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SHRIMP U-Pb Age Determination for the Gneissic Country Rocks Around the Hongcheon Iron-REE Depsosit (홍천 철-희토류 광상의 편마암질 주변암에 대한 SHRIMP U-Pb 연령측정)

  • Kim, Myoung-Jung;Park, Kye-Hun;Koh, Sang Mo;Yi, Keewook
    • The Journal of the Petrological Society of Korea
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    • v.22 no.4
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    • pp.299-305
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    • 2013
  • It is well known that the Hongcheon iron-rare earth deposit is composed of carbonatite-phoscorite complex. We conducted zircon U-Pb age determination for the gneissic country rocks of this deposit. As the result we obtained ca. 1830 Ma, which is somewhat younger than igneous and metamorphic ages of ca. 1870 Ma generally reported from the Gyeonggi massif, suggesting further investigations for the timing and evolution of the Paleoproterozoic activities of the Gyeonggi massif.

The Mechanism of the Neurotoxicity Induced by Cadmium (카드뮴의 중추신경계 독성유발 기전)

  • Lee Jong-Wha;Jang Bong-Ki;Park Jong-An;Park Jong-Young;Kim Wan-Jong;Woo Ki-Min
    • Environmental Analysis Health and Toxicology
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    • v.19 no.3
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    • pp.279-286
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    • 2004
  • Although numerous studies have shown that cadmium disturbs the normal biological processes in central nervous system, the mechanism of toxicity is not well understood. The present study has investigated the effect of cadmium on oxidative stress, Na$^{+}$K$^{+}$ ATPase activity and the aggregation of amyloid beta peptide ($\beta$-amyloid) in neuronal cell line, HT22 cell. LC$_{5}$ and LC$_{50}$ of cadmium for HT22 cell resulted from MTT assay was 4.1 uM and 9.5 uM, respectively. Cadmium (2 to 8 uM) dose-dependently increased the lipid peroxidation and decreased the content of glutathione. Cadmium 4 uM showed a significant decrease in Na$^{+}$/K $^{+}$ ATPase activity as compared with control group. The aggregation of $\beta$-amyloid was accelerated in a dose-dependent manner by the treatment with 2 to 8 uM cadmium. These results suggest that the neurotoxicity of cadmium can be mediated by the increase in oxidative stress and decrease in Na$^{+}$/K$^{+}$ ATPase activity.se activity.

Low-Power Operation Method of Thermal-Energy Harvesting Sensor Circuit (Thermal Energy Harvesting용 센서회로의 저전력 구동 방법)

  • Nam, Hyun Kyung;Pham, Van Khoa;Tran, Bao Son;Nguyen, Van Tien;Min, Kyeong-Sik
    • Journal of IKEEE
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    • v.22 no.3
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    • pp.842-845
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    • 2018
  • In this paper, we propose low-power operational methods for thermal-energy-harvesting sensor circuits. Here, the amount of harvested current has been measured as low as 8uA. However the DC power consumption of the sensor circuit is known to consume much larger than 8uA. Thus, We propose the hardware-based power gating and software-based active/sleep timing control schemes, respectively, for controlling the power consumption of sensor circuit. In the hardware-based power gating scheme, if the ratio of Toff/Ton is larger than 22, the sensor can consume less than 8uA. For the software-based active/sleep control scheme, if the ratio of Tslp/Tact is larger than 3, we can suppress the current consumption below 8uA. The hardware-based and software-based schemes proposed in this paper would be helpful in various applications of energy-harvesting sensor circuits, where the power consumption is limited by an amount of harvested energy.

Tumor Segmentation in Multimodal Brain MRI Using Deep Learning Approaches

  • Al Shehri, Waleed;Jannah, Najlaa
    • International Journal of Computer Science & Network Security
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    • v.22 no.8
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    • pp.343-351
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    • 2022
  • A brain tumor forms when some tissue becomes old or damaged but does not die when it must, preventing new tissue from being born. Manually finding such masses in the brain by analyzing MRI images is challenging and time-consuming for experts. In this study, our main objective is to detect the brain's tumorous part, allowing rapid diagnosis to treat the primary disease instantly. With image processing techniques and deep learning prediction algorithms, our research makes a system capable of finding a tumor in MRI images of a brain automatically and accurately. Our tumor segmentation adopts the U-Net deep learning segmentation on the standard MICCAI BRATS 2018 dataset, which has MRI images with different modalities. The proposed approach was evaluated and achieved Dice Coefficients of 0.9795, 0.9855, 0.9793, and 0.9950 across several test datasets. These results show that the proposed system achieves excellent segmentation of tumors in MRIs using deep learning techniques such as the U-Net algorithm.

A ROENTGENOCEPHALOMETRIC STUDY ON THE CRANIOFACIAL RELATIONSHIPS IN THE CHILDREN WITH PRIMARY DENTITION (유치열기아동의 안면두개에 관한 두부방사선학적 연구)

  • Suhr, Cheong-Hoon
    • The Journal of the Korean dental association
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    • v.22 no.11 s.186
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    • pp.947-951
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    • 1984
  • The present study was performed to establish the cephalometric standards of linear measurements in Hellman dental age II C groups of Korean on the roentgenocephalometry. The subjects consisted of 21 males 31 females with normal occlusion and acceptable profile. The major conclusions were as follows. 1. The means and standard deviations of the measurements in males and females were made. 2. No sex difference was made in all items, except in U₁-Y and U₁-X.

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Review on the Adhesiveness of Consumer Arbitration Agreements: U.S. Laws (소비자 중재합의의 부합계약성에 관한 검토 - 미국법을 중심으로 -)

  • Ha, Choong-Lyong
    • Journal of Arbitration Studies
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    • v.22 no.3
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    • pp.47-69
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    • 2012
  • This paper investigates the U.S. courts'attitudes toward the legal doctrine of adhesion contracts, which have been employed as contract defenses by individual consumers who have entered into consumer arbitration agreements with businesses. Some requirements have been added to the sole adhesiveness of the arbitration clause that can invalidate the arbitration clause, including unconscionability and unreasonable harshness. It seems that the U.S. courts have moved toward a more tightened stance in evaluating the validity of consumer arbitration clauses, favoring consumer arbitration.

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Protective Effect of EGCG Against Reactive Oxygen Species-induced Stress

  • Ha, Jung-Sun;Kim, Jeong-Hee
    • International Journal of Oral Biology
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    • v.30 no.3
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    • pp.77-84
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    • 2005
  • EGCG[(-)-epigallocatechin gallate], is a major component of green tea has been considered as a major antioxidant constituent. It has been considered as potential chemopreventive and chemotherapeutic agents. However, very little is known about the cellular actions by which EGCG mediates its therapeutic effects. Various aspects of antioxidant activity of EGCG were evaluated in this study. EGCG itself did not show significant cytotoxicity. Significant 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity was observed in all ranges of concentration ($0.8-100{\mu}g/ml$) used in this study. Protective effect of EGCG against hydrogen peroxide induced cell death was observed. Relatively high lipid peroxidation inhibitory activity were detected ($IC_{50}$ was about $20{\mu}g/ml$). EGCG also dose-dependently enhanced the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) in V79-4 cells. In concentrations of $100{\mu}g/ml$ of EGCG, activities of SOD, CAT and GPX were measured as 36.9 U/mg of protein, 22.9 U/mg of protein and 17.8 U/mg of protein, respectively. When these values were compared with those of the control groups (24.9 U/mg of protein, 14.9 U/mg of protein and 11.7 U/mg of protein), the relative increases were calculated as 48, 54 and 52%, respectively. Taken together, our findings suggest that EGCG can act as an antioxidant by scavenging radicals and enhancing antioxidant enzyme activities.

Relationship between Lead Levels in Blood and Urine and Laboratory Test Values among Lead Exposed Workers (저농도 연 폭로근로자들의 혈중 및 요중 연량과 생화학적 검사치들 간의 관련성)

  • 김종숙;정용준;조영채
    • Journal of environmental and Sanitary engineering
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    • v.18 no.1
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    • pp.30-40
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    • 2003
  • The study subjects included the workers who were estimated to have been exposed in a low density of lead-laden glaze from pottery manufacturers. They were evaluated in terms of PbB and PbU as indices of lead concentration in the body, and Hb, Hct, ALAD, and FEP as indices of biochemical lead poisoning. Consequently, the study results revealed the relationship between each of indices and its effectiveness to indicate the degree of occupational lead exposure. 1. The mean of PbB was $22.85{\;}{\mu}g/d{\ell}$(range; $4.2~44.7{\;}{\mu}g/d{\ell}$) and PbU $45.69{\mu}g/d{\ell}$(range; $6.7~87.5{\mu}g/d{\ell}$), to indicate the level of lead exposure in the subjects. 2. While there was a high, linear correlation between PbB, PbU and FEP (r=0.835, r=0.855, respectively), a low correlation existed between PbB and ALAD(r=-0.240). 3. While there was a high, linear correlation between PbU and FEP(r=0.825), a low correlation existed between PbU and ALAD(r=-0.352). The above results suggest that FEP can be used as a highly useful biochemical index of lead poisoning, based on its high correlation with PbB and PbU indicating lead concentration in the body.