• Biomolecules & Therapeutics
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• v.24 no.6
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• pp.561-571
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• 2016

Marine biosphere is the largest one of the earth and harbors an enormous number of different organisms. Living conditions differ fundamentally from those in terrestrial environment. The production of specific secondary metabolites is an important adaption mechanism of marine organisms to survive in the sea. These metabolites possess biological activities which make them interesting as possible drugs for human. The review presents sources, chemistry, production and pharmacology of FDA approved marine derived pharmaceuticals arranged according to their therapeutic indication. Four of the presently seven approved drugs are used for the treatment of cancer. Each another one is applicated for treatment of viral diseases, chronic pain and to lower triglyceride level in blood. Some other products are of interest in diagnostic and as experimental tools. Besides, this article describes challenges in drug development from marine sources, especially the supply problem.

• Journal of the Semiconductor & Display Technology
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• v.8 no.4
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• pp.89-94
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• 2009

The influence on a stability of thermal plasma has been investigated in an electrode structure of non-transferred plasma torch. The variations of dynamic characteristic of the arc voltage was analyzed and compared in terms of voltage character and nozzle types for both the step-shaped nozzles and magnetic-approved cylindrical nozzle. From the experimental results, an electrode gap, flow rate of arc gas, and currents are considered as major operational parameters. As conclusion, it was assured that a torch with step-shaped nozzles of magnetic-approved type produce the stable plasma jet.

• Journal of Plant Biotechnology
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• v.43 no.2
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• pp.147-150
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• 2016

Global GM crops continue to grow. They have reached 181 million hectares. A total of 28 countries have approved biotech crops for planting. More than 60 countries have approved biotech crops to be imported as food and feed since 1996, meaning that biotech crops are now commonly accepted in those countries. Although biotech crops provide key solutions for the challenge of global food security in the future due to population growth and climate change, there are still some debates on whether biotech crops should be accepted in many countries including Korea. Therefore, it is very important to make people understand that GM crops will provide benefits to both farmers and consumers. In this review, current global status of GM crop development and commercialization are summarized.

• Culinary science and hospitality research
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• v.13 no.3
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• pp.54-67
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• 2007

This study is purposed to find out the relation between the customer loyalty and customer satisfaction factors in Cheonan banquet service. To achieve the objects, customers of banquet companies in Cheonan were selected for a questionnaire survey and a total of 293 valid questionnaires are statistically analyzed, using frequency analysis, factor analysis, reliability analysis and regression analysis. The results can be summarized as follows. First, gender, occupation, family forms showed the statistically different results in the service trust. Second, service trust, menu and traffic factors have been approved to affect the revisit intention of a customer significantly. Third, service trust, menu and facilities factors have been approved to affect the word-of-mouse intention significantly. In summary, banquet managers in Cheonan have to focus on the customer satisfaction factors such as service trust, menu, traffic, facilities to meet the customers' needs.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2016.05a
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• pp.231-232
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• 2016

Configuration Management (CM) is a process of identifying and documenting the characteristics of a Structures, Systems and Components (SSCs), and of ensuring that changes to these characteristics are properly assessed, approved, issued, implemented and verified. There are requirement management, change control, facility configuration information management for CM activities. In order to improve safety of Nuclear Power Plant(NPP), it is necessary to manage change item systematically. Existing CM concept is focused on the NPP in operation. On the other hand, NPP under construction is difficult to efficiently manage the change because of different change process from varoius stake-holders. This research considers method of consolidation change process for NPP to ensure that approved changes are accurately reflected in the design requirements, facility configuration information, and the physical configuration.

• Nuclear Medicine and Molecular Imaging
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• v.40 no.2
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• pp.66-73
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• 2006

Monoclonal antibodies are designed to bind specifically to certain antigen, give therapeutic effect to the target and to be produced in large scale with homogeneity. The monoclonal antibodies conjugated with radionuclide can deliver therapeutic irradiation to the target, and showed successful results in certain malignancies, which is known as radioimmunotherapy. The target-to-background ratio depends on the antigen expression in the target and normal tissues, which is related to the therapeutic efficacy and toxicity in radioimmunotherapy. For the solid tumor beta-ray energy should be high, but lower beta energy is better for the hematological malignancies. I-l31 is widely used in thyroid cancer with low cost and high availability. Labeling monoclonal antibody with I-131 is relatively simple and reproducible. Some preclinical data for the I-131 labeled monoclonal antibodies including acute toxicity and efficacy are available from already published literatures in KIRAMS, physician sponsored clinical trial protocols using Rituximab, KFDA approved anti-CD20 chimeric monoclonal antibody and I-131 were approved by KFDA and currently are ongoing.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.28 no.4
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• pp.182-186
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• 2020

As all flight training institutions in Korea were approved by the Ministry of Land, Infrastructure and Transport (MOLIT) as aviation training organizations (ATO), safety management based on the Aviation Safety Management System (SMS) became mandatory. However, even though safety management using SMS has become mandatory, the performance of aviation safety voluntary report, which is the core of the system, remains low compared to other countries. The current address of SMS, a ATO, is like a watermill without water. The present study is to find out why voluntary aviation safety reports, which is equivalent to water from waterwheel, is underperforming and to suggest ways to revitalize it.

• International Journal of Contents
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• v.18 no.3
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• pp.66-73
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• 2022

The purpose of this study is to evaluate the economic and social impact of the SEP in which the elderly participate by using the blended return on investment (BROI), economic return on investment (EROI), and social return on investment (SROI) research methods. And the sustainable conditions of SEP were confirmed. This study was conducted with one market-type SEP approved by the Korea Elderly Labor Force Development Institute (KLFDI), one preliminary social enterprise approved by Changwon City Hall, and one market-type SEP operated by a social welfare center for the elderly. As a result of the study, it was found that EROI, SROI, and BROI were the highest in the SEP of preliminary social enterprises operated by subsidies in Changwon.However, the difference between EROI and SROI was greatest in the market-type SEP operated by the elderly social welfare center. There was a big difference between economic and social impacts. The social influence of the elderly was evaluated to be higher than the income of the elderly.

• Korean journal of aerospace and environmental medicine
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• v.31 no.1
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• pp.13-16
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• 2021

The coronavirus disease-19 (COVID-19) vaccine is expected to play an important role in stopping the pandemic. Studies show that COVID-19 vaccines are effective at keeping you from getting COVID-19. Getting a COVID-19 vaccine will also help keep you from getting seriously ill even if you do get COVID-19. Efforts to find an effective vaccine against severe acute respiratory syndrome coronavirus 2 have progressed unprecedentedly through active support from public research grants and private-public partnership programs. Clinical studies have been actively conducted, and some vaccines are being vaccinated with approval for urgent use. The WHO has approved and supplied the Pfizer-BioNTech COVID-19 vaccine and the Oxford-AstraZeneca COVID-19 vaccine. In Korea, the Oxford-AstraZeneca vaccine was approved for urgent use, and vaccination began on February 26, 2021. In this paper, the efficacy and side effects of each vaccines and the effect on pilots and air traffic controllers related to COVID-19 vaccination were investigated in terms of aviation medicine.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.30 no.4
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• pp.207-214
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• 2022

교육은 준비, 발표, 적용, 복습 및 평가 순으로 이루어지고, 학습은 경험의 결과로 개인의 지각, 사고, 느낌, 행위의 방식에 의해 변화될 수 있다. 고로 초기 조종사를 양성하는 과정에서 교육과 학습은 안전문화 증진을 위한 매우 중요하다. 항공안전법에서 국내 조종사를 양성하기 위해 전문교육기관(ATO)을 국토교통부로부터 승인을 받아야 하고, 또한 항공안전관리시스템(SMS)도 승인받고 안전관리 활동이 의무화됐다. 조종사가 되기 위한 첫 관문인 학생조종사에게 국가 항공안전관리 정책 및 목표에 부합하도록 달성 가능한 수준의 항공 업무의 안전목표를 수립하고 그 구성원들이 학생조종사에게 안전문화를 형성할 수 있도록 효과적인 교육과 학습 방안을 마련해야 한다. 본 연구는 조종사양성 전문교육기관에서 교육을 받고 있는 학생조종사의 교육과 학습에 따른 단계별 안전의식을 알아보고, 학생조종사가 안전문화를 형성하는데 초기교육과 지속적인 교육을 통해 학습문화을 만들고 도움이 되는지 연구한다.