• Journal of the East Asian Society of Dietary Life
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• v.23 no.6
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• pp.799-809
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• 2013

This study was performed to determine the optimal composition of a makgeolli administered nuruk, water and Asparagus cochinchinensis. The experiment was designed base on BBD (box-behnken design), and an evaluation was carried out by means of RSM (response surface methodology), which included 15 experimental points with 3 replicates for the three independent variables nuruk, water and Asparagus cochinchinensis. The nuruk levels were tested in a range of 10~30 g, the water levels in a range 120~180% and Asparagus cochinchinensis was tested within a range of 2~6% by the weight of cooked-rice. Using the F-test, brix and appearance were expressed as a linear model, whereas the pH, acidity, DPPH radical scavenging, L-value, savory taste, taste, fresh aroma, after swallow and overall acceptability were expressed as a quadratic model. Increased amount of Asparagus cochinchinensis led to the reduction of the sensory scores for appearance, flavor, taste, texture and overall quality. The optimum formulation by numerical and graphical method were similar: nuruk 24.50 g, water 174.95% and Asparagus cochinchinensis 2.40%.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2023.04a
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• pp.39-39
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• 2023

The purpose of this study is to investigate vasodilatation effect of complex saponin separated from Scrophulariae radix, Asparagus cochinchinensis and Liriope platyphylla mixture extract on rabbit carotid artery. In this study, to determine vasodilatation effect of complex saponin separated from Scrophulariae radix, Asparagus cochinchinensis and Liriope platyphylla mixture extract on rabbit carotid artery, arterial rings with intact or damaged endothelium were used for experiment using organ bath, and were contracted by endothelin. complex saponin, major active constituents of Scrophulariae radix, Asparagus cochinchinensis and Liriope platyphylla mixture extract, showed a moderate vasodilatation effect on the basilar arteries of rabbits. Therefore, treatment with complex saponin separated from Scrophulariae radix, Asparagus cochinchinensis and Liriope platyphylla mixture extract may selectively accelerate cerebral blood flow through dilatation of the basilar artery. Theseis result suggest a potential role of complex saponin separated from Scrophulariae radix, Asparagus cochinchinensis and Liriope platyphylla mixture extract as source of vasodilatation agent.

• Korean Journal of Oriental Medicine
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• v.14 no.1
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• pp.129-135
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• 2008

Phylogenetic relationship and DNA polymorphism among local populations of the Asparagus cochinchinensis have been investigated based on nuclear ribosomal DNA ITS sequences and RAPD analysis in Korea. In result, two genetically distinct groups of local populations except Geoje were recognized by the phylogenetic tree both in rDNA-ITS and RAPD. One was called 'western coast group' that includes the Buan 1, 2 and Taean and the other was 'southern coast group' that includes Haenam, Yeosu and Namhae. Thus, the geographical relationship of Asparagus cochinchinensis was two well-typified clades. These results suggest that the geographical genetic variation of Asparagus cochinchinensis is closely connected with the slow and long period of propagation via the coast in Korean Peninsula.

• Advances in Traditional Medicine
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• v.1 no.1
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• pp.89-96
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• 2000

A human hepatoma cell line, Hep G2 cells are a reliable for the study of alcohol-induced hepatotoxicity. In this study, the author investigated the effect of an aqueous extract of Asparagus $cochinchinensis_{MERRIL}$ (Liliaceae) roots (ACAE) on ethanol (EtOH)-induced cytotoxicity in Hep G2 cells. ACAE dose-dependently inhibited the EtOH-induced tumor necrosis $factor-{\alpha}\;(TNF-{\alpha})$ secretion. ACAE also inhibited the EtOH and $TNF-{\alpha}-induced$ cytotoxicity. Furthermore, the author found that ACAE inhibited the $TNF-{\alpha}-induced$ apoptosis of Hep G2 cells. These results suggest that ACAE may prevent the EtOH-induced cytotoxicity through inhibition of the apoptosis of Hep G2 cells.

• Microbiology and Biotechnology Letters
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• v.43 no.4
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• pp.367-372
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• 2015

This study was aimed at determining the antioxidant and antimicrobial effects of solvent extracts from Asparagus cochinchinensis. The Asparagus cochinchinensis was extracted with water, methanol, ethanol, n-hexane, dichloromethane, ethyl acetate, and ether. The antimicrobial activity of these extracts was determined by modified well diffusion methods against 4 species of respiratory disease bacteria (Staphylococcus aureus, Escherichia coli, Staphylococcus epidermidis, and Pseudomonas aeruginosa). In addition, the amount of total polyphenol and flavonoid content, and antioxidant activity was evaluated. Ethyl acetate extract of A. cochinchinensis exhibited higher antimicrobial activity against tested microorganisms than water, methanol, ethanol, n-hexane, dichloromethane, and ether extracts. For antioxidant activity, the ethyl acetate extract of A. cochinchinensis exhibited a notable effect on the scavenging of superoxide against DPPH ($IC_{50}=3.81mg/ml$). Finally, the total polyphenol and flavonoid contents were $14{\pm}0.7mg/g$, and $0.50{\pm}0.13mg/g$, respectively. These results can be regarded as basic research into A. cochinchinensis for the prevention of respiratory diseases. The results indicate that A. cochinchinensis may be utilized as a nutraceutical for respiratory diseases when the physiologically active substances of A. cochinchinensis are increased by further study.

• Korean Journal of Medicinal Crop Science
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• v.11 no.3
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• pp.212-215
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• 2003

There were so many Asparagus cochinchinensis (Lour.) Merr. in the past in Korea. Now a day, it is under diminishing circumstance because of over exploitation for pharmacy materials. The amount of domestic market demand of it was imported. The autochthonous planting areas were mainly surveyed along coastal region and island. Autochthonous A. cochinchinensis was mainly distributed in sea shore below 1km from sea and founded 26 regions among 45 surveyed regions. Northern and eastern limited distribution of A. cochinchinensis was $N36^{\circ}15'$ in the west coast and $E128^{\circ}02'$ in the south coast of Korean peninsula, respectively. But it was not founded in the east coastal region. Dominant vegetation of surveyed area was pine with shrub. The number of tuberous roots of A. cochinchinensis growing in good light penetration was more than growing in bad light penetration.

• Korean Journal of Medicinal Crop Science
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• v.17 no.2
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• pp.125-132
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• 2009

This study was carried out to investigate the distribution of native Asparagus cochinchinensis and ecological characteristic in South Korea. Natural vegetative areas were investigated at 5 areas; Taean, Buan, Geoje, Namhae and Jindo. In this study, the $5m{\times}5m$ quadrat was established for recording coverage and appearance species by phytosociological method. The flora of the studied area in native habitats were listed as 130 species. The native habitats was classified into Pinus thunbergii community and typical community. Two communities were located in a coastal cliff and have been destroyed. Therefore Asparagus cochinchinensis native habitats must be protected by regulation. In the studied sites, soil pH, organic matter, nitrogen, available phosphorus, exchangeable K, exchangeable Ca, exchangeable Mg and cation exchange capacity were ranged from $5.1{\sim}5.7%$, $1.77{\sim}3.59%$, $0.19{\sim}0.54%$, $5.4{\sim}18.7$ (mg/kg), $0.24{\sim}0.48$ (cmol+/kg) $0.76{\sim}2.83$ (cmol+/kg), $3.11{\sim}6.22$ (cmol+/kg) and $8.7{\sim}24.5$(cmol+/kg), respectively.

• Korean Journal of Medicinal Crop Science
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• v.18 no.2
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• pp.93-97
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• 2010

Cultural practices of Asparagus cochinchinensis in highland area were performed for a potential medicinal crop. These studies were examined to propagation methods, planting densities, nitrogen treatments, and cropping years. The results are summarized as follows. The adequate number of buds per tuberous root was 4 for vegetative propagation because the number of tuberous root harvested was 16.8 and the yield was also the highest, exhibiting 1,060 kg/10a. The suitable planting time for vegetative propagation was later than early April. If the earlier tuberous roots were planted, the less they emerged. The highest emergence rate was obtained from the planting density of $30{\times}20cm$ as 97.2% while the yield was highest in the $30{\times}15cm$ density, exhibiting 1,883 kg/10a with emergence rate at 94.9. It seemed that the higher planting density promoted plant height growth and yield in Asparagus cochinchinensis. The highest fresh weight was recorded at 6 kg/10a of nitrogen fertilizer into the sandy loam soil compared to the level of 0, 3, 9 kg/10a. The yield was increased with cropping years. However, the proper harvesting time was the second year of cultivation because the rate of weight increase was maximized in the 2-year-old tuberous root. The yield in the third year was decreased as compared to that of the second year.

• Journal of the Korean Society of Food Science and Nutrition
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• v.37 no.1
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• pp.16-19
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• 2008

Bone mass in adults decreases with age because of the imbalance between the rate of bone formation and resorption. We performed this study to investigate whether Asparagus cochinchinensis (Lour.) Merr. (ACAE) plays a role in osteoblasts differentiation and osteoclasts formation. Ethanol extract of ACAE showed increase in the differentiation and alkaline phosphatase activity of osteoblasts. Also, it decreased the number of tartrate-resistant acid phosphatase (TRAP)-positive multinucleated cells (OCLs) and TRAP activity. Therefore, ACAE has the potential to prevent bone-related diseases such as osteoporosis by increasing the differentiation of osteoblasts and reducing both the number and activity of osteoclasts.

• Food Science of Animal Resources
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• v.38 no.6
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• pp.1196-1202
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• 2018

The objective of this study was to determine the antioxidant activity of gamma-irradiated Asparagus cochinchinensis (Asparagi radix) (Lour.) Merr. Extract (ARE) and its inhibition effect on food lipid oxidation using emulsion-type pork sausage as a model. ARE was prepared from dried Asparagi radix root and ARE solution (1.0 g/mL) was gamma-irradiated with designated doses at 5, 10, and 20 kGy. Antioxidant activity of ARE solution was determined by measuring 1,1-diphenyl-e-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-9-sulphonic acid) (ABTS) radicals. Activities of DPPH and ABTS radicals were decreased, whereas total phenolic contents increased after gamma irradiation with a dose dependence. Addition of gamma-irradiated ARE dose-dependently retarded lipid oxidation of emulsion-type pork sausage during storage at $4^{\circ}C$. These results indicated that gamma-irradiated ARE might have antioxidant activity more than non-irradiated ARE due to increase of the content of polyphenolic compounds by ionizing radiation.