• Korean Journal of Veterinary Research
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• v.34 no.4
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• pp.815-819
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• 1994

Sixty eight wild rats, Rattus norvegicus, were caught from Seoul city, Kyonggi, Kangwon, Cholla, and Kyongsang-provinces. All sera collected from rats were examined by immunofluorescent test to find antibody against murine typhus. The antibody prevalance to murine typhus was 4.4%(3/68). Sero-positive rate was 12.5%(2/16) in Kyonggi province and 12.5%(1/8) in Cholla province. The sero-positive rate difference between sexes of rats was not recognized. Three Rattus norvegicus having antibody to murine typhus were morphologically classified as subadult with 8.3%(1/12), middle-aged adult with 5.9%(1/17), and old adult with 4.8%(1/21), respectively.

• Current Optics and Photonics
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• v.5 no.4
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• pp.466-476
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• 2021

Frequency-multiplication technology based on microwave photonic principles can be used to generate microwave and millimeter wave signals with a wide frequency tuning range. However, the existing cascaded external modulation frequency-tupling scheme needs to ensure the phase coherence of the modulated Radio Frequency (RF) signal, while the phase modulation directly limits the frequency tuning range of the external modulation frequency multiplication. In this paper, a novel approach for generating an incoherent frequency 12-tupling signal with cascade modulation is proposed. The structure of cascaded dual-parallel Mach-Zehnder modulators can generate a frequency 12-tupling signal. The proposed structure uses no filter or phase control of the RF driving signal. Microwave photonic frequency-tupling was realized under incoherent conditions. Software simulations and experiments validated the proposed structure and proved that it can generate frequency 12-tupling microwave signals under incoherent conditions. Both the frequency range and reliability of the frequency-tupling system has been improved by the proposed structure.

• Journal of agricultural medicine and community health
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• v.15 no.2
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• pp.107-111
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• 1990

A survey was undertaken to evaluate the present status of intestinal infection in army soldiers. Stool specimen of 417 soldiers fixed by SAF solution were collected from a camp located in area of Nakdong river during the period from August to October of 1990. And these stool samples were examined by formalin-ether sedimentation technique once for helminths and protozoan cysts stained with Lugol's iodine solution. The results obtained in this survey were summarized as follows : l) The overall positive rate of intestinal parasite was 18.0%. 2) The egg positive rate of intestinal helminth was 15.1%, : and 11.5% for Clonorchis sinensis. 5.0% for Metagonimus vokogawai, 1.2% for Ascaris lumbricoides 1.7% for Trichiuris trichiura. 0.2% for Taenia sp. 3) The cyst positive rate of intestinal protozoa was 4.1% ; and 1.4% for Entamoeba coli, 1.9% for Giardia lamblia 0.7% for Entamoeba histolytica, 0.5% for Endolimax nana. 4) Most of samples were positive(85.3%) by single species. 10.7% by two species, 2.7% by three species and 1.3% by four species. 5) Infection rate of intestinal parasites among army soldiers decreased distinctly compared with previous data but it is revealed that the infection rate of Clonorchis sinensis among army soldiers in area of Nakdong river is still high in comparison with ever-reported data. 6) SAF fixatives used in this field survey during summertime was useful to conserve protozoan cyst and helminths ova. Also we could examine stool samples directly by formalin-ether sedimentation technique.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.639-643
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• 2013

Aim: Connexin 43 (Cx43) and E-cadherin are important biomarkers related with cancer. Their expression at protein and mRNA levels was here investigated in 50 primary lung carcinoma tissues and 20 samples of adjacent normal tissue of Chinese patients with non-small cell lung cancer (NSCLC). Methods: Protein and mRNA expression were evaluated by ABC immunohistochemistry and RT-PCR. Results: (1) The positive expression rates of Cx43 and E-cadherin protein were higher in the adjacent normal tissues than those in the primary lung carcinoma tissues; (2) the positive expression rates of Cx43 and E-cadherin protein decreased with NSCLC progression; (3) the expression of E-cadherin protein was not related with the pathological type of NSCLC; and (4) the relative quantity of the Cx43 or E-cadherin mRNA expression was correlated with the the histological type, clinical stage, cancer cell differentiation and the lymph node metastasis. Conclusion: The data suggested that the Cx43 and E-cadherin are reduced with NSCLC progression, and might be important biomarkers for judging the metastasis and prognosis.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.14 no.1
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• pp.323-343
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• 2020

With the rapid development of computer and communication techniques, copyright protection of vector geographic data has attracted considerable research attention because of the high cost of such data. A novel adaptive watermark detection algorithm is proposed for vector geographic data that can be used to qualitatively analyze the robustness of watermarks against data addition attacks. First, a watermark was embedded into the vertex coordinates based on coordinate mapping and quantization. Second, the adaptive watermark detection model, which is capable of calculating the detection threshold, false positive error (FPE) and false negative error (FNE), was established, and the characteristics of the adaptive watermark detection algorithm were analyzed. Finally, experiments were conducted on several real-world vector maps to show the usability and robustness of the proposed algorithm.

• International Journal of Advanced Culture Technology
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• v.11 no.4
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• pp.317-321
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• 2023

After 'emphasizing the development of the precision reconnaissance drone' in 2021, North Korea unveiled two strategic drones in July 2023, just two years later. Despite the majority of experts offering negative assessments and stating that "the performance may not be good," North Korea can be seen as having not only enhanced its routine surveillance capabilities through strategic drones but also possessing limited long-range strike capabilities. In other words, although the performance of North Korea's strategic unmanned aerial vehicles (UAVs), namely the 'Satbyol-4' and '9' models, may not match that of U.S. drones, they appear to play a significant role in offsetting North Korea's considerable aerial and surveillance inferiority compared to the joint forces of South Korea and the United States. Based on these trends, North Korea seems to be concentrating on drone development to counterbalance its considerable aerial power and surveillance capabilities deficit compared to the joint forces of South Korea and the United States, especially as the global use of drones continues to increase.

• The Journal of Korean Medical History
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• v.36 no.2
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• pp.13-25
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• 2023

Due to Japanese imperialism's invasion of Korea and the policy of exterminating national culture, many independence activists from Korean medicine participated in the Manchurian Independence Army activities and the fight for freedom. Kang Woo-kyu, who threw a bomb at the governor-General of Korea on September 2, 1919, can be cited as a leader who learned East Asian medicine. Kim Kwanje, who organized a secret organization by opening an East Asian medicine clinic in Gimhae, Gyeongsangnam-do, was involved in the struggle of the medical corps while working as a medical student. He is accused of providing a shelter by treating members of the Uiryeoldan. In 1919, the Manchurian Independence Army unit, which launched the March 1st Movement armed struggle, was established, and those who served as military doctors in various organizations can be found. Park Se-jung, who participated as an independent soldier at the age of 47, treated wounded soldiers and patients as a military doctor. A branch office was also created by raising military funds and participating in the Provisional Government of the Republic of Korea. Jang Hyong was able to raise independent military funds, campaign for the provisional government's independence petition, and lecture across the country mostly disguised as an East Asian medicine doctor, which led to several imprisonments for "fraud charges under the guise of similar medical practices".

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.1
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• pp.191-194
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• 2012

We conducted a case-control study in China to clarify the association between XRCC1-Arg399Gln polymorphism and HCC risk. A total of 150 cases and 158 controls were selected from the the Affiliated Hospital of Qingdao University from May 2008 to May 2010. XRCC1-Arg399Gln polymorphism was based upon duplex polymerase-chain-reaction with the confronting-two-pairprimer (PCR-CTPP) method. All analyses were performed using the STATA statistical package. A significantly increased risk was associated with the Arg/Gln genotype (adjusted OR 1.78, 95%CI=1.13-2.79) compared with genotype Arg/Arg. In contrast, the Gln/Gln genotype had non-significant increased risk of HCC with adjusted OR (95%CI) of 1.69 (0.93-2.66). A significant association was found between positive HBsAg and Arg/Gln, with an OR of 3.43 (95% CI=1.45-8.13). Patients carrying Gln/Gln genotypes showed significantly lower median survival than Arg/Arg genotypes (HR=1.38, 95% CI=1.04-1.84). Further Kaplan-Meier analysis showed decreased median survival in Arg/Gln+Gln/Gln genotype carriers in comparison to Arg/Arg carriers (HR=1.33, 95% CI=1.02-1.76). In conclusion, we observed that XRCC1-Arg399Cln polymorphism is associated with susceptibility to HCC, and XRCC1 Gln allele genotype showed significant prognostic associations.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7331-7333
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• 2013

Aim: To investigate associations of fasting insulin and glucose levels in serum with hepatocellular carcinoma risk. Materials and Methods: This hospital based study was carried out using data retrieved from the register maintained in the Department of Biochemistry of the Nepalese Army Institute of Health Sciences, between 1st December, 2011 and 31st June, 2013. The variables collected were age, fasting plasma glucose, fasting plasma insulin and ALT. Quantitative determination of human insulin concentrations was accomplished by chemiluminescence enzyme immunoassay. Results: Of the total 220 subjects enrolled in our present study, 20 cases were of HCC and 200 were healthy controls. The maximum number of cases of hepatocellular carcinoma in category cutpoints of fasting insulin levels fell in the range of >6.10 ${\mu}U/ml$. The highest insulin levels (>6.10 ${\mu}U/ml$) were seen to be associated with an 2.36 fold risk of HCC when compared with fasting insulin levels of (<2.75 ${\mu}U/ml$). Furthermore, the insulin levels (2.75-4.10 ${\mu}U/ml$) of category cutpoints also conferred a 1.57 fold risk for HCC when compared with lowest fasting insulin levels of (<2.75 ${\mu}U/ml$). Conclusions: The effect of an insulin level in increasing HCC risk appeared consistent, influencing incidence, risk of recurrence, overall survival, and treatment-related complications in HCC patients.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.7
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• pp.4067-4069
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• 2013

Background: The present study was undertaken to establish any correlation of elevated levels of CA19-9 with tumor stage or grade of urothelial carcinoma. Materials and Methods: This hospital based study was carried out in the Department of Biochemistry of Nepalese Army Institute of Health Sciences between $1^{st}$ July 2012 and $31^{st}$ December 2012. Approval for the study was obtained from the institutional research ethical committee. CA19-9 was assayed with an ELISA reader for all cases and expressed in U/ml with 37U/ml taken as the cut-off upper value for normal. Results: Out of 20 cases enrolled, 15 were of urothelial carcinoma and the remaining 5 were controls. There was marked difference between the mean values of CA19-9 in cases $40.2{\pm}19.3U/ml$ of urothelial carcinoma and controls $7.98{\pm}7.34U/ml$. The number of cases in Ta, TI, T2, T3, T4 stages of urothelial carcinoma were 2, 6, 3, 3, 1 respectively. The percentage rise in CA19-9 was less with low grade tumors (22.2%) when compared with high grade tumors (66.6%) (p value $0.001^*$). The percentage of rise in CA19-9 for muscle invasive tumors was very high when compared to superficial tumors. Similarly, the percentage of rise in CA19-9 for metastatic disease was very high when compared to non-metastatic disease and it was found statistically significant (p value $0.001^*$). Conclusion: Serum CA19-9 levels predicts the prognosis of urothelial carcinoma as it is almost invariably raised in tumors having metastatic spread.