• 대한간호학회지
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• 제35권5호
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• pp.943-954
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• 2005

Purpose: The purpose of this study was to identity the effects of a health promotion program for rural elderly on health promotion lifestyle and health status. Method: The study was a nonequivalent control group pre-post experimental design. Data collection was performed from April 12th, 2003 to August 2nd, 2003. The subjects were selected at Mari Myun Geochang Gun in Korea. 44 elders were in the experimental group and 45 elders were in the control group. The 16-week health promotion program was given to the experimental group. Data was analyzed by descriptive statistics, $x^2$-test, t-test, and ANCOV A test with SPSS/Win 10.0 program. Result: The experimental group showed higher scores of a health promotion lifestyle and perceived health status than the control group. In addition, systolic BP, heart rate, body fat and glucose of the experimental group were lower than the control group. Waist flexibility, left hand grip power, back strength and leg strength of the experimental group were higher than the control group. However, there were no significant differences in diastolic BP, total cholesterol and right hand grip power between the two groups. Conclusion: This health promotion program for rural elderly can be recommended as an effective nursing intervention in rural communities.

• 대한간호학회지
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• 제44권4호
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• pp.437-445
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• 2014

Purpose: This study was done to identify pain perception (P-PER) by nurses and pain expression (P-EXP) by patients in critical care units (ICUs) and degree of agreement between nurses' P-PER and patients' P-EXP. Methods: Nurses' P-PER was measured with a self-administered questionnaire completed by 99 nurses working in ICUs during May, 2013. Patients' P-EXP was measured with the Critical Care Non-Verbal Pain Scale through observations of 31 ICU patients during nine nursing procedures (NPs) performed between May and July, 2013. Results: Nurses' P-PER was from 4.49 points for nasogastric tube (NGT) insertion to 0.83 for blood pressure (BP) measurement based on a 9-point scale, Patients' P-EXP was 4.48 points for NGT to 0.18 for BP measurement based on a 10-point scale. Eight NPs except oral care showed higher scores for nurses' P-PER than for patients' P-EXP. Position change (p=.019), subcutaneous injection (p<.001), blood sugar test (p<.001), and BP measurement (p<.001) showed significant differences between nurses' P-PER and patients' P-EXP. Conclusion: Nasogastric tube (NGT) insertion was scored highest by both nurses and patients. Eight NPs except 'oral care' showed nurses' P-PER was higher or similar to patients' P-EXP, which indicates that nurses may overestimate procedural pain experienced by patients.

• 대한수의학회지
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• 제43권4호
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• pp.657-666
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• 2003

The present study was undertaken to evaluate the potential adverse effects of 2-BP on pregnant dams and embryo-fetal development after maternal exposure during the gestational days (GD) 6 through 19 in Sprague-Dawley rats. The test chemical was administered subcutaneously to pregnant rats at dose levels of 0, 375, 750 and 1250 mg/kg/day. During the test period, clinical signs, mortality, body weights and food consumption were examined. All dams were subjected to caesarean section on GD 20 and their fetuses were examined for external, visceral and skeletal abnormalities. At above 750 mg/kg, toxic effects including signs of toxicity, suppressed body weight, decreased gravid uterine weight and reduced food intake were observed in pregnant dams. An increase in the fetal deaths, a decrease in the litter size, a reduction in the fetal body weight and an increase in the incidence of fetal morphological alterations were also found. There were no adverse effects on either pregnant dams or embryo-fetal development at a dose level of 375 mg/kg. These results suggest that a 14-day subcutaneous dose of 2-BP is embryolethal and teratogenic at above 750 mg/kg/day in pregnant rats. In the present experimental condition, the no-observed-adverse-effect level of 2-BP is considered to be 375 mg/kg/day for dams and embryo-fetuses, respectively.

• 보건교육건강증진학회지
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• 제26권2호
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• pp.135-148
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• 2009

Objectives: The purpose of this study is to identify the characteristics between therapy continuity group and therapy discontinuity group and to develop management program for Korean patients with hypertension and diabetes. Methods: The subject of the study were 109 therapy continuity and 66 therapy discontinuity of Korea hypertension diabetes Daegu initiative. The data collection was performed from December 5 to December 30, 2008. Analysis of data was done by using descriptive statistics, chi-square test, t-test and ANCOVA with SPSS program. Results: 1) The groups were significantly correlated with such variables systolic BP(F=4.518, p=0.035) and diastolic BP(F=17.793, p=0.000). 2) The groups with hypertensive were significantly correlated with such variables perceived susceptibility of disease($\chi^2$=25.053, p=0.000), perceived barrier of health behavior($\chi^2$=12.584, p=0.006), drinking($\chi^2$=27.545, p=0.000), diet($\chi^2$=8.645, p=0.013), regular taking medicine($\chi^2$=92.415, p=0.000) and regular measurement of BP($\chi^2$=6.045, p=0.049). 3) The groups with diabetic were significantly correlated with such variables perceived seriousness of disease($\chi^2$=6.128, p=0.047), perceived susceptibility of disease($\chi^2$=8.079, p=0.018), health knowledge and attitude(F=8.418, p=0.006), drinking($\chi^2$=6.276, p=0.043), diet($\chi^2$=7.275, p=0.026), regular taking medicine($\chi^2$=33.083, p=0.000) and regular measurement of glucose($\chi^2$=7.233, p=0.027). Conclusion: The above findings indicate that it is necessary to develop and apply special management programs according to the therapy discontinuity group.

• Toxicological Research
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• 제19권3호
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• pp.227-234
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• 2003

2-Bromopropane (2-BP), a halogenated propane analogue, is a substitute for chlorofluorocarbones (CFCs) which have a great potential to destroy the ozone layer and to warm the earth's environment. The present study was undertaken to evaluate the potential adverse effects of 2-BP on pregnant dams and embryo-fetal development after maternal exposure during the gestational days (GD) 6 through 17 in ICR mice. The test chemical was administered subcutaneously to pregnant mice at dose levels of 0, 313, 625 or 1,250 mg/kg/day. All dams were subjected to caesarean section on GD 18 and their fetuses were examined for external, visceral and skeletal abnormalities. In the 1,250 mg/kg group, maternal toxicity included an increase in the incidence of abnormal clinical signs and a decrease in the maternal body weight, body weight gain, and corrected body weight. Developmental toxicity included a decrease in the fetal body weight, a reduction in the placental weight, an increase in the fetal skeletal variation and ossification delay. There were no adverse effects on either pregnant dams or embryo-fetal development in the 313 and 625 mg/kg groups. These results suggest that a 12-day subcutaneous dose of 2-BP is embryotoxic at a maternally toxic dose (i.e., 1,250 mg/kg/day) in ICR mice. In the present experimental condition, the no-observed-adverse-effect level of 2-BP is considered to be 625 mg/kg/day for dams and embryo-fetuses, respectively.

• 한국산업보건학회지
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• 제8권2호
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• pp.272-288
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• 1998

The purpose of this study was to investigate the acute(4 hrs) and repeated-dose(6 hrs a day, 5 days a week, 8 weeks) toxic effects of 1-bromopropane(1-BP) on Sprague-Dawley (SD) rats which were treated by inhalation. The results were as follows ; 1. The median lethal concentration($LC_{50}$) was estimated 14,374 ppm(confidence limit 95% ; 13,624~15,596 ppm) in acute inhalation. Abnormal clinical signs related to the 1-BP were not observed with the acute inhalation dose. Gross findings of necropsy revealed no evidence of specific toxicity related to the 1-BP. 2. By sub-acute inhalation the body weights of male and female were significantly reduced(p<0.001) by the dose of 1,800 ppm compared with control group, while the relative weights of liver were significantly increased(p<0.001) in both sexes. However there were no significant variation in food consumption, urine biochemistry, hematology and blood biochemistry for the exposed rats compared with the control rats. Abnormal clinical signs and gross findings of necropsy related to the 1-BP were not shown. No toxicologic lesions were observed by the histopathological test.

• 한국동물위생학회지
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• 제28권1호
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• pp.71-79
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• 2005

In this study, a total of 2,119 samples was taken from bovine feces and carcass from March 2002 to December 2003. And those were examined for the presence of enterohemorrhagic E coli O157:H7. The properties of the isolates were characterized for biochemical features, serotypes, virulence genes and antimicrobial susceptibility. Forty five strains($3.7\%$) of E coli O157:H7 were isolated from 1,208 fecal samples and were not detected in carcass using immunomagnetic separation technique and selective media. In multiplex PCR using stx1, stx2, eaeA and hlyA primers, the amplified bands at 180 bp, 255bp, 384bp and 534bp were observed, respectively. In antimicrobial susceptibility test, all isolates were susceptible to amoxicillin/clavulanic acid and cefazolin. The isolates were most resistant to sulfisoxazole($24.4\%$), followed by streptomycin($22.2\%$), tetracycline($20.0\%$). Eight strains($17.8\%$) of 45 isolates showed the multi-resistant patterns with over 3 drugs.

• 한국의류학회지
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• 제40권2호
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• pp.240-257
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• 2016

This study determines the effect of 3D compression pants and Kinesio taping on muscular function of the leg during knee joint flexion and extension. Eight males participated in the experiment, wearing basic pants (BP), Kinesio taping on bare skin (KT), 3D compression pants with (KTP) and without Kinesio taping (CP). The test protocol for isokinetic muscular function was composed of four sets at three angular velocities (60, 180, $240^{\circ}/sec$) using Cybex 660. Peak torque and work per repetition of the lower limbs of eight males were analyzed from the result of Cybex. Agility and power of the subjects were examined from side step and sergeant jump. Peak torque, average power, work per repetition, force decay time of subjects wearing CP and KTP were significantly better than BP or KT, especially at low angular velocity of $60^{\circ}/sec$. The time to generate peak torque of subjects wearing BP was the longest, while the force-decay time of BP was the shortest. The application of Kinesio tape on skin did not increase muscle peak torque, work and power, but did shorten the time to generate peak torque.

• International Journal of Industrial Entomology and Biomaterials
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• 제5권1호
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• pp.85-91
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• 2002

The sequences of the internal transcribed spacers (ITS1 and ITS2) and 5.8S ribosomal DNA gene from five Cordyceps species and one Paecilomyces japonica were determined. The total length of the ITSI, 5.8S and ITS2 regions ranged from 528 to 549 bp. When the C. militaris collected from Korea was used as a standard genotype, the sequence showed 88.4%, 88.6%, 91.1% and 86.8% identity to C. pruinosa, C. sphecocephala, C. scarabaeucika and R japonica, respectively, while the lowest identity was found with C. sinensis (75.4%). Interestingly, C. sinensis was phylogenetically distant from the other Cordyceps species. To test geographic variation, furthermore, sequences of the ITS regions in the 8 samples of C. militaris collected from two localities in Korea and China analyzed and compared with the GenBank-searched sequences from Japan and China. The total length of the ITS regions of C. militaris from Korea, Japan and China was completely identical to each other with 528 bp, and the sequence divergence among three localities in pairwise comparisons ranged from 0.2% (1 bp) to 0.4% (2 bp).

• 원예과학기술지
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• 제17권6호
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• pp.770-772
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• 1999

새로 육성된 품종의 보호를 위한 분자마커를 대상 작물에 전이시키는 체계를 확립하고자 본 실험을 실시하였다. 식물에서는 전혀 존재하지 않는 mouse adenosine deaminase(ADA) gene으로부터 분자마커로 활용 가능한 크기의 DNA 단편을 획득하고 이를 pBI101에 삽입하여 chimeric gene을 만들었다. 분자마커를 포함하는 형질전환된 담배를 획득하기 위해 A. tumefaciens LBA4404를 이용하여 형질전환을 실시하였다. 담배 절편체에서 형질전환된 신초를 얻기 위해 BAP $1.5mg{\cdot}L^{-1}$, kanamycin $50mg{\cdot}L^{-1}$과 cefotaxim $200mg{\cdot}L^{-1}$이 혼용된 MS배지에서 선발하였으며 신초 발생후 kanamycin의 농도를 2배, 4배로 증가시켜 chimeric gene이 완전하게 전이되어 저항성을 가진 8개체를 얻었다. 항생제에 의해 선발된 8개체를 분자마커 primer로 PCR분석하여 분자마커가 식물체의 genome내로의 전이를 확인하였다.