality of life and will add to the research on quality of life of individuals with a leading cause of disability--arthritis. The purpose of the study was to examine the relationship of selected background factors (years of illness, perceived severity of illness, uncertainty in illness), perceived self- efficacy, and health promoting behaviors to the quality of life of Korean women with arthritis. A cross - sectional descriptive design was used in this study to investigate relationships among the variables of interest. The sample was composed of 96 women who had arhtrits and visited large university hospital in Seoul for regular check up or pre-scription of medication. The purpose of a descriptive correlational design was to determine the absence or presence of relationships among variables that were measurable (Polit & Hungler, 1981, p.147). The design of this study was appropriate because it yielded answers to the research questions and hypotheses regarding the relationships among the model variables. the Questionnaire contained demographic information, translated Mishel Uncertainty in illness Scale-Community form (MUIS-C) (Mishel, 1987), translated and modified Disease Course Graphic Scale(DCGS) which was developed by Braden (1990), translated Sherer. et al.’s General Self-Efficacy Scale (1982), The Health -Promoting Lifestyle Profile (HPLP), developed by Walker, Sechrist, and Fender (1987) and traslated to Korean by Ha, and quality of life was measured by Face Scale (Andrew, 1976). Several steps of verification for the translation process were carefully conducted. Data analysis included descriptive correlational statistics and multiple regression techniques. Health promotion was the only contributor to pre-dict quality of life. Results showed that enabling cognitive perceptual factor (self-efficacy) mediates the disruptive force (uncertainty in ill-ness) on achieving a health promoting self- help behavior. The findings of this study also indicated that illness - related variable of severity of illness was mediated by health promotion, which buffered it's impact on quality of life.

• 한국환경과학회지
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• 제26권9호
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• pp.999-1011
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• 2017

In this study, the Chiu-2D velocity-flow rate distribution based on theoretical background of the entropy probability method was applied to actual ADCP measurement data of Gangjung Stream in Jeju from July 2011 to June 2015 to predict the parameter that take part in velocity distribution of the stream. In addition, surface velocity measured by SIV (Surface Image Velocimeter) was applied to the predicted parameter to calculate discharge. Calculated discharge was compared with observed discharge of ADCP observed during the same time to analyze propriety and applicability of depth of water velocity average conversion factor. To check applicability of the predicted stream parameter, surface velocity and discharge were calculated using SIV and compared with velocity and flow based on ADCP. Discharge calculated by applying velocity factor of SIV to the Chiu-2D velocity-flow rate distribution and discharge based on depth of water velocity average conversion factor of 0.85 were $0.7171m^3/sec$ and $0.5758m^3/sec$, respectively. Their error rates compared to average ADCP discharge of $0.6664m^3/sec$ were respectively 7.63% and 13.64%. Discharge based on the Chiu-2D velocity-flow distribution showed lower error rate compared to discharge based on depth of water velocity average conversion factor of 0.85.