• Journal of Acupuncture Research
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• 제26권3호
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• pp.133-147
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• 2009

Objectives : To review RCTs on acupuncture treatment for low back pain in order to establish a standard acupuncture treatment model in treating low back pain. Methods : RCT articles on traditional acupuncture treatment for low back pain were searched through online database. Study Quality was assessed using the FEAS. Results : Ten out of the one hundred six articles searched were reviewed. Among the ten articles reviewed, six articles compared acupuncture treatment with no treatment or non-penetrating sham acupuncture. All six articles concluded significantly positive effect of acupuncture compared to the control. Conclusions : The ideal acupuncture treatment model for low back pain was obtained as follows. A sterile disposable stainless steel(0.30mm${\times}$40mm) should be inserted to more than six acupuncture points on the BL, GV and GB meridians such as $BL_23$, $BL_25$, $BL_40$, $BL_60$, $GV_4$ and $GB_30$. Sparrow pecking method to obtain 'de-qi' is recommended and repeated stimulation during the 20 minute retention time is necessary. Ideal treatment frequency would be more than one a week for about 7 weeks.

• Journal of Acupuncture Research
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• 제18권1호
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• pp.40-49
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• 2001

Background and Purpose : There have been many studys about the relationship between the meridians and the acupoints of the twelve meridians, but no study about the extra points. To verify Dong-Shi acupoints, a kind of extra points, we studied the effects on the thermal changes of the ankle region following acupuncture on the Wu-Hu. Object and Methods : This study was researched into clinical statistics for 45 healthy normal students. The object was divided into two groups. One was the control group and the other was the acupuncture group. The acupuncture group was divided into two groups ; ACU-up : The class of ascent thermal change among acupuncture group. ACU-dn : The class of descent thermal change among acupuncture group. First, in the control group, we took a picture at the ankle region(BL60, BL62, GB40, ST41) without any stimulation with the Digital Infrared Thermal Imaging System and did after 10 minutes respectively. Second, in the acupuncture group, we took a picture without any stimulation and then acupuncture on Wu-Hu and took a picture after 10 minutes in the same way respectively. Results : 1. In the control group, average thermal change of BL60, BL62, GB40 and ST41 was decreased(about $0.2^{\circ}C$) after 10 minutes. 2. The skin temperature of all measured parts was significantly lower in the ACU-dn group after 10 minutes. 3. There were no significant differences of thermal change between the control and the acupuncture group, between the control and ACU-up group after 10 minutes. Conclusion : This result indicated that the acupuncture on the Wu-Hu was effective at the ankle region. And so the more study is needed continuously.

• 대한한의학회지
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• 제20권2호
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• pp.128-140
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• 1999

To evaluate the antitumor activity, antimetastatic and immunomodulatory effects of samryongbakchulsankamibang(SBSK) studies were done experimentally, In cytotoxicity against P388, A549. SK-OV-3, B16-F10 and SK-MEL-2. concentration inhibiting cell growth up to below 40% of control was recognized at $10^{-3}g/ml$ of SBSK. In Inhibitory effect on activity of DNA topoisomerase I. the $IC_{50}$ was shown $200-400{\mu}g/ml$ of SBSK. The T/C was 154% in SBSK-treated group in S-180 bearing ICR mice, The concentration inhibiting adhesion of A549 and B16-F10 to complex extracellular matrix up to below 30% of control was recognized at $5{\times}10^{-4}$, $1{\times}10^{-3}\;g/ml$ of SBSK. In pumonary colonization assay with B16-BL/6, a number of colonies in the lungs were decreased significantly in SBSK-treated group as compared with control group, In hematological changes in B16-BL/6 injected C57BL/6, numbers of WBC and platelet were not changed significantly in SBSK-treated groups, In CAM and in vitro neovascularization assay, angiogenesis was inhibited significantly in SBSK-treated group as compared with control group. From above results it was concluded that SBSK could be usefully applied for the prevention and treatment of cancer.

• 동의생리병리학회지
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• 제17권2호
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• pp.525-528
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• 2003

Spatholobus Suberectus dunn. has been applied to blood stasis in oriental medicine. We selected one potent ethyl acetate subfraction-2 from Spatholobus Suberectus Dunn.(SSD) from anti-metastasis screening. It exerted the cytotoxicity against HT1080 and B16BL6 with the IC50 of 60 ug/ml and also significantly inhibited tumor cell induced platelet aggregation (TCIPA). It effectively didn't inhibit cell adhesion of HT1080 to matrigel coated wells, while it inhibited the cell invasion of HT1080 at the doses of 10, 20, 40 μg/ml by Boyden chamber assay. It effectively suppressed lung metastasis by B16BL6 melanoma in C57BL6 mice. These results indicate that the EtOAc subfraction-2 of Spatholobus Suberectus Dunn. can be applied to caner treatment with anti-metastatic activity.

• 한방안이비인후피부과학회지
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• 제12권1호
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• pp.143-153
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• 1999

Background: The vasoreactivity of cerebral artery is currently the subject of increasing interest Transcranial Doppler The purpose of this study was to investigate the analgesic effect of acupuncture in a model of neuropathic pain produced by segmental spinal nerve injury (SSI) in rats. The left L5 and L6 spinal nerves of Sprague-Dawley rats were tightly ligated, and one week later, manual or electro-acupuncture was applied for 30 minutes to the contralateral hindlimb (right side) while the animal was lightly anesthetized with halothane. The mechanical threshold of the paw for ipsilateral (left side) hind limb flinching was determined prior to and 0.5, 1, 2, 4, and 24 hours after termination of acupuncture. The mechanical threshold for flinching was significantly elevated for about 4 hours after manual acupuncture applied to the BL. 60 (Kunlun) point or electro-acupuncture to the BL. 60 and BL. 40 (Weizhong) points. However, manual acupuncture applied to the ST. 36 (Zusanli) point was not effective. Furthermore, systemic naloxone pretreatment had no effect on the acupuncture induced threshold elevation. These data suggests that acupuncture produces a point specific, naloxone independent analgesia in a rat neuropathic pain model. ※ This paper is supported by a grant from the '1996 Jusan Foundation of Wonkwang university.)

• Journal of Acupuncture Research
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• 제17권2호
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• pp.31-39
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• 2000

Object : This study is designed to evaluate the correlation between the data of DITI(Digital Inrared Thermographic Imaging) examination and the changes of clinical symptoms after the therapy of acupuncture in the patients with spondylolisthesis. Contents : The conservative therapy with acupuncture was performed during 3-4weeks. The acupuncture points of BL23, BL24, BL25, BL40, BL57, BL60, BL62, GB30, GB31, ST36, TE3 was used. In the pre- and post therapy, DITI examinations were performed in patients who had spondylolisthes in L-spine X-ray and were treated by acupuncttare simultaneously, and then tried to correlate the results of clinical symptoms with the difference of thermographic findings at pre-and post acupuncture. Setting : The standard routine thermographic exanninations were performed with thermography (DITI) in the 22 patients with spondylolisthesis at pre- and post acupuncture. Patients : Thermographic imaging of 22 cases was analyzed. They had diagnosed spondylolisthes in L-spine X-ray. They were treated by acupuncture and moxibustion therapy in Wonkwang Oriental Hospital from May, 1998 to May, 2000. Results : 1) The causes were congenital (4.5%), overwork (31.85%), trauma (13.65%), degenerative factor(50%) 2) The DITI results showed 45.4% below $0.3^{\circ}C$, 36.4% between 0.3 and $0.5^{\circ}C$, 4.5% between 0.5 and $0.7^{\circ}C$, 9.1% between 0.7 and $0.9^{\circ}C$, and 4.5% over $0.9^{\circ}C$. 3) The results of treatment using pain scale showes that 27.3% of patientsachieved excellent recovery and 54.6% achieved good recovery. After compairing the DITI results before and after treatment, we found 45.4% of patients achieved excellent recovery and 36.4% achieved good recovery. Conclusion : Acupuncture showed good results over 81.9% in clinical evaluation and 81.8% in DITI. Thermographic examination was valuable in the evaluation of therapeutic effect of acupuncture treatment.

• Journal of the Korean Wood Science and Technology
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• 제25권2호
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• pp.52-60
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• 1997

Hornbeam trees(Carpinus laxiflora BL.) are growing in Korea and have good characteristics such as relatively high density, fine texture, split- resistance, and white colour. However, they have seldom been used as manufacturing materials This study was carried out to evaluate the possibility of using hornbeam wood as bent, wood furniture materials. Softening methods were steaming and micro-wave heating. The specimens of $15{\times}15{\times}350mm$ were used green or air-dried, and were steamed at $100^{\circ}C$ for 20min, or microwave heat ed f or 60 seconds. The bending processing conditions are showed in Table 3. The minimum solid-bending radii of air-dried wood were 40mm for steaming and 200mm for micro-wave heating, respectively. And that of green wood were 40mm for micro-wave heating. In conclusion, both of the steamed wood and micro-wave heated green wood showed very good solid bending processing properties, but micro-wave heated air-dried wood were not sufficient for bent-wood furniture.

• Journal of the Korean Wood Science and Technology
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• 제11권2호
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• pp.52-60
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• 1983

Hornbeam trees(Carpinus laxiflora BL.) are growing in Korea and have good characteristics such as relatively high density, fine texture, split-resistance, and white colour. However, they have seldom been used as manufacturing materials This study was carried out to evaluate the possibility of using hornbeam wood as bent-wood furniture materials. Softening methods were steaming and micro-wave heating. The specimens of $15{\times}15{\times}350mm$ were used green or air-dried, and were steamed at $100^{\circ}C$ for 20min, or microwave heated for 60 seconds. The bending processing conditions are showed in Table 3. The minimum solid-bending radii of air-dried wood were 40mm for steaming and 200mm for micro-wave heating, respectively. And that of green wood were 40mm for micro-wave heating. In conclusion, both of the steamed wood and micro-wave heated green wood showed very good solid bending processing properties, but micro-wave heated air-dried wood were not sufficient for bent-wood furniture.

• 대한한의학회지
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• 제31권3호
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• pp.66-78
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• 2010

Background: Peripheral nerve injuries are a commonly-encountered clinical problem and often result in a chronic pain and severe functional deficits. Objectives: The aim of this study was to evaluate the effects of acupuncture on the descending pain and the recovery of the locomotor function that follows sciatic crushed nerve injury in rats. Method: In order to assess the effects of acupuncture on the descending pain and functional recovery, we investigated the walking track analysis, brain-derived neurotrophic factor (BDNF) and its receptor tyrosine receptor kinase B (TrkB) expression in the sciatic nerve, and on the expressions of c-Fos and nitric oxide synthase in the paraventricular nucleus (PVN) of the hypothalamus and in the ventrolateral periaqueductal gray (vlPAG) region resulting from sciatic crushed nerve injury in rats. Results: Acupuncture treatment at Huantiao (GB30), Yanglingquan (GB34), and Weizhong (BL40) facilitated functional recovery. C-Fos and nitric oxide synthase expressions in the brain and BDNF and TrkB expressions in the sciatic nerve were decreased by acupuncture treatment. The most potent effects of acupuncture were observed at the GB30 acupoint. Conclusion: It is possible that acupuncture can be used for pain control and functional recovery from sciatic nerve injury.

• International Journal of Industrial Entomology and Biomaterials
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• 제13권1호
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• pp.7-14
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• 2006

A breeding programme was initiated during 2001 to introduce sex-limited larval markings to a productive multivoltine breed - BL67 from an inbred sex-limited line, MY1 (SL) maintained at Central Sericultural Research and Training Institute, Mysore. Introgressive hybridization, recurrent backcrossing for six generations followed by sib-mating resulted in synthesis of a new multivoltine silkworm breed BL67 (SL) with sex-limited larval markings. The new breed was studied for combining ability by crossing with eight bivoltine breeds viz., $NB_4D_2,\;CSR_2,\;CSR_2 (SL),\;CSR_2,\;CSR_4,\;CSR_8,\;CSR_{18}\;and\;CSR_{19}$. General combining ability effects of the new breed showed its superiority over the popular Pure Mysore by expressing significant GCA effects for six out of twelve characters whereas the results are on par with the original multivoltine breed. The hybrid $BL67(SL){\times}CSR2(SL)$ excelled in several quantitative characters such as pupation rate (90.2%), cocoon weight (1.97 g), cocoon shell weight (40 cg), cocoon shell ratio (20.3%), filament length (918 m), denier (2.96), raw silk percentage (14.96%) and neatness (90 p). Studies on cocoon size variability revealed that the cocoons of $BL67(SL){\times}CSR2(SL)$ were found comparatively uniform showing less standard deviation of 6.55 and co-efficient of variation of 3.91 %. The suitability of newly developed breed for easy grain age operation and commercial exploitation with promising hybrid have been discussed.