Journal of environmental and Sanitary engineering (환경위생공학)

Korean Society for Environmental Sanitary Engineers (대한환경위생공학회)
권호 표지

Relationship between Lead Levels in Blood and Urine and Laboratory Test Values among Lead Exposed Workers

저농도 연 폭로근로자들의 혈중 및 요중 연량과 생화학적 검사치들 간의 관련성

  • 김종숙 (충남대학교 보건대학원) ;
  • 정용준 (충남대학교 의과대학 예방의학교실) ;
  • 조영채 (충남대학교 의과대학 예방의학교실)
  • Published : 2003.03.01
Download PDF
⟨ Previous Next ⟩

Abstract

The study subjects included the workers who were estimated to have been exposed in a low density of lead-laden glaze from pottery manufacturers. They were evaluated in terms of PbB and PbU as indices of lead concentration in the body, and Hb, Hct, ALAD, and FEP as indices of biochemical lead poisoning. Consequently, the study results revealed the relationship between each of indices and its effectiveness to indicate the degree of occupational lead exposure. 1. The mean of PbB was $22.85{\;}{\mu}g/d{\ell}$(range; $4.2~44.7{\;}{\mu}g/d{\ell}$) and PbU $45.69{\mu}g/d{\ell}$(range; $6.7~87.5{\mu}g/d{\ell}$), to indicate the level of lead exposure in the subjects. 2. While there was a high, linear correlation between PbB, PbU and FEP (r=0.835, r=0.855, respectively), a low correlation existed between PbB and ALAD(r=-0.240). 3. While there was a high, linear correlation between PbU and FEP(r=0.825), a low correlation existed between PbU and ALAD(r=-0.352). The above results suggest that FEP can be used as a highly useful biochemical index of lead poisoning, based on its high correlation with PbB and PbU indicating lead concentration in the body.

Keywords

References

  1. 한국의산업의학 v.19 no.1 요량과 요중연, ALA 및 coproporphyrin과의 관계 이세훈;김정만;이병국;이광묵
  2. Heavy metal poisoning in textbook of medicine, 13th ed Flink,E.B.;Cecil,R.(ed.)
  3. Arch Environ Health v.23 Certain biological effects of lead upon the animal organism de Bruin A https://doi.org/10.1080/00039896.1971.10665996
  4. Arch Environ Health v.28 Laboratory diagnosis of increased lead absorption Baloh,R.W. https://doi.org/10.1080/00039896.1974.10666469
  5. Arch Environ Health v.30 Erythrocyte protoporphyrin test for occupational lead exposure Tomokuni,K.;Osaka,I.;Ogata,M. https://doi.org/10.1080/00039896.1975.10666785
  6. Arch Environ Health v.23 Standards for the prevention of occupational lead poisoning Kehoe,R.A. https://doi.org/10.1080/00039896.1971.10665995
  7. Arch Environ Health v.23 Effect of lead on δ-aminolevulinic acid dehydrase activities in red blood cells Haeger-Aronsen B;Abdulla,M.;Fristedt,B.I. https://doi.org/10.1080/00039896.1971.10665995
  8. Arch Environ Health v.29 Biological response and subjective symptoms in low level lead exposure Sakurai,H.;Sugita,M.;Tsuchiya,K. https://doi.org/10.1080/00039896.1974.10666555
  9. Int Arch Occup Environ Health v.38 Free erythrocyte protoporphyrin as an indicator of the biological effect of lead in adult males; III. Behavior of free erythrocyte protoporphyrin in workers with past lead exposure Alessio,L.;Bertazzi,P.A.;Monelli,O.;Toffoletto,F. https://doi.org/10.1007/BF00378618
  10. Clin Chem. v.23 Histroy and background of protoporphyrin testing Labbe,R.F.
  11. 第51回 日本産業衛生學會講演集 ポルフィリン代謝の最近の知識と鉛中毒 左野晴洋
  12. 대한산업의학회지 v.3 no.1 연 폭로수준에 의한 공기중 연 농도와 혈액 중 연 농도간의 상관성 박석건;김광종
  13. 한국산업위생학회지 v.6 no.1 직업적으로 납에 노출된 근로자들의 혈액중 납과 ZPP농도와의 관계 박동욱;백남원;최병순;김태균;이광용;오세민;안규동
  14. 대한산업의학회지 v.10 no.4 우리나라 축전지제조업근로자의 연폭로에 관한 연구 강필규;김용배;안익수;이규종;한구석;안규동;이병국
  15. 한국산업위생학회지 v.8 no.2 일부 남자 정상인의 혈액 및 요중 연 함량 박종안;최주섭;이종화;이석기
  16. 한국산업위생학회지 v.10 no.2 연 노출 근로자들의 혈장 δ-ALAD량과 연 노출지표들과의 관련성 김진호;안규동;이성수;황규윤;김용배;이병국
  17. 순천향대학교 석사학위논문 2차 연제련 노동자들에서 골 중 연량과 혈중 연량과의 관련성 최성우
  18. 産業醫學 v.17 ALADの性狀と加溫效果を用いる鉛瀑露の評價 牛尾洪一;坂井 公;柳原 進;渡邊秀子
  19. J Lab Clin med. v.81 A micromethod for free erythrocyte porphyrin ; the FEP test Piomelli,S.
  20. 北陸公衛誌. v.6 上繪付作業者の鉛による人體 汚染とその建康影響 山田裕一;城戶照彦;尾山光一;坂元倫子;能川造二;小林悅子
  21. 한국의 산업의학 v.7 no.3 연중독의 병리와 증상 이태준
  22. Arch Environ Health. v.37 OSHA criteria for laboratory proficiency in blood lead analysis OSHA https://doi.org/10.1080/00039896.1982.10667534
  23. Arch Environ Health. v.29 Laboratory results of some biological measures in workers exposed to lead Gian,C.S.;Lorenzo,A.
  24. Jpn J Ind Health. v.23 Study on the biological effects of low level lead exposure Yamada,Y.;Kido,T.;Okada,A.;Npgawa,K.;Kobayashi,E.