• Psychiatry investigation
• /
• v.15 no.11
• /
• pp.1087-1093
• /
• 2018

Objective Posttraumatic stress disorder (PTSD) is distinct from anxiety disorders in its etiology and clinical symptomatology, and was reclassified into trauma- and stressor-related disorders in DSM-5. This study aimed to find neurophysiological correlates differentiating PTSD from anxiety disorders using resting-state quantitative electroencephalography (qEEG). Methods Thirty-six patients with either PTSD or acute stress disorder and 79 patients with anxiety disorder were included in the analysis. qEEG data of absolute and relative powers and patients' medication status on the day of qEEG examination were obtained. Electrodes were grouped into frontal, central, and posterior regions to analyze for regional differences. General linear models were utilized to test for group differences in absolute and relative powers while controlling for medications. Results PTSD patients differed from those with anxiety disorders in overall absolute powers [F(5,327)=2.601, p=0.025]. Specifically, overall absolute delta powers [F(1,331)=4.363, p=0.037], and overall relative gamma powers [F(1,331)=3.965, p=0.047] were increased in PTSD group compared to anxiety disorder group. Post hoc analysis regarding brain regions showed that the increase in absolute delta powers were localized to the posterior region [F(1,107)=4.001, p=0.048]. Additionally, frontal absolute gamma powers [F(1,107)=4.138, p=0.044] were increased in PTSD group compared to anxiety disorder group. Conclusion Our study suggests increased overall absolute delta powers and relative gamma powers as potential markers that could differentiate PTSD from anxiety disorders. Moreover, increased frontal absolute gamma and posterior delta powers might pose as novel markers of PTSD, which may reflect its distinct symptomatology.

• Mood & Emotion
• /
• v.15 no.2
• /
• pp.67-72
• /
• 2017

Objectives : Mindfulness meditation has recently become a major component in mainstream modern cognitive behavioral therapy. The purpose of this study was to examine effects of a mindfulness meditation program on positive resources of outpatients with depressive disorder and anxiety disorder. Methods : Participants were 55 psychiatric clinic outpatients. Participants received eight weekly sessions in a mindfulness meditation training program, that was approximately 90 minutes each. Measures included the Positive Resources Test (POREST), Acceptance and Action Questionnaire-16 (AAQ-16), Life Satisfaction Expectancy Scales (LSES), and Subjective Happiness Scale (SHS). Variables were measured at two time points : pre- and post-implementation (eight weeks later). Results : Paired t-test results of participants before and after the mindfulness meditation program revealed statistically significant improvement in positive resources (t=-5.847, p<.001), acceptance (t=-4.090, p<.001), life satisfaction expectancy (t=-3.892, p<.001), but not in subjective happiness. Conclusion : Results suggest mindfulness meditation may be effective to enhance positive resources, acceptance, and life satisfaction in outpatients with depressive disorder and anxiety disorder. Mindfulness meditation may be a factor in improving psychological well-being and positive psychological features in outpatients with depressive disorder and anxiety disorder.

• CELLMED
• /
• v.6 no.3
• /
• pp.19.1-19.3
• /
• 2016

Jindo Ssitgimgut has been known as a funeral ritual for a long time in Korea. However, there is no study for music therapy on anxiety disorder. The aims of this study were to argue that Oral sound Daseureum of Jindo Ssitgimgut may have meaningful effect on anxiety disorder. Jindo Ssitgimgut is literally a cleansing soul. Jindo Ssitgimgut is designated as the Intangible Cultural Property No. 2 by the Korean government. Jindo Ssitgimgut is transmitted from generation to generation, not the descent of God. So, the accent is on art and one's sincere sympathy. So, with careful listening Youtube, this music Daseureum exhibits an exquisite balance between the human voice and the sounds do the instruments. The author think a good combination of his voice, Jing (Korean gong), and Ajaeng (Korean cello) can help with anxiety disorder.

• Anxiety and mood
• /
• v.4 no.2
• /
• pp.91-98
• /
• 2008

Depression and anxiety disorders are common psychiatric illnesses whose etiology remains partially understood. The etiology of depression and anxiety disorders is multi-factorial, and abnormalities in neurotransmitter, neuroendocrine system, and brain activation have been implicated in those conditions. However, the pathophysiology of depression and anxiety disorder is certainly not well understood, and some patients with depression or anxiety disorders do not respond to antidepressant therapy. Recently, immunological factors such as cytokines are known to be closely related to central nervous system as well as depression and anxiety disorders. This review highlights recent progress in understanding the function of cytokines in depression and anxiety disorders.

• The Journal of Pediatrics of Korean Medicine
• /
• v.19 no.2
• /
• pp.153-163
• /
• 2005

Objectives : The purpose of this study is to find out whether Ondam-tang has any effects on adolescence with anxiety disorder Methods : The subject is in regard to 1 case with anxiety disorder who adnutted at ${\bigcirc}{\bigcirc}$ Oriental Medical hospital from 29th of June to 7th of July. The herbal therapy (Acupuncture, Moxa, Aroma therapy) is applied. Results : After treatment, in a week, most of symptoms (insomnia, anxiety, the problem of verbal expression, chest discomfort, palpitation, anorexia, digestion, headache, dizziness, thirst, eye discomfort, etc) were subsided. Conclusion : Anxiety disorder is similar to Simdamhugup in Oriental medicine. Ondam-tang has been used for long time for treatment on Simdamhugup. Ondam-tang is effective medication for adolescence with anxiety disorder, but more studies about adolescence and Oriental approach of psychiatries are needed.

• Korean Journal of Biological Psychiatry
• /
• v.16 no.1
• /
• pp.46-52
• /
• 2009

Objectives : The goal of this study was to compare the clinical characteristics of panic disorder respiratory subtype(PD-R) and non-respiratory subtype(PD-NR). Methods : 84 patients with panic disorder were enrolled and divided into 2 groups, 29 PD-R and 55 PD-NR. Diagnosis of panic disorder was evaluated using Diagnostic and Statistical Manual of Mental Disorders $4^{th}$ edition and Mini International Neuropsychiatric Interview. They were also measured with Hamilton Rating Scale for Anxiety(HAM-A), Hamilton Rating Scale for Depression(HAM-D), and Panic Disorder Severity Scale (PDSS). Results : PD-R group showed significantly higher scores in PDSS than those of PD-NR group(p=.027). After controlling for the severity of panic disorder and gender, PD-R group showed higher HAM-D and somatic anxiety subscale of HAM-A than those of PD-NR group. Furthermore, results of logistic regression analysis suggested that the somatic anxiety was a possible risk factor of PD-R(OR=1.404,p=0.009). Conclusion : These results suggest that somatic anxiety and depressive symptom would be important clinical characteristics of PD-R.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.21 no.3
• /
• pp.147-152
• /
• 2010

Objectives : The purpose of this study was to investigate the deficits in executive function in children with ADHD and anxiety disorder, and further, to characterize executive function deficits among the two groups. Methods : Subjects consisted of 60 children between the ages of 5 and 14 (16 Normal, 24 ADHD, 20 Anxiety Disorder). Neuropsychological tests (KEDI-WISC, CCTT, STROOP, WCST, ROCF) for assessing cognitive and executive function were individually administered to all subjects. Results : There were no significant differences in FSIQ or PIQ among the three groups. However, the ADHD group tended to score lower on the VIQ and subtest of similarity, vocabulary, and digit span tests. The three groups did not significantly differ with respect to CCTT test results. On the STROOP test, the ADHD group showed poor performance on the word, color, and color-word subtests. The three groups did not exhibit significant differences in WCST test results ; however, the anxiety group performed poorly belonging to below 25 percentile rank on perseverative response. On the ROCF test, the ADHD group performed poorly with respect to their organization score and in particular, regarding copy and immediate recall. The anxiety group also performed poorly with regard to organization ; however, this was limited only to immediate recall. Conclusion : Children with ADHD displayed poor inhibition and organizational abilities compared to children with anxiety and normal controls. Further, children with anxiety disorder exhibited low cognitive flexibility and voluntary problem-solving abilities compared to ADHD children and normal controls. Based on these results, we suggest that the characteristics of executive dysfunction in ADHD and anxiety disorder in children are different.

• Korean Journal of Biological Psychiatry
• /
• v.22 no.4
• /
• pp.216-222
• /
• 2015

Objectives The principal aim of the present study was to investigate the characteristic depressive symptoms in patients with social anxiety disorder (SAD) and panic disorder in comparison to patients with depressive disorder. Methods This study included 132 patients with SAD, 128 panic disorder and 64 depressive disorder (major depressive disorder, dysthymia etc.) patients without comorbid psychiatric disorders. The Beck Depressive Inventory (BDI) is used to measure depressive symptoms. We divided BDI into three categories originally described by Shafer AB, including negative attitude toward self, performance impairment, and somatic symptoms. We compared the depressive symptoms of SAD, panic disorder and depressive disorder by using ANOVA. Results Negative attitude toward self was noticeable in SAD (SAD $0.54{\pm}0.23$, panic disorder $0.41{\pm}0.17$, depressive disorder $0.46{\pm}0.11$, p < 0.001). Performance impairment and somatic symptoms were remarkable in panic disorder than in SAD and depressive disorder (performance impairment : SAD $0.39{\pm}0.21$, panic disorder $0.44{\pm}0.14$, depressive disorder $0.40{\pm}0.09$, p = 0.009 ; somatic symptoms : SAD $0.07{\pm}0.10$, panic disorder $0.15{\pm}0.12$, depressive disorder $0.14{\pm}0.08$, p < 0.001). Conclusions The results facilitate an approach to optimal treatment for patients with comorbidity of anxiety disorder and depression.

• CELLMED
• /
• v.6 no.4
• /
• pp.27.1-27.4
• /
• 2016

Anxiety is a common clinical presentation. Primary anxiety poses a significant problem in its management. Many among the current treatment options of anxiety are habit forming causing significant withdrawal symptoms. There are dose dependent responses often associated with drug adversities. Day time sedation is an undesired effect of many drugs used for anxiety management limiting its usage. Ayurveda recommends a bio- physical procedure to manage anxiety. Shirodhara, a dripping procedure is utilized as a front line therapy for anxiety in Ayurveda. Seeing the limitations of conventional biomedical management of anxiety requiring an improvement upon the existing protocols of managements, and also seeing the use of shirodhara for anxiety management in ayurvedic clinics, a pragmatic study to evaluate the effect of shirodhara in generalized anxiety disorder was done. This was a pragmatic study consisting of shirodhara with ksheer bala oil as an intervention upon generalized anxiety disorder patients. The study was conducted upon 13 patients and observations were done for six weeks. The responses observed through the changes in Hamilton Anxiety Scale were evaluated using paired t test to observe the pre-post significance.

• The Journal of Churna Manual Medicine for Spine and Nerves
• /
• v.1 no.2
• /
• pp.21-29
• /
• 2006

Objective: The aim of this study is to investigate whether patients with temporomandibular disorder have more anxiety than normal people. Methods: Patients group(n=50) with TMD and normal group(n=30) without TMD and other disease completed STAl(State-Trait Anxiety Inventory), and there was comparison of mean scores between patients and normal groups. Results: The mean of total STAl scores of patients group was $91.32{\pm}20.32$, whereas that of normal group was $81.27{\pm}12.97(p<0.01)$. The mean of state-anxiety scores of patients group was $45.68{\pm}11.30$, whereas that of normal group was $40.70{\pm}7.28(p<0.05)$. The mean of trait-anxiety scores of patients group was $45.64{\pm}10.02$, whereas that of normal group was $40.57{\pm}7.22(p<0.05)$. There was a tendency that patients with TMD had more anxiety. So, doctors had better give attention to patients' anxiety when they treat the patients with TMD.