• Journal of Applied Biological Chemistry
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• v.62 no.2
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• pp.111-122
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• 2019

The mulberry tree (Morus alba L.) has been traditionally used in Chinese medicine to treat inflammatory diseases. We investigated the effects of bioconversion on different components of the mulberry tree, and determined changes in the physiological activities. Ethyl acetate-soluble fractions of five different segments (fruit, Mori Fructus; leaf, Mori Folium; twig, Mori Ramulus; root, Mori Cortex; and mistletoe, Loranthi Ramulus) of the mulberry tree show enhanced anti-oxidant effects in the 2,2-diphenyl-1-picrylhydrazyl, and 2,2'-azinobis-(3-ethylvenzothiazoline-6-sulfonic acid) assays, and enhanced anti-inflammatory effects of lipopolysaccharide (LPS)-stimulated nitric oxide (NO) production in RAW 264.7 macrophages, after being treated with a crude enzyme extract from Aspergillus kawachii, in the following order of activity: Mori Folium>Mori Cortex>Mori Ramulus>Mori Fructus>Loranthi Ramulus. Ethyl acetate- soluble fraction of mulberry leaves (Mori Folium) that underwent bioconversion was most effective, and was devoid of any cytotoxicity. The fraction was also effective against mRNA expression of LPS-induced pro-inflammatory cytokines, such as inducible nitric oxide synthase, cyclooxygenase-2, tumor necrosis $factor-{\alpha}$, $interleukin-1{\beta}$, and interleukin-6. In addition, the fraction was effective in LPS-induced phosphorylation of mitogen-activated protein kinases and IKK, and $I{\kappa}B$ degradation, followed by translocation of the nuclear $factor-{\kappa}B$ from the cytoplasm to the nucleus. Thus, bioconversion increased the anti-oxidative and anti-inflammatory activities of the mulberry leaf.

• Journal of Korean Society of Forest Science
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• v.84 no.4
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• pp.409-414
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• 1995

This study was carried out for the analysis and comparison about the noise diminution effects by the height, width and density of Euonymus japonica wall, the distance of sound source, the distance of sound receiver, the height of sound source, and the height of sound receiver. The results obtained were summarized as follows; 1. After the establishment of tree wall, the volume of noise diminution measured 6.8dB and the effects of noise diminution measured heigher than before by 10.6% and t-value was significant at the 1% level 2. In simple correlation between the effects of noise diminution and variables, the density of tree wall was found as the most significant factor, and the last were found in the order of the distance of sound receiver, the width of tree wall, and the distance of sound source. 3. In partial correlation coefficients the effects of noise diminution and variables, the density of tree wall (r=-0.959) was found as the most significant factor, and the last were found in order of the distance of sound receiver (r=-0.906) and the width of tree wall (r=-0.753). 4. The estimated equation to measure the effects of noise diminution according to variables (the height of tree wall, the width of tree wall, the density of tree wall, the distance of sound source, the distance of sound receiver, the height of sound source, and the height of sound receiver) was $Y=69.520-1.672X_1-1.656X_2-0.066X_3-0.248X_4-3.134X_5-0.222X_6-0.343X_7$, and the coefficient of determination of this estimated equation was highly found as 0.950. 5. In semi-partial correlation coefficient the effects of noise diminution were found in the order of the density of tree wall, the distance of sound receiver, the width of tree wall, and the height of tree wall from the highest to the lowest. Therefore, it was considered that the density of tree wall, the distance of sound receiver, the width of tree wall and the distance of sound source should be controlled effectively to increase the effects of noise diminution by Euonymus japonica wall.

• Korean Journal of Computational Design and Engineering
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• v.1 no.1
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• pp.20-32
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• 1996

The boundary evaluation technique for Boolean operation on non-manifold models which is regarded as the most popular and powerful method to create and modify 3-D CAD models has been developed. This technique adopted the concept of Merge and Selection in which the CSG tree for Boolean operation can be edited quickly and easily. In this method, the merged set which contains complete information about primitive models involved is created by merging primitives one by one, then the alive entities are selected following the given CSG tree. This technique can support the hybrid representation of B-rep(Boundary Representation) and CSG(Constructive Solid Geometry) tree in a unified non-manifold model data structure, and expected to be used as a basic method for many modeling problems such as data representation of form features, and the interference between them, and data representation of conceptual models in design process, etc.

• Proceedings of the KAIS Fall Conference
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• 2009.12a
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• pp.618-621
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• 2009

데스크탑 및 이동형 컴퓨터의 저장 장치를 지원하는 플래시 메모리는 비휘발성, 낮은 전력소모, 빠른 데이터 접근 속도 등의 장점이 있다. 하지만, 일반 RAM 메모리에 비하여 상대적으로 느린 연산 특성을 고려하여 기존의 전통적인 인덱스 관리 기법을 개선할 필요가 있다. 이를 위하여, 본 논문은 CHC-Tree 라고 하는 압축된 핫-콜드 클러스터링에 기반하는 새로운 인덱스 관리 기법을 제안한다. CHC-Tree는 인덱스 노드를 핫-콜드 세그먼트로 분류하며, 인덱스 노드의 키와 포인터를 압축한다. 또한, 실험 결과를 통하여 기존의 B-Tree 기반의 인덱스 관리 기법보다 인덱스 검색 및 인덱스 수정 연산에서 더 우수함을 확인하였다.

• Journal of Industrial Technology
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• v.26 no.B
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• pp.145-155
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• 2006

High level of reliability in facility operation is specifically required these days. The goal of this study is to secure a methodology for reliability analysis of hydro-power plant so that an appropriate decision for operation and investment can be made. Fault tree analysis of water supply system within hydro-power plant has been performed in this study. We briefly examined the electric power generation facility and water supply system. We then developed fault tree for the water supply system based on failure modes and effects analysis. We conclude this study and provided future research areas.

• Proceedings of the Korean Information Science Society Conference
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• 2004.04b
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• pp.124-126
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• 2004

최근 인터넷 상에서 정보 양이 증대함에 따라 DTD 기반의 XML을 이용하여 방대한 정보를 효율적으로 저장하고 검색하기 위한 많은 연구들이 진행되고 있다 하지만 DTD의 문서를 작성에는 많은 노력이 필요하고, 문서 구조의 검사가 필요 없는 간단한 문서만 사용하는데 있어서 DTD 작성은 불필요한 작업이 아닐 수 없다. 하지만 DTD 문서가 없을 경우에도 XML 기본 문법만 맞으면 문서를 파싱할 수 있고, 불필요한 네트？ 부담을 줄이기 위해 DTD없이 전송한 수 있다. 따라서 본 연구에서는 DTD가 없는 Well-Formed XML 문서를 구성하는 엘리먼트의 구조를 통해 정보를 추출하고, 주기억장치의 효율적인 저장 공간을 활용한 CS$B^{＋}$-Tree 인덱스를 이용하여 Well-formed XML 문서를 저장하기 위한 기법을 제안한다.

• Proceedings of the Korean Society of Computer Information Conference
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• 2019.07a
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• pp.383-384
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• 2019

본 논문에서는 이더리움 기반 블록체인 확장성 문제해결을 위해 데이터 저장방법인 Merkle patricia tree를 응용하여 데이터에 따라 트리 이원화 사용을 제안한다. 이 연구는 시스템 자원인 CPU와 메모리를 효율적으로 사용하여 트랜잭션 처리량을 최대화하고, 작업시간을 최소화하기 위함이다. 본 논문에서는 기존 이더리움 블록체인의 트랜잭션 처리속도와 확장성 향상을 목표로 하며. 기존의 방식과 비교하여 제안을 분석한다.

• Bulletin of the Korean Mathematical Society
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• v.60 no.5
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• pp.1375-1390
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• 2023

In this note, we shall show that the generalized free products of subgroup separable groups amalgamating a subgroup which itself is a finite extension of a finitely generated normal subgroup of both the factor groups are weakly potent and cyclic subgroup separable. Then we apply our result to generalized free products of finite extensions of finitely generated torsion-free nilpotent groups. Finally, we shall show that their tree products are cyclic subgroup separable.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.43 no.4
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• pp.357-364
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• 2017

The aim of this study is to investigate the effect of Hovenia dulcis (oriental raisin tree) extract on ganodermanondiol (GN) contents in Ganoderma lucidum (G. lucidum) mycelia. GN has a triterpenoid structure and is one of the major active components of G. lucidum. Furthermore, we previously proved its inhibitory effects on tyrosinase activity and melanin biosynthesis in B16F10 melanoma cells. In this study, we observed significantly increased GN contents in G. lucidum mycelial extracts supplemented with 15% (v/v) oriental raisin tree extract (ORTE) by HPLC analysis. In addition, melanogenesis was significantly inhibited by G. lucidum extract supplemented with 15% ORTE when compared to G. lucidum extract without ORTE supplementation. Furthermore, mycelial growth of G. lucidum was increased by ORTE supplementation in both solid and liquid cultivation. These results suggest that the oriental raisin tree is useful as natural ingredient for increasing GN biosynthesis as well as whitening effect of G. lucidum.

• Genes and Genomics
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• v.40 no.11
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• pp.1181-1197
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• 2018

Tropical plant rubber tree (Hevea brasiliensis) is the sole source of commercial natural rubber and low-temperature stress is the most important limiting factor for its cultivation. To characterize the gene expression profiles of H. brasiliensis under the cold stress and discover the key cold stress-induced genes. Three cDNA libraries, CT (control), LT2 (cold treatment at $4^{\circ}C$ for 2 h) and LT24 (cold treatment at $4^{\circ}C$ for 24 h) were constructed for RNA sequencing (RNA-Seq) and gene expression profiling. Quantitative real time PCR (qRT-PCR) was conducted to validate the RNA-Seq and gene differentially expression results. A total of 1457 and 2328 differentially expressed genes (DEGs) in LT2 and LT24 compared with CT were respectively detected. Most significantly enriched KEGG pathways included flavonoid biosynthesis, phenylpropanoid biosynthesis, plant hormone signal transduction, cutin, suberine and wax biosynthesis, Pentose and glucuronate interconversions, phenylalanine metabolism and starch and sucrose metabolism. A total of 239 transcription factors (TFs) were differentially expressed following 2 h or/and 24 h of cold treatment. Cold-response transcription factor families included ARR-B, B3, BES1, bHLH, C2H, CO-like, Dof, ERF, FAR1, G2-like, GRAS, GRF, HD-ZIP, HSF, LBD, MIKC-MADS, M-type MADS, MYB, MYB-related, NAC, RAV, SRS, TALE, TCP, Trihelix, WOX, WRKY, YABBY and ZF-HD. The genome-wide transcriptional response of rubber tree to the cold treatments were determined and a large number of DEGs were characterized including 239 transcription factors, providing important clues for further elucidation of the mechanisms of cold stress responses in rubber tree.