• 설비공학논문집
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• 제22권11호
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• pp.745-750
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• 2010

Since the implementation of the LMO Law in Korea, the importance of the design qualification of BSL3 lab. is emphasizing. In this study, multizone simulation for three kind of biohazard scenarios using CONTAM is performed for design qualification of BSL3 lab. Also, in the case of unexpected spread of contaminants such as Influenza A virus(H1N1) in BL3 zone, the design qualification is carried out for diffusion and decontamination of contaminants according to differential pressure of BSL3 anteroom and door area of BSL3 lab. Also, in this study, appropriateness of laboratory room differential pressure and air flow rate to maintain pressure difference between laboratory rooms, and energy consumption due to air change rate variation according to door area in BL3 lab. Simulation results show that these approach methods are used as a tool for the design and verification of BL3 lab.

• 설비공학논문집
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• 제24권11호
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• pp.813-822
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• 2012

In this study, the multizone simulation for biosafety of BSL3 lab. and energy simulation are carried out simultaneously by using linked model of CONTAM and TRNSYS. In BSL3 lab., annual energy consumption is approximately five to ten times more than the magnitude of the office building. This is because required air change rate is extremely large and it is difficult to maintain room pressure difference efficiently. To maintain pressure difference between laboratory rooms through sealing condition of doors and proper airflow control is significant. In this study, to predict indoor environment of the BSL3 lab.(Influenza A research lab.), the multizone simulation for four kinds of biohazard scenario is also performed as part of risk assessment. Multizone and energy simulation results by using linked model show that these approaches are used as a tool for the energy efficient design and operation method for the safer BSL3 lab. facilities.

• 설비공학논문집
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• 제21권12호
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• pp.671-677
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• 2009

In Korea, since the implementation of the LMO Law, the interest of biosafety level 3(BL3) lab. is increasing. In this study, using CONTAM which is applying multizone modelling, the multizone simulation for design verification of BL3 lab. is performed. In BL3 lab., because required air change rate is greater than general estimated air-conditioning load and it is difficult to maintain room pressure difference efficiently, to maintain pressure difference between laboratory rooms is important through sealing condition of doors and proper airflow control of laboratory rooms. In this study, about BL3 lab,(M. tuberculosis research lab.), the multizone simulation for four kind of biohazard scenarios is carried out in the case of unexpected spread of contaminants in the laboratory room, anteroom, corridor and inside of BSC. Multizone simulation results show that these approach methods are used as a tool for the design and verification of BL3 lab.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2009년도 하계학술발표대회 논문집
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• pp.745-750
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• 2009

In Korea, since the implementation of the GMO Law, the intrest of biosafety level 3(BL3) lab. is increasing. In this study, using CONTAM which is applying multizone modelling, the multizone simulation for design verification of BL3 lab. was performed. In BL3 lab., because required air change rate is greater than general estimated air-conditioning load and it is difficult to maintain room pressure difference efficiently, to maintain pressure difference between laboratory rooms is important through sealing condition of doors and proper airflow control of laboratory rooms. In this study, about BL3 lab.(M. tuberculosis research lab.), the multizone simulation for four kind of biohazard scenarios was performed in the case of unexpected spread of contaminants in the laboratory room, anteroom, corridor and inside of BSC. Multizone simulation results show that these approach methods are used as a tool for the design and verification of BL3 lab.