• 제목/요약/키워드: B13

Search Result 7,821, Processing Time 0.034 seconds

Efficacy of rifampin and streptomycin in Sprague-Dawley ratsinfected with Brucella abortus (Brucella abortus 감염 흰쥐에서의 rifaampin과 streptomycin의 치료효과)

  • Baek, Byeong-Kirl;Choi, Chun-ki;Lim, Chae-woong;Lee, John-hwa;Kim, Byeong-Soo;Lee, Sung-il;Hur, Jin;Ibulaimu, Kakoma
    • Korean Journal of Veterinary Research
    • /
    • v.44 no.3
    • /
    • pp.433-439
    • /
    • 2004
  • This study was carried out to investigate the efficacy of rifampin with or without streptomycin in male Sprague-Dawley (SD) rats experimentally inoculated with Brucella abortus. Thirty rats were intraperitoneally inoculated with $1.0{\times}10^9$colony-forming units of B. abortus. They were divided into 3 groups by treatment with antibiotic. 10 rats in Group A were orally administrated with rifampin, 10 rats in Group B with rifampin orally and with streptomycin intramuscularly over 12 weeks starting at 1 week post infection (PI). A placebo recipient in Group C was inoculated with sterile saline without antibiotics. All animals were monitored by tube agglutination test (TAT) and AMOS-PCR to evaluate the efficiency of the antibiotics to B. abortus infection. The antibody titers in Groups A, B and C were 1:400, 1:400 and 1:800 as measured by TAT at the first week PI, respectively. The antibody titer in Group A decreased to 1:100 by the 13th week PI. That in the control group was observed as high antibody titer until 13th weeks PI, but the antibody response in Group B was low(1:50) from the 5th week to the 13th week PI. AMOS-PCR there was evidence of relapse of B. abortus in group A in liver and spleen specimens at the 13th week PI. B. abortus DNA was detected in Group C in liver and spleen specimens from the 1st week to 13th week PI by AMOS-PCR. However AMOS-PCR could not detect any organism in Group B from the 3rd week PI until the end of the study. This study demonstrated that administration of a combination of rifampin and streptomycin was more efficacious than administration of rifampin alone. A significant reduction in antibody titer was observed when a combination of 15 mg/kg/day of rifampin per os and 15 mg/kg/day streptomycin intramuscularly was used in comparison with the antibody of control group.

Performance Analysis of OFDM M-ary QAM System with One Tap Equalizer in Rummler Fading Channel (룸머 페이딩 환경 하에서 단일 탭 등화기를 사용한 OFDM M-ary QAM 시스템의 성능 분석)

  • 심재옥;김언곤
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.6 no.2
    • /
    • pp.175-180
    • /
    • 2002
  • In this paper, the system performace with the convolution rode using a Viterbi decoding and the one tap LMS(Least Meam Square) equalizer applied to the OFDM(Orthogonal Frequency Division Multiplexing) system, is analyzed through computer simulation. DMRS(Digital Microwave Radio System)is modeled as Rummler fading channel. In Simulation result, we known that the coding system improved about 3.6dB~10.5dB when BER is 10 $^3$and b is 0.1~0.2 in case of 16QAM(Qurdrature Amplitude Modulation). Also, we known that was improved about 19.7dB when the b is 0.1 and was demanded about 10.5dB when the b is 0.2 in case of 64QAM. we known that the soft decision improved about 2~0.9dB when the b is 0.1~0.2 in case of 16QAM and about 3.3~7.8dB in case of 64QAM. In the equalizer system, efficiency improved from the case of that Eb/No is more than 13dB.

A Flash Memory B+-Tree for Efficient Range Searches (효율적 범위 검색을 위한 플래시 메모리 기반 B+-트리)

  • Lim, Sung-Chae;Park, Chang-Sup
    • The Journal of the Korea Contents Association
    • /
    • v.13 no.9
    • /
    • pp.28-38
    • /
    • 2013
  • During the past decades, the B+-tree has been most widely used as an index file structure for disk-resident databases. For the disk based B+-tree, a node update can be cheaply performed just by modifying its associated disk page in place. However, in case that the B+-tree is stored on flash memory, the traditional algorithms of the B+-tree come to be useless due to the prohibitive cost of in-place updates on flash memory. For this reason, the earlier schemes for flash memory B+-trees usually take an approach that saves B+-tree changes from real-time updates into extra temporary storage. Although that approach can easily prevent frequent in-place updates in the B+-tree, it can suffer from a waste of storage space and prolonged search times. Particularly, it is not allowable to process range searches on the leaf node level. To resolve such problems, we devise a new scheme in which the leaf nodes and their parent node are stored together in a single flash block, called the p-node block.

Synthesis and Structure of N-Methylphenazinium-Tetracynnopalladate(II) Hydrate (N-Methylphenazinium-Tetracyanopalladate(II) Hydrate의 합성 및 결정구조 연구)

  • NamGung, Hae;Lee, Hyun-Mi
    • Korean Journal of Crystallography
    • /
    • v.17 no.1
    • /
    • pp.6-9
    • /
    • 2006
  • Crystal structure of Bis(N-Methylphenazinium)-Tetracyanopalladate(II) hydrate has been determined by X-ray crystallography. Crystal data: $(C_{13}H_{11}N_2){_2}[Pd(cn)_4]{\cdot}H_2O$, Monocline, Space group $P2_1/b$(No=14), a=9.783(4), b=10.788(4), c=13.666(4) ${\AA},\;{\beta}=104.59(5),\;Z=2,\;V=1392.9{\AA}{^3},\;Dc=1.476gcm^{-3},\;F(000)=632,\;{\mu}=7.05cm^{-1}$. The structure was solved by Patterson method and refined by full matrix least-square methods using unit weights. The final R and S values were R=0.0257, Rw=0.0732, Rall=0.0283 and S=1.07 for 1930 observed reflections. Both cation and anion complexes are essentially planar and have dihedral angles of $10.16(4)^{\circ}$. The planar complex anions are sandwiched between slightly bent cations. The interplanar separations in one triad and between two triads are 3.419(3) and $3.402(4){\AA}$, respectively. The triads are stacked along b-axis.

Botryococcus sp.의 성장에 미치는 광도와 영양염류의 영향

  • Oh, Hee-Mock;Kim, Seong-Bin;Park, Jun-Hong;Park, Eung-Roh;Lee, Sung-Taik;Kwon, Gi-Seok;Yoon, Byung-Dae
    • Microbiology and Biotechnology Letters
    • /
    • v.25 no.4
    • /
    • pp.339-345
    • /
    • 1997
  • Under the light intensity of 25-72$\mu$E/ m$^{2}$/s Botryococcus braunii UTEX 572 grew faster than Botryococcus sp. GE 24 isolated from a freshwater lake. The specific growth rate ($\mu$) of B. braunii UTEX 572 was highest at 0.260 (1/day) on a dry weight basis in Chu 13 medium from 1 to 9 days of incubation and then continuously decreased. Carbohydrate concentration and cellular nitrogen and phosphorus contents of B. braunii UTEX 572 gradually decreased with light intensity over a range of 25-72$\mu$E/m$^{2}$2/s, whereas the concentrations of protein and cellular N:P ratio increased with light intensity. Chlorophyll-a concentration showed a decreasing tendency with light intensity. The dry weight of B. braunii UTEX 572 increased in the highest rate of 83 mg/l/day at pH 8.0. When the N: P ratio of Chu 13 medium was adjusted to 50: 1 by addition of nitrogen source, dry weight increasing rate was 115 mg/l/day between 20 and 28 days of incubation which was the highest value during the cultivation. Cell growth in an open culture of B. braunii UTEX 572 was highest with Chu 13 medium, whereas that with Chu 13 medium adjusted to pH 7.0, containing 250 mg/l penicillin, or containing 1% glucose was reduced on a large scale. However, this result shows the possibility of the mass cultivation of B. braunii UTEX 572 in an open system competing with other microorganisms.

  • PDF

Physiologic races of Erysiphe graminis f. sp. hordei in Korea (한국 보리흰가루병균(Erysiphe graminis. f. sp. hordei)의 레이스)

  • Woo Hong Du;Kim Ki Chung
    • Korean journal of applied entomology
    • /
    • v.22 no.4 s.57
    • /
    • pp.283-286
    • /
    • 1983
  • Physiologic races of Erysiphe graminis f. sp. hordei were isolated from diseased barley plants collected from 93 locations in Korea, 1980 and 1982. Nine races, 3,8,11,19, J13, K1A, K1B, K2, and K3, were identified by using Cherewick's differential plants. Among them, races K1A, K1B, K 2, and K 3 were firstly recorded by authors in Korea. These races were mainly collected from Jeonnam and Gyeongnam province, whereas race 8 was isolated only in Buan, Jeonbug province. On the other hand, race J 13 previously reported in Japan was prevalent as $36.6\%$ of total isolated races, mostly being isolated in southern region of Korea.

  • PDF

Colonizing Pattern of Fluorescent Pseudomonads on the Cucumber Seed and Rhizoplane (형광성 Pseudomonas屬 균주의 오이 종자처리 후 근권에서의 밀도와 정착양상)

  • Kang, Ji-Hyo;Park, Chang-Suk
    • Korean Journal Plant Pathology
    • /
    • v.13 no.3
    • /
    • pp.160-166
    • /
    • 1997
  • Number of bacterial isolates were collected from high mountainous areas at various locations in the whole country to select promising biocontrol agents. Most of selected isolates belonged to fluorescent pseudomonads. Population densities of fluorescent pseudomonads were examined by DLF method. Alll selected isolates rapidly multiplied on spermosphere after seed inoculation upto 24, and then the population abruptly declined. When seeds were germinated fully, bacteria moved to newly emerging radicle. The good root colonizing isolates, B16 and V13 proliferated on the growing root and moved down to the root tip and lateral roots. but the poor root colonizing isolates, MC07 and X01 moved much slower. Scanning electron microscopic observations showed that the cells of the good colonizing isolates were arranged linearly on the growing root and parallel to growing root axis and continuously existed on the root tip, Whereas the cells of poorly colonizing isolates were gathered and scattered randomly on the root surface.

  • PDF

Antimicrobial activity of fermented Maillard reaction products, novel milk-derived material, made by whey protein and Lactobacillus rhamnosus and Lactobacillus gasseri on Clostridium perfringens

  • Kim, Yujin;Kim, Sejeong;Lee, Soomin;Ha, Jimyeong;Lee, Jeeyeon;Choi, Yukyung;Oh, Hyemin;Lee, Yewon;Oh, Nam-su;Yoon, Yohan;Lee, Heeyoung
    • Animal Bioscience
    • /
    • v.34 no.9
    • /
    • pp.1525-1531
    • /
    • 2021
  • Objective: The objective of this study was to evaluate the antimicrobial effects of fermented Maillard reaction products made by milk proteins (FMRPs) on Clostridium perfringens (C. perfringens), and to elucidate antimicrobial modes of FMRPs on the bacteria, using physiological and morphological analyses. Methods: Antimicrobial effects of FMRPs (whey protein plus galactose fermented by Lactobacillus rhamnosus [L. rhamnosus] 4B15 [Gal-4B15] or Lactobacillus gasseri 4M13 [Gal-4M13], and whey protein plus glucose fermented by L. rhamnosus 4B15 [Glc-4B15] or L. gasseri 4M13 [Glc-4M13]) on C. perfringens were tested by examining growth responses of the pathogen. Iron chelation activity analysis, propidium iodide uptake assay, and morphological analysis with field emission scanning electron microscope (FE-SEM) were conducted to elucidate the modes of antimicrobial activities of FMRPs. Results: When C. perfringens were exposed to the FMRPs, C. perfringens cell counts were decreased (p<0.05) by the all tested FMRPs; iron chelation activities by FMRPs, except for Glc-4M13. Propidium iodide uptake assay indicate that bacterial cellular damage increased in all FMRPs-treated C. perfringens, and it was observed by FE-SEM. Conclusion: These results indicate that the FMRPs can destroy C. perfringens by iron chelation and cell membrane damage. Thus, it could be used in dairy products, and controlling intestinal C. perfringens.

Measurement of Ultrasonic Field Propagation Characteristics in Biological Tissues Using a Two-dimensional Array Hydrophone (2차원 배열 수중청음기를 이용한 생체조직에서의 초음파 음장 전파특성 측정)

  • ;;;;Xiu-Fen Gong
    • The Journal of the Acoustical Society of Korea
    • /
    • v.20 no.5
    • /
    • pp.76-82
    • /
    • 2001
  • Because the biological tissue with inhomogeneous acoustic properties does not keep a particular shape, the measurement of propagation characteristics of ultrasonic fields by the conventional scanning method with a miniature hydrophone is difficult. In this study, a two-dimensional may hydrophone was fabricated using the PVDF (Polyvinylidene fluoride) piezo-electric film and a ultrasonic field measurement system with it was established. For the acoustic field produced by a circular plan transducer with center frequency of 2.25㎒ and 13㎜ in diameter, it was possible to make a fairly accurate field measurement using the hydrophone system. The attenuation coefficients at 2.25 ㎒ for biological tissues were 0.7∼1.3 dB/cm(average; 1.0 dB/cm) in bovine liver, 1.0∼1.8 dB/cm (average; 1.6 dB/cm) in pig liver, 0.9∼2,9 dB/cm(average: 2.1 dB/cm) in bovine muscles, 1.7∼3.3 dB/cm (average; 2.5 dB/cm) in pig muscles.

  • PDF

Antibacterial Substances of the Flower of Chrysanthemum zawadskii Herbich var. latilobum Kitamura (구절초 꽃의 항균성 물질)

  • Jang, Dae-Sik;Park, Ki-Hun;Choi, Sang-Uk;Nam, Sang-Hae;Yang, Min-Suk
    • Applied Biological Chemistry
    • /
    • v.40 no.1
    • /
    • pp.85-88
    • /
    • 1997
  • In orther to isolate antibacterial substances from the flower of Chrysanthemum zawadskii Herbich var. latilobum Kitam., the chloroform fraction was fractionated according to the activity against B. subtilis, S. aureus and V. parahaemolyticus. Two antibacterial substances were isolated and purified by preparative TLC and recrystallization. Compound I showed activity against all the tested bacteria and compound II exhibited the activity against B. subtilis and v. parahaemolyticus except S. aureus. Compared to benzoic acid and sorbic acid which are being used as food preservatives, compounds I and II showed about five-fold stronger antibacterial activity against B. subtilis and V. parahaemolyticus. On the basis of spectrometric studies including $^1H-NMR,\;^{13}C-NMR,\;DEPT,\;^1H-^1H\;COSY,\;^{13}C-^1H\;COSY$ and Mass, compounds I and II were identified as angeloylcumambrin B and cumambrin A, respectively. This is the first report of the isolation of angeloylcumambrin B and cumambrin A from this plant.

  • PDF