• 토지주택연구
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• 제4권1호
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• pp.125-131
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• 2013

얕은 기초 설계와 시공을 위해 실시하는 평판재하시험 결과로부터 실제 기초지반의 침하량을 산정하고 있는데 국내에서 많이 시공되는 화강풍화토나 풍화암에 대한 현장 예측식이 없는 실정이다. 따라서, 본 연구에서는 화강풍화토와 풍화암을 대상으로 현장 평판 재하시험을 실시하여 기초 크기별 침하량 거동을 분석하였다. 모형토조와 현장 재하시험에서 측정한 하중 ~ 침하 곡선을 일반적인 항복하중 판정법을 사용하지 않고 하중 ~ 상대침하(s/B, s : 침하량, B : 재하판폭) 관계로 정규화(Normalization)하여 분석하였다. 즉, 하중 ~ 상대 침하 개념으로 정규화한 결과, 재하판 직경에 관계없이 일정한 형태의 곡선을 나타내므로 현장의 지반조건과 상관성을 제시하였다.

• 한국수학교육학회지시리즈B:순수및응용수학
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• 제27권3호
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• pp.125-135
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• 2020

In this paper, we investigate the properties of Alexandrov topologies, non-symmetric pseudo-metrics and lower approximation operators on [0, ∞]. Moreover, we investigate the relations among Alexandrov topologies, non-symmetric pseudo-metrics and lower approximation operators. We give their examples.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2005년도 동계학술연구발표회 및 2차 아시안포럼
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• pp.125-125
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• 2005

• 한국수학교육학회지시리즈B:순수및응용수학
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• 제29권2호
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• pp.125-139
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• 2022

In this paper we wish to establish some results relating to the growths of composition of two entire functions with their corresponding left and right factors on the basis of their generalized relative order (α, β) and generalized relative lower order (α, β) where α and β are continuous non-negative functions defined on (-∞, +∞).

• Journal of Digestive Cancer Research
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• 제5권2호
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• pp.105-112
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• 2017

위암 발병에 관여하는 Helicobacter pylori는 위상피세포내에서 많은 miRNA의 변화를 유도하여 발암과정에 역할을 할 것으로 추정하고 있다. 현재까지 H. pylori 감염 시 상피세포에서 miRNA 변화에 대해 명확히 밝혀져 있지 않다. 본 연구의 목적은 H. pylori에 감염된 위상피세포에서 miRNA의 발현 변화를 관찰하고자 하였다. H. pylori에 6시간 동안 감염시킨 AGS 위상피세포주와 AGS 세포주에 3개월 이상 장기간 H. pylori를 감염시켜 얻은 세포주(HS3C)를 대상으로 하였다. 대상 세포주로 부터 miRNA만을 분리한 후, custom microarray를 이용하여 발현 변화를 관찰하였다. 또한 microarray에서 유의한 증감이 관찰된 목표 유전자를 선별하여 real-time PCR을 이용하여 정량적 변화를 확인하였다. miRNA microarray 분석 결과를 토대로 변화가 관찰된 12개의 miRNA를 선별하였다. Real-time PCR 검사로 miRNA의 변화를 검정한 결과, miR-21, miR-221, miR-222은 6시간 동안 감염시킨 AGS 위상피세포주와 HS3C 세포주 모두에서 증가되어 있었다. miR-99b, miR-200b, miR-203b, miR-373은 6시간 동안 감염시킨 AGS 위상피세포주와 HS3C 세포주 모두에서 감소되어 있었다. miR-23a, miR-23b, miR-125b, miR-141, miR-155는 H. pylori에 6시간 동안 감염된 AGS 위상피세포주에서 감소되었으나, HS3C에서는 증가되어 있었다. H. pylori 감염 위상피세포주에서 miR-21, miR-99b, miR-125b, miR-200b, miR-203b, miR-221, miR-222, miR-373의 발현 변화는 위암의 발생기전에 관여할 것으로 추정되며, 각각의 기능과 역할의 규명에 대해서는 후속 연구가 필요하다.

• 대한기계학회논문집B
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• 제32권2호
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• pp.125-132
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• 2008

The bubble dynamics and heat transfer associated with nucleate boiling in parallel microchannels is studied numerically by solving the equations governing conservation of mass, momentum and energy in the liquid and vapor phases. The liquid-vapor interface is tracked by a level set method which is modified to include the effects of phase change at the interface and contact angle at the wall. Also, the reversible flow observed during flow boiling in parallel microchannels has been investigated. Based on the numerical results, the effects of contact angle, wall superheat and the number of channels on the bubble growth and reversible flow are quantified.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2010년도 하계학술대회 논문집
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• pp.125-125
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• 2010

The Hybrid Fault current limit combined the semiconductor switching components, for example IGBT, with mechanical fast switch reduced mechanical and thermal stress on electrical machines, for example circuit breaker, transformer, and so on, in the electric network. We had focused on reducing the voltage stress of the semiconductor switching components by the mechanical fast switch. As a result, we could dramatically reduce amount of semiconductor switching components only using parallel arrangement of them, not series.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2003년도 봄 학술발표회 논문집
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• pp.1091-1096
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• 2003

Pullout tests of single headed bars using plain concrete blocks indicate that the embedment depth of $10d_b$ is in general required for the headed bars to develop pullout strength equivalent to 125% of bar yield strength. In this experimental study, test results of multiple headed bars installed in reinforced concrete column sections are presented. Test variables included embedment depth, column main reinforcement ratio, and spacing of column ties. 2D29 bars were pulled out at one time from normal strength concrete. Test results indicated that the embedment depths, column tie spacings, and column main reinforcement ratios all influenced the pullout strengths of the headed bars. When the embedment depth was not sufficient, narrow tie spacings especially resulted in increased pullout strengths of the headed bars. Test results also indicated that the embedment depth of 15㏈ was sufficient for the closely spaced two headed bars (head-to-head spacing =$6d_b$) to develop pullout strength equivalent to 125% of the bar yield strength.

• 대한기계학회논문집B
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• 제31권2호
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• pp.125-131
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• 2007

This paper presents guideline for a practical design of the hybrid system combining a pressurized solid oxide fuel cell and a gas turbine. Design of the hybrid system based on a virtually designed gas turbine was simulated using models for off-design operation of the gas turbine. Two system configurations, with different method for supplying reforming steam, are considered and their design characteristics are compared. A higher design cell temperature provides better system performance. However, there exists a maximum allowable design cell temperature because the operating point of the compressor approaches the surge point with increasing fuel cell temperature. Increased pressure loss at the fuel cell moves the compressor operating point toward the surge point and reduces system performance.

• Archives of Pharmacal Research
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• 제27권1호
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• pp.77-82
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• 2004

DA-125, a novel derivative of adriamycin, is known for its anti-cancer activity. In this study, the inhibitory mechanism of DA-125 on topoisomerase was investigated in the simian virus 40 (SV40) replicating CV-1 cell by studying the SV40 DNA replication intermediates and DNA-topoisomerase complexes. DNA-protein complexes that were formed in the drug-treated cells were quantitated by using a glass filter assay. SV40 DNA replication intermediates that were accumulated in the drug-treated CV-1 cell were analyzed in a high resolution gel. DA-125 did not accumulate B-dimers of SV40 DNA replication intermediates which were found in the adriamycin-treated CV-1 cells. DA-125 induced a dose-dependent formation of the DNA-protein complexes, while adriamycin did not. When adriamycin and etoposide (VP16) were added to the SV40-infected cells at the same time, adriamycin blocked the formation of the DNA-protein complexes induced by VP16 in a dose-dependent manner. However, DA-125 blocked the formation of the DNA-protein complexes induced by VP16 up to the maximum level of the DNA-protein complexes that were induced by DA-125 alone. Adriamycin and DA-125 did not inhibit the formation of the DNA-protein complexes that were caused by camptothecin, a known topoisomerase I poison. DA-125 is bifunctional in inhibiting topoisomerase II because it simultaneously has the properties of the topoisomerase II poison and the DNA intercalator. As a topoisomerase II poison, DA-125 alone induced dose-dependent formation of the DNA-protein complexes. However, as a DNA intercalator, it quantitatively inhibited the formation of the DNA-protein complexes induced by a strong topoisomerase II poison VP16. Furthermore considering that the levels of the DNA-protein complex induced by VP16 were decreased by DA-125 in terms of the topoisomerase II poison, we suggest that DA-125 has a higher affinity to the drug-binding sites of DNA than VP16 has.