• 한국원자력학회:학술대회논문집
• /
• 한국원자력학회 1995년도 추계학술발표회논문집(1)
• /
• pp.67-72
• /
• 1995

최근 선진 원자력 개발국들이 새로운 평가 핵자료집들을 계속하여 공개하고 있다. 이 핵자료들을 노심 채석에 적용하기 위한 연구의 일환으로 최근에 발표된 ENDF/B-V1.2 평가 핵자료집을 이용하여 CASMO-3의 단면적 Data Library를 만들어 검증해 보았다. 평가 핵자료집의 개선 정도와 계산상으로 만들어진 Library와 실제 사용되는 Library의 차이를 알아보기 위하여 BNDF/B-IV도 같이 처리하여 검증하였다. 유효증배계수와 integral parameter들을 비교한 결과 ENDF/B-VI의 유용성과 일관성이 입증되었고, 단면적 Library의 수정 작업에 관한 연구의 필요성도 제기되었다.

• Applied Biological Chemistry
• /
• 제35권4호
• /
• pp.242-247
• /
• 1992

서울시 중량천 하수처리장의 활성오니로부터 총 20주의 pentachlorophenol(PCP) 내성균주들을 분리하여 B. sphaericus B-2와 B. schlegelii B-13를 포함한 Bacillus spp. 9주, Corynebacterium spp. 4주, Staphylococcus aureus S-1 1주, Aeromonas spp. A-19 1주, Arthrobacter LN-3 1주로 동정하였다. 이 균주들은 $200{\sim}300\;ppm$ PCP와 0.1% glucose가 포함된 mineral salt 배지에서 생육하였으며 PCP를 분해하는 종류 13주와 분해하지 못하고 흡착 혹은 흡수하는 종류 7주로 구분되었다. PCP 분해균주들은 대부분 배양 24시간후 생육이 최고에 도달하여 PCP를 약 $75{\sim}90%$ 분해하였으며 PCP 흡착 혹은 흡수하는 균주들은 흡착한 PCP를 배양 24시간 이후 또는 72시간 이후에 방출하였다. PCP 분해균주 B. sphaericus B-2, B. schlegelii B-13의 분해 산물을 TLC를 이용하여 검출한 결과 B. sphaericus B-2의 배양액에서 2-chlorophenol, B. schlegelii B-13에서는 2,4-dichlorophenol로 추정되는 물질과 4종의 분해산물로 보이는 물질들을 검출하였다.

• KSBB Journal
• /
• 제28권2호
• /
• pp.131-136
• /
• 2013

The hydrolysates prepared with various enzyme digestion of Capsosiphon fulvescens were used to measure the inhibitory effects against angiotensin I converting enzyme (ACE). The commercially available enzymes such as Celluclast, Viscozyme, Lysing enzyme, Flavourzyme, Alcalase and Pectinex were used to digest C. fulvescens and produce hydrolysates. The maximum ACE inhibitory activity was observed using Alcalase hydrolysis (72.9%). The optimal conditions of Alcalase extraction were pH 8.0 and extraction time for 12 hr. The hydrolysates were fractionated using preparative-LC and anion-exchange chromatography on DEAE-cellulose and the fraction B and B-2 were isolated. The ACE inhibitory activity of fraction B-2 by anion-exchange chromatography was 82.6%. The molecular weight of fraction B-2 estimated using size exclusion chromatography was about 1 kDa. The monosaccharide composition of the fraction B-2 was determined to be mannose (1.1%), glucuronic acid (1.3%), galactose (1.3%) and glucose (96.3%).

• 한국전자파학회:학술대회논문집
• /
• 한국전자파학회 2001년도 종합학술발표회 논문집 Vol.11 No.1
• /
• pp.279-282
• /
• 2001

Ka-Band MMIC Mixer 칩 을 InGaAs/GaAs p-HEMT 공정의 Schottky Diode을 이용하여 개발하였다 설계된 칩은 상/하향 주파수 변환기로 사용할 수 있으며 Double Balance 구조로 되어있다. 크기 3.0$\times$2.4 $\textrm{mm}^2$ 칩의 On-wafer측정 결과, RF주파수 24～27 GHz와 LO주파수 16.28 GHz, IF 주파수 7.72～10.72GHz 상/하향에 대해서, 변환손실 <7dB와 Port별 격리도 >20dBc의 특성을 얻었다.

• 한국전자거래학회:학술대회논문집
• /
• 한국전자거래학회 2003년도 종합학술대회 논문집
• /
• pp.28-32
• /
• 2003

ㆍ사업목표 -50인 미만의 중소업체가 전체 생산의 72％를 차지하는 금형산업의 경쟁력 강화와 전자상거래를 통한 가치사슬의 개선 ㆍ사업규모 -사업기간 ： 2001.7.1∼2004.6.30 -사업비용 ： 총 29.4억원(정부 20.3억/민간 9.1억) ㆍ추진주체 ： 금형조합 컨소시엄 -주관기업(기관) ： (주)허브닷컴 -참여기업(기관)：한국금형공업협동조합 및 재영솔루텍(주), 기신정기(주)외 오프라인 금형 및 금형부품기업 5개사, (주)일렉트로피아 외 IT기업 3개사(중략)

• 한국전기전자재료학회:학술대회논문집
• /
• 한국전기전자재료학회 1997년도 추계학술대회 논문집
• /
• pp.68-72
• /
• 1997

In this paper, to obtain the YbB $a_2$C $u_3$ $O_{x}$ superconductor, the mixed Powders of Y $b_2$ $O_3$, BaC $O_3$, CuO and Y $b_2$BaCu $O_{5}$, BaCu $O_2$ were used and the various calcining conditions were applied for the 123 phase of YbB $a_2$C $u_3$ $O_{x}$. Samples were prepared by the mixed oxide method and calcined with various temperatures of 88$0^{\circ}C$ ~91$0^{\circ}C$ . It was observed that the distribution of YbB $a_2$C $u_3$ $O_{x}$ phase which was calcined at 90$0^{\circ}C$ for 12 hours and 99 hours. But the result of long time calcination(99 hrs), the 123 phase of YbB $a_2$C $u_3$ $O_{x}$ was existed between 89$0^{\circ}C$ and 91$0^{\circ}C$ . And the best case could be obtained at the calcination temp. of 90$0^{\circ}C$ from the mixed Powder of YbB $a_2$C $u_3$ $O_{5}$ and Bacu $O_2$ which were prepared individually.idually.

• 한국식품위생안전성학회지
• /
• 제21권2호
• /
• pp.76-81
• /
• 2006

총 아플라톡신 분석을 위한 최적의 추출 및 용출조건을 확립하여 최적의 전처리 조건을 확립하였다. 추출용매는 70% methanol 용액에 NaCl을 각각 1% 첨가한 용액을 사용하였고, 정제용 컬럼인 immunoaffinity column을 이용하여 acetonitrile 3 mL를 용출용매로 사용하여 아플라톡신 혼합용액의 분리능을 좋게 하였다. 검출한계는 0.05 ng/g 수준이였고, 식품의 유형별 총 아플라톡신($B_1,\;B_2,\;G_1,\;G_2$)의 회수율은 곡류 $74.1{\sim}95.5%,\;83.7{\sim}98.8%,\;80.4{\sim}102.4%$ 및 $72.8{\sim}76.5%$, 두류 $85.8~87.5%,\;83.8{\sim}90.7%,\;92.0{\sim}94.5%$ 및 $60.6{\sim}65.6%$, 견과류 $84.6{\sim}97.1%,\;86.0{\sim}94.1%,\;95.5{\sim}111.5%$ 및 $71.0{\sim}89.9%$, 가공식품 $81.5{\sim}87.1%,\;82.8{\sim}85.8%,\;85.4{\sim}92.7%$ 및 $68.9{\sim}76.4%$, 건조과실류 $83.6{\sim}93.5%,\;78.1{\sim}90.4%,\;93.0{\sim}108.5%$ 및 $64.9{\sim}78.5%$, 기타식품 $72.5{\sim}98.3%,\;73.1{\sim}96.4%,\;83.5{\sim}107.2%$ 및 $64.2{\sim}75.8%$를 보여주었다.

• Bulletin of the Korean Chemical Society
• /
• 제33권5호
• /
• pp.1505-1508
• /
• 2012

Protein tyrosine phosphatase 1B (PTP1B) is a key factor in negative regulation of the insulin pathway, and is a promising target for the treatment of type-II diabetes, obesity and cancer. Herein, compound ($\mathbf{4}$) was first observed to have moderate inhibitory activity against PTP1B with an $IC_{50}$ value of $13.72{\pm}1.53{\mu}M$. To obtain more potent PTP1B inhibitors, we synthesized a series of chalcone derivatives using compound ($\mathbf{4}$) as the lead compound. Compound $\mathbf{4l}$ ($IC_{50}=3.12{\pm}0.18{\mu}M$) was 4.4-fold more potent than the lead compound $\mathbf{4}$ ($IC_{50}=13.72{\pm}1.53{\mu}M$), and more potent than the positive control, ursolic acid ($IC_{50}=3.40{\pm}0.21{\mu}M$). These results may help to provide suitable drug-like lead compounds for the design of inhibitors of PTP1B as well as other PTPs.

• 통합자연과학논문집
• /
• 제9권1호
• /
• pp.72-79
• /
• 2016

Hexane, ethyl acetate and methanol extracts of whole plant of Boerhavia diffusa were screened for phytochemical and biological activities. Qualitative phytochemical screening via colorimetric method and the quantitative estimation of phenolic and flavonoid content were performed. Antioxidant assay using DPPH scavenging method was studied. Antimicrobial screening of plant extracts was done by cup diffusion technique. Cytotoxic activity of B. diffusa was studied by brine shrimp bioassay and anthelminthic activity was evaluated in vitro in Pheretima posthuma. This study revealed B. diffusa as a source of various phyto-constituents such as alkaloids, glycosides, saponins, tannins, carbohydrates, cardiac glycosides, flavonoids and terpenoids. Quantitative estimation of total phenol was found to be maximum in BEE i.e. $29.73{\pm}0.88$, BME $19.8{\pm}2.02$ and in BHE $9.15{\pm}0.304mgGAE/g$. Similarly, the total flavonoid content was found to be $17.44{\pm}0.75$ in BEE, $14.43{\pm}0.23$ in BHE and 3.678 mg QE/g in BME. Ethyl acetate extract showed its antibacterial activity against all tested pathogens except Escherichia coli whereas Staphylococcus aureus and Salmonella Typhi were resistant to methanol and hexane extract. The zone of inhibition (ZOI) of ethyl acetate extract against S. Typhi and B. cereus was found to be 18 mm and 14 mm respectively. The MIC value of BEE in S. Typhi was $3.125{\mu}g/ml$ and in B. cereus was $12.5{\mu}g/ml$. The preliminary screening of anticancer property of B. diffusa i.e. BSLT in methanol was found to be $165.19{\mu}g/ml$. B. diffusa was also found to contain anthelmintic property. The study helped in further exploration of medicinal properties of B. diffusa by phytochemical screening and biological activities paving the path for study and investigation in this plant.

• 한국결정학회지
• /
• 제8권2호
• /
• pp.138-143
• /
• 1997

Isoimperatorin, 4-[3-methyl-2-butenly)oxy]=7H-furo[3,2-g][1] benzopyran-7-one의 분자 및 결정구조를 X-선 회절법으로 연구하였다. 이 결정의 분자식은 C16H14O4, 결정계는 단사정계이고 공간군은 P21/c이다. 단위세포상수는 a=8.865(1) Å, b=9.331(1) Å, c=16.156(1) Å이며 β=98.12(1)', V=1322.9(2) Å3, T=293(2)K, z=4이다. 구조해석에 사용한 X-선은 Cu Kα선(λ=1.5418 Å)이다. 구조는 직접법으로 풀었으며, 최소자승법으로 정밀화하였다. 최종 신뢰도 R값은 Fo>4o(F0)인 1922개의 독립회절데이타에 대해 5.72% 이다.