• 한국환경복원기술학회지
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• 제9권3호
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• pp.59-75
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• 2006

The vascular plants of this site was listed 360 taxa; 86 families, 229 genera, 311 species, 42 varieties and 7 forms. Specific plant species by floral region were total 40 taxa; 2 taxa(Crypsinus hastatus, Prunus yedoensis) in class V, Patrinia rupestris in class IV, 6 taxa(Elymus mollis, Carex laticeps, Poncirus trifoliata, Melia azedarach var. japonica, Koelreuteria paniculata, Crepiastrum lanceolatum) in class III, Cirsium schantarense in class II, 30 taxa(Lygodium japonicum, Pteris multifida, Phacelurus latifolius, Asparagus cochinchinensis, Ficus erecta, Machilus thunbergii, Zanthoxylum planispinum, Euphorbia esula, Mallotus japonicus, Cayratia japonica, Camellia japonica, Glehnia littoralis, Lysimachia fortunei, Messerschmidia sibirica, Ixeris repens etc.) in class I. The naturalized plants in this site were 14 families, 34 genera, 41 species, 1 varieties, 42 taxa and naturalization rate was 20.3% of all 207 taxa vascular plants. Based on the list of the rare plants by the Forest Research Institute, 2 taxa were recorded in the studied areas; Phacelurus latifolius, Crypsinus hastatus and based on the list of Korean endemic plants, 7 taxa were recorded; Populus tomentiglandulosa, Filipendula glaberrima, Prunus yedoensis, Forsythia koreana, Paulownia coreana, Weigela subsessilis, Carpinus coreana. So, wild plants disturbing ecosystem like Solanum carolinense and Ambrosia artemisiifolia var. elatior have been increasing, it needs continuing control and conservation measures on the plant ecosystem.

• 생약학회지
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• 제34권2호통권133호
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• pp.156-160
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• 2003

$NF-{\kappa}B$ (nuclear factor-kappa B) plays a particularly central role in epidermal biology. It has been established that ultraviolet radiation (UVR) is one of the mechanisms to induce the activation of $NF-{\kappa}B$ in human skin. We previously demonstrated that melanogenic inhibitors may act through the inhibition of $NF-{\kappa}B$ activation in keratinocytes. In order to find another type of melanogenic inhibitors of $NF-{\kappa}B$ activation, various kinds of the extracts from crude drugs $(30\;{\mu}g/ml)$ were preincubated with transfectant HaCaT cells for 3 hrs and then UVR $(60\;mj/cm^2)$ was irradiated. UVR-exposed cells were incubated for another 6 hrs to measure the $NF-{\kappa}B$ activity. $NF-{\kappa}B$ activation was measured with the secreatory alkaline phosphates (SEAP) reporter gene assay using a fluorescence detection method. Among natural products, Lycium chinense, Acanthopanax senticosus, Angelica koreana, Kalopanax pictus and Asparagus cochinchinensis were the most potent inhibitors of $NF-{\kappa}B$ activation by UVR. These observations suggest that some crude drugs might act partially through the modulation of the synthesis of melanotrophic factors to decrease melanogenesis in keratinocytes.

• 한방안이비인후피부과학회지
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• 제17권1호
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• pp.104-125
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• 2004

This study was carried out to investigate the anti-microbial of various herbal extracts on six types of bacteria related to skin diseases and effects of Saussurea lappa extract on dermatitis and acne. The results are followed ; 1. In the experiment on P. acnes using paper disk methods, Eugenia caryophyllata extract made 19mm clear zone, Saussurea lappa extract and Morus alba extract made 13mm and MIC of Morus alba extract and Eugenia caryophyllata extract was below 0.01$\%$. 2. In the experiment on S. aureus, extract of Eugenia caryophyllata, Poncirus trifoliata and Rubus coreanus made 9-10mm clear zone. 3. In the experiment on C. xerosis, Sesamum indicum extract made 16mm clear zone and MIC of that was 0.3$\%$. 4. In the experiment on C. albicans, extract of Cinnamomum cassia, Eugenia caryophyllata and Asparagus cochinchinensis made 9-10mm clear zone. 5. In the experiment on P. ovale, Cinnamomum cassia extract made 25mm clear one, MIC of that was 0.05$\%$. 6. In the experiment on T. mentagrophytes, Cinnamomum cassia extract made 26mm clear zone, extract of Eugenia caryophyllata, Rhizoma kaempferiae, Piper longum, Saussurea lappa and Zingiber officinale made 18-22mm clear zone, MIC of all extracts was below 0.02$\%$. 7. Saussurea lappa extract inhibited 85$\%$ and 28$\%$ of NO production at 50㎍／㎖ and 5 ㎍／㎖ 8. Saussurea lappa extract inhibited activity of COX Ⅱ over 50$\%$ at 10㎍／㎖ 9. Saussurea lappa extract had not radical scavenging activity and Saussurea lappa extract didn't inhibit manifestation of IL-1${\beta}$, IL-6 and TNF-${\alpha}$, and activity of 50- reductase I.

• 한국식품저장유통학회지
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• 제18권4호
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• pp.620-625
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• 2011

당뇨병에 효과가 있는 식품소재의 탐색과 그 소재를 이용한 기능성 빵제품 개발에 관한 연구의 일환으로 당뇨병에 효과가 있다고 알려진 소장흡수 저해효소인 ${\alpha}$-glucosidase를 target로 시중에 유통되는 다양한 생약재를 대상으로 탐색을 하였다. ${\alpha}$-Glucosidase 저해활성을 조사하고자 생약재 200여종을 대상으로 물층과 메탄올 층으로 구분하여 탐색한 결과 물층에서는 황기(70.9%)가, MeOH층에서는 구인(72.9%)이 70%이상의 강력한 저해효과를 나타났으며 60%이상으로는 물층에서는 육두구(69%), 상백피(66.9%), 오미자(65%), 삼칠(63.9%), 전호(62.9%), 천문동(62.1%), 정공등(60.9%), 호장근(60.7%), 창출(60.2%), 소자(60.2%)등 이었으며, MeOH층으로는 만삼(67.8%), 도인(67.6%), 방기(63.5%), 동규자(61.6%) 순으로 활성효과를 나타내었으며 50%이상의 저해효과를 보인 것으로는 물층에서는 황정(59.8%), 신곡(59.7%), 택사(59.5%), 의인(59.2%), 세신(59.0%), 시호(53.0%)를 포함한 31여종, MeOH층에서는 사군자(58.8%), 구기자(58.3%), 과루인(58.0%), 백자인(55.9%), 백강잠(55.6%), 계내금(55.4%), 독활(55.3%), 구척(52.7%), 대극(52.7%), 백편두(52.5%) 10종이 저해효과를 나타내었다. 따라서 당뇨병 환자의 기능성 소재로 개발하는데 기초 자료가 될 것으로 기대된다.

• 한국환경생태학회지
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• 제23권2호
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• pp.177-186
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• 2009

변산반도국립공원 작은당 일대의 식물상은 50과 88속 98종 6변종 1품종으로 총 105종류가 확인되었으며, 이중 목본식물은 31종류(29.5%), 초본식물은 74종류(70.5%)로 구분되었다. 식물상 중 희귀식물에는 모새달(보존우선순위: 194번), 쥐방울덩굴(151번), 모감주나무(115번), 갯방풍(203번) 등 4종류가 확인되었다. 특산식물에는 민(좀)땅비싸리와 서울제비꽃이 확인되었으며, 국외반출 승인대상 식물은 희귀식물과 동일하게 확인되었다. 또한 식물구계학적 특정식물에는 V등급과 IV등급 및 II등급에 해당하는 식물군은 출현하지 않았으며, III등급에는 갯그령, 솔장다리, 모감주나무 등의 3분류군, I 등급에는 갯쇠보리, 모새달, 통보리사초, 천문동, 쥐방울덩굴, 갯장군채, 장구밥나무, 갯방풍, 갯메꽃, 모래지치, 순비기나무, 참골무꽃, 해국 등의 13분류군으로 도합 16분류군이 확인되었다. 귀화식물에는 큰이삭풀, 미국자리공, 다닥냉이, 아까시나무, 달맞이꽃, 큰도꼬마리 등 6과 10속 10종류가 확인되었으며, 귀화율은 전체 105종류의 식물상 중 9.5%로 분석되었다. 군락은 사구와 배후습지로 구분하여 피복율과 상대우점치를 분석하였으며, 사구지역은 순비기나무군락, 배후습지는 모새달군락으로 구분되었다. 작은당은 국립공원인 변산반도사무소에서 사구 식물관찰지로 지정관리하고 있으며, 이를 보존하기 위해서는 탐방 예약제나 사구식물에 대한 교육과 홍보 등의 체계적인 관리대책이 요망된다.