• Journal of Korean Neurosurgical Society
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• v.57 no.6
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• pp.432-435
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• 2015

Moyamoya disease is a unique cerebrovascular disorder characterized by idiopathic progressive stenosis at the terminal portion of the internal carotid artery (ICA) and fine vascular network. The aim of this review is to present the clinical application of quantitative digital subtraction angiography (QDSA) in pediatric moyamoya disease. Using conventional angiographic data and postprocessing software, QDSA provides time-contrast intensity curves and then displays the peak time ($T_{max}$) and area under the curve (AUC). These parameters of QDSA can be used as surrogate markers for the hemodynamic evaluation of disease severity and quantification of postoperative neovascularization in moyamoya disease.

• Advances in pediatric surgery
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• v.3 no.1
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• pp.77-82
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• 1997

The association of pyloric atresia and epidermolysis bullosa(EB) in newborn is rare and inheritant as an autosomal recessive trait. We report a newborn girl with pyloric atresia and epidermolysis bullosa. Blisters were noted on her skin at birth, especially in pressure-exposed area, and later on the oral mucosa. Junctional epidermolysis bullosa was confirmed by light microscopy and electron microscopy. Radiography revealed pyloric atresia. Segmental resection of 1.5 cm and gastroduodenostomy were carried out at 4 days of age. Protein loosing enteropathy developed after oral feeding. The frequency of episodes of nonscarred blisters and the severity and duration improved significantly with time. The protein loosing enteropathy was persistent, and at 1 year of age, her growth is markedly retarded.

• Journal of the Korea Society of Computer and Information
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• v.21 no.1
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• pp.115-123
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• 2016

In this study, we collect various side effect pairs which are appeared frequently at many drugs, and select side effect pairs that have higher severity. For every selected side effect pair, we extract common genetic networks which are shared by side effects' genes and drugs' target genes based on PPI(Protein-Protein Interaction) network. For this work, firstly, we gather drug related data, side effect data and PPI data. Secondly, for extracting common genetic network, we find shortest paths between drug target genes and side effect genes based on PPI network, and integrate these shortest paths. Thirdly, we develop a classification model which uses this common genetic network as a classifier. We calculate similarity score between the common genetic network and genetic network of a drug for classifying the drug. Lastly, we validate our classification model by means of AUC(Area Under the Curve) value.

• Journal of Biomedical Engineering Research
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• v.16 no.2
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• pp.121-128
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• 1995

Information about retinal blood vessels can be used in grading disease severity or as part of the process of automated diagnosis of diseases with ocular menifestations. In this paper, we address the problem of detecting retinal blood vessels and optic disk (papilla) in eye-fundus images. We introduce an algorithm for feature extraction based on Fuzzy Clustering algorithm (fuzzy c-means). A method of finding the optic disk (papilla) is proposed in the eye-fundus images. Additionally, the inrormations such as position and area of the optic disk are extracted. The results are compared to those obtained from other methods. The automatic detection of retinal blood vessels and optic disk in the eye-rundus images could help physicians in diagnosing ocular diseases.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.4
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• pp.141-150
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• 2019

Objectives : The purpose of this study is to report the effect of Korean Medicine on erythrodermic psoriasis. Methods : We administered herbal medicine to three patients who showed psoriasis. There were no other treatment except herbal medicine. And we evaluated the results by Psoriasis Area and Severity Index(PASI). Results : After the treatment three patients showed improvements in PASI. PASI of patient 1 changed from 26.2 to 0.3 after 149 days; patient 2 from 40.5 to 5.8 after 106 days; patient 3 from 31.6 to 0 after 294 days. Conclusions : The results suggest that herbal medicine can be an effective treatment for erythrodermic psoriasis patients.

• The Journal of Korean Medicine
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• v.36 no.3
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• pp.126-134
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• 2015

Objectives: The purpose of this study is to present four case reports on the treatments of psoriasis initiated after acute tonsillitis. Methods: We administered herbal medicine to four patients who showed psoriasis symptoms after acute tonsillitis and evaluated the results by Psoriasis Area and Severity Index(PASI). Results: After the treatment all four patients showed improvements in PASI. PASI of patient 1 changed from 27.7 to 1.8; patient 2 from 19.8 to 0.4; patient 3 from 28.8 to 0; patient 4 from 6.9 to 0. Conclusions: The results suggest that herbal medicine can be an effective treatment for psoriasis of which the occurrence is related to acute tonsillitis.

• Journal of Veterinary Clinics
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• v.4 no.1
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• pp.423-432
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• 1987

The present studies were undertaken in attempt to investigate the therapeutic effect of ethanol in dogs intoxicated with ethylene glycol Three dogs treated with ethylene glycol and other three dogs with ethylene glycol plus 20% ethanol orally were examined on clinical signs, endoscopic views, histopathological findings, and autopsy findings respectively. The results obtained were summarized as fellows : 1. The clinical sings and their severity of dogs intoxicated with ethylene glycol were time related and progressed from vomiting, depression, thirsty, tachycardia, tachypnea, convulsiot ataxia, melena, uremia and coma, but clinical signs of dogs treated with ethylene glycol and ethanol simultaneously only stowed vomiting and thirsty. 2. In the gastroscopic view, the dogs intoxicated with ethyelne glycol showed edematous, hyperemia, errosive and ulcerative lesions in the fundus and body area but the dogs treated with ethylene glycol and ethanol simultanously showed edematous and hyperemic lesions. 3. Oral treatment of ethanol with ethylene glycol simultaneously have reduced the signs of EG intoxications in dogs.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.3
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• pp.145-154
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• 2014

Objective : The purpose of this case study is to report the effectiveness of Sojongyuryang-tang gagambang in respect of spleen dampness on 3 psoriasis patients who had unhealthy dietary habit. Methods : PASI(psoriasis area and severity) score was used to check the prognosis of 3 psoriasis patients, who have been treated with Sojongyuryang-tang gagambang and acupuncture. Results : PASI score decreased as a result of Sojongyuryang-tang gagambang treatment in 3 psoriasis patients. Conclusion : Sojongyuryang-tang gagambang can be effective treatment for the unhealthy diet related psoriasis when diagnosed as spleen dampness.

• Korean Management Science Review
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• v.28 no.3
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• pp.73-82
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• 2011

Basel II advanced measurement approaches for operational risk need to estimate the frequency and severity distribution of operational losses. Due to lack of internal loss data, the estimation is impossible in many cases and so external loss data might be used by scaling on asset or gross income. To get around lack of loss data, scenario analysis combined with loss distribution approach can be useful in calculating the capital charge of operational risk. However, scenario based loss distribution approach requires much time and effort. Instead we may apply the analytic hierarchy process to measure operational risk of financial institutions. The analytic hierarchy process combined with loss distribution approach is to estimate the capital charge of operational risk in other areas based on the operational VaR in an area with sufficient loss data. AHP provides a tool for timely measurement of operational risk in this rapidly changing global environment.

• Journal of Korean Medical Ki-Gong Academy
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• v.15 no.1
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• pp.71-88
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• 2015

Objects : The purpose of this case study is to report the effect of Su-Gi therapy with Oriental medical treatments on systemic psoriasis. Methods : The subject is a patient with systemic psoriasis. This patient was treated with Oriental medical treatments and Su-Gi therapy. The improvement of the skin condition is observed by Psoriasis Area and Severity Index (PASI) score. Results : After the treatment, the symptoms of psoriasis were relieved. PASI score of this patient went down from 39.6 to 12.5. Conclusions : This study showed that Su-Gi therapy added with Oriental medical treatment can be an effective choice for systemic psoriasis.