• Title/Summary/Keyword: BP test

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A Major DNA Marker of BM4311 Microsatellite Locus in Hanwoo Chromosome 6 using the Bootstrap BCa Method

  • Lee, Jea-Young;Kim, Mun-Jung;Lee, Young-Won
    • Journal of the Korean Data and Information Science Society
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    • v.15 no.1
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    • pp.41-47
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    • 2004
  • DNA marker 95bp and 100bp are selected as major DNA markers of the BM4311 microsatellite locus in progeny test Hanwoo chromosome 6 linkage map. This document is tried to know whether DNA marker 95bp and 100bp are also major DNA markers in Hanwoo performance valuation in chromosome 6 linkage map. The bootstrap BCa method will be used to calculate confidence interval for DNA markers.

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Extended-Spectrum $\beta$-Lactamase (ESBL) Typing of Klebsiella pneumoniae Isolated from Clinical Specimen in Pusan (부산시내 종합병원의 임상 검체에서 분리된 Extended -Spectrum $\beta$-Lactamase 생성 Klebsiella pneumoniae의 형별 분류)

  • 김윤태;이훈구
    • Korean Journal of Microbiology
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    • v.36 no.3
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    • pp.221-227
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    • 2000
  • This study was performed to investigate the biological characteristics of twenty isolates of extended spectnlm $\beta$-lactamase (ESBL) producing Klebsiellapnezm~onia collected kom the various clinical specimens of three hospitals in Pusan. Isoelectric focusing (IEF) and PCR were used to determine the types of $\beta$-lactamase gene in this study. Twenty isolates of ESBL producing Klebsiellnp~ieun~or~iae could be divided by PCR, such as TEM type (I1 strains), SHV type (8 strains); non TEM non SHV type (1 strain). In the isoelechic focusing test, the PI of TEM type was 5.2-6.0 and that of SHV type was 6.9-7.4. According to the pI value and PCR bands, twenty strains of ESBL Klebsiellapneumoniae were divided into 5 types: TEM type @I 5.2-6.0; 1080 bp on PCR band), TEM + SHV type (pI 5.2-6.0; andpI 7.0-7.4; 1080 bp and 599 bp on PCR band), SHV type (pl7.0-7.4; 599 bp on PCR band), non TEM non SHV type, and otber type (PCR result was SHV type but pI was not detected).

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Feasibility of combinational burnable poison pins for 24-month cycle PWR reload core

  • Dandi, Aiman;Lee, MinJae;Kim, Myung Hyun
    • Nuclear Engineering and Technology
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    • v.52 no.2
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    • pp.238-247
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    • 2020
  • The Burnable Poison (BP) is very important for all Light Water Reactors in order to hold-down the initial excess reactivity and to control power peaking. The use of BP is even more essential as the excess reactivity increases significantly with a longer operation cycle. In this paper a feasibility study was conducted in order to investigate the benefits of a new combinational BP concept designed for 24-month cycle PWR core. The reference designs in this study are based on the two Korean fuel assemblies; 17 × 17 Westinghouse (WH) design and 16 × 16 Combustion Engineering (CE) design. A modification was done on these two designs to extend their cycle length from 18 months into 24 months. DeCART2D-MASTER code system was used to perform assembly and core calculations for both designs. A preliminary test was conducted in order to choose the best BP suitable for 24-month as a representative for single BP concept. The comparison between the results of two concepts (combinational BP concept and single BP concept) showed that the combinational BP concept can replace the single BP concept with better performance on holding down the initial excess reactivity without violating the design limitations.

Flood Stage Forecasting using Kohonen Self-Organizing Map (코호넨 자기조직화함수를 이용한 홍수위 예측)

  • Kim, Seong-Won;Kim, Hyeong-Su
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.1427-1431
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    • 2007
  • In this study, the new methodology which combines Kohonen self-organizing map(KSOM) neural networks model and the conventional neural networks models such as feedforward neural networks model and generalized neural networks model is introduced to forecast flood stage in Nakdong river, Republic of Korea. It is possible to train without output data in KSOM neural networks model. KSOM neural networks model is used to classify the input data before it combines with the conventional neural networks model. Four types of models such as SOM-FFNNM-BP, SOM-GRNNM-GA, FFNNM-BP, and GRNNM-GA are used to train and test performances respectively. From the statistical analysis for training and testing performances, SOM-GRNNM-GA shows the best results compared with the other models such as SOM-FFNNM-BP, FFNNM-BP, and GRNNM-GA and FFNNM-BP shows vice-versa. From this study, we can suggest the new methodology to forecast flood stage and construct flood warning system in river basin.

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Flood Stage Forecasting using Class Segregation Method of Time Series Data (시계열자료의 계층분리기법을 이용한 하천유역의 홍수위 예측)

  • Kim, Sung-Weon
    • 한국방재학회:학술대회논문집
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    • 2008.02a
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    • pp.669-673
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    • 2008
  • In this study, the new methodology which combines Kohonen self-organizing map(KSOM) neural networks model and the conventional neural networks models such as feedforward neural networks model and generalized neural networks model is introduced to forecast flood stage in Nakdong river, Republic of Korea. It is possible to train without output data in KSOM neural networks model. KSOM neural networks model is used to classify the input data before it combines with the conventional neural networks model. Four types of models such as SOM-FFNNM-BP, SOM-GRNNM-GA, FFNNM-BP, and GRNNM-GA are used to train and test performances respectively. From the statistical analysis for training and testing performances, SOM-GRNNM-GA shows the best results compared with the other models such as SOM-FFNNM-BP, FFNNM-BP, and GRNNM-GA and FFNNM-BP shows vice-versa. From this study, we can suggest the new methodology to forecast flood stage and construct flood warning system in river basin.

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Development and Validation of a Multidimensional Measure of Positive Body Image

  • Lee, Minsun;Lee, Hyun-Hwa
    • Journal of the Korean Society of Clothing and Textiles
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    • v.46 no.4
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    • pp.704-722
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    • 2022
  • Current studies validate the Body Positive Scale (BP Scale) as a self-assessment instrument that captures four dimensions of the positive body image construct. We developed and evaluated a 17-item BP Scale using two focus group interviews and four independent samples (n = 1,379) of Korean women who completed online survey questionnaires. We generated an initial pool of items via literature review, content validation with experts, and focus group interviews, subsequently refining the items through exploratory analysis (Study 1). We confirmed the BP Scale's underlying dimensions with young Korean female samples (Study 2, Study 4) and with a community sample (Study 3). We also examined the construct validity, internal consistency, and test-retest reliability over a six-week interval. Overall, the results supported that the four-factor BP Scale demonstrates adequate validity and reliability in measuring positive body image among Korean women. The BP Scale provides a method for researchers and practitioners to understand and assess individuals' positive body image in a multifaceted manner.

Clinical significance of drug cessation on medication-related osteonecrosis of the jaw in patients with osteoporosis

  • Kezia Rachellea Mustakim;Mi Young Eo;Ju Young Lee;Mi Hyun Seo;Soung Min Kim
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.49 no.2
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    • pp.75-85
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    • 2023
  • Objectives: Suspending bisphosphonates (BPs) to reduce the risk and severity of medication-related osteonecrosis of the jaw (MRONJ) remains controversial. In this study, we quantitatively evaluated the clinical significance of BP suspension before surgery in osteoporosis patients with MRONJ. Materials and Methods: We analyzed 24 osteoporosis patients with MRONJ who were treated from 2012 to 2020 at Seoul National University Dental Hospital and compared the treatment outcomes of those who suspended BPs with those who did not. The number of surgical interventions, follow-up panoramic radiographs for relative bone density measurement, and laboratory blood tests including white blood cells, erythrocyte sedimentation rate, absolute neutrophil count, hemoglobin, hematocrit, and alkaline phosphatase were analyzed. ANOVA, Student's t-test, and Mann-Whitney U tests were used to compare results. Fisher's exact test was used to discover the association between treatment outcome and BP suspension, and Pearson's correlation test was used to measure the statistical relationship between the changes in serum inflammatory markers. Results: The number of interventions was significantly higher in the non-drug suspension group due to recurrence (P<0.05). The relative bone density in patients who suspended BPs was significantly different over time (P<0.05), with the highest density at one-year follow-up. Fisher's exact test shows an association between successful treatment outcomes and BP suspension. The alkaline phosphatase and erythrocyte sedimentation rate levels decreased significantly in the BP-suspended group, and a positive correlation was found between these elevated markers. Conclusion: A significant increase in bone density throughout follow-up and a lower number of interventions were found in the BP suspension group compared to the non-drug suspension group. Also, BP suspension decreased inflammatory markers in the serum after surgery, resulting in good treatment outcomes. BP suspension is a prognostic factor for MRONJ and should be implemented before surgery.

Validation study of the Dinamap ProCare 200 upper arm blood pressure monitor in children and adolescents

  • Lee, Chong-Guk;Park, Hyang-Mi;Shin, Hye-Jung;Moon, Jin-Soo;Hong, Young-Mi;Kim, Nam-Soo;Ha, Il-Soo;Chang, Myeong-Jin;Oh, Kyeong-Won
    • Clinical and Experimental Pediatrics
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    • v.54 no.11
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    • pp.463-469
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    • 2011
  • Purpose: To validate the Dinamap ProCare 200 blood pressure (BP) monitor against a mercury sphygmomanometer in children 7 to 18 years old in accordance with the 2010 International Protocol of European Society of Hypertension (ESH-IP2) and the British Hypertension Society (BHS) protocol. Methods: Forty-five children were recruited for the study. A validation procedure was performed following the protocol based on the ESH-IP2 and BHS protocols for children and adolescents. Each subject underwent 7 sequential BP measurements alternatively with a mercury sphygmomanometer and the test device by trained nurses. The results were analyzed according to the validation criteria of ESH-IP2. Results: The mean (${\pm}SD$) difference in the absolute BP values between test device and mercury sphygmomanometer readings was $1.85{\pm}1.65$ mmHg for systolic BP (SBP) and $4.41{\pm}3.53$ mmHg for diastolic BP (DBP). These results fulfilled the Association for the Advancement of Medical Instrumentation criterion of a mean${\pm}$SD below $5{\pm}8$ mmHg for both SBP and DBP. The percentages of test device-observer mercury sphygmomanometer BP differences within 5, 10, and 15 mmHg were 96%, 100%, and 100% for SBP, and 69%, 92%, and 100% for DBP, respectively, in the part 1 analysis; both SBP and DBP passed the part 1 criteria. In the part 2 analysis, SBP passed the criteria but DBP failed. Conclusion: Although the Dinamap ProCare 200 BP monitor failed an adapted ESH-IP2, SBP passed. When comparing BP readings measured by oscillometers and mercury sphygmomanometers, one has to consider the differences between them, particularly in DBP, because DBP can be underestimated.

A Study of ECG Based Cardiac Diseases Diagnoses (심전도 신호를 이용한 심장 질환 진단에 관한 연구)

  • Kim, Hyun-Dong;Yoon, Jae-Bok;Kim, Hyun-Dong;Kim, Tae-Seon
    • Proceedings of the KIEE Conference
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    • 2004.11c
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    • pp.328-330
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    • 2004
  • In this paper, ECG based cardiac disease diagnosis models are developed. Conventionally, ECG monitoring equipments can only measure and store ECG signals and they always require medical doctor's diagnosis actions which are not desirable for continuous ambulatory monitoring and diagnosis healthcare systems. In this paper, two kinds of neural based self cardiac disease diagnosis engines are developed and tested for four kinds of diseases, sinus bradycardia, sinus tachycardia, left bundle branch block and right bundle branch block. For diagnosis engines, error backpropagation neural network (BP) and probabilistic neural network (PNN) were applied. Five signal features including heart rate, QRS interval, PR interval, QT interval, and T wave types were selected for diagnosis characteristics. To show the validity of proposed diagnosis engine, MIT-BIH database were used to test. Test results showed that BP based diagnosis engine has 71% of diagnosis accuracy which is superior to accuracy of PNN based diagnosis engine. However, PNN based diagnosis engine showed superior diagnosis accuracy for complex-disease diagnoses than BP based diagnosis engine.

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Bootstrapping and DNA Marker Mining of ILSTS098 Microsatellite Locus in Hanwoo Chromosome 2

  • Lee, Jea-Young;Kwon, Jae-Chul
    • Communications for Statistical Applications and Methods
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    • v.13 no.3
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    • pp.525-535
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    • 2006
  • We describe tests for detecting and locating quantitative traits loci (QTL) for traits in Hanwoo. Lod scores and a permutation test have been described. From results of a permutation test to detect QTL, we select major DNA markers of ILSTS098 microsatellite locus in Hanwoo chromosome 2 for further analysis. K-means clustering analysis applied to four traits and eight DNA markers in ILSTS098 resulted in three cluster groups. We conclude that the major DNA markers of BMS1167 microsatellite locus in Hanwoo chromosome 2 are markers 105bp, 113bp and 115bp. Finally, bootstrap testing method has been adapted to calculate confidence intervals and for finding major DNA Markers.