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Optically Active and Organosoluble Poly(amide-imide)s Derived from N,N'-(Pyromellitoyl)bis-L-histidine and Various Diamines: Synthesis and Characterization

  • Faghihi, Khalil;Shabanian, Meisam;Hajibeygi, Mohsen
    • Macromolecular Research
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    • 제17권11호
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    • pp.912-918
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    • 2009
  • An optically active diacid containing the L-histidine moiety was prepared by reacting pyromellitic dianhydride (1,2,4,5-benzenetetracarboxylic acid 1,2,4,5-dianhydride) 1 with L-histidine 2 in acetic acid, and was polymerized with several aromatic diamines 5a-g to obtain a new series of optically active poly(amide-imide)s (PAIs) using two different methods, such as direct polycondensation in a medium consisting of N-methyl-2-pyrrolidone (NMP)/triphenyl phosphite (TPP)/calcium chloride ($CaCl_2$)/pyridine (Py) and direct polycondensation in a tosyl chloride (TsCl)/pyridine (Py)/N,N-dimethylformamide (DMF) system as a condensation agent. The resulting new polymers 6a-g with inherent viscosity was obtained in good yield. The polymers were readily soluble in polar organic solvents, such as N,N-dimethyacetamide (DMAc), N,N-dimethyformamide (DMF), and dimethyl sulfoxide (DMSO). The obtained polymers were characterized by FTIR, specific rotation, elemental analysis as well as $^1$H-NMR spectroscopy and gel permeation chromatography (GPC). The thermal stability of the resulting PAIs was evaluated with thermogravimetric analysis techniques under a nitrogen atmosphere.

Separation of Two Amino Acids by Microemulsion Bulk Liquid Membrane

  • Salabat, Alireza;Sanij, Fereshteh Dehghani
    • Bulletin of the Korean Chemical Society
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    • 제33권10호
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    • pp.3387-3390
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    • 2012
  • In this research work the potentialities of microemulsion bulk liquid membrane for the selective transport of L-tryptophan (L-Trp) and L-tyrosine (L-Tyr) are investigated at 298.15 K. Reversed micelle formed by sodium bis(2-ethylhexyl)sulfosuccinate (AOT) in dichloroethane, was used as mobile carrier to transport amino acids between a source and a receiving aqueous phase. The effects of pH, surfactant concentration and initial amino acid concentration on the extraction efficiency and transfer rate of the amino acids were studied. It is verified that for a mixture of two amino acids, L-Trp can be extracted selectively by using this type of the bulk liquid membrane with optimized condition.

THE EFFECT OF NUMBER OF VIRTUAL CHANNELS ON NOC EDP

  • Senejani, Mahdieh Nadi;Ghadiry, Mahdiar Hossein;Dermany, Mohamad Khalily
    • Journal of applied mathematics & informatics
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    • 제28권1_2호
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    • pp.539-551
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    • 2010
  • Low scalability and power efficiency of the shared bus in SoCs is a motivation to use on chip networks instead of traditional buses. In this paper we have modified the Orion power model to reach an analytical model to estimate the average message energy in K-Ary n-Cubes with focus on the number of virtual channels. Afterward by using the power model and also the performance model proposed in [11] the effect of number of virtual channels on Energy-Delay product have been analyzed. In addition a cycle accurate power and performance simulator have been implemented in VHDL to verify the results.

A new lossless snubber for DC-DC converters with energy transfer capability

  • Esfahani, Shabnam Nasr;Delshad, Majid;Tavakoli, Mohhamad Bagher
    • Smart Structures and Systems
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    • 제25권3호
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    • pp.385-391
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    • 2020
  • In this paper, a new passive lossless snubber circuit with energy transfer capability is proposed. The proposed lossless snubber circuit provides Zero-Current Switching (ZCS) condition for turn-on instants and Zero-Voltage Switching (ZVS) condition for turn-off instants. In addition, its diodes operate under soft switching condition. Therefore, no significant switching losses occur in the converter. Since the energy of the snubber circuit is transferred to the output, there are no significant conduction losses. The proposed snubber circuit can be applied on isolated and non-isolated converters. To verify the operation of the snubber circuit, a boost converter using the proposed snubber is implemented at 70W. Also, the measured conducted Efficiency Electromagnetic Interference (EMI) of the proposed boost converter and conventional ones are presented which show the effects of proposed snubber on EMI reduction. The experimental results confirm the presented theoretical analysis.

Behavior of steel-concrete composite beam using angle shear connectors at fire condition

  • Davoodnabi, Seyed Mehdi;Mirhosseini, Seyed Mohammad;Shariati, Mahdi
    • Steel and Composite Structures
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    • 제30권2호
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    • pp.141-147
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    • 2019
  • Fire is one of the environmental parameters affecting the structure causing element internal forces to change, as well as reducing the strength of the materials. One of the common types of floors in tall steel structures is the steel concrete composite slab. Shear connectors are used in steel and concrete composite beam in various shapes also has played significant role in a burning fire event of building with a steel concrete composite beam. The current study has reviewed the effects of temperature raising on the angle connector behavior through the use of push out tests and monotonic static force. The results have shown (1) the ductility of the samples is acceptable based on EC4 standard; (2) temperature raising has reduced the stiffness; (3) the shear ductility increment; and (4) the shear capacity reduction. Also, the amount of angle shear connector resistance has been decreased from 18.5% to 41% at ambient temperature up to $850^{\circ}C$.

CHARACTERIZATION OF WEAKLY COFINITE LOCAL COHOMOLOGY MODULES

  • Moharram Aghapournahr;Marziye Hatamkhani
    • 대한수학회보
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    • 제60권3호
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    • pp.637-647
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    • 2023
  • Let R be a commutative Noetherian ring, 𝔞 an ideal of R, M an arbitrary R-module and X a finite R-module. We prove a characterization for Hi𝔞(M) and Hi𝔞(X, M) to be 𝔞-weakly cofinite for all i, whenever one of the following cases holds: (a) ara(𝔞) ≤ 1, (b) dim R/𝔞 ≤ 1 or (c) dim R ≤ 2. We also prove that, if M is a weakly Laskerian R-module, then Hi𝔞(X, M) is 𝔞-weakly cofinite for all i, whenever dim X ≤ 2 or dim M ≤ 2 (resp. (R, m) a local ring and dim X ≤ 3 or dim M ≤ 3). Let d = dim M < ∞, we prove an equivalent condition for top local cohomology module Hd𝔞(M) to be weakly Artinian.

Synthesis and Properties of Novel Flame-Retardant and Thermally Stable Poly(amideimide)s from N,N'-(bicyclo[2,2,2]oct-7-ene-tetracarboxylic)-bis-L-amino Acids and Phosphine Oxide Moiety by Two Different Methods

  • Faghihi, Khalil;Hajibeygi, Mohsen;Shabanian, Meisam
    • Macromolecular Research
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    • 제17권10호
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    • pp.739-745
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    • 2009
  • N,N'-(bicyclo[2,2,2]oct-7-ene-tetracarboxylic)-bis-L-amino acids 3a-g were synthesized by the condensation reaction of bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetracarboxylic dianhydride 1 with two equimolars of Lalanine 2a, L-valine 2b, L-leucine 2c, L-isoleucine 2d, L-phenyl alanine 2e, L-2-aminobutyric acid 2f and L-histidine 2g in an acetic acid solution. Seven new poly(amide-imide)s PAIs 5a-g were synthesized through the direct polycondensation reaction of seven chiral N,N'-(bicyclo[2,2,2]oct-7-ene-tetracarboxylic)-bis-L-amino acids 3a-g with bis(3-amino phenyl) phenyl phosphine oxide 4 by two different methods: direct polycondensation in a medium consisting of N-methyl-2-pyrrolidone (NMP)/triphenyl phosphite (TPP)/calcium chloride ($CaCl_2$/pyridine (py), and direct polycondensation in a tosyl chloride (TsCl)/pyridine (py)/N,N-dimethylformamide (DMF) system. The polymerization reaction produced a series of flame-retardant and thermally stable poly(amide-imide)s 5a-g with high yield. The resulted polymers were fully characterized by FTIR, $^1H$ NMR spectroscopy, elemental analyses, inherent viscosity, specific rotation and solubility tests. Data obtained by thermal analysis (TGA and DTG) revealed that the good thermal stability of these polymers. These polymers can be potentially utilized in flame retardant thermoplastic materials.

Production of Recombinant Human Interleukin-11 (IL-11) in Transgenic Tobacco (Nicotiana tabacum) Plants

  • Sadeghi, Abdorrahim;Mahdieh, Majid;Salimi, Somayeh
    • Journal of Plant Biotechnology
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    • 제43권4호
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    • pp.432-437
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    • 2016
  • Interleukin-11 (IL-11) is a cytokine that plays a key regulatory role in the immune system. Recombinant human IL-11 (rhIL-11) exerts a preventative effect against apoptotic cell death and inhibits preadipocyte differentiation. IL-11 also is used to stimulate the bone marrow to produce platelets in order to prevent low platelets that may be caused by chemotherapy. Unfortunately, the high production cost of IL-11 associated. In this study, we investigated the feasibility of transgenic plants for the cost-effective production of rhIL-11. Production of rhIL-11 proteins in whole-plant expression system will be more economical when compared to the current E. coli based expression system. The human rhIL-11 gene was codon optimized to maximize plant host system expression. IL-11 expression vector under the control of a constitutive cauliflower mosaic virus 35S (CaMV 35S) promoter was introduced into tobacco by Agrobacterium-mediated transformation. The 5'-leader sequence (called ${\Omega}$) of tobacco mosaic virus (TMV) as a translational enhancer was added to construct. Transgenic tobacco plants expressing various levels of rhIL-11 protein were generated. Western blotting of the stably transformed lines demonstrated accumulation of the appropriately sized rhIL-11 protein in leaves. This research demonstrated the efficacy of using tobacco as an expression system for the production of rhIL-11.

Characterization of the Growth, Total Lipid and Fatty Acid Profiles in Microalga, Nannochloropsis oceanica under Different Nitrogen Sources

  • Mahdieh, Majid;Shabani, Salimeh;Amirjani, Mohammad Reza
    • 한국미생물·생명공학회지
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    • 제47권1호
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    • pp.11-19
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    • 2019
  • The properties of microalgae as bioresources for biodiesel production can be improved by adding nitrogen sources into the culture medium. Thus, Nannochloropsis oceanica CCAP 849/10 was cultured in f/2 media supplemented with five different forms of nitrogen at $0.88mmol-N\;l^{-1}$ each: ammonium bicarbonate ($NH_4HCO_3$), ammonium sulfate ($(NH_4)_2SO_4$), sodium nitrate ($NaNO_3$), ammonium nitrate ($NH_4NO_3$), and urea. The cell density, lipid content, and fatty acid profile of the microalga were determined after 15 days of cultivation. The growth of N. oceanica based on cell number was lowest in the medium with $NH_4NO_3$, and increased significantly in the medium with $NH_4HCO_3$. Cells treated with $(NH_4)_2SO_4$, and $NH_4NO_3$ produced the highest total lipid contents (i.e., 65% and 62% by dry weight, respectively). The fatty acid profiles of the microalga were significantly different in the various nitrogen sources. The major fatty acids detected in cultures supplemented with $NH_4HCO_3$, $(NH_4)_2SO_4$, $NH_4NO_3$, or urea were C14:0, C16:0, C16:1, C18:0, C18:1, C18:2, C20:5, and C22:6. However, the C16:1 content in the $NaNO_3$-supplemented culture was very low. This study highlights that the nitrogen source can strongly influence lipid production in N. oceanica and its fatty acid composition.