• Clinical and Experimental Reproductive Medicine
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• 제40권3호
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• pp.115-121
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• 2013

Objective: Letrozole and estradiol valerate are used to treat some hormonally-responsive symptoms and also in modeling of the polycystic ovary syndrome. However, the stereological analysis of the ovary has received less attention. Estimation of the whole ovary volume using the Cavalieri method can be applied in any orientation desired, but estimation of the mean volume of the oocytes requires isotropic uniform random sectioning. Here, a combined method was developed for estimating the parameters. To our knowledge, no comparison has been made of the effects of letrozole and estradiol on the ovary. Methods: Sixty rats were divided into 4 groups receiving estradiol (4 mg/kg), olive oil, letrozole (1 mg/kg), or normal saline. After 21 days, their ovaries were studied. Results: Relative to the control group, the total volume of the ovary and the cortex increased in the letrozole-treated and estradiol-treated rats. In addition, the number of the preantral, antral, and granulosa cells decreased by 43% to 56% in the letrozole- and estradiol-treated rats. On average, a 19% increase was observed in the atretic oocytes of the letrozole-treated and estradiol-treated rats, but the mean oocyte volume decreased by 29% to 44% in letrozole- and estradiol-treated rats. Furthermore, the letrozole-treated rats showed a 5-fold and 7-fold increase in the volume of the cysts and corpus luteum, respectively. A 3-fold increase was found in the volume of both the cysts and corpus luteum in the estradiol group. Conclusion: The structural changes of the ovary were most pronounced in the letrozole-treated animals.

• 한국지하수토양환경학회지:지하수토양환경
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• 제22권4호
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• pp.1-8
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• 2017

Efficient groundwater management requires accurate information about the water volume used. The pumped volume of groundwater can be indirectly estimated using empirical formulae based on electric power consumption. The purpose of this study is to test the accuracy of this indirect method. The Haean basin in Gangwon is located in a rural area, where majority of the groundwater extracted is used for irrigation. The pumped volume of groundwater indirectly estimated from electricity usage using these empirical formulae was compared with the actual pumped volume determined by conducting experiments on April 29 and May 19, 2017. The field survey collected data on electricity usage, pumped volume, and groundwater levels. Based on this measured data, correlations were calculated between electricity usage and pumping volume, as well as groundwater level and pumping rate. The results show that electricity usage and pumped volume measured for both wells (YHE1 and YHE2) are highly correlated (r=0.99, p<0.001). However, for YHE1, notably, the correlation between the groundwater level and pumping rate was not significant, and only some correlations were identified for these variables for the YHE2 test well. The average error with respect to the estimation of the actual pumped volume from the existing formula (1) and formulae (2) and (3) are +399% and -88%, respectively. To reduce these errors, these formulae need to consider other factors affecting the pumped volume.

• Journal of Radiation Protection and Research
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• 제22권3호
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• pp.183-193
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• 1997

원전 작업자 피폭관리와 안전성 평가 및 최종적으로 처분허가를 위하여 폐기물 내의 핵종 및 농도를 파악하여야만 한다. 이온교환 수지 및 필터는 그 부피는 작으나 원전 운전중 발생하는 폐기물 내 방사능의 대부분을 차지하고 있다. 본 연구의 목적은 냉각수 정화 계통내의 수지 및 필터 내에 누적되어 있는 방사성 핵종의 양을 예측할 수 있는 방법을 개발하는 것이다. 핵종누적량을 계산하기 위하여 평균제염계수 대신 순간제염계수를 사용하였으며 포트란언어를 사용하여 프로그램을 작성하여 누적량을 계산하였다. 본 예측기법의 검증을 위하여 미국 Rancho-Seco 발전소의 측정자료를 이용하였으며 실험을 통한 계측자료를 검증에 이용하였다. 순간제염계수를 이용한 본 방법의 계산이 평균제염계수를 이용한 것보다 오차가 작았다. 이 방법을 실제 적용하기 위해서는 운전지침에 의하여 주기적으로 계측한 제염제수와 핵종농도 자료만으로도 핵종누적량 계산이 가능하다. 그러나, 특히 발전소 운전상황이 급격하게 변할 때에는, 정확한 누적량 평가를 위하여 제염계수 및 방사성 핵종농도의 측정주기가 짧아져야 한다.

• 한국전자파학회논문지
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• 제24권2호
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• pp.189-197
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• 2013

전자 통신 기술의 발전 추세에 따라 유비쿼터스 환경이 구축되면서 일상 생활에서 전자 기기의 밀집도는 폭발적으로 증가하는 추세를 보이고 있다. 이러한 다양한 전자 기기들이 ICT 건물 등의 사회 기반 시설에 설치될 시 이들 사이의 전자파 적합성 및 간섭 분석과 파악을 위해서는 효율적이고도 빠른 대형 구조물의 전자파 해석기법이 필수적이다. 이에 본 논문에서는 이러한 전자파 해석을 위하여 확률론적 기반의 PWB(Power Balance Method) 해석 방법을 소개하고 그 유용성을 고찰한다. 기존의 맥스웰 방정식에 입각한 결정론적 해석 결과와의 관계를 제시하기 위해 손실이 존재하는 2차원 직각 캐비티(cavity)에서 시뮬레이션을 수행하여, PWB 방법의 기저에 깔린 가정 및 통계적인 결과가 하나의 결정론적 문제에서 필드 분포의 부피 평균(volume average)에 해당함을 보였다. 복잡한 대형 구조물에서 full-wave 전자파 해석이 계산 비용과 시간적인 측면에서 큰 한계점이 있음은 이미 자명한 사실이므로, 통계적인 개념에 기반을 둔 본 PWB 해석 방법이 대형 구조물의 전자파 해석에 있어서 충분히 현실적인 대안이 될 것이다.

• 한국컴퓨터산업학회논문지
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• 제5권9호
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• pp.1005-1016
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• 2004

기존 교통신호등은 최적 교통신호주기기능을 상실했다. 기존 교통신호주기는 현시 교통주기와 30% -45% 가 일치하지 않고 있다. 본 논문에서는 평균 주행속도를 개선하고 평균 승용차 대기시간을 단축하기위해서 전자 교통신호등을 본 논문에서 제안한다. 본 논문에서는 실제 교통상황의 교통량, 출발 지연시간, 자동차속도 등의 40가지 센서 입력조건들을 저장하는 방법을 연구 중이다. 지능형 퍼지 기법을 이용하면, 서로 다른 10개의 교차로에 서 최 적의 녹색시간을 예측할 수 있다. 컴퓨터 모의실험 결과, 자동차 길이를 고려하지 않은 기존 교통신호등보다 . 오프셋 및 평균 자동차 대기시간을 줄일 수 있음이 입증되었다.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2003년도 가을 학술논문집
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• pp.696-700
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• 2003

$H_2SO_4$과 Citric acid 은 다른 화학물질보다 토양으로부터 $^{137}Cs$의 추출효율이 높았다. 오래 저장된 방사능오염 토양으로부터 $^{137}Cs$ 제거효율을 높이기 위해 동전기방법에 의한 토양복원 실험 시 $H_2SO_4$과 citric acid를 첨가제로 사용했다. 실험 컬럼으로부터 방출된 방출수의 평균속도는 $2.0{\times}10^{-2}$cm/min이고, 10일 동안 방출된 토양폐액의 부피는 3.6 Pore Volume이다. 10일간 컬럼 내의 $^{137}Cs$의 제거효율이 54%이었다. 한편, 개발된 모델에 의해 계산된 잔류농도 예측 값은 실험으로부터 구한 결과와 거의 일치했다.

• 대한의용생체공학회:의공학회지
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• 제24권4호
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• pp.247-257
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• 2003

This paper proposes a three-dimensional (3D) segmentation algorithm for extracting a diagnostic object from ultrasound images by using a LoG operator In the proposed algorithm, 2D cutting planes are first obtained by the equiangular revolution of a cross sectional Plane on a reference axis for a 3D volume data. In each 2D ultrasound image. a region of interest (ROI) box that is included tightly in a diagnostic object of interest is set. Inside the ROI box, a LoG operator, where the value of $\sigma$ is adaptively selected by the distance between reference points and the variance of the 2D image, extracts edges in the 2D image. In Post processing. regions of the edge image are found out by region filling, small regions in the region filled image are removed. and the contour image of the object is obtained by morphological opening finally. a 3D volume of the diagnostic object is rendered from the set of contour images obtained by post-processing. Experimental results for a tumor and gall bladder volume data show that the proposed method yields on average two times reduction in error rate over Krivanek's method when the results obtained manually are used as a reference data.

• 한국임상약학회지
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• 제12권1호
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• pp.7-12
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• 2002

Pharmacokinetic parameters and dosage of aminoglycosides (AGs) were studied retrospectively in 36 patients with neutropenic fever after stem cell transplantation in Seoul National University Hospital from July 1996 to June 2001. AGs pharmacokinetic parameters were calculated with steady-state peak and trough serum drug concentrations by the method of Sawchuk and Zaske et at. The calculated aminoglycosides volume of distribution and clearance were greater than population value $(0.36\pm0.06\;L/kg,\;116\pm32\;ml/min/1.73\;m^2,\;respectively)$. The average dosage of aminoglycosides required to maintain optimal serum AGs concentration was also greater than recommended dose in insert paper. The average dosage of amikacin was $11\pm2.1$ mg/kg every 12 hours (In case of tobramycin, $2.09\pm0.37$ mg/kg every 8 hours or $2.59\pm0.20$ mg/kg every 12 hours). The relationship between AGs volume of distribution and sex, serum albumin (g/dl), body mass index $(kg/m^2)$, body weight change $(\%)$, the amount of fluid inpu (ml/kg/day), the degree of hematocrit decrease $(\%)$ were studied respectively. Univariate anlysis revealed that body mass index $(kg/m^2)$, the amount of fluid input (ml/kg/day) and the degree of hematocrit decrease $(\%)$ had significant correlation with aminoglycosides volume of distribution. But sex, serum albumin, body weight change $(\%)$ had no significant correlation with aminoglycosides volume of distribution.

• 한국도로학회논문집
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• 제16권1호
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• pp.57-62
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• 2014

PURPOSES : Capacity is a main factor of determining the number of lane in highway design or the level of service in road on operation. Previous studies showed that breakdown may occur before capacity is reached, and then it was concluded that capacity is a stochastic value rather than a deterministic one. In general, estimating capacity is based on average over maximum traffic volume observed for capacity state. This method includes the empirical distribution method(EDM) and would underestimate capacity. This study estimated existing empirical methods of estimating stochastic highway capacity. Among the studied methods are the product limit method(PLM) and the selected method(SM). METHODS : Speed and volume data were collected at three freeway bottleneck sites in Cheonan-Nonsan and West Sea Freeway. The data were grouped into a free-flow state or capacity state with speeds observed in the bottlenecks and the upstream. The data were applied to the empirical methods. RESULTS : The results show that the PLM and SM estimated capacity higher than EDM. The reason is that while the EDM is based on capacity observations only, the PLM and SM are based on free-flow high volumes and capacity observations. CONCLUSIONS : The PLM and SM using both free-flow and capacity observations would be improved to enhance the reliability of the capacity estimation.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2008년도 춘계 학술발표회 제20권1호
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• pp.745-748
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• 2008

On investigation about quick measurement technology of unit water at range of W/B=35% in high strength, the average error of the Di-electric constant moisture tester A has measured more than $23.0kg/m^3$ unit water content of design and the average error of the method of unit volume weigh was less than $-9.6kg/m^3$. The average error with mixing factor has influenced with a kind of sand, but had not influenced with unit water content of design. Therefore, it will be for introduce business decide require more than a study about cement, sand, superplasticizer, etc.