• 제목/요약/키워드: Association study

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거주지관리제도 도입을 위한 미국 주택소유자조합의 기능과 관리방식에 관한 연구 (A Study on the function and Management Models of American Homeowners Association for Introducing Residential Area Management System in Korea)

  • 박경옥
    • 한국생활과학회지
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    • 제15권4호
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    • pp.691-701
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    • 2006
  • The purpose of this study is to find out a way to apply the strength of American homeowners association to Korean housing management system through literature review on the legal basis, organizational composition and functions, and management models of homeowners association. Following is distinctive characteristics of American homeowners association. 1) Homeowners association is a juridical entity which 'Condominium Act' obliges residents to join. 2) The board of directors is decision maker. The covenant, however, gives residents right to act in committees. 3) Homeowners association has self-governing functions such as management of common spaces, permission of new construction and taxation. 4) Types of management are volunteers' self-management, association-employed management, full agency management, and some mixed types. Residents pay management charge by month or by quarter. This study suggests as follow. 1) It is needed for Korea to legislate the law to regulate the management system of detached houses. 2)Management system of Korea can be more efficient with volunteers' committees for active participation. Above all, architectural control committee is essential in the circumstance that reform of apartment is popular these days. 3) The management entity is recommended to have some self-governing function to talk about taxation policy with local governments.

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새가족법에 따른 이혼판례에 대한 고찰 (Study of Divorce Cases under New Family Law in Korea)

  • 신순자
    • 대한가정학회지
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    • 제34권2호
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    • pp.355-365
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    • 1996
  • This is a study of divorce cases under new family law in Korea specifically during the period of May 1991 to November 1995. This study comprises 33 cases that appeared on two daily newspapers, Chosun-ilbo and Kookmin-ilbo during that period. This study contains the analysis on the rights of Korean women at the time of divorce.

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KARE Genomewide Association Study of Blood Pressure Using Imputed SNPs

  • Hong, Kyung-Won;Lim, Ji-Eun;Kim, Young-Jin;Cho, Nam-H.;Shin, Chol;Oh, Berm-Seok
    • Genomics & Informatics
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    • 제8권3호
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    • pp.103-107
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    • 2010
  • The imputation of untyped SNPs enables researchers to validate association findings across SNP arrays and also enables them to test a large number of SNPs to reveal the fine structure of the association peak, facilitating interpretation of the results and the location of causal polymorphisms. In this study, we applied the imputation method to a genomewide association study and recapitulated the previously associated gene loci of blood pressure traits in Korean cohorts. A total of 1,827,004 SNPs were imputed by the IMPUTE program, and we conducted a genomewide association study for systolic and diastolic blood pressure. While no SNPs passed the Bonferroni correction p-value (p=$2.74{\times}10^{-8}$ for 1,827,004 SNPs), 12 novel loci for systolic blood pressure and 16 novel loci for diastolic blood pressure were detected by imputed SNPs, with $10^{-5}$ < p-value < $10^{-4}$. Moreover, 7 regions (ATP2B1, 10p15.1, ARHGEF12, ALX4, LIPC, 7q31.1, and TCF7L2) out of 14 genetic loci that were previously reported revealed that the imputed SNPs had lower p-values than those of genotyped SNPs. Moreover, a nonsynonymous SNP in the CSMD1 gene, one of the 14 genes, was found to be associated with systolic blood pressure (p<0.05). These results suggest that the imputation method can facilitate the discovery of novel SNPs as well as enhance the fine structure of the association peak in the loci.

Effect of Design Elements and Brand Identity on Brand Association, Brand Personality, and Brand Image: Focusing on Franchisee Coffee Shop

  • SHON, Jung Hieh;SONG, Jisung
    • 한국프랜차이즈경영연구
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    • 제12권3호
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    • pp.21-34
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    • 2021
  • Purpose: As the visual expression cue that can easily reveal and imprint the brand image to consumers becomes more important, franchise coffee shops are making various efforts to establish design elements and brand identity. Therefore, the purpose of this study is to examine the structural model between design elements, brand identity, brand association, brand personality, and brand image of franchise coffee shops from various angles, and to suggest a plan for using visual elements makes a brand image on the franchise in the future. Research design, data, and methodology: This study tests the structural relationship between design elements, brand identity, brand association, brand personality, and brand image of franchise coffee shops. design elements are divided into three attributes (interior design, product design). And brand identity is divided into two attributes (brand name, brand symbol/logo). In order to achieve the purposes of this research, research model and hypotheses were developed based on previous researches. All constructs were measured with multiple items developed and tested in the previous studies. The data were collected from 380 customers who visited franchise coffee shops and were analyzed through SPSS 26.0 and SmartPLS 3.0 statistical package program. Result: As a result of this study, first, it is confirmed that product design has a positive effect on brand association toward coffee shops. Second, interior design and product design have a positive effect on brand personality. Third, all brand identity have a significant positive impact on brand association and brand personality. Finally, brand association and brand personality of coffee specialty shops have a positive effect on brand image. Conclusions: The following implications of this study are as follows. This study is confirmed that there is an effect of design elements attributes and brand identity attributes on brand association and brand personality. And, the brand image was found to be influenced by brand association and brand personality. This suggests that it can be used to establish visible marketing strategies for franchise coffee shops. Therefore, it is necessary to further improve efforts to raise the level of the brand image through visual factors such as unusual interior design, product packages.

한국가족자원경영학회지에 게재된 연구의 경향 및 발전방향 (A Review of the Studies Published in Journal of Korean Family Resource Management Association: The Trends and Beyond)

  • 이연숙;한지수;한영선;김하늬
    • 가족자원경영과 정책
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    • 제13권3호
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    • pp.207-226
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    • 2009
  • The purposes of this study are to evaluate the research trends of articles published in the Journal of the Korean Family Resource Management Association from 1997 to 2008, and to identify the contributions as well as the inherent limitations of these articles in the field of family resource management. For these purposes, this study analyzed 3 types of research trends: research topic, research method including data analysis, and research subject. The findings of this study are as follows. First of all, the study shows that most number of researches are conducted on management subjects, followed by management practice and management theory. Secondly, regarding the frequency of the research method, the empirical researches are the most prevalent method employed by the researches, over literature or practice researches. Thirdly, it is noted there are more quantitative researches than qualitative ones. Finally, there are a lot more researches carried out on the traditional household than those of vulnerable households.

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Genome-association analysis of Korean Holstein milk traits using genomic estimated breeding value

  • Shin, Donghyun;Lee, Chul;Park, Kyoung-Do;Kim, Heebal;Cho, Kwang-hyeon
    • Asian-Australasian Journal of Animal Sciences
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    • 제30권3호
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    • pp.309-319
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    • 2017
  • Objective: Holsteins are known as the world's highest-milk producing dairy cattle. The purpose of this study was to identify genetic regions strongly associated with milk traits (milk production, fat, and protein) using Korean Holstein data. Methods: This study was performed using single nucleotide polymorphism (SNP) chip data (Illumina BovineSNP50 Beadchip) of 911 Korean Holstein individuals. We inferred each genomic estimated breeding values based on best linear unbiased prediction (BLUP) and ridge regression using BLUPF90 and R. We then performed a genome-wide association study and identified genetic regions related to milk traits. Results: We identified 9, 6, and 17 significant genetic regions related to milk production, fat and protein, respectively. These genes are newly reported in the genetic association with milk traits of Holstein. Conclusion: This study complements a recent Holstein genome-wide association studies that identified other SNPs and genes as the most significant variants. These results will help to expand the knowledge of the polygenic nature of milk production in Holsteins.

Association Analysis between Genes' Variants for Regulating Mitochondrial Dynamics and Fasting Blood Glucose Level

  • Jung, Dongju;Jin, Hyun-Seok
    • 대한의생명과학회지
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    • 제22권3호
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    • pp.107-114
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    • 2016
  • Maintenance of fasting blood glucose levels is important for glucose homeostasis. Disruption of feedback mechanisms are a major reason for elevations of glucose level in blood, which is a risk factor for type 2 diabetes mellitus that is mainly caused by malfunction of pancreatic beta-cell and insulin. The fasting blood glucose level has been known to be influenced by genetic and environmental factors. Mitochondria have many functions for cell survival and death: glucose metabolism, fatty acid oxidation, ATP generation, reactive oxygen species (ROS) metabolism, calcium handling, and apoptosis regulation. In addition to these functions, mitochondria change their morphology dynamically in response to multiple signals resulting in fusion and fission. In this study, we aimed to examine association between fasting blood glucose levels and variants of the genes that are reported to have functions in mitochondrial dynamics, fusion and fission, using a cohort study. A total 416 SNPs from 36 mitochondrial dynamics genes were selected to analyze the quantitative association with fasting glucose level. Among the 416 SNPs, 4 SNPs of PRKACB, 13 SNPs of PPP3CA, 6 SNPs of PARK2, and 3 SNPs of GDAP1 were significantly associated. In this study, we were able to confirm an association of mitochondrial dynamics genes with glucose levels. To our knowledge our study is the first to identify specific SNPs related to fasting blood glucose level.

초등학교 여학생의 환경과 유전적 요인 및 비만도와 성적성숙도와의 관련성에 대한 연구 (Relationship of Environmental Factors, Genetic Factors and Obesity with Sexual Maturity among Elementary School Girls)

  • 박준희;김영옥
    • 대한영양사협회학술지
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    • 제12권3호
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    • pp.225-234
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    • 2006
  • The purpose of this study was to identify the factors that related to obesity among 6th grade elementary school girls. The study subjects were 337 girls residing in Seoul. Not only variables of nutritional environment such as eating habits, health related behavioral variables, nutritional feeding methods during infancy, and genetic factors but also sexual maturity had been included as a obesity related factors. Association between obesity and related variables were analyzed by $x^2$(Chi-square) test. The obesity prevalence of the study subjects were 16% based on Röhrer Index(RI). Fifty-three percent of the study subjects experienced menarche at the time of data collection. Result of analysis showed that not only the nutritional enviromental variables such as eating habits, specific food preferences, and habit of exercise but also genetic factors did not show any statistically significant association with obesity. Above finding may imply that more variables other than the variables included in this study might have influenced on the obesity of the children. However sexual maturity in term of breast development showed significant association with obesity.

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열량 및 열량영양소 섭취량과 관련된 유전자 변이에 대한 전장유전체 연관성 분석연구 (Genetic Variants Associated with Calorie and Macronutrient Intake in a Genome-Wide Association Study)

  • 백인경;안윤진;이승구;김소리울;한복기;신철
    • Journal of Nutrition and Health
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    • 제43권4호
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    • pp.357-366
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    • 2010
  • There has been no genome-wide association study (GWAS) for macronutrient intake as a quantitative trait. To explore genetic loci associated with total calorie and macronutrient intake, genome-wide association data of autosomal single nucleotide polymorphisms (SNPs) from Korean adults were analyzed. We conducted a GWAS in 3,690 men and women aged 40 to 60 years from an urban population-based cohort. At the baseline examination (June 18, 2001 through January 29, 2003), DNA samples of the study subjects were collected and analyzed for genotyping. The information of average daily consumption of total calorie, carbohydrate, protein, and fat was obtained from a semi-quantitative food frequency questionnaire and transformed by natural logarithm for analyses after adjustment of calorie intake. Using multivariate linear regression analysis adjusted for age, sex, and height, we tested for 352,021 SNPs and found weak associations, which do not reach genome-wide association significance, with calorie and macronutrient intake. However, a number of SNPs were found to have potential associations with macronutrient intake; in particular, signals in SORBS1 and those in PRKCB1 were likely associated with carbohydrate and fat intake, respectively. We observed an inverse association between the minor allele of the SNPs in these genes and the amount of consumption of carbohydrate or fat. Our GWAS identified loci and minor alleles weakly associated with macronutrient intake. Because SORBS1 and PRKCB1 are reportedly associated with the metabolism of glucose and lipid as well as with obesity-related diseases, further investigations on biological and functional roles of polymorphism of these genes in the relation to macronutrient intake are warranted.