• Title/Summary/Keyword: Appel's conditions

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Heterocyclization Reaction of 4-(2-Methylaziridin-1-yl)-3-ureidobenzotrifluorides under Appel's Conditions

  • Cho, Hyun-In;Lee, Kee-Jung
    • Bulletin of the Korean Chemical Society
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    • v.24 no.2
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    • pp.189-192
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    • 2003
  • The reaction of 4-(2-methylaziridin-1-yl)-3-ureidobenzotrifluorides 4 with triphenylphosphine, carbon tetrachloride, and triethylamine (Appel's condition) led to the corresponding carbodiimides 5, which underwent intramolecular cycloaddition reaction with aziridine under the reaction condition to give the benzimidazolefused heterocycles, 2,3-dihydro-1H-imidazo[1,2-a]benzimidazoles 8 and 12,13-dihydro-5H-benzimidazo[2,3-b] [1,3]benzodiazepines 9.

Synthesis of 1, 1-Diheteroaryl Ethylenes by a Tandem Appel's Dehydration/Thermal Rearrangement Methodology

  • 이기정;허 열;전종갑
    • Bulletin of the Korean Chemical Society
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    • v.20 no.3
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    • pp.341-344
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    • 1999
  • The hydrazones of 2-acetylfuran, 2-acetylthiophene, and 2-acetylpyrrole, were allowed to react with S-methylthioacetimidate hydroiodide (8) to give azinoureas 10, and the reaction of 10 with Appel's dehydration conditions (triphenylphosphine/carbon tetrachloride/triethylamine) led to the corresponding azinocarbodiimides 11, which underwent thermal rearrangement under the reaction conditions to give 1,1-diheteroaryl ethylenes 13.

A Study for Farmers to Reduce Work Load on the Different Working Conditions (part II) - Cultivating Welsh Onion in the Summer Ground - (농민의 작업환경별 노동부담경감방안에 관한 연구(II) - 여름철 노지에서 대파재배 작업을 중심으로 -)

  • 김명주;최정화
    • Korean Journal of Rural Living Science
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    • v.8 no.2
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    • pp.119-124
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    • 1997
  • In this study we tried to give a decision on propriety of working conditions, to present ideas on reducing work loads, and to grope for efficiency of agricultural works. For this we examined the actual working conditions of cultivating welsh onion in the summer ground. And we improved harmful factors that affect farmer's health by considering results of previous study and farmer's subjective sensation. And we measured. compared, and analyzed the farmer's work loads before and after improvement. The results of this study are as follows ; 1. According to examine the actual working conditions of cultivating welsh onion in the summer ground, farmers have experienced physical and mental chronic fatigue on the basis of farmer's appel to eye - fatigue and sun - burned skin on hot working environment including excessive ultraviolet rays, the rough ground condition, inconsistent arrangement of working stand and sorter, heavy - weared habits, and unsuitable working posture. 2. When we improved harmful factors that affect farmer's health, conformed the effects on important work efficiency index such as heart rate, electromyovolume, body temperature, and microclimate inside clothing and work loads were decreased by eliminating the hillock and obstacles of ground, decreasing the clothing weight, using proper clothing appliances such as hat and sunglasses, controlling height of working stand and sorter suitably, improving the working postures and methods as using assistant appliances, alloting the working time and sequence effectively and presenting the light gymnastic exercises and rest for fatigue restoration.

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