• 한국식품영양과학회지
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• 제31권3호
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• pp.506-510
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• 2002

본 연구는 불포화 인지질인 DLPC liposome에 도라지(Platycodon grandiflorum A. DC, PG)의 용매별 분획물 일정 량을 가하고, 산화제 benzoyl peroxide를 가한 후 시료의 항산화 작용을 비교 분석하였다. 도라지 용매별 추출물 중 ethylether 분획물인 PGMEE와 ethylacetate 분획물인 PGMEA는 $\alpha$-tocopherol의 경우 보다 훨씬 그 산화지수가 낮아두 분획물에 의한 강한 항산화력을 측정할 수 있었으며, 잘알려진 강력한 항산화제인 BHT(butylated hydroxytoluence)의 경우와 비슷한 항산화 효과를 나타내었다. 한편 PGMEE 분획층에 비타민 C를 일정량을 첨가함으로서 상호 보강 작용에 의한 항산화 상승효과를 본 결과, Vit C를 첨가하지 않았을 때보다 산화지수가 횔씬 낮아졌다. BHT 함유의 DLPC liposome의 경우도 Vit C에 의한 비슷한 추과를 나타내었다. 이상의 결과에 의하여 도라지의 PGMEE 분획층에는 BHT와 비슷한 강한 항산화 효과를 가진 물질의 존재가 분명하다고 사료되며 비타민 C 첨가로 인한 항산화 상승 효과도 본 연구결과에 의해 뚜렷이 알 수 있었다. 이와 같은 연구에 의해 여러 질병들의 원인이 될 뿐만 아니라 세포막 손상을 일으키는 활성 산소 또는 유리기의 생성억제 등 균형된 식생활을 통한 식품 섭취의 중요성이 매우크다고 인식되며 특히 식품으로서 애용되고 있는 도라지의 인지질 세포막에 미치는 항산화 효과가 식품으로서 약이 되는 기전 규명에 기초자료가될 것을 바라는 바이다.

• 동아시아식생활학회지
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• 제21권5호
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• pp.637-648
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• 2011

This study was designed to investigate the relationship between the nutrient intakes, antioxidants, and inflammatory markers of overweight and obese adults (46 females and 16 males) in Yeongdong area. The study was conducted through questionnaires, anthropometric checkups, 2-day 24 hr recalls and blood biomarker analyses. Body fat was significantly higher in women compared to men. Diastolic blood pressure (DBP) and systolic blood pressure (SBP) were significantly higher in men compared to women. There were no significant differences in height, weight, body mass index, and waist size among the two groups. The intake of nutrients was significantly higher in men compared to women. Ferric reducing ability plasma (FRAP) was significantly higher in men compared to women. Body fat was positively associated with blood IL-6 and IL-8 levels. DBP was positively associated with FRAP. The intake of protein was negatively associated with IL-6 levels. The intake of carbohydrates was negatively associated with total antioxidant capacity (TAC). Prostaglandin E2 (PGE2) levels were negatively associated with TAC. These results suggest that antioxidant and inflammatory markers may be related to the body fat percentage and dietary intake in overweight and obese adults.

• 한국포장학회지
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• 제26권1호
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• pp.19-23
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• 2020

Al-laminated packaging film incorporating ascorbic acid or tocopherol at inner food contact layer was tested in the potential to improve antioxidative preservation of powdered infant formula under CO₂-enriched atmosphere. Product of 200 g was packaged with the packaging film containing 0.3% antioxidant in sealant layer of low density polyethylene and stored at 30℃ for 286 days with periodic measurement of package atmosphere and product's quality attributes. The CO₂-flushed package resulted in shrinkage of tight contact between the product and the film not allowing gas sampling of package atmosphere after 140 days. Package of tocopherol-incorporated film allowed some ingress of oxygen after 112 days presumably due to its weakening of heat-seal area. The increased oxygen concentration in the tocopherol-added film package led to the concomitant increase of peroxide value, an index of lipid oxidation. On the other hand, packaging of ascorbic acid-added film pouch could suppress lipid oxidation marginally in consistent manner compared to control package without any antioxidant.

• 대한수의학회지
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• 제53권4호
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• pp.231-237
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• 2013

This study aimed to assess the attraction effect against Lycorma delicatula and antioxidant activity of hexane, chloroform, butanol and water fraction obtained from Ailanthus altissima methanol extract. The attraction effect of chloroform fraction showed the highest activity (47%) as compared to that of other fractions. In the DPPH radical scavenging activity, methanol and butanol fraction showed higher antioxidant activity than other solvent fractions. From the above results, the potential chloroform fraction was further performed by local irritation test in New Zealand white rabbits. In eye irritation test, chloroform fraction showed moderate irritant at high concentration 0.5 g/site/mL, but there was no eye irritation at low concentration (0.05 g/site/mL). In accordance with the Draize evaluation of skin irritation, the primary irritation index was calculated to 3.3 and 0.68 at high (0.5 g/site/mL) and low concentration (0.05 g/site/mL) causing moderate and mild irritation, respectively. On the basis of this study, Ailanthus altissima chloroform fraction could be safely considered to be a candidate of attractant against Lycorma delicatula.

• Nutrition Research and Practice
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• 제4권4호
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• pp.303-310
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• 2010

Consumption of vegetables and fruits is associated with a reduced risk of stroke, but it is unclear whether their protective effects are due to antioxidant vitamins or folate and metabolically related B vitamins. The purpose of the study was to test the hypothesis that intake of fruits and vegetables, which are major sources of antioxidant and vitamin B complex vitamins, reduces the risk of stroke. Cases consisted of patients diagnosed with first event of stroke (n = 69). Controls (n = 69) were age-, sex-, and body mass index-matched to cases. Multivariable-adjusted regression analysis showed that subjects who ate four to six servings of vegetable per day had a 32% reduction in the risk of stroke, and those with more than six servings per day had a reduction of 69% after adjusting for age, sex, BMI, and family history of stroke. Intakes of total fat, plant fat, calcium, potassium, vitamin $B_1$, vitamin $B_2$, vitamin $B_6$, niacin, and folate were significantly and negatively associated with the risk of stroke. Although the trend was not significant, stroke risk was reduced in the second quartile (1.21-2.66 servings per week) of fish intake. However, intake of fruits (average daily intake of 1.0 serving) and antioxidant vitamins such as carotene, vitamin C, and vitamin E was not associated with the risk of stroke. In conclusion, our observational study suggests that intake of fat and vegetables, rich sources of vitamin B complex, calcium, and potassium may protect against stroke.

• Journal of Nutrition and Health
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• 제33권4호
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• pp.454-463
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• 2000

The purpose of this study was to assess the biochemical nutritional status of the long-lived elderly. The subjects of the study were 148 elderly people of age over 85 years living in Kyungpook Sung-Ju area who have no problem in daily living. The anthropometric measurement and biochemical assessment of the blood sample were carried out. The subject group for this study was composed of 25.9% males and 74.1% females, the average age being 87 years old. The mean Body Mass Index(BMI) of the male and female subjects were 20.7 and 21.2 respectively. The average body fat amounts of the male and female were 21.4% and 29.8% respectively, and the average waist/hip ratios were 0.9 and 0.7 respectively. The mean levels of the total blood protein and albumin of the subjects were in the normal ranges. The mean levels of serum cholesterol and triglyceride were 167.9mg /dL and 123.9mg/dL respectively. The mean levels of the subjects below normal range of hemoglobin were 63.5%. Serum levels of antioxidant nutrients were very poor. The mean levels of serum lipid peroxidation products were 3.3nmol/mL. BMI and WHR were positively correlated with the serum cholesterol levels. The resuts showed that the long-lived elderly had good nutritional status except for antioxidant nutrients status. In addition antioxidant supplement for long-lived elderly may be effective to maintain healthy life in later years.

• Journal of Acupuncture Research
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• 제25권1호
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• pp.107-120
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• 2008

Objectives : This study investigated the antioxidant effect of electro-acupuncture at $KI_6$ on rats treated with 2,2'-azobis(2-amidinopropane) dihydrochloride(AAPH). Methods : After electro-acupuncture at $KI_6$ on 48 rats that were given AAPH(50mg/kg) every day, the author observed several changes in weight, liver index, albumin, total bilirubin, LDL-cholesterol, LDH, glucose, GOT, GPT, SOD and catalase activity, and glutathione, NO, and MDA concentrations. Results : 1. In the $KI_6-EA$ group, the albumin level increased and LDL-cholesterol decreased compared with the control and holder groups. 2. In the $KI_6-EA$ group, SOD activity increased compared with the holder group, glutathione concentration increased compared with the control and holder groups, and catalase activity increased compared with the control group. 3. In the $KI_6-EA$ group, NO concentration decreased compared with the control and holder groups. Conclusions : This case shows that electro-acupuncture at $KI_6$ plays a significant antioxidant role by elevating defenses against cell toxicity caused by oxidative stress and suppressing oxidative injury.

• Preventive Nutrition and Food Science
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• 제21권2호
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• pp.79-84
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• 2016

Apium graveolens Linn. (Apiaceae) is an indigenous plant of the North and South Americas, Southern Europe, and Asia and has been widely used as a food or a traditional medicine for treatment of inflammation and arthritis. The purpose of this study was to investigate the antioxidant effects of a methanolic extract of A. graveolens (AGE) against liver oxidative stress in an adjuvant-induced arthritic rat model. The AGE (250, 500, and 1,000 mg/kg) was given orally for 24 consecutive days after induction by injecting complete Freund's adjuvant. Liver and spleen weights were recorded. The superoxide anion level, total peroxide (TP), glutathione peroxidase (GPx) activity, superoxide dismutase (SOD) activity, total antioxidant status, and oxidative stress index (OSI) were also measured. AGE treatment significantly decreased the levels of the superoxide anion, TP, and OSI whereas the GPx and SOD activities significantly increased in the liver of the arthritic rats. These results indicated that AGE showed an ameliorative effect against liver oxidative stress in adjuvant-induced arthritic rats by reducing the generation of liver free radicals and increasing the liver antioxidant enzyme activity.

• 한국식품영양학회지
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• 제31권2호
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• pp.258-263
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• 2018

To assess a potential possibility of Deoduck as functional food resources, this study was performed to determine the changes in chemical components and antioxidant activities on Deoduck with various aging conditions; aging temperatures were 60, 70, and $80^{\circ}C$, and aging periods were 5, 10, 15, 30, and 50 days. We determined pH, total acidity, browning index, 5-hydroxymethyl-furfural, total phenolic contents, DPPH and ABTS radical scavenging activities of aged Deoduck. Total acidity of aged samples increased during aging treatment, at higher temperature and longer time. The pH value of aged Deoduck ranged from 4.97 to 3.76. Aged Deoduck at $60^{\circ}C$ decreased slowly than 70 and $80^{\circ}C$, and these results were similar in total acidity. 5-HMF and total phenolic contents increased when increased aging temperature and periods. The DPPH and ABTS radical scavenging activities of Deoduck were ranged from 0.374 to 1.560 mg TEAC eq/g and from 0.302 to 1.745 mg trolox eq/g, respectively.

• 폴리머
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• 제26권4호
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• pp.452-461
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• 2002

본 연구에서는 폴리아미드 6 (PA 6)을 70~$160^{\circ}C$에서 장시간 사용하였을 때 산화방지제의 사용유무 및 농도에 따른 열 안정성을 조사하였다. 70~$160^{\circ}C$의 온도범위내의 열 산화반응 시 모든 시료는 100시간 내에 황변 현상이 일어났다. 기계적 물성, 황변 지수, 점도측정으로 가장 적정한 산화방지제의 농도를 조사하였다. 일, 이차 산화방지제의 조성변화에 의한 산화방지효과는 미미하였다. 황변 현상의 분석은 NMR, IR, 그리고 element analysis (EA)를 사용하였다. $^{13}C$ NMR에 의해 서로 다른 카르보닐기의 존재를 확인하였으며, 산소의 소모량 측정은 EA를 사용하였다. Arrhenius식을 이용하여 산화방지제를 첨가한 시료와 그렇지 않은 시료의 lifetime을 예측하였다.