• Title/Summary/Keyword: Araliaceae

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Hyperin, An Aldose Reductase Inhibitor from Acanthopanax senticosus Leaves

  • Lee, Sang-Hyun;Jung, Sang-Hoon;Lee, Yeon-Sil;Shin, Kuk-Hyun
    • Natural Product Sciences
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    • v.9 no.1
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    • pp.4-6
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    • 2003
  • Hyperin from the leaves of Acanthopanax senticosus was tested for its effect on rat lens aldose reductase and demonstrated to exhibit a significant inhibition of rat lens aldose reductase activity with $IC_{50}$ value of $2.63\;{\mu}M$.

Studies on the Constituents of Acanthopanax koreanum $N_{AKAI}$ (I) (섬오갈피나무의 성분연구(成分硏究)(제1보)(第1報))

  • Kim, Young-Ho;Chung, Bo-Sup;Kim, Han-Ju
    • Korean Journal of Pharmacognosy
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    • v.16 no.3
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    • pp.151-154
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    • 1985
  • From the BuOH Fr. of the roots of Acanthopanax koreanum $N_{AKAI}$, we have isolated a lignan glucoside, mp $257{\sim}259^{\circ}$, $C_{34}H_{46}O_{18}$ and it was identified to be (-) syringaresinol diglucoside by spectral data and comparing with authentic samples.

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A Thiazole and Two ${\beta}$-Carboline Constituents from Panax ginseng

  • Park, Jong-Dae;Kim, Man-Wook;Yoo, Seung-Jo;Wee, Jae-Joon
    • Archives of Pharmacal Research
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    • v.11 no.1
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    • pp.52-55
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    • 1988
  • From the ether soluble alkaloidal fraction of Panax ginseng, 4-methyl-5-thiazoleethanol, norharman and barman were isolated. 4-Methyl-5-thiazoleethanol was isolated for the first time from natural resources.

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Phytochemical Studies on the Barks of Acanthopanax senticosus forma intermis (좀가시 오갈피나무의 성분연구)

  • 육창수;김선창;김창종;한덕룡
    • YAKHAK HOEJI
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    • v.35 no.3
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    • pp.147-153
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    • 1991
  • Chemical constituents of fruits, leaves and barks of Acanthopanax senticosus forma inermis were studied. Their fruits have higher contents of crude ash, crude protein, crude fat, fructose and glucose than those of other Acanthopanax species, and contained larger amount of glutamic acid and malic acid among amino acid and organic acid, respectively. The compounds identified from their barks and leaves, were $\beta$-sitosterol and stigmasterol, sesamin, savinin, syringaresinol diglucoside, oleanolic acid, chiisanoside and polyacetytene ($C_9H_{10}O_2$, mp. 62~63).

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Ginsenoside $Rf_{2}$ , a New Dammarane Glycoside from Korean Red Ginseng(Panax ginseng)

  • Park, Jong-Dae;Lee, You-Hui;Kim, Shin-Il
    • Archives of Pharmacal Research
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    • v.21 no.5
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    • pp.615-617
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    • 1998
  • A new dammarane glycoside named ginsenoside $Rf_{2}$ has been isolated from Korean red ginseng (Panax ginseng) and its chemical structure has been elucidated as $6-O-[{\alpha}-L-rham-nopyranosyl (1{\rightarrow}2){\beta}-D-glucopyranosyl]$$dammarane-3{\beta}, 6{\alpa}, 12{\beta}$, 20(R), 25-pentol by chemical and spectral methods.

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Anti-lipid Peroxidation Activity of Acanthopanax var, albeofructus (흰털오갈피나무 추출물의 지질과산화 억제작용)

  • 주시몽;양기숙
    • YAKHAK HOEJI
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    • v.48 no.1
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    • pp.99-103
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    • 2004
  • Acanthopanax species (Araliaceae) has been traditionally used as analgesics, stimulants of immune system, and replenishment of body functions. Acanthopanax divaricatus var. albeofructus is a indigenous plant in Korea. The anti-lipid peroxidation activities of the loaves and root bark extracts of A divaricatus var. albeofructus were determined. Activities of MeOH extracts were examined in vitro and in vivo with control group intoxicated by carbon tetrachloride. Both extracts showed significant inhibitory effects on the lipid peroxidation.

In Vitro Anti-Helicobacter pylori Activity of Panaxytriol Isolated from Ginseng

  • Bae, Eun-Ah;Han, Myung-Joo;Baek, Nam-In;Kim, Dong-Hyun
    • Archives of Pharmacal Research
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    • v.24 no.4
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    • pp.297-299
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    • 2001
  • This study investigated the effect that some polyacetylenes and protopanaxatriol, which were isolated from heated ginseng (family Araliaceae), have on inhibiting Helicobacter pylori (HP) growth. Among the compounds tested, panaxytriol was quite effective in inhibiting HP growth with an MIC of 50 ${\mu}g/ml$. Cinsenoside Rhl and protopanaxatriol weakly inhibited $H^{+}/K^{+}$-ATPase from a rat stomach.

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Screening of Antioxidant Activity of Acanthopanax species in vitro (오가피류의 시험관내 항산화활성 검색)

  • 김지연;양기숙
    • YAKHAK HOEJI
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    • v.47 no.6
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    • pp.361-364
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    • 2003
  • Acanthopanax species (Araliaceae) has been traditionally used as tonic, analgesic, stimulant of immune system, and replenishment of body function. The antioxidant activities of leaf and root bark of Acanthopanax species were determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH) method and thiobarbituric acid reactive substances (TBARS) assay and relative electrophoretic mobility (REM) on human plasma low density lipoproteins (LDL). Acanthopanax divaricatus var. albeofructus and Acanthopanax for. nambunensis showed potent antioxidant activities.