• Title/Summary/Keyword: Apparent viscosity

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Study on Preparation and Drug Release of Sulconazole Nitrate Gels (질산술코나졸겔의 제조 및 약물방출에 관한 연구)

  • Hyun, Jong-Mok;Kim, Kyung-Kook;Jee, Ung-Kil
    • Journal of Pharmaceutical Investigation
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    • v.26 no.4
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    • pp.263-271
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    • 1996
  • Sulconazole nitrate(SCN), an imidazole derivative which has been effective in the treatment of dermatophytosis, tinea versicolor and candidiasis, was formulated as a gel containing drug, poloxamer 407, ethanol and propylene glycol. The resulting SCN gels were evaluated with respect to their viscosity, drug release rate, skin permeation rate. The apparent viscosity of SCN gel increased in proportion to poloxamer 407, drug and propylene glycol concentration. In case ethanol was added, the apparent viscosity decreased. The drug release rate of SCN gel increased in proportion to temperature and ethanol concentration. But the drug release rate decreased as the concentration of poloxamer 407 increased. The increase of drug concentration induced nonlinear increase of drug release rate. When propylene glycol was added at the level of 10%, the drug release rate increased but from 15% it decreased. The skin permeation rate decreased in high concentration of poloxamer 407. The skin permeation rate of SCN gel containing 15% ethanol increased about twice than that of gel without ethanol. The increase of drug concentration induced nonlinear increase of skin permeation rate. When propylene glycol was added at the level of 10%, the skin permeation rate increased but from 15% it decreased.

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Preparation and Rheological Properties of Chitin and Chitosan -2. Effects of shear rate, temperature, concentration and salts on the viscosity of chitosan solution- (갑각류 외피의 유효이용을 위한 Chitin 및 Chitosan의 제조와 물성학적 특성에 관한 연구 -2. Chitosan 용액의 점도에 미치는 전단속도, 온도, 농도 및 염의 영향-)

  • LEE Keun-Tai;PARK Seong-Min;BAIK Oon-Doo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.28 no.4
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    • pp.397-400
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    • 1995
  • Effects of rheological parameters, such as shear rate, temperature, concerntration, salts on the apparent viscosity of chitosan(deacetylation degree: $84\%$, Mw: 267,000) dissolved in acetate buffer(pH 4.5) were investigated. Rheologiral properties of chitosan solution from cuticle of red snow crab (Chinonecetes japonicus) are as follows. $0.5\%$ chitosan in 0.1M acetate buffer (pH 4.5) solution showed Bingham flow having hysteresis loop. It's flow equation was $\sigma=0.757+19.6_\gamma(r^2=0.99)$. The viscosity of chitosan solution is exponentially increased with its concentration, and showed Arrhenius dependence with respect to the temperature $(10^{\circ}C-40^{\circ}C).$ When various salts were added to chitosan solution, the viscosity decreased as the concentration of counterion increased. But the type ot counterions itself does not have any significant effects on the viscosity.

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Rheological Properties of Dandelion Root Concentrates by Extraction Solvents

  • Lee, Ok-Hwan;Kang, Suk-Nam;Lee, Boo-Yong
    • Food Science and Biotechnology
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    • v.15 no.1
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    • pp.33-38
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    • 2006
  • This study was performed to provide basic rheological data of dandelion root concentrates in order to predict their processing aptitude and usefulness as functional foods material. The hot water and 70% ethanol extracts of dandelion root were concentrated at 5, 20, and 50 Brix, and their static viscosity, dynamic viscosity, and Arrhenius plots were investigated. Almost all hot water concentrates showed the typical flow properties of a pseudoplastic fluid, but evaluation using the power law model indicated that the 70% ethanol concentrates showed a flow behavior close to a Newtonian fluid. The apparent viscosity of hot water and 70% ethanol concentrates decreased with increasing temperature. Yield stresses of hot water and 70% ethanol concentrates by Herschel-Bulkley model application were in the range of 0.026 - 1.368 Pa and 0.022 - 0.238 Pa, respectively. The effect of temperature and concentration on the apparent viscosity was examined by Arrhenius equation. The activation energies of hot water and 70% ethanol concentrates were in the range of $8.762-23.778{\times}10^3\;J/mol{\cdot}kg$ and $3.217-20.384{\times}10^3\;J/mol{\cdot}kg$ with increasing concentration, respectively. Storage (G') and loss (G") moduli were generally increased with increasing frequency. For the 70% ethanol concentrates, G" predominated over G' at all applied frequencies and so they showed the typical flow behavior of a low molecular solution. However, for the hot water concentrates, G' predominated over G" at more than 1.9 rad/sec (cross-over point) and so they showed the typical flow behavior of a macromolecular solution.

Viscosity Properties of Corn, Potato and Sweet Potato Starch according to pH. (옥수수, 감자 및 고구마 전분의 pH에 따른 점도 특성)

  • 최옥자;신말식;조성효
    • Korean Journal of Human Ecology
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    • v.3 no.1
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    • pp.88-99
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    • 2000
  • This study was perfomed to search for how properties of the starch viscosity appear in different qualities, when acetic acid is added. For this study, corn starch which belongs to A-type. Potato starch to B-type. and sweet potato starch to C-type were chosen as an experimental material. which was added to acetic acid controlled as pH 4.0, 4.5, and 5.0 at the time of before and after heating. After that, the viscosity properties of each starch was analyzed using Amylogram and Brookfield viscometer. As a result. the viscosity was shown high in an order of potato. sweet potato, and corn starch. According to addition of acetic acid. tile viscosity appeared to be low. The viscosity differences of before and after heating when the acid is added were shown as follows : Amylogram shows that the lower the pH is. the lower the viscosity is when the acid is added before-heating. In case the acid is added before-heating, gelatinization temperature, consistency and setback was increased. but breakdown decreased. In case the acid is added after-heating, the viscosity goes down at soon as it is added meanwhile consistency and setback was decreased. but breakdown increased. Such properties of the viscosity show a conspicuous variation in an order of potato. sweet Potato. and corn starch. Brookrield viscometer shows that the lower the apparent viscosity is. the lower pH is at the time of before-heating when the acid is added. In case of after-heating, when the acid is added. the apparent viscosity shows a higher inclination than that of before-heating in corn starch and sweet potato starch.

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Fluidity and Setting Properties of Cement Paste by Adding of Fluoro Anhydrite and Fly Ash (불산 무수석고와 플라이 애쉬를 첨가한 시멘트 페이스트의 유동성 및 응결특성)

  • 노재성;김도수;홍성수;임계규;임헌성
    • Journal of the Korean Ceramic Society
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    • v.34 no.12
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    • pp.1261-1267
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    • 1997
  • Four kids of powder admixtures(A, B, C, D) based on anhydrite were manufactured by mixing at a fixed rate of II-anhydrite, fly ash and active silica as an industrial by-product. Fluidity properties of cement paste such as mini-slump, apparent viscosity with elapsed time, as well as setting time of cement pastes of these admixtures substituted up to 11wt% of cement were compared to those of cement paste(SS) substisuted by marketed high-strength powder admixture(S). Among these powder admixtures, the fluidity of cement pastes(PA, PC) substituted by A and C powder admixtures manufactured from II-anhydrite and fly ash had an excellent property than that of cement paste substituted by marketed powder admixture and also a good fluidity-retention effect with elapsed time by adding of superplasticizer. The setting time of cement paste substituted by powder admixtures based on anhydrite slightly retarded than that of cement paste substituted by marketed powder admixture.

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The Effects of Suspension Composition on Defects in Aqueous Tape Casting of Alumina Ceramics

  • Shin, Hyo-Soon
    • Journal of the Korean Ceramic Society
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    • v.41 no.9
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    • pp.647-652
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    • 2004
  • In aqueous tape casting of alumina slurry systems, the relationships between the suspension compositions and the defects of the dried tapes were discussed. The suspensions compositions were controlled with the ratios of the solids, water and organics binder contents. The effects of the thickness of dried tape and kinds of binder system were also examined. In the defect free region, the apparent viscosity showed nearly same value due to the count balancing effect of solid and organic binder content on the apparent viscosity. When water content was constant, increasing solid led to decrease of organic binder content. The defect free region was narrowed with increasing of casting thickness. When linear type acrylic emulsion binders system (D1000 and D 1035) were used, defect free zone formed the belt type in the triangle of solid, water and organic binder content according to the line of constant water contents. However the defect free region was not found in the cross-link type emulsion binder system (D 1050).

Effects of Suspension Composition on Defects in Aqueous Tape Casting of Alumina Ceramics: A Rheological Study

  • Shin, Hyo-Soon
    • Journal of the Korean Ceramic Society
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    • v.42 no.1
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    • pp.1-6
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    • 2005
  • In aqueous alumina tape casting, the effects of altering the composition of the suspensions, the binders and the casting thickness were studied. The rheological behavior of the suspensions and the defects of the dried tapes were examined and the relationships between them are discussed. The changes in the defect regions reported in the previous paper were related with the rheological properties with variations of the binder, the composition and the casting thickness. The shear thinning factor increased with the organic content and the solid content (the decrease of water content). The apparent viscosity increased with the shear thinning factor. The relation between the shear thinning factor and the log apparent viscosity was similar for all binder types. In the relation between the defect free region and the rheological properties, the defect free region became narrower with increasing casting thickness. The defect free region is independent of binder type. Therefore, the thicker tape is more difficult to produce in aqueous alumina tape casting. Knowledge of the rheological properties of the suspensions could help Predict the defect type and the possibility of defect free dried tapes.

STUDY ON TORQUE CONVERTER USING ELECTRO-RHEOLOGICAL FLUID (존가점성 유체를 이용한 동력전달 장치에 관한 연구)

  • 이은준;박명관;주동우
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1995.10a
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    • pp.542-545
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    • 1995
  • This paper provides an investigation of torque converter system using ERF (Electro-Rheological Fluid). The torque converter system using ERP is a new concepting device because we can change an apparent viscosity of ERF by adapting an electric field. The device was designed by using the equations which were proposed by Carlson et al. The devices based on ERF generally assume one two possible forms. One is the parallel plate type in which the device elements are facing circular disks separated by a flat layer of ERF, The other is coaxial cylinder or Couette types in which the ERF file the annular apace between a pair of coaxial cylindrical electrode. The discussion on this study is specifically for coaxial cylinder gemetry and experiment results show that the measured torque was rapidly increased with the increase of the eletric field.

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Fundamental Study on Performance Experiment of ER Clutch (ER클러치의 성능실험에 관한 기초적 연구)

  • 김도태;장성철;염만오;김태형
    • Proceedings of the Korean Society of Machine Tool Engineers Conference
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    • 2001.04a
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    • pp.66-71
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    • 2001
  • In this work, an ER clutch has been constructed and its characteristics have been evaluated by adapting an electro-rheological fluid(ERF) as an operating medium. ER fluids are suspensions which show an abrupt increase in rheological properties under electric fields. An ER clutch system using ER fluid is a new conception device because an apparent viscosity of ER fluid can be changed by apply an electric field. As a first, Bingham properties of ER fluids are experimentally distilled as a function of electric field. We use the disk type ER clutch in which the ER fluid fills the annular space between a pair of coaxial disk electrodes and experiment results show that the measured revolution per minute was increased with the increase of the electric field. The ER fluid used in the present study consists of weight fraction 35% in zeolite suspended silicone oil.

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Micro Plishing using Electorheological fluid (ER유체를 이용한 미세 연마 가공)

  • 김욱배;이성재;박철우;이상조
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2000.11a
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    • pp.850-853
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    • 2000
  • It is well-known that Electro-rheological(ER) fluid is a material(suspension) which shows the dramatic change of rheological properties under an electric field. Using these properties, the concept that variable apparent viscosity of ER fluid could be applicable to the polishing for micro parts was introduced. It was investigated that how it works for polishing and how it affects ER effect when abrasives were mixed with an ER fluid. Therefore a few structures for polishing using ER fluid was suggested and evaluated by means of experiments. In this paper, fundamental mechanism and experimental results are described.

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