• Korean Journal of Food Science and Technology
• /
• v.17 no.3
• /
• pp.192-196
• /
• 1985

Eight strains of Lactobacilli(a, b, b', c, d, e, f and g) were isolated from seven Korean liquid-yogurts(A, B, C, D, E, F and G), and identification and tolerance-test to digestive fluids were carried out. Isolate a from yogurt A and isolate a from yogurt E were identified as L. casei, isolate b from yogurt B as L. acidophilus, isolate d from yogurt D as L. bulgaricus, isolate f from yogurt F as L. helveticus, and isolate b' from yogurt B, isolate c from yogurt C and isolate g from yogurt G as L. jugurti, respectively. Isolate f(L. helveticus) and c(L. jugurti) showed high tolerance to artificial gastric juice but didn't to bile acid. Isolate b(L. acidophilus), a(L. casei), and e(L. casei) showed high tolerance to both artificial gastric juice and bile acid, but isolate d(L. bulgaricus), b'(L. jurgurti) and g(L. jugurti) did not.

• Journal of Microbiology and Biotechnology
• /
• v.25 no.12
• /
• pp.1997-2006
• /
• 2015

Ginsenoside Rg3 is a bioactive ginseng constituent that has been reported to have diverse pathological and physiological effects, including anti-inflammatory and anti-metastatic activities. Metastasis is one of the most important factors involved in patients with melanoma. However, the molecular mechanism underlying the anti-metastatic activities of Rg3 in malignant melanoma cancer has not been fully elucidated. In this study, we have evaluated that Rg3 effectively inhibits metastasis of B16F10 melanoma cancer cells. We found that Rg3 significantly suppresses the migration, invasion, wound healing, and colony-forming abilities of B16F10 cells in a dose-dependent manner. Mechanistically, we demonstrate that Rg3 suppresses B16F10 cell metastasis by inhibiting MMP-13 expression. These results indicate that Rg3 suppresses the metastasis of B16F10 mouse melanoma cancer cells via MMP-13 regulation. Importantly, MMP-13 downregulation may influence the migration and invasion capabilities of melanoma cells and has been correlated with melanoma progression. Therefore, Rg3 is a potential therapeutic candidate that could be used to treat patients with metastatic melanoma.

• The Korean Journal of Physiology and Pharmacology
• /
• v.16 no.4
• /
• pp.265-271
• /
• 2012

HoxB4, a homeodomain-containing transcription factor, is involved in the expansion of hematopoietic stem cells and progenitor cells in vivo and in vitro, and plays a key role in regulating the balance between hematopoietic stem cell renewal and cell differentiation. However, the biological activity of HoxB4 in other cells has not been reported. In this study, we investigated the effect of overexpressed HoxB4 on cell survival under various conditions that induce death, using the Ba/F3 cell line. Analysis of phenotypical characteristics showed that HoxB4 overexpression in Ba/F3 cells reduced cell size, death, and proliferation rate. Moreover, the progression from early to late apoptotic stages was inhibited in Ba/F3 cells subjected to HoxB4 overexpression under removal of interleukin-3-mediated signal, leading to the induction of cell cycle arrest at the G2/M phase and attenuated cell death by Fas protein stimulation in vitro. Furthermore, apoptotic cell death induced by doxorubicin-treated G2/M phase cell-cycle arrest also decreased with HoxB4 overexpression in Ba/F3 cells. From these data, we suggest that HoxB4 may play an important role in the regulation of pro-B cell survival under various apoptotic death environments.

• Korean Journal of Optics and Photonics
• /
• v.6 no.3
• /
• pp.201-213
• /
• 1995

By the use of computer simulation including collisional mixing kinetic processes of the B- and C-state in the upper laser level the output characteristics of electron-beam pumped XeF$(C\rightarrowA$ excimer laser are analyzed. We compared the results between experiments and simulations for the $XeF^*(C)$ formation that correlated the number of densities of the $XeF^*(B)$. We obtained good agreement$(28.5 mJ\pm5%)$ with comparisons between experiment and simulation and confirmed the optimal gas mixing ratio of $Xe/F_2/Ar=5.26/0.49/94.28%$ at atmospheric pressure laser medium under the condition of 70 ns [FWHM] electron-beam (800 kV, 21 kA). Also through the simulation we have investigated that the $XeF^*(C)$ formation channel, the $XeF^*(C)$ relaxation channel, and the absorption channel of bluegreen wavelength region as a function of F2 halogen donor and Xe partial pressure. ssure.

• Applied Chemistry for Engineering
• /
• v.9 no.3
• /
• pp.372-376
• /
• 1998

Supported Pd($Pd/AlF_3$, $Pd/{\gamma}-Al_2O_3$) catalysts and solid-acid catalysts(${\gamma}-Al_2O_3$, ${\alpha}-Al_2O_3$, $AlF_3$) were used to perform dechlorination of HCFC-142b(1-chloro-1,1-difluoroethane) in the presence of excess hydrogen. In the reactions the effects of reaction temperature, the mole ratio(r) of $H_2$ to HCFC-142b and the amount of supported Pd on dechlorination of HCFC-142b into HFC-143a(1,1,1-trifluoroethane) or HFC-152a(1,1-difluoroethane) were investigated. The experimental results showed that the conversion of HCFC-142b to product gases were 60% and 92%, respectively, and the selectivity to HFC-143a in the product gases were 58% and 64% for $Pd/AlF_3$ and $Pd/{\gamma}-Al_2O_3$ catalysts, respectively. On these catalysts an optimum reaction condition was found at $200^{\circ}C$ with the space time of reactant gases as 1.05 second and the mole ratio of $H_2$ to HCFC-142b as 3. Solid-acid catalysts were also tested at the same reaction condition. The results showed that the conversions of HCFC-142b to product gases were 12%, 8% and 7%, and the selectivities to HFC-152a were 94%, 92% and 90% for ${\gamma}-Al_2O_3$, ${\alpha}-Al_2O_3$ and $AlF_3$ catalysts, respectively.

• Journal of the Korean Society for Industrial and Applied Mathematics
• /
• v.5 no.1
• /
• pp.35-45
• /
• 2001

In this paper we point out an Ostrowski type inequality for the Riemann-Stieltjes integral ${\int}_a^b$ f (t) du (t), where f is of p-H-$H{\ddot{o}}lder$ type on [a,b], and u is of bounded variation on [a,b]. Applications for the approximation problem of the Riemann-Stieltjes integral in terms of Riemann-Stieltjes sums are also given.

• Journal of the Chungcheong Mathematical Society
• /
• v.27 no.4
• /
• pp.697-705
• /
• 2014

For a complex measure ${\mu}$ on B and $f{\in}L^2_a(B)$, the Toeplitz operator $T_{\mu}$ on $L^2_a(B,dv)$ with symbol ${\mu}$ is formally defined by $T_{\mu}(f)(w)=\int_{B}f(w)\bar{K(z,w)}d{\mu}(w)$. We will investigate properties of the Toeplitz operator $T_{\mu}$ with symbol ${\mu}$. We define the Toeplitz type operator $T^r_{\psi}$ with symbol ${\psi}$, $$T^r_{\psi}f(z)=c_r\int_{B}\frac{(1-{\parallel}w{\parallel}^2)^r}{(1-{\langle}z,w{\rangle})^{n+r+1}}{\psi}(w)f(w)d{\nu}(w)$$. We will also investigate properties of the Toeplitz type operator with symbol ${\psi}$.

• Honam Mathematical Journal
• /
• v.15 no.1
• /
• pp.75-85
• /
• 1993

For A and B, $-1{\leq}B<A{\leq}1$, let P[A, B] be the class of functions p analytic in the unit disk E with P(0) = 1 and subordinate to $\frac{1+Az}{1+Bz}$. We introduce the class $T_{\alpha}[A,B]$ of functions $f:f(z)=z+\sum\limits_{n=2}^{{\infty}}a_nz^n$ which are analytic in E and for $z{\in}E$, ${\alpha}{\geq}0$, $[(1-{\alpha}){\frac{f(z)}{z}}+{\alpha}f^{\prime}(z)]{\in}P[A,B]$. It is shown that, for ${\alpha}{\geq}1$, $T_{\alpha}[A,B]$ consists entirely of univalent functions and the radius of univalence for $f{\in}T_{\alpha}[A,B]$, $0<{\alpha}<1$ is obtained. Coefficient bounds and some other properties of this class are studied. Some radii problems are also solved.

• The Journal of the Korea Contents Association
• /
• v.2 no.4
• /
• pp.93-98
• /
• 2002

Functional equations are useful in the experimental science because they play very important role for researchers to formulate mathematical models in general terms, through some not very restrictive equations that only stipulate basic properties of functions showing in these equations, without postulating the exact forms of such functions. Of lots of such functional equations, in this paper we adopt and solve some generalized quadratic functional equation a$^2$f((x+y/a))+b$^2$f((x-y/b)) = 2f(x)+2f(y)

• Communications of the Korean Mathematical Society
• /
• v.12 no.3
• /
• pp.701-707
• /
• 1997

In [8], we introduce the relative root Nielsen number N(f;X, A, c) for maps of pairs of spaces $f : (X, A) \to (Y, B)$. From it, we obtain some immediate consequences of the definition and illustrate it by some examples. We consider the question whether there exists a map $g : (X, A) \to (Y, B)$ homotopic to a given map $f : (X, A) \to (Y, B)$ which has precisely N(f;X, A, c) roots, that is, the minimum theorem for N(f;X, A, c).