• The Korean Journal of Applied Statistics
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• v.28 no.4
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• pp.663-683
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• 2015

The change of the population pyramid due to low fertility and rapid aging threatens the financial sustainability of National Health Insurance. We construct statistical models for prevalence rates and medical expenses using National Health Insurance Service (NHIS) sample cohort data from 2002-2013. We then project yearly expenditures and income of national health insurance until 2060 that considers various assumptions in regards to future population structure and economic conditions. We adopt a VECM-LC model for prevalence rates and the double exponentially smoothing method for the per capita co-payment of healthcare expense (in which the two models are institution-disease-sex-age specific) to project of national health insurance expenditures. We accommodate various assumptions of economic situations provided by the national assembly and government to produce a financial projection for national health insurance. Two assumptions of dependents ratios are used for the projection of national health insurance income to conduct two future population structures by the two assumptions of aging progresses and various assumptions on economic circumstances as in the expenditure projection. The health care deficit is projected to be 20-30 trillion won by 2030 and 40-70 trillion won by 2060 in 2015 constant price.

• Journal of the Korean Electrochemical Society
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• v.4 no.4
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• pp.172-175
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• 2001

Nanophase catalyst layer for direct methanol fuel cell has been fabricated by magnetron sputtering method. Catalyst metal targets and carbon were sputtered simultaneously on the Nafion membrane surface at abnormally higher gas (Ar/He mixture) pressure than that of normal thin film processing. They could be coated as a novel structure of catalyst layer containing porous PtRu or Pt and carbon particles both in nanometer range. Membrane electrode assembly made with this layer led to a reduction of the catalyst loading. At the catalyst loading of 1.5mg $PtRu/cm^2$ for anode and 1mg $Pt/cm^2$ for cathode, it could provide $45 mW/cm^2$ in the operation at 2 M methanol, 1 Bar Air at 80"C. It is more than $30\%$ increase of the power density performance at the same level of catalyst loading by conventional method. This was realized due to the ultra fine particle sizes and a large fraction of the atoms lie on the grain boundaries of nanophase catalyst layer and they played an important role of fast catalyst reaction kinetics and more efficient fuel path. Commercialization of direct methanol fuel cell for portable electronic devices is anticipated by the further development of such design.

• Journal of Digital Convergence
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• v.13 no.4
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• pp.303-310
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• 2015

Game technologies are now applied in various engineering areas such as the simulation of surgical operation or the implementation of a cyber model house. One of the essential and important technology in these applications is cutting of the 3D polygon model in real time. Real-time cutting technology is an essential technology needed to implement the simulation of a building demolition or a car assembly for training or educational purpose. Previous cutting method using the conventional BSP-Tree structure has some limitations in that they divide the whole world including the 3D model and its environment, only into two parts with respect to an infinite plane. In this paper, we show a technique cutting the 3D model in a finite extent in order to solve this problem. Specifically, we restricted the cut surface in a finite rectangular area and constructed the mesh for the divided surface. To show the usefulness of our partial cutting technique, an example of the dismantling process simulation of a nuclear reactor polygon model was illustrated.

• The Korean Journal of Mycology
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• v.41 no.1
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• pp.1-8
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• 2013

COP9 signalosome (CSN), which is originally identified as the regulator of the photomorphogenic development in plant, is highly conserved protein complex in diverse eukaryotic organisms. Most eukaryotic CSN complex is composed of 8 subunits, which is structurally and functionally similar to the lid subunit of 26S proteasome and eIF3 translation initiation complex. CSN play important functions in the regulation of cell cycle and checkpoint response by controlling Cullin-Ring E3 ubiquitin ligases (CRL) activities. CSN exhibits an isopeptidase activity which cleaves the neddylated moiety of cullin components. In fission yeast, S-phase cell cycle progression was delayed and the sensitivity to g-ray or UV was increased in CSN1 and CSN2 deletion mutants, indicating that yeast CSN is also involved in the checkpoint regulation. CSN in fungal system more closely resembles that of the higher organisms in the structure and assembly of their components. Functionally, CSN is associated with the regulation of conidiation rhythms in Neurospora crassa and the sexual development in Aspsergillus nidulans. Recent studies also revealed that CSN functions as an essential cell cycle regulator, playing key roles in the regulation of DNA replication and DNA damage response in Aspergillus. Overall, CSN of microorganisms, such as fission yeast and fungi, share functionally common aspects with higher organisms, implying that they can be useful tools to study the role of CSN in the CRL-mediated diverse cellular activities.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.2
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• pp.189-197
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• 2018

Objective: Hemicastration is a unilateral orchiectomy to remove an injured testis, which can induce hormonal changes and compensatory hypertrophy of the remaining testis, and may influence spermatogenesis. However, the underlying molecular mechanisms are poorly understood. Here, we investigated the impact of hemicastration on remaining testicular function. Methods: Prepubertal mice (age 24 days) were hemicastrated, and their growth was monitored until they reached physical maturity (age 72 days). Subsequently, we determined testis DNA methylation patterns using reduced representation bisulfite sequencing of normal and hemicastrated mice. Moreover, we profiled the testicular gene expression patterns by RNA sequencing (RNA-seq) to examine whether methylation changes affected gene expression in hemicastrated mice. Results: Hemicastration did not significantly affect growth or testosterone (p>0.05) compared with control. The genome-wide DNA methylation pattern of remaining testis suggested that substantial genes harbored differentially methylated regions (1,139) in gene bodies, which were enriched in process of protein binding and cell adhesion. Moreover, RNA-seq results indicated that 46 differentially expressed genes (DEGs) involved in meiotic cell cycle, synaptonemal complex assembly and spermatogenesis were upregulated in the hemicastration group, while 197 DEGs were downregulated, which were related to arachidonic acid metabolism. Integrative analysis revealed that proteasome 26S subunit ATPase 3 interacting protein gene, which encodes a protein crucial for homologous recombination in spermatocytes, exhibited promoter hypomethylation and higher expression level in hemicastrated mice. Conclusion: Global profiling of DNA methylation and gene expression demonstrated that hemicastration-induced compensatory response maintained normal growth and testicular morphological structure in mice.

• Cartoon and Animation Studies
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• s.47
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• pp.381-412
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• 2017

Character conveys rich storytelling and various design elements. Domestic characters are changing and developing in various forms through SNS and offline sources, which are being developed in the aspect of contents industry. The purpose of this study is to find out and discuss the factors that character users are using Korean characters as storytelling and color factor. In terms of storytelling, they prefer adventure, fantasy, absurd and humorous stories. In terms of color, it seems that they prefer a character with simple and simple color/ warm color and warm / cute color composition. On the other hand, characters with a simple story, which is the main subject of early childhood education, fashion, or toys in the aspect of storytelling, are not preferred. In terms of color, it was shown that 4 or more colors were combined without a main color. These main colorless characters gave complex feelings that are not preferred. In terms of storytelling, it is necessary to develop and develop the contents of OSMU(One-source Multi use) through story development with adventure and fantasy structure. In terms of color, it is necessary to configure the user with a simple and simple color which is preferred by the users. Also, the assembly robot toy character needs to increase the satisfaction of the character through simple color composition. As a result of this study, the factors that satisfy the users in terms of storytelling and color are derived. These results will contribute to the development of theoretical aspects, storytelling aspects, and character design industry aspects. Despite the significance of the above paper, it was inevitable to limit the research on the analysis of the storytelling of specific characters, the research through the color analysis framework, the accurate data analysis on the color analysis, and the simple comparative analysis of one.

• Journal of Korea Water Resources Association
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• v.43 no.10
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• pp.893-909
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• 2010

The purpose of this study is to consider the interaction between surface water and groundwater in basin scale by developing TANK_GS model. The soil moisture structure of tank model with 3 tanks is improved to simulate the appropriate stream-aquifer interactions. Maximum likelihood method is applied to calibrate parameters with variance functions to deal with heteroscedasticity of residuals. The parameters of improved TANK_GS model and variance function are simultaneously estimated by Simulated Annealing method, a global optimization technique. The results of TANK-GE are compared to those of the SWMM-GE model which had been developed to consider the stream-aquifer interactions. The new TANK_GS model and SWMM-GE model are applied to Gapcheon basin, which belongs to Geum River basin. TANK_GS model showed better model performance compared to the original TANK model and characterized the relationship of stream-aquifer interactions as satisfactorily as the SWMM-GE model. The sustainable groundwater yield can be estimated for the regional water resources planning using the TANK_GS model

• Korean journal of communication and information
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• v.45
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• pp.187-219
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• 2009

Under the pressure of the selection of topics and the presentation rules of mass media, politics in media society increasingly resort to professionalized forms of theatrical staging as a means of self-portrayal. Although these staging methods are not contradictory to what is actually going on in politics, they strongly advantage the tendency to focus exclusively on the staging of an event. Through their competition for public attention, politicians have been developing sophistication regarding placement and staging of events as well as regarding factual information. In the process of this transformation, politics that are issue-related and based on binding decisions are being gradually transformed into symbolic politics. Moreover, through their appearance on TV, politicians first of all need to possess presentational skills which are not necessarily related to their political achievements. Still, presentational skills decide over the success in politics of those politicians. The reason is that a politician who possesses presentational skills is still being perceived as being successful even if his political achievements notedly lag behind. On the other hand, political achievements are being underrated if a politician lacks the talent to present himself in front of the media. “The staging of politics, “politainment”, on the stage of mass media is evolving into a key structure which is responsible for a new coinage of politics in all different kinds of dimensions: the selection of staff, the role of action programs and their impact for the legitimation of political acting, even in relation to therole of pivotal political institutions such as parties and parliaments in the political process. The TV debates during the Bundestag elections of the year 2002 and 2005 are being analyzed and judged as “staging of politics”(politainment). Self-dramatization in media society concerning media discourses about politics and political self-portrayal has become a basic principle of political communication. Self-dramatization is a vital challenge for adequate political communication and content-based orientation in our present media democracies.

• Korean journal of communication and information
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• v.51
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• pp.5-25
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• 2010

The purpose of this research examined the relationship between the level of news usage on Influenza A(H1N1) and media users' behavioral intention toward health protection. Specifically, the study investigated causal relationships among exposure of media information on Influenza A(H1N1) as an independent variable, psychological protection motivation factors such as perceived severity, vulnerability, response efficacy, & self-efficacy as mediated variables and behavioral intention on personal and public health protection as dependent variables using structure equation model analysis. Self-reported questionnaires were administrated to 460 college students. The result indicated the followings. First, the level of news usage on Influenza A(H1N1) was not statistically significant on influencing behavioral intention toward personal and public health protection. Second, perceived severity, vulnerability, and self-efficacy were significant variables on behavioral intention toward personal health protection whereas perceived vulnerability and response efficacy were significant on public health protection. The function among factors in protection motivation theory is dependent upon whom protected from illness.

• Applied Chemistry for Engineering
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• v.29 no.2
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• pp.162-167
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• 2018

The effect of the average particle size and shape of silver nanoparticles for the transparent conductive film (TCF) was studied. Optical and electrical properties of silver conductive lines coated on the polyethylene terephthalate (PET) film was also measured. Silver nanoparticles produced by Ag-CM, Ag-ME, Ag-EE methods showed an excellent conductivity compared to those produced by Ag-EB, Ag-CR and Ag-PL methods, but a little difference in the transparency. In the case of the former three silver nanoparticles, the average particle size was about 80 nm or less and the size was uniform. For the latter case, the severe agglomeration phenomena of particles was observed and the average particle size was 100 nm or more. This result was consistent with the result of the uniformity of the pattern shape and thickness on conductive line patterns observed by SEM. Therefore, it was confirmed that the electrical characteristics could be obtained when the average particle size of silver nanoparticles is smaller and the uniformity of the particles is maintained.