Korean Journal of Clinical Pharmacy (한국임상약학회지)
- Volume 12 Issue 1
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- Pages.7-12
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- 2002
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- 1226-6051(pISSN)
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- 2508-786X(eISSN)
Aminoglycoside Dosage in Neutropenic Fever Patients after Tranplantation of Blood Stem Cells
조혈모 세포 이식후 neutropenic fever환자에서의 aminoglycoside dosage에 관한 검토
- Choi, M Y (Dept. of Pharmacy Seoul National University Hospital) ;
- Kim, M J (Dept. of Pharmacy Seoul National University Hospital) ;
- Kim, H S (College of Pharmacy, Chungnam National University) ;
-
Shin, W G
(College of Pharmacy, Seoul National University) ;
- Kim, G S (Dept. of Pharmacy, Seoul National University Hospital) ;
- Sohn, I J (Dept. of Pharmacy, Seoul National University Hospital)
- 최미영 (서울대학교병원 약제부) ;
- 김민정 (서울대학교병원 약제부) ;
- 김호순 (충남대학교 약학대학) ;
-
신완균
(서울대학교 약학대학) ;
- 김귀숙 (서울대학교병원 약제부) ;
- 손인자 (서울대학교병원 약제부)
- Published : 2002.03.01
Abstract
Pharmacokinetic parameters and dosage of aminoglycosides (AGs) were studied retrospectively in 36 patients with neutropenic fever after stem cell transplantation in Seoul National University Hospital from July 1996 to June 2001. AGs pharmacokinetic parameters were calculated with steady-state peak and trough serum drug concentrations by the method of Sawchuk and Zaske et at. The calculated aminoglycosides volume of distribution and clearance were greater than population value
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