A statistical approach is employed to investigate the relative advantages of several alternative fuel cycles suitable for a hypothetical 1125 MWe plant in Korea. All the fuel cost parameters are treated as statistical variables, each being associated with an appropriate probability distribution function. Through a random sampling procedure, the probability histograms on both capital requirements and break-even costs of various fuel cycle components are obtained. The histograms are then utilized to quantify the cost-benefit of the fuel cycle with reprocessing or the plutonium recycle over the throwaway cycle.
Fine particulate matter (FPM; diameter ≤ 2.5 ㎛) is frequently found in metropolitan areas due to activities associated with rapid urbanization and population growth. Many adolescents spend a substantial amount of time at school where, for various reasons, FPM generated outdoors may flow into indoor areas. The aims of this study were to estimate FPM concentrations and categorize types of FPM in schools. Meteorological and chemical variables as well as satellite-based aerosol optical depth were analyzed as input data in a random forest model, which applied 10-fold cross validation and a grid-search method, to estimate school FPM concentrations, with four statistical indicators used to evaluate accuracy. Loose and strict standards were established to categorize types of FPM in schools. Under the former classification scheme, FPM in most schools was classified as type 2 or 3, whereas under strict standards, school FPM was mostly classified as type 3 or 4.
Heera Yoen;Soo-Yeon Kim;Dae-Won Lee;Han-Byoel Lee;Nariya Cho
Korean Journal of Radiology
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v.24
no.7
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pp.626-639
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2023
Objective: To investigate the association of clinical, pathologic, and magnetic resonance imaging (MRI) variables with progressive disease (PD) during neoadjuvant chemotherapy (NAC) and distant metastasis-free survival (DMFS) in patients with triple-negative breast cancer (TNBC). Materials and Methods: This single-center retrospective study included 252 women with TNBC who underwent NAC between 2010 and 2019. Clinical, pathologic, and treatment data were collected. Two radiologists analyzed the pre-NAC MRI. After random allocation to the development and validation sets in a 2:1 ratio, we developed models to predict PD and DMFS using logistic regression and Cox proportional hazard regression, respectively, and validated them. Results: Among the 252 patients (age, 48.3 ± 10.7 years; 168 in the development set; 84 in the validation set), PD was occurred in 17 patients and 9 patients in the development and validation sets, respectively. In the clinical-pathologic-MRI model, the metaplastic histology (odds ratio [OR], 8.0; P = 0.032), Ki-67 index (OR, 1.02; P = 0.044), and subcutaneous edema (OR, 30.6; P = 0.004) were independently associated with PD in the development set. The clinical-pathologic-MRI model showed a higher area under the receiver-operating characteristic curve (AUC) than the clinical-pathologic model (AUC: 0.69 vs. 0.54; P = 0.017) for predicting PD in the validation set. Distant metastases occurred in 49 patients and 18 patients in the development and validation sets, respectively. Residual disease in both the breast and lymph nodes (hazard ratio [HR], 6.0; P = 0.005) and the presence of lymphovascular invasion (HR, 3.3; P < 0.001) were independently associated with DMFS. The model consisting of these pathologic variables showed a Harrell's C-index of 0.86 in the validation set. Conclusion: The clinical-pathologic-MRI model, which considered subcutaneous edema observed using MRI, performed better than the clinical-pathologic model for predicting PD. However, MRI did not independently contribute to the prediction of DMFS.
Ko, Chanyoung;Kim, Jae-Jin;Cho, Dongrae;Oh, Jooyoung;Park, Jin Young
Korean Journal of Psychosomatic Medicine
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v.27
no.2
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pp.101-110
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2019
Objectives : It is not clear which clinical variables are most closely associated with delirium in the Intensive Care Unit (ICU). By comparing clinical data of ICU delirium and non-delirium patients, we sought to identify variables that most effectively differentiate delirium from non-delirium. Methods : Medical records of 6,386 ICU patients were reviewed. Random Subset Feature Selection and Principal Component Analysis were utilized to select a set of clinical variables with the highest discriminatory capacity. Statistical analyses were employed to determine the separation capacity of two models-one using just the selected few clinical variables and the other using all clinical variables associated with delirium. Results : There was a significant difference between delirium and non-delirium individuals across 32 clinical variables. Richmond Agitation Sedation Scale (RASS), urinary catheterization, vascular catheterization, Hamilton Anxiety Rating Scale (HAM-A), Blood urea nitrogen, and Acute Physiology and Chronic Health Examination II most effectively differentiated delirium from non-delirium. Multivariable logistic regression analysis showed that, with the exception of vascular catheterization, these clinical variables were independent risk factors associated with delirium. Separation capacity of the logistic regression model using just 6 clinical variables was measured with Receiver Operating Characteristic curve, with Area Under the Curve (AUC) of 0.818. Same analyses were performed using all 32 clinical variables;the AUC was 0.881, denoting a very high separation capacity. Conclusions : The six aforementioned variables most effectively separate delirium from non-delirium. This highlights the importance of close monitoring of patients who received invasive medical procedures and were rated with very low RASS and HAM-A scores.
The Statistical regression model has been used to construct crash prediction models, despite its limitations in assuming data distribution and functional form. In response to the limitations associated with the statistical regression models, a few studies based on non-parametric methods such as neural networks have been proposed to develop crash prediction models. However, these models have a major limitation in that they work as black boxes, and therefore cannot be directly used to identify the relationships between crash frequency and crash factors. A genetic programming model can find a solution to a problem without any specified assumptions and remove the black box effect. Hence, this paper investigates the application of the genetic programming technique to develope the crash prediction model. The data collected from the Gyeongbu expressway during the past three years (2010-2012), were separated into straight and curve sections. The random forest technique was applied to select the important variables that affect crash occurrence. The genetic programming model was developed based on the variables that were selected by the random forest. To test the goodness of fit of the genetic programming model, the RMSE of each model was compared to that of the negative binomial regression model. The test results indicate that the goodness of fit of the genetic programming models is superior to that of the negative binomial models.
Background: The purpose of this study was to analyze the medical expense change and influencing factors after introducing longterm care insurance system. The study period was 2 years before and after introduction of the system. Methods: We analyzed data collected from two divided group lived in Incheon. Four hundred and eighty-five elderly who received long-term care wage for one year were selected for experimental group. For control group, 1,940 elderly were selected by gender and age stratified random sampling. Difference-In-difference analyses was used for evaluating policy effectiveness. Also multiple regression analyses were conducted to identify the factors associated with total medical expenditures. The control variables were demographic variables, economic status, diseases, and medical examination variables. Results: Difference-in-difference analyses showed that total average medical expenses among long-term patients has decreased by 61.85%. Of these, the hospitalization expenses have decreased by 91.63% and the drug expenses have increased by 31.85%. Multiple regression analyses results showed that total average medical expenses among long-term patients have significantly decreased by 46.5% after introducing the long-term care insurance. The hospitalization expenses have significantly decreased by 148.5%, whereas the drug expenses have increased by 53.6%. And outpatient expenses have increased by 10.4%, but the differences were not statistically significant. Conclusion: The results showed that total medical expenses and hospitalization expenses have decreased after introducing the long-term care insurance. These results could support the opinion that the health insurance spending among long-term patients will be reduced gradually by long-term care insurance through changing medical demand.
The objectives of this study were as follows: 1) To describe the group of selected disabled homemakers in terms of demographic and medical variables related to organizational activities in the home and family participation in household activities. 2) To identify those demograhpic and medical variables that were related to organizational activities in the home and family participation in household activities. 3) To identify relationship between organizational activities in the home and family participation in household activities. Questionnaires were given to the selected disabled homemakers living in Seoul. The sample was small(N=35) and it was not random; therefore generalizations could not be made to the population as a whole. Data were analyzed by mean, Kruskal-Wallis one-way analysis of variance by ranks, and Spearman rank correlation coefficients. Homemaker's organizational activities were measured by 16 items about physical and mental activities from Mumaw's Organizational Activities Index. Family participation in household activities was measured by 8 items about how often family members participated in two areas of household activities: house chores and extra-activities. The results were as follows: 1) The homemaker's higher organizational activities scores were associated with younger homemaker, higher the level of education, small households, and higher the economic status. The homemaker without children performed better organizational household activities. The homemaker with shorter the duration of disability performed better organizational activities. The homemaker who needed crutches for mobility performed better organizational household activities. 2) The homemaker who was younger, higher the level of education, with smaller households, and lower the economic level was helped by husband. Husband helped better the homemaker with shorter the duration of disability in household activities. 3) Factors affecting children's participation in disabled homemaker's house chores and extra-activities were the age of homemaker and the marital status. The homemaker was single and older, the children were more helpful. 4) Task standardization score was the highest among the factors of homemaker's organizational activities and families with a disabled homemaker participated more extensively than families with abled homemaker. 5) Significant intercorrelation was found between the dependent variables.
Objective: Previous epidemiologic studies demonstrated that obesity might associated with the risk of bladder cancer. However, many of the actual association findings remained conflicting. To better clarify and provide a comprehensive summary of the correlation between obesity and bladder cancer risk, we conducted a meta-analysis to summarize results of studies on the issue. Stratified analyses were also performed on potential variables and characteristics. Methods: Studies were identified by searching in PubMed and Wanfang databases, covering all the papers published from their inception to March 10, 2013. Summary relative risks (SRRs) with their corresponding 95% confidence intervals (CIs) were calculated by either random-effect or fixed-effect models. Results: A total of 11 cohort studies were included in our meta-analysis, which showed that obesity was associated with an increased risk for bladder cancer in all subjects (RR=1.10, 95% CI=1.06-1.16; p=0.215 for heterogeneity; $I^2$=24.0%). Among the 9 studies that controlled for cigarette smoking, the pooled RR was 1.09 (95% CI 1.01-1.17; p=0.131 for heterogeneity; $I^2$=35.9%). No significant publication bias was detected (p = 0.244 for Egger's regression asymmetry test). Conclusions: Our results support the conclusion that obesity is associated with the increased risk of bladder cancer. Further research is needed to generate a better understanding of the correlation and to provide more convincing evidence for clinical intervention in the prevention of bladder cancer.
Objectives: The Chepang people, an indigenous ethnic group in Nepal, experience substantial marginalization and socioeconomic disadvantages, making their communities among the most vulnerable in the region. This study aimed to determine the prevalence and factors associated with adolescent pregnancy in the Chepang communities of Raksirang Rural Municipality, Makwanpur District, Bagmati Province, Nepal. Methods: A cross-sectional study was conducted from October 2022 to April 2023 among 231 Chepang women selected using simple random sampling from Raksirang Rural Municipality. A semi-structured questionnaire was used for interviewing the mothers. Bivariate and multivariate logistic regression analyses were performed, using odds ratios with 95% confidence intervals (CIs). Variables with a variation inflation factor of more than 2 and a p-value of more than 0.25 were excluded from the final model. Results: The study revealed that the prevalence rate of adolescent pregnancy among Chepang women was 71.4% (95% CI, 65.14 to 77.16). A large percentage of participants (72.7%) were married before the age of 18 years. Poor knowledge of adolescent pregnancy (adjusted odds ratio [aOR], 10.3; 95% CI, 8.42 to 14.87), unplanned pregnancy (aOR, 13.3; 95% CI, 10.76 to 19.2), and lack of sex education (aOR, 6.57; 95% CI, 3.85 to 11.27) were significantly associated with adolescent pregnancy. Conclusions: The prevalence of adolescent pregnancy among the Chepang community was high. These findings highlighted the importance of raising awareness about the potential consequences of adolescent pregnancy and implementing comprehensive sexuality education programs for preventing adolescent pregnancies within this community.
AL-ABSY, Mujeeb Saif Mohsen;ALMAAMARI, Qais;ALKADASH, Tamer;HABTOOR, Ammar
The Journal of Asian Finance, Economics and Business
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v.7
no.12
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pp.181-193
/
2020
This study examines the relationship between gender diversity (women on the board and women on the audit committee) and a firm's financial stability. The ordinary least square analysis was used to determine the relationship. To measure the financial stability of Malaysian suspect firms, i.e., firms with the lowest positive earnings, the Altman (1993) Z-Score measurement was utilized. The results indicate that women on the board are significantly and negatively associated with the firm's financial stability. That is, they are related to low financial stability, which contradicts the agency and resource dependence theories. Regarding women directors on the audit committee, there is no significant relationship with financial stability, meaning that they cannot protect the company against financial distress. These results are robust and do not change when using different measurements of gender diversity, one-year lag of independent variables, and other methods of analysis, namely random effect panel data. This study is the first to alert policymakers, stakeholders, researchers, and society in general to the need to re-evaluate and strengthen the role of women directors in improving firms' financial stability, particularly in emerging economies like Malaysia.
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