• 식물조직배양학회지
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• 제24권1호
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• pp.1-35
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• 1997

Fertilized egg, by successive cell divisions, differentiates into different tissues and organs with various structures and functions. Different cells and tissues contain different proteins, products of selective gene expression. Not all the genes in any genomes are equally active, temporal and spatial gene expression being the general rule. Present paper attempts to review the tanscriptional mechanisms or the initiations of transcription from several angles. In some of the organisms the genes in the process of transcription or the genes in the inactive state can be seen under the light microscope. Some bands of Drosophila polytene chromosomes may exhibit a swollen or puff appearance under certain conditions. A puff, unfolded or decondensed form of chromomere, represents sets of intense transcriptional activity or RNA synthesis. The heterochromatic X chromosome whose genes remain inactive in the female mammals can be visualized as a dark staining structure called Barr body, Configuration of chromatin differs between transcribed and nontranscribed chromatin. Modification to the chromatin facilitates RNA synthesis. The movement of large polymerase molecule along the DNA would probably be facilitated if some modifications of the chromatin configuration is effected. Methylation of cytosines in CG sequences is associated with inactive genes. Methylation can play a role in determination of mammalian cells during embryogenesis. Demethylation is necessary for the gene to be expressed during development A histone modification that is also known to be correlated with transcriptional capacity of chromatin is acetylation of the lysine residues of the core histones. Chromatin containing a high level of histone acetylation is very sensitive to DNase 1. For the transcription to occur TBP must first bind to the TATA box. Another TF, TF IIB, then binds to the promoter-TBP complex, facilitating the access of RNA polymerase to the transcription initiation site. As recently as eight years ago researchers assumed that histones were irrelevant to the regulation of gene expression. Histones combine with the DNA to form nucleosome of the chromatin. Histones are vital participant in gene regulation. Histone and basal factors compete for access to TATA box. When DNA is exposed to basal factors before histones are introduced, the basal factors assemble on TATA boxes preventing the access of histones, allowing transcription to occur, for transcription to begin, activator protein at the upstream activation sequence or enhancer must interact with the tail of histone H4 at TATA box and cause the histone role particle to dissociate from the TATA box leading to partial breakup of the histone core particle and allowing the basal factors to bind to the TATA box. New concept of genomic flux in contrast to the old concept of static genome has been developed based on the powerful new molecular techniques. Genomic changes such as repetitive DNAs and transposable elements, it is assumed but not yet proved, may affect some of the developmental patterns that characterize particular cells, tissues, organs, and organisms. In the last decade or so remarkable achievement have been made in the researches of the structures and functions of TFs and the specific target sequences located in promoters or enhancers where these TFs bind. TFs have independent domains that bind DNA and that activate transcription. DNA binding domain of TFs serves to bring the protein into the right location. There are many types of DNA binding domains. Common types of motifs can be found that are responsible for binding to DNA. The motifs are usually quite short and comprise only a small part of the protein structure. Steroid receptors have domains for hormone binding, DNA binding, and activating transcription. The zinc finger motif comprises a DNA binding domain. Leucine zipper consist of a stretch of amino acids with a leucine residue in every seventh position Two proteins form a dimer because they interact by means of leucine zippers on similar α-helical domain. This positions their DNA binding basic domains for interaction with the two halves of a DNA sequence with dyad symmetry of TGACTCA, ACTGAGT.

• Radiation Oncology Journal
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• 제10권2호
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• pp.137-145
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• 1992

전산화단층촬영에 근거를 둔 3차원선량계산은 소형의 뇌종양에 대한 방사선수술에 있어서 가장 기본이 된다. 본 연구의 방사선수술 프로그램은 전산화단층촬영을 통해 표적 위치, 크기와 모양을 3차원공간에서 결정하고 최적조사면적을 구할 수 있었다. 방사선수술의 선량은 선형가속기의 6메가볼트 고에너지 광자선을 이중 비공면의 회전조사를 가상두부에 실시하여 계산된 3차원적 선량분포와 필름선량계의 실측선량을 비교한 바 거의 일치됨을 확인하였다. 본 연구의 방사선수술에서 $80\%$에서 $50\%$까지 선량곡선의 기울기는 전회전각이 1120도 일때 10 mm 조사면적에서 약 $16.7\%$/mm 였고 30 mm 에서 는 $13.0\%$/mm를 보였다. 또한 표적 주위의 선량분포는 표적내 최대선량값이 $90\%$ 에서 $50\%$ 까지 선량분포의 최대폭은 직경 10 mm조사면에서 2.3 mm를 나타내었으며, $90\%$에서 $20\%$까지의 거리는 5.6 mm를 나타내었으며, 30 mm직경의 조사면에서는 각각 3.5 mm와 9.8 mm를 보였다. 이러한 선량분포의 급격한 기울기는 방사선수술시 표적주위의 치명부위의 손상을 최소화하기 위한 선량최적화 작업에 지침이 될 것으로 생각되며, 또한 방사선수술방법의 차이에 따라 비교자료가 될 수 있을 것으로 생각된다.

• Archives of Plastic Surgery
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• 제38권6호
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• pp.836-844
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• 2011

Purpose: Hands are the chief organs for physically manipulating the environment, using anywhere from the roughest motor skills to the finest, and since the fingertips contain some of the densest areas of nerve endings on the human body, they are continuously used organ with complex functions, and therefore, often gets injured. To prevent any functional loss, a detailed anatomical knowledge is required to have a perfect surgical treatment. Also it is necessary to have a thorough understanding of arrangements of the human extensor tendons and intertendinous connections when tenoplasty or tendon transfer is required. We performed a study of the arrangements of the human extensor tendons and the configuration of the intertendinous connections over the dorsum of the wrist and hand. Methods: A total of 58 hands from Korean cadavers were dissected. The arrangements of extensor indicis proprius, extensor digitorum communis, and extensor digiti minimi tendons and intertendinous connections were studied. Results: The most common distribution patterns of the extensor tendons of the fingers were as follows: a single extensor indicis proprius (EIP) tendon which inserted ulnar to the extensor digitorum-index (EDC-index); a single EDC-index; a single EDC-middle; a double EDC-ring; an absent EDC-little; a double extensor digiti minimi (EDM), a single EDC-index (98.3%), a single EDC-middle (62%), a double EDC-ring (50%), and an absent (65.5%) or a single (32.8%) EDC-little. A double (70.6%) EDM tendons were seen. Intertendinous connections were classified into 3 types: type 1 with thin filamentous type, type 2 with a thick filamentous type, and type 3 with a tendinous type subdivided to r shaped 3r type and y shaped 3y type. The most common patterns were type 1 in the 2nd intermetacarpal space, type 2 in the 3rd intermetacarpal space, and type 3r in the 4th intermetacarpal space. And in the present study, we observed one case of the extensor digitorum brevis manus (EDBM) on the boht side. Conclusion: A knowledge of both the usual and possible variations of the extensor tendon and the intertendinous connection is useful in the identification and repair of these structures.

• 융합보안논문지
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• 제19권5호
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• pp.85-90
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• 2019

본 연구에서는 장애인의 신체활동량 증가를 위해 다양한 디바이스를 적용한 운동중재 동향을 분석하고, 특히 인구고령화로 인한 장애인 노년층 증가에 따른 시대적 니즈에 부합하는 융합형 디바이스 활용 운동중재를 제안하고자 하였다. 장애인에게 적용 가능한 융합형 디바이스 활용 운동중재는 첫째, 가상현실 기반 게이미피케이션을 이용한 운동중재방식, 둘째, 밴드, 시계 등과 같은 착용형 또는 신체부착형의 웨어러블 디바이스 기반 운동중재의 두 가지 유형으로 구분될 수 있다. 장애노인들에게 즐거움과 환경적 제한의 최소화, 개별화가 용이한 융합형 디바이스를 활용한 운동중재를 위해서는 편리한 조작과 간편한 운영규칙, 손쉬운 장치 설치 및 착용 방식, 미숙한 디바이스 활용능력을 보완해줄 수 있는 지도자와 같은 구성요건이 필요하며, 인지능력과 신체적 기능의 현저한 저하를 경험하게 되는 장애인 노년층의 일상생활수행능력 유지 및 향상을 위해서는 일상생활에서 친숙하게 경험할 수 있으면서도 흥미를 유발할 수 있는, 경험이 가능한 신체활동 게임이나 신체활동량 증가를 위한 다양한 디바이스의 활용이 필요하며, 이는 장애를 가진 노인의 긍정적인 신체활동 변화를 가져올 것으로 기대된다.

• 대한토목학회논문집
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• 제10권3호
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• pp.29-38
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• 1990

본(本) 연구(硏究)에서는 종래(從來)의 일반적(一般的)인 비선형(非線型) 해석(解析) 방법(方法)인 Lagrangian방법(方法)을 개선(改善)한 새로운 Pseudo Lagrangian방법(方法)에 의한 기하학적(幾何學的) 선형(非線型) 보요소(要素)의 정식화(Formulation) 과정을 제시(提示)하고 예제해석(例題解析)을 통한 대변형(大變形) 해석결과(解析結果)를 고찰(考察)하여 Pseudo Lagrangian방법(方法)에 의한 보요소(要素)의 대변형(大變形) 해석(解析)의 타당성(妥當性)과 정확도(正確度)를 검증(檢證)하였다. Pseudo Lagrangian방법(方法)에서는 변형전(變形前) 또는 변형후(變形後)의 상태(狀態)를 기준(基準)로 변형(變形)을 나타내는 Total Lagrangian방법(方法)과는 달리 어떠한 물리적(物理的)인 의미(意味)가 없는 임의(任意)의 Pseudo(가상(假想))변형상태(變形狀態)를 기준(基準)으로 변형(變形)을 나타낸다. 유한요소법(有限要素法)에 의한 비선형(非線形) 해석시(解析時) 일반적(一般的)인 Lagrangian방법(方法)은 각(各) 구조요소(構造要素)에 대한 유한요소(有限要素) Mapping과 변형(變形) Mapping을 따로 수행(遂行)하여야 하는데 비하여 Pseudo Lagrangian방법(方法)에서는 한번의 직접적(直接的) Mapping으로 구조요소(構造要素)의 변형상태(變形狀態)를 나타낸다. 예제분석(例題分析) 결과(結果)는 이 PLF방법(方法)에 의한 비선형(非線型) 정식화가 종래(從來)의 Lagrangian방법(方法)보다 적용성(適用性)이 양호(良好)하며 유도과정(誘導過程)이 간편(簡便)함을 보여주고 있으며 PLF방법(方法)에 의한 보요소(要素)의 비선형(非線型) 해석(解析)이 매우 정확(正確)한 결과(結果)를 나타내고 있음을 입증(立證)하고

• Applied Microscopy
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• 제39권3호
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• pp.267-276
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• 2009

주사전자현미경을 이용하여 한국산 긴가락박쥐(Miniopterus schreibersi fuliginosus)와 검은집박쥐(Pipistrellus savii)의 혀유두의 형태를 관찰하였다. 본 연구에서 두 종 모두 세 가지의 혀유두, 즉, 실유두, 버섯유두 그리고 성곽유두가 관찰되었다. 실유두는 다시 두 종류로 세분화되어졌으며, 침상의 돌기물을 갖는 유형1은 혀의 전반부의 1/2 지점까지 분포하며, 유형2는 밋밋하고 두꺼운 돌기물을 갖고 있으며 혀의 후반부의 1/2에 분포한다. 두 종 모두 35~45개의 버섯유두가 혀의 표면에서 관찰된다. 이들 버섯유두는 혀의 측면과 혀의 전반과 후반부의 끝 쪽에서 나타난다. 두 종의 버섯유두는 각각 두 개 혹은 세 개의 매우 큰 유두로 혀의 후반부 중앙에 일직선으로 배열되어 있다. 두 개의 성곽유두는 혀의 후반부 끝쪽 가까이에 분포하고 있다. 이들 성곽유두는 크고 둥글며 각각은 두 층의 pad를 갖고 있다. 긴가락박쥐와 검은집박쥐의 혀유두의 전체적인 형태는 다른 익수류와 유사하였다. 그럼에도 불구하고, 두 종 사이에 드물지만 주목할 만한 차이점이 실유두와 버섯유두에서 나타났다. 검은집박쥐와는 달리 긴가락박쥐의 유형2의 실유두는 두 개 혹은 세 개의 돌기를 가지고 있었다. 혀의 후반부 중앙에 위치하고 있는 큰 버섯유두의 경우, 긴가락박쥐에서는 3개, 검은집박쥐에서는 단지 2개만 관찰되었다.

• 한국실내디자인학회논문집
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• 제18권1호
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• pp.43-53
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• 2009

This study is to investigate the utilization of Indoor Proscenium Stage Zone Lighting method in the dancing performance. In other words, it is about how we can utilize the principle of zone lighting in dancing performance, a kind of stage art. Stage lights give lights on the stage. Therefore they play big and important roles in dancing performances. Lightings make big influence on the overall atvosphere and situations of the dancing work but most of dancers do not perceive their importance and furthermore they don't know about the lightings very well. To let them know about stage lightings better, we studied lightings form the perspective of the dancers who face the lightings without great knowledge thresh the articles and literature related general lightings and lighting design, books related to stage lightings and dancing lightings, previous studies and academic articles. The most important part of this study is to understand and utilize the principle of zone lightiing. Zone lighting is generally called as cross lighting, which means single light from the crossed two lights. When looking into the principle of the zone lighting of the Indoor Proscenium Stage, it means 45 degree lighting from both sides of the top form the point of the dancer When more than two lights are used, the angle of the light should be $90^{\circ}$or 120. It is the principle of the lighting technology showing the face and body of the dancers ing three dimension. Applying for the principle of this zone lighting to the dancing performance of Indoor Proscenium Stage, the lighting methods and the usage of the lightings were studied. As shown above, the role of the lighting is very important in dancing configuration. We hope that the perception on the dancing lighting will be changed and studies on the dancing lightings. By understanding and applying more principles of lighting, we will make efforts to make better dancing performance and dancing conporsers and dancers shall make more efforts and studies on lighting for better works. Through such efforts, we can have more experts and professionals In dancing lighting field and they will help us to describe and express the intention of the dancing work better as dancing artists. We hope that there will be better quality performances through more and diversified studies in this field.

• 비교문화연구
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• 제38권
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• pp.29-63
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• 2015

This paper attempts to re-read Tennessee William's A Streetcar Named Desire from a non-Aristotelian perspective, particularly focusing on the audience performativity. In Chapter 6 of the Poetics, Aristotle says that tragedy has a final purpose or end (telos) and that is to inspire a catharsis (literally "purification") of pity and fear by means of representation and to give pleasure from experiencing their relief. However, a dramatic theoretician Augusto Boal argues that Aristotelian catharsis is not to get rid of pity and fear through their vehement discharge; rather, the basic function of catharsis is the purging of antisocial elements from the social body and the restoration of order because catharsis occurs when the spectator, terrified by the spectacle of the catastrophe, is purified of his "hamartia" which looks similar to the tragic flaw of the hero in the play. Thus, Boal asserts that Aristotle's coercive system of tragedy manipulates the emotions of the passive spectator. By contrast, in non-Aristotelian aesthetics, tragedy functions not as legitimation for a particular political configuration but as the performance of ethical acts-through which all the participants, including not only the actors but also the audience, communicate more actively about practical problems and actively work in order to make sense of themselves, others, and society. Here, the audience is required to restore and reinforce his/her capacity to think and to act; thus, an unquestioning, passive, indifferent attitude is not allowed. In these contexts, this paper explores how Tennessee William's A Streetcar Named Desire involves the audience in the responsibility for what occurs on the stage, in order to urge the audience's ethical judgements and responsible acts. This paper argues that what this play asks of us is not catharsis, the purging of pity and fear, but empathy toward the other's pain, beyond pity and fear, to carry out our responsibility of sharing in and caring for the other's suffering. That is to say that it will be an ethical way to "re-member" Blanche DuBoi-the iconic Williams victim "dis-membered" by traumatic memories and open wounds and is thus unable to complete her grieving and mourning-as one of us, not as the other. It will be the only way to remember right regarding her tragedy.

• 한국정보전자통신기술학회논문지
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• 제15권4호
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• pp.271-282
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• 2022

본 논문에서는 디지털 휴먼 컨텐츠 생성 시스템을 제안한다. 디지털 휴먼 컨텐츠 생성 시스템은 전신 스케닝을 통해 3D AI 모델링 작업을 하고, 3D 모델링 후처리와 텍스쳐링, 리깅 작업으로 제작된다. 이를 가상현실 컨텐츠 정보와 결합함으로써 가상현실 내에서 가상 모델의 자연스러운 동작이 이뤄질 수 있고, 하나의 시스템에서 효율적으로 디지털 휴먼 컨텐츠를 생성할 수 있다. 따라서 자원을 최소화하는 가상현실 기반의 디지털 휴먼 컨텐츠 생성이 가능하도록 하는 효과가 있다. 또한 사람에 의한 3D 모델링 및 텍스쳐링 작업은 전처리 과정을 필요로 하지 않는 자동화된 전처리 공정을 제공하며, 다양한 디지털 휴먼 컨텐츠를 효율적으로 관리하는 기술을 제공고자 한다. 특히 가상 모델을 구성하기 위한 3D 모델링 및 텍스쳐링 등의 전처리 공정은 인공지능에 의해 자동으로 수행되도록 함으로써 신속하고 효율적인 가상 모델 구성이 이뤄질 수 있다는 장점이 있다. 또한 시그니처 모션을 통해 디지털 휴먼 컨텐츠 구성 및 관리가 용이하게 이뤄질 수 있다는 장점이 있다.

• 시큐리티연구
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• 제7호
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• pp.95-124
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• 2004

It can be said that 'the September 11th Terrorist Attacks' in 2001 were not only the indiscriminate attacks on innocent people but also the whole - political, economical and military - attacks on human life. Also, 'the September 11th Terrorist Attacks' can be regarded as the significant events in the history of world, which were on the peak of the super-terrorism or new-terrorism that had emerged from the 1980s. However, if one would have analysed the developments of terrorism from the 1970s, they could have been foreknown without difficulty. The finding from this study can be summarized as the followings, First, in spite that the USA responsive system against terrorism had been assessed as perfect before 'the September 11th Terrorist Attacks', the fragilities were found in the aspects of the response on the new-terrorism or super-terrorism. The previous responsive system before 'the September 11th Terrorist Attacks' had the following defects as the followings: (1) it was impossible to establish the integrated strategy, because the organizations related to the response against terrorism had not integrated; (2) there were some weakness to collect and diffuse the informations related to terrorism; (3) the security system for the domestic airline service in USA and the responsive system of air defense against terrors on aircraft were very fragile. For these reasons, USA government established the 'Department of Homeland Security' of which the President is the head so that the many organizations related to terrorism were integrated into a single management system. And, it legislated a new act to protect security from terrors, which legalized of the wiretapping in spite of the risk of encroachment upon personal rights, increased the jail terms upon terrorists, froze the bank related to terrorist organization, and could censor e-mails. Second, it seem that Korean responsive system against terrors more fragile than that of USA. One of the reasons is that people have some perception that Korea is a safe zone from terrors, because there were little attacks from international terrorists in Korea. This can be found from the fact that the legal arrangement against terrorism is only the President's instruction No. 47. Under this responsive system against terrorism dependent on only the President's instruction, it is expected that there would be a poor response against terrors due to the lack of unified and integrated responsive agency as like the case of USA before 'the September 11th Terrorist Attacks'. And, where there is no legal countermeasure, it is impossible to expect the binding force on the outside of administrative agencies and the performances to prevent and hinder the terrorist actions can not but be limited. That is to say, the current responsive system can not counteract effectively against the new-terrorism and super-terrorism. Third, although there were some changes in Korean government's policies against terrorism. there still are problems. One of the most important problems is that the new responsive system against terrorism in Korea, different from that of USA, is not a permanent agency but a meeting body that is organized by a commission. This commission is controled by the Prime Minister and the substantial tasks are under the National Intelligence Service. Under this configuration, there can be the lack of strong leadership and control. Additionally, because there is no statute to response against terrorism, it is impossible to prevent and counteract effectively against terrorism. The above summarized suggests that, because the contemporary super-terrorism or new-terrorism makes numerous casualties of unspecified persons and enormous nationwide damages, the thorough prevention against terrorism is the most important challenge, and that the full range of legal and institutional arrangements for the ex post counteraction should be established. In order to do so, it is necessary for the government to make legal and institutional arrangements such as the permanent agency for protection from terrorism in which the related departments cooperates with together and the development of efficient anti-terror programs, and to show its willingness and ability that it can counteract upon any type of domestic and foreign terrorism so that obtain the active supports and confidence from citizens.