• Title/Summary/Keyword: BIC%

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THE INFLUENCE OF THE INITIAL STABILITY AFTER DENTAL IMPLANT INSTALLATION ON THE OSSEOINTEGRATION (임프란트 식립시 초기 안정성이 골유착에 미치는 영향)

  • Lee, Young-Hoon;Kim, Yeo-Gab;Choi, Byung-Jun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.30 no.6
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    • pp.518-528
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    • 2008
  • Purpose: The long-term experience of using osseointegrated implants for prosthetic rehabilitation of the edentulous patients shows that high success rates can be predictably achieved. Primary implant stability has been identified to be a prerequisite to achieve osseointegration. In this study, we set up the amount of removed bone so that it differed on implant installation site for each group. The influence of each initial stability on secondary stability and osseointegration was compared with time lapse using resonance frequency analysis and histomorphometric analysis. Materials and methods: A total 27 US $II^{(R)}$ (Osstem, Korea) implants were placed in the mandibular edentulous area of 3 beagle dogs. The implant site was prepared by the conventional technique with drills, and three experimental groups were divided into under-drilling group, normal-drilling group and over-drilling group. The Implant Stability Quotient (ISQ) was measured at intervals of immediately, 4, 8, 12 weeks after placement using $Osstell^{(R)}$ mentor RFA. After the animals were sacrificed, histomorphometric evaluation was executed for measuring BIC and BD. Results: 1) The under-drilled group showed most high ISQ value for whole experiment period. 2) Bone-to-implant-contact(BIC) showed the tendency to be increased gradually as the experiment period passed except the 8 weeks of the normal group. 3) The under-drilled group showed most high bone density(BD) level for whole experiment period, and it was expressed the aspect to be increased gradually according to an experiment period passage in the average of all group. 4) Resonance frequency analysis and histomorphometric analysis are presumed by generally proportional. Conclusions: As this research result, it seems that there are some correlation between resonance frequency analysis and histomorphometric analysis. As are accomplished osseointegration stably so that more superior at the region which the overpressure comes to add, it will be applicable method in clinical field.

Marginal bony changes in relation to different vertical positions of dental implants

  • Yi, Jung-Myung;Lee, Jae-Kwan;Um, Heung-Sik;Chang, Beom-Seok;Lee, Min-Ku
    • Journal of Periodontal and Implant Science
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    • v.40 no.5
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    • pp.244-248
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    • 2010
  • Purpose: The purpose of this study was to radiographically evaluate marginal bony changes in relation to different vertical positions of dental implants. Methods: Two hundred implants placed in 107 patients were examined. The implants were classified by the vertical positions of the fixture-abutment connection (microgap): 'bone level,' 'above bone level,' or 'below bone level.' Marginal bone levels were examined in the radiographs taken immediately after fixture insertion, immediately after second-stage surgery, 6 months after prosthesis insertion, and 1 year after prosthesis insertion. Radiographic evaluation was carried out by measuring the distance between the microgap and the most coronal bone-to-implant contact (BIC). Results: Immediately after fixture insertion, the distance between the microgap and most coronal BIC was $0.06{\pm}0.68\;mm$; at second surgery, $0.43{\pm}0.83\;mm$; 6 months after loading, $1.36{\pm}0.56\;mm$; and 1 year after loading, $1.53{\pm}0.51\;mm$ ($mean{\pm}SD$). All bony changes were statistically significant but the difference between the second surgery and the 6-month loading was greater than between other periods. In the 'below bone level' group, the marginal bony change between fixture insertion and 1 year after loading was about 2.25 mm, and in the 'bone level' group, 1.47 mm, and in 'above bone level' group, 0.89 mm. Therefore, the marginal bony change was smaller than other groups in the 'above bone level' group and larger than other groups in the 'below bone level' group. Conclusions: Our results demonstrated that marginal bony changes occur during the early phase of healing after implant placement. These changes are dependent on the vertical positions of implants.

A Study on Determining the Prediction Models for Predicting Stock Price Movement (주가 운동양태 예측을 위한 예측 모델결정에 관한 연구)

  • Jeon Jin-Ho;Cho Young-Hee;Lee Gye-Sung
    • The Journal of the Korea Contents Association
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    • v.6 no.6
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    • pp.26-32
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    • 2006
  • Predictions on stock prices have been a hot issue in stock market as people get more interested in stock investments. Assuming that the stock price is moving by a trend in a specific pattern, we believe that a model can be derived from past data to describe the change of the price. The best model can help predict the future stock price. In this paper, our model derivation is based on automata over temporal data to which the model is explicable. We use Bayesian Information Criterion(BIC) to determine the best number of states of the model. We confirm the validity of Bayesian Information Criterion and apply it to building models over stock price indices. The model derived for predicting daily stock price are compared with real price. The comparisons show the predictions have been found to be successful over the data sets we chose.

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A Non-stationary frequency analysis for annual daily maximum rainfalls(ADMRs) using mixed Gumbel distribution of bayesian approach (Bayesian 기법의 혼합 Gumbel 분포를 활용한 연최대일강우량에 대한 비정상성 빈도해석)

  • Choi, Hong-Geun;Yoo, Min-Seok;Han, Young-Cheon;Kwon, Hyun-Han
    • Proceedings of the Korea Water Resources Association Conference
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    • 2018.05a
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    • pp.312-312
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    • 2018
  • 우리나라의 기후 지형적 특성에 따라 연강수량의 50% 이상이 여름철에 내리며 이러한 짧은 기간에 집중적으로 내리는 강수패턴 조건하에서 수공구조물 설계시 대부분 극치빈도분석을 활용한다. 우리나라의 경우 단일 Gumbel 분포를 활용한 극치빈도분석을 많이 이용한다. 하지만, 최근 이상기후로 인하여 전세계적으로 강수패턴의 특징이 급격히 변하고 있으며, 우리나라의 강수패턴 또한 바뀌어가고 있다. 연강수량의 대부분은 태풍과 장마로 인한 강수량으로 이루어져 있고, 일반적으로 두 개의 모집단으로 이루어진 형태를 보인다. 앞선 연구에서 두 개 이상의 첨두를 가지는 형태의 연최대강수량 자료에 대해 8개의 지속시간별(1, 2, 3, 6, 9, 12, 18, 24hr)로 Bayesian 기법의 단일 Gumbel 분포형과 혼합 Gumbel분포형 기반의 극치빈도분석 결과를 비교하였고, 혼합 Gumbel 분포형이 이중첨두 부분의 거동을 효과적으로 모의하는 것을 확인하였다. 본 연구에서는 이상기후로 인한 강수량의 특징의 급격한 변화에 일정한 패턴이 있음을 가정하고 이중첨두의 연 최대일강수량 자료에 대해 혼합 Gumbel 분포형 기반 비정상성 빈도분석을 실시하였다. 정상성 빈도분석과의 비교를 위해 확률분포의 매개변수 산정시 우도함수를 Bayesian 기법을 통해 산정하여 각 분포형의 Bayesian information criterion(BIC) 값을 비교하였다. 비정상성일 경우의 BIC 값이 정상성일 경우 보다 작게 산정되었고, 강수패턴이 경향성을 가지는 것으로 판단할 수 있었다. 비정상성 혼합 Gumbel 분포형 모델은 최근 급격한 강수패턴의 변화에 대한 대응책으로서 활용성이 높을 것으로 기대된다.

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Design of Reconfigurable Dual Polarization Patch Array Antenna (재구성 이중편파 패치 배열 안테나 설계)

  • Won Jun Lee;Young Jik Cha
    • Journal of Advanced Navigation Technology
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    • v.27 no.4
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    • pp.463-468
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    • 2023
  • In this paper, we proposed reconfigurable dual polarization patch array antenna that can select two polarizations(Vertical, RHCP) using defected ground structure and Pin diode. The proposed antenna was designed arranging a circular polarization patch antenna implemented with a square microstrip patch and two slots 3x3 at 25.8mm placed, a half-wavelength of 5.8 GHz. Conect the pin diode and the capacitor to the slot diagonally placed on the ground of each antennas, and select polarization using the open/short operating according to the application of DC voltage to the pin diode. As a result of the design, the gain of the antenna is 11.7 dBi at vertical polarization and 11.6 dBic at RHCP. The axial ratio is 20.3 dB at 1.8 dB vertical polarization at RHCP. Mutual Coupling is Maximum to -20.8 dB for vertical polarization and Maximum to -30.1 dB for RHCP.

Assessing reproductive performance and predictive models for litter size in Landrace sows under tropical conditions

  • Praew Thiengpimol;Skorn Koonawootrittriron;Thanathip Suwanasopee
    • Animal Bioscience
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    • v.37 no.8
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    • pp.1333-1344
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    • 2024
  • Objective: Litter size and piglet loss at birth significantly impact piglet production and are closely associated with sow parity. Understanding how these traits vary across different parities is crucial for effective herd management. This study investigates the patterns of the number of born alive piglets (NBA), number of piglet losses (NPL), and the proportion of piglet losses (PPL) at birth in Landrace sows under tropical conditions. Additionally, it aims to identify the most suitable model for describing these patterns. Methods: A dataset comprising 2,322 consecutive reproductive records from 258 Landrace sows, spanning parities from 1 to 9, was analyzed. Modeling approaches including 2nd and 3rd degree polynomial models, the Wood gamma function, and a longitudinal model were applied at the individual level to predict NBA, NPL, and PPL. The choice of the best-fitting model was determined based on the lowest mean and standard deviation of the difference between predicted and actual values, Akaike information criterion (AIC), and Bayesian information criterion (BIC). Results: Sow parity significantly influenced NBA, NPL, and PPL (p<0.0001). NBA increased until the 4th parity and then declined. In contrast, NPL and PPL decreased until the 2nd parity and then steadily increased until the 8th parity. The 2nd and 3rd degree polynomials, and longitudinal models showed no significant differences in predicting NBA, NPL, and PPL (p>0.05). The 3rd degree polynomial model had the lowest prediction standard deviation and yielded the smallest AIC and BIC. Conclusion: The 3rd degree polynomial model offers the most suitable description of NBA, NPL, and PPL patterns. It holds promise for applications in genetic evaluations to enhance litter size and reduce piglet loss at birth in sows. These findings highlight the importance of accounting for sow parity effects in swine breeding programs, particularly in tropical conditions, to optimize piglet production and sow performance.

Effects of adjacent periodontitis on osseointegrated dental implants

  • Keun-Soo Ryoo;Kyoung-Hwa Kim;Young-Dan Cho;Yang-Jo Seol ;Young Ku
    • Journal of Periodontal and Implant Science
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    • v.54 no.4
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    • pp.280-291
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    • 2024
  • Purpose: This study aimed to investigate whether new-onset periodontitis or apical periodontitis in the adjacent teeth affects osseointegrated dental implants in a beagle dog model. Methods: One control group and 2 experimental groups (periodontitis and apical periodontitis groups) were defined based on the presence of experimental periodontitis or apical periodontitis, with 1 beagle dog randomly assigned to each group. The mandibular second and fourth premolars on both sides of the 3 beagles were extracted. Eight weeks after extraction, 4 bone-level implant fixtures, 2 on both sides of each mandible, were placed in each beagle. Six weeks after implant surgery, healing abutments were connected. After sufficient osseointegration, plaque control was performed in the control group, while periodontitis and apical periodontitis were induced in the experimental groups. The beagles were euthanized for histological analyses 20 weeks after induction of experimental periodontitis. Statistical analyses were performed using the Kruskal-Wallis test with the Bonferroni correction to compare the 3 groups. Results: The implants in the control and apical periodontitis groups were well-maintained, while those in the periodontitis group showed clinical signs of inflammation with bone resorption. The bone-to-implant contact (BIC) and bone area values in the periodontitis group were lower than those in the other groups. The distance between the implant shoulder and the first BIC was significantly greater in the periodontitis group than in the control group (P<0.05). Conclusions: The presence of periodontitis in adjacent teeth can pose a risk to dental implants, potentially resulting in peri-implantitis. However, this was not observed for apical periodontitis. Within the limitations of this study, periodontal care is necessary to reduce the impact of periodontitis in adjacent teeth on osseointegrated implants.

Bone-implant contact and mobility of surface-fronted orthodontic micro-implants in dogs (성견에서 표면처리된 교정용 마미크로 임플랜트의 골 접촉률 및 동요도)

  • Park, Seung-Hyun;Kim, Seong-Hun;Ryu, Jun-Ha;Kang, Yoon-Goo;Chung, Kyu-Rhim;Kook, Yoon-Ah
    • The korean journal of orthodontics
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    • v.38 no.6
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    • pp.416-426
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    • 2008
  • The purpose of this study was to evaluate the mobility and ratio of the bone-implant contact (BIC) of a sandblasted, large grit and acid-etched (SLA) orthodontic micro-implant. Methods: Ninety-six micro-implants (48 SLA and 48 machined) were implanted in the upper and lower buccal alveolar bone, and palatal bone of four beagle dogs. Two weeks after surgery, orthodontic force (150-200 g) was applied. Two beagles were sacrificed at 4-weeks and the other two at 12-weeks. Histomorphometric comparisons were made between the SLA experimental group and the machined micro-implant as a control group to determine the ratio of contact between the bone and implant. Micro-implant mobility was also evaluated using $Periotest^{(R)}$. Results: Periotest values showed no statistically significant difference in the upper alveolar and palatal bone between groups except for the lower buccal area. BIC in the upper buccal area showed no significant difference between groups both at 4-weeks and 12-weeks. However, both the groups showed a significant difference in BIC ratio in the rest of the experimental areas between 4 weeks and 12 weeks. The experimental group showed active bone remodeling around the bone-implant interface compared to the control group. Conclusions: There were significant differences in the BIC and the Periotest values between the surface-treated and machined micro-implants according to bone quality in the early stage.

Osseointegration of zirconia implant in the tibia of pigs (돼지의 경골에 식립된 지르코니아 임플란트의 골유착에 관한 연구)

  • Kim, Lee-Kyoung;Cho, In-Ho
    • The Journal of Korean Academy of Prosthodontics
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    • v.51 no.3
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    • pp.190-198
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    • 2013
  • Purpose: The purposes of this study were to investigate osseointegration around zirconia implants which had machined or alumina sandblasted surface, and to compare the results with titanium implants. Materials and methods: The study was performed on the tibia of 6 pigs. Three types of implants were investigated: group T-titanium implant, group Z-machined zirconia implant, group ZS-alumina sandblasting treated zirconia implant. Zirconia implants were manufactured from yttria-stabilized tetragonal zirconia polycrystalline (Acucera Inc., Pocheon, Korea). A total of 36 implants were installed in pigs' tibias. After 1, 4 and 12 weeks of healing period, the periotest and the histomorphometric analysis were performed. The data were analyzed using one-way ANOVA and significance was assessed by the Scheffe test (${\alpha}=.05$). Results: In the measurement of surface roughness, highest Ra value was measured in group T with significant difference. No significant differences were found among groups regarding Periotest values. After 1 week, in comparison of bone to implant contact (BIC), group Z showed higher value with significant difference. In comparison of bone area (BA), group T and group Z showed higher value with significant difference than group ZS. After 4 weeks, in comparison of BIC, group T showed higher value with significant difference. Comparison of BA showed no significant difference among each implant. After 12 weeks, the highest mean BIC values were found in group T with significant difference. Group ZS showed higher BIC value with significant difference than group Z. In comparison of BA, group T and group ZS showed higher value with significant difference than group Z. Conclusion: Zirconia implant showed low levels of osseointegration in this experiment. Modification of surface structure should be taken into consideration in designing zirconia implants to improve the success rate.

The Study of Spontaneous Developmental Abnormalities and Toxicology of Benomyl and Its Metabolite on Salamander, Hynobius leechii.

  • Park, Yong-Uk
    • Proceedings of the Korea Society of Environmental Biology Conference
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    • 2005.12a
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    • pp.38-45
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    • 2005
  • The egg bags of Korean salamander(Hynobius leechii) were collected from farmlands in Gyeongsangnam-do area. The assumed breeding time, numerical variation of embryos in each egg bag, mortality and the rates of abnormalities were investigated. The toxicity of benomyl, the metabolite carbendazim and BIC which were frequently spread in agricultural area and caused spontaneous embryonic malformation was investigated. The assumed breeding time between the end of February and the end of March has the difference about a month because of a habitat and it takes about 2 or 3 weeks from laying eggs to hatching. The length of each egg bag and the number of embryos were very varied in each area. It is due to geographical variation. Among egg bags in total study area, only 406 of egg bags(17.70% of total egg bags) developed all of embryos to normal larvae, and 78.49% of total embryos were normally developed. The patterns of spontaneous embryonic malformation were 26 species from A to Z and the abnormal patterns in individual were 8 species and above. the geographical differences about the abnormal pattern were identified and 11 habitats categorized 4 groups. The most frequent abnormality in Gyeongsangnam-do area is the dysplasia of external gill. The caudal dysplasia, abdominal blister and dysplasia of fin were also frequently observed. Individuals showing severe external defect were histologically studied and they showed retinal hypo-pigmentation, thyroid carcinoma, somatic muscular dysplasia, degeneration of cephalic neuron and various organ dysplasia. Benomyl and carbendazim were treated by 10pM$^{\sim}$10uM and BIC was treated by 1$^{\sim}$40ppm to know the effect of toxicity about toxic substance of salamander. After benomyl was treated, a survival rate was sharply dropped from 2 to 8 days. $LC_{100}$ identified in $1{\mu}M$, $LC_{50}$ identified between 100nM and $1{\mu}M$. $EC_{50}$ was assumed between 10nM and 100nM. The prevalent external malformation was abdomen swelled abnormally and histo-pathological effects were abdomen, neural tube and lens hernia. This suggests that benomyl is the toxicitic substance which inhibits the development of digestive system and nervous system. The result of treated carbendazim was similar to that of the treated benomyl. The survival rate is sharply dropped between 2 and 6 days. $LC_{100}$ was identified $1{\mu}M$ and $LC_{50}$ was identified between 10nM and 100nM. This shows that cabendazim has stronger lethal toxicity than benomyl. Ventral blister, eye dysplasia and cephalic dysplasia in the individual of external malformation mean that cabendazim affected nervous system much more than benomyl. Because the toxicity of BIC affected less in the beginning but affected more in the near hatching period, the period causing toxicity is somewhat different. $LC_{100}$ identified near 40ppm and $LC_{50}$ identified near 25ppm. The external defect shows mainly ventral blister and histo-pathological results show intestinal deformities. This result suggests the BIC inhibited strongly the development of digestive system. These abnormal developments may be caused by antimitotic action, inhibition of tubulin complex, destruction of microtubule, inhibitions of neurulation and closing of neural fold, and by the inhibition of movement of neural crest cells of benomyl. These abnormal developments may be caused by the rupture of epithelium, the loss of microtubule, the reduction of spindle size, the inhibition of spindle assembly formation, the destruction of spindle poles of carbendazim. These abnormal developments may be caused cytotoxicity by inhibition of the synthesis of a number of macromolecules and similar reaction the inhibition of benomyl.

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