• 제목/요약/키워드: BOLD effect

검색결과 44건 처리시간 0.024초

Detection of Neuronal Activity by Motion Encoding Gradients: A Snail Ganglia Study

  • Park, Tae-S.;Park, Ji-Ho;Cho, Min-H.;Lee, Soo-Y.
    • 대한의용생체공학회:의공학회지
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    • 제28권1호
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    • pp.24-28
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    • 2007
  • Presuming that firing neurons have motions inside the MRI magnet due to the interaction between the neuronal magnetic field and the main magnetic field, we applied motion encoding gradients to dissected snail ganglia to observe faster responding MRI signal than the BOLD signal. To activate the snail ganglia in synchronization with the MRI pulse sequence, we used electrical stimulation with the frequency of 30 Hz and the pulse width of 2s. To observe the fast responding signal, we used the volume selected MRI sequence. The magnetic resonance signal intensity, measured with 8 ms long motion encoding gradient with a 20mT/m gradient strength, decreased about $3.46{\pm}1.48%$ when the ganglia were activated by the electrical stimulation.

비비엔 웨스트우드(Vivienne Westwood)의 작품세계 연구 (A Study on Vivienne Westwood Design)

  • 방수란
    • 한국가정과학회지
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    • 제2권1호
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    • pp.129-141
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    • 1999
  • The purpose of this study is to investigate the effect of historical costume style and painting on Vivienne Westwood design. For this purpose, the costume style after 16C and the rococo painting of 18C are researched. And through Westwood's recent designs, the external form and internal symbol are compared. The results of this study were as follows : 1. From Renaissance, Rococo, Crinoline, Bustle, S style were showed on Westwood design. 2. In external method, historical costume styles were expressed by silhouette, detail, costume item, textile and various cuttings. 3. In the case of painting, it focused on Rococo painting of 18C. Costumes in painting were realized or painting itself were used for textile. 4. Most of her design was cut in the round rather than in the flat, bold cutting and slash were employed. 5. These works are symbolizing the harmony of tradition and future, at the same time through the transformation of orthodox style, containing ridicule to the authority and a challenge to society as well as sex. These results let us know that Westwood is versatile to transform the history and harmonize the tradition and 20C Fashion successfully. (Korean J Human Ecology 2(1):129∼141, 1999)

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Evaluation of the effect of testosterone supplementation on the brain activity associated with sexual arousal in hypogonadal patients: Functional MRI

  • 은성종;서정진;정광우;강형근;김형중;이진명
    • 대한자기공명의과학회:학술대회논문집
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    • 대한자기공명의과학회 2002년도 제7차 학술대회 초록집
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    • pp.112-112
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    • 2002
  • Purpose: The Purpose of this study was to evaluate the quantitative variation of brain activity evoked by visual sexual stimulation before and after testosterone supplementation in hypogonadal patients by using BOLD functional MR imaging.

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Influence of Extracellular Products from Haematococcus pluvialis on Growth and Bacteriocin Production by Three Species of Lactobacillus

  • Kim Jeong-Dong;Lee Choul-Gyun
    • Journal of Microbiology and Biotechnology
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    • 제16권6호
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    • pp.849-854
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    • 2006
  • The effects of Haematococcus pluvialis extracellular products on microbial growth and bacteriocin production were investigated to improve bacteriocin synthesis during the growth cycle of Lactobacilli. Lactobacillus pentosus KJ-108, L. plantarum KJ-10311, and L. sakei KJ-2008 were cultured in MRS and enriched medium (ERM) with or without supplement of the extracellular products obtained from a late exponential phase culture of Haematococcus pluvialis in modified Bold's basal medium (MBBM). In both MRS and ERM, the extracellular products strongly enhanced the growth as well as the bacteriocin production of all the lactic acid bacteria tested. The enhancing effect was observed in ERM with pH adjusted at 5 and 6. In addition, some difference in growth effects with the extracellular products of H. pluvialis was observed between pH 5 and 6 in ERM, but no effect was observed in the minimal medium. The final biomass and the final concentration of bacteriocin activity were associated with the cell growth that was promoted by the extracellular products of H. pluvialis, and the enhanced cell growth of the three lactic acid bacterial strains induced the increase of the specific bacteriocin production. Therefore, bacteriocin production and activity were influenced by the addition of the extracellular products of H. pluvialis in the culture medium.

The Effect of the CEO's Entrepreneurship on Corporate Performance in the Restaurant Industry

  • Jun-Young Lee;Sung-Ho Bang;Ki-Hwan Ryu
    • International journal of advanced smart convergence
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    • 제12권3호
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    • pp.168-174
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    • 2023
  • The purpose of this paper is to analyze entrepreneurship and to find out the impact of CEOs in the restaurant industry on corporate performance when they have entrepreneurship. Entrepreneurs need entrepreneurship to take risks and jump into the market to generate profits. Entrepreneurship is not limited to the abilities or resources held, but it is not limited to the ability or resources held, and entrepreneurship to act means the spirit to take uncertainty and preempt opportunities through innovative activities [1]. In this study, the CEO's entrepreneurship was set as an independent variable and corporate performance as a dependent variable. By applying and analyzing how the CEO's entrepreneurship affects corporate performance in the restaurant industry, the importance of entrepreneurship in the restaurant industry and the impact relationship on corporate performance are analyzed. To this end, 100 CEOs working in the restaurant industry will be surveyed using the Likert 5-point scale[2]. And an empirical analysis will be conducted through the SPSS program[3]. Entrepreneurship is a spirit that can take risks and seize opportunities through bold challenges to generate profits. Therefore, it has been confirmed that it affects corporate performance as a key factor for improving corporate performance, and from related studies, the entrepreneurship of the CEO of the restaurant industry is expected to have a positive (+) effect on corporate performance.

HCl/에탄올로 유발된 급성 위염에서 Artemisia frigida Willd의 위장 보호 효과 (Gastroprotective Effect of Artemisia frigida Willd in HCl/Ethanol-induced Acute Gastritis)

  • 오민혁;이세희;박해진;신미래;;노성수
    • 생약학회지
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    • 제52권4호
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    • pp.242-250
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    • 2021
  • Artemisia frigida Willd (AW, Fringed sagewort), which is widespread in Mongolia, is a well-known medicinal plant as a member of the Compositae family. This study aims to explore the gastroprotective effect of water extract of AW on 150 mM HCl/60% ethanol-induced acute gastritis in 5 week old male ICR mice. Total polyphenols, total flavonoid contents, and anti-oxidant activity in vitro in AW were evaluated. First, the gross area of gastric mucosal damage was measured. Then western blot analysis was conducted to determine the possible mechanisms of action underlying the effects of AW. AW administration decreased gastric mucosal damage. Moreover, the group with AW treatment effectively inhibited nicotinamide adenine dinucleotide phosphate (NADPH) oxidase expression associated with oxidative stress. AW treatment enhanced an anti-oxidant effect through the increase of anti-oxidant proteins. Besides, the increased expressions of inflammatory cytokines induced by nuclear factor-kappa B (NF-κB) activation are alleviated through AW treatment. Taken together, AW exerted a gastroprotective effect against gastric mucosal damage. These results indicate that AW could have the potential used as a natural therapeutic drug for the treatment of acute gastritis.

소음 감쇠기를 이용한 청각의 뇌기능 자기공명영상 (A Study of the Effect of Acoustic Noise Attenuator on Auditory Functional MRI)

  • 김상환;김인성;이재준;박지애;이영주;여종록;배성진;이상흔;장용민
    • Investigative Magnetic Resonance Imaging
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    • 제9권2호
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    • pp.134-139
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    • 2005
  • 목적 : 청각의 뇌기능 영상 검사 시 소음 감쇠기의 유용성을 알아보고자 하였다. 대상 및 방법 : 소음 감쇠기는 실리콘 이어폰, 귀마개 그리고 마스크로 구성하였다. 마스크와 귀마개는 방음효과가 크다고 알려져 있는 부드러운 재질의 폴리우레탄 시트와 폴리우레탄 폼을 사용하여 제작하였다. 500 Hz의 순음 자극에 대한 청각의 뇌기능 자기공명영상 실험은 4명의 지원자를 대상으로 다음의 세가지 경우로 구별하여 시행하였다: 첫째, 마스크와 귀마개, 이어폰을 모두 착용한 경우, 둘째, 귀마개와 이어폰만을 착용한 경우 그리고 마지막으로 소음 감쇠기를 착용하지 않은 경우 이다. 데이터 획득을 위하여 고성능 경사자계 시스템이 갖추어진 1.5 T 자기공명영상장치에서 BOLD 자기공명 영상기법을 사용하였다. 영상 데이터는 SPM 99 분석프로그램을 이용하여 분석하여 활성화 지도를 획득하였다. 결과 : 소음감쇠기의 모든 구성요소를 사용한 경우 활성화는 주로 일차 청각중추에서만 집중되어 나타나는 결과를 얻었다. 귀마개와 이어폰만을 착용했을 때는 청각의 뇌 활성화 영역이 일차 청각중추와 이차 청각 영역에 분산되어 나타는 결과를 얻었으며 마지막으로 소음감쇠기를 사용하지 않은 경우 청각영역이 오른쪽의 일부만이 활성화 되었다. 결론 : 마스크, 귀마개, 이어폰으로 구성된 소음 감쇠기는 청각의 뇌기능 영상 검사 시 매우 유용할 것으로 기대된다.

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음릉천(陰陵泉)(Sp9)의 전침자극(電鍼刺戟)이 functional MRI상 뇌활성(腦活性) 변화(變化)에 미치는 영향(影響) (A fMRI study on the cerebral activity induced by Electro-acupuncture on Sp9(Yinlingquan))

  • 김정호;이현;임윤경;홍권의;이병렬;김연진
    • Journal of Acupuncture Research
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    • 제20권4호
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    • pp.114-133
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    • 2003
  • Objective : The meridian theory in oriental medicine explains that Sp9(Yinlingquan) has been considered very important for gynecological disorders, spleen and stomach disorders, and water metabolic disorders. Functional MRI is the best method of showing the evidences of the effect of the Electro-acupuncture treatment through scientific methods. On this supposition, Electro-acupuncture stimulation on Sp9(Yinlingquan) was carried out on six healthy volunteers, using the gradient echo sequence with the 3.0T whole-body MRI system(ISOL). Methods : Electro-acupuncture stimulation on Sp9(Yinlingquan), the experiment was carried out on six healthy volunteers, using the gradient echo sequence with the 3.0T whole-body MRI system(ISOL). After the needle insertion on right Sp9(Yinlingquan), 2Hz of electric stimulation was given for 30 seconds, repeated five times, with 30 seconds' intervals. The Image analysis including motion correction, talairach transformation, and smoothing was done using SPM99. Results : The electro-acupuncture stimulation on Sp9(Yinlingquan) activates Brodmann Area 13, 19, 22, 39, 40, 47 which may be the central pathways of the electro-acupuncture stimulation on Sp9(Yinlingquan). We also hypothesize that those brain areas may be directly or indirectly related with the mechanism of the effect of electro-acupuncture stimulation on Sp9(Yinlingquan).

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풍륭(豊隆)(St40) 전침(電鍼)이 뇌활성(腦活性) 변화(變化)에 미치는 영향(影響) (fMRI를 이용한 연구) (fMRI study on the cerebral activity induced by Electro-acupuncture on Fenglong(St40))

  • 배은정;홍권의;이현;이병렬;임윤경;김연진
    • Journal of Acupuncture Research
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    • 제20권5호
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    • pp.208-226
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    • 2003
  • Objective : Recently many studies have showed the evidence of the effect of the acupuncture treatment through scientific methods. One of these methods is functional MRI. We performed electro-acupuncture on St40 and observed the change of brain activation using fMRI. Methods : To see the effects of electro-acupuncture stimulation on Fenglong(St40), the experiment was carried out on six healthy volunteers, using the gradient echo sequence with 3.0T whole-body MRI system(ISOL). after the needle insertion on right Fenglong(St40), 2 Hz of electric stimulation was given for 30 seconds, repeated five times, with 30 seconds' intervals. Results & Conclussion : Electro-acupuncture stimulation on Fenglong(St40) activated Brodmann's Areas of 2, 3, 4, 6, 9, 10, 13, 18, 22, 30, 40, 42, 43 which may be the central pathways of electro-acupuncture stimulation on Fenglong(St40).

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유사중복사업 통폐합 정책에 대한 기대효과와 태도 -소득계층 간의 차이를 중심으로- (Citizens' Expectations from Government and Policy Attitude with Regard to Reducing Overlap and Duplicating among Government Programs -Does an Income Class Difference Matter?-)

  • 이재완
    • 한국콘텐츠학회논문지
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    • 제17권7호
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    • pp.133-143
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    • 2017
  • 본 연구는 정부가 추진하고 있는 유사중복사업 통폐합 정책에 대한 기대효과가 그 정책태도에 미치는 영향을 분석하고, 나아가 소득계층 간에 그 영향에 차이가 있는지를 실증분석하는 것이다. 그 분석결과, 기대효과인 예산낭비 축소는 정책태도에 유의미한 긍정적인 영향을 미쳤으나, 업무효율성 향상은 유의미하지 않았다. 소득계층의 경우 유사중복사업 통폐합 정책에 대해 상층보다 하층이, 하층보다 중층이 더 부정적이었다. 조절효과의 경우 소득계층이 예산낭비 축소와 정책태도 간의 양(+)의 관계를 약화시켰으며, 업무효율성 향상과 정책태도 간의 음(-)의 관계를 약화시켰다. 이는 유사중복사업에서 큰 비중을 차지하고 있는 사회보장 프로그램의 수혜주체와 비용부담주체가 다르기 때문이다. 본 연구의 정책적 시사점은 유사중복사업 통폐합 정책의 지지를 확보하기 위해서는 이 정책이 특정 계층에게만 희생과 부담을 강요하는 것은 아니며, 국가 전체의 재정효율성 제고를 통해 더 많은 계층이 혜택을 받을 수 있다는 점을 적극 홍보할 필요가 있다는 것이다.