• Title/Summary/Keyword: Antimicrobial acitivity

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Antimicrobial Activity against Respiratory Bacteria by Asparagus Cochinchinensis Extracts and its Antioxidant Capacity (천문동 추출물의 호흡기 세균에 대한 항균활성 및 항산화)

  • Jung, Min-Gi;Kim, Su-In;Jeong, Hae-Jin;Lee, Chung-Yeol;Son, Hong-Joo;Hwang, Dae-Youn;Lee, Hee-sup;Kim, Dong-Seob
    • Microbiology and Biotechnology Letters
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    • v.43 no.4
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    • pp.367-372
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    • 2015
  • This study was aimed at determining the antioxidant and antimicrobial effects of solvent extracts from Asparagus cochinchinensis. The Asparagus cochinchinensis was extracted with water, methanol, ethanol, n-hexane, dichloromethane, ethyl acetate, and ether. The antimicrobial activity of these extracts was determined by modified well diffusion methods against 4 species of respiratory disease bacteria (Staphylococcus aureus, Escherichia coli, Staphylococcus epidermidis, and Pseudomonas aeruginosa). In addition, the amount of total polyphenol and flavonoid content, and antioxidant activity was evaluated. Ethyl acetate extract of A. cochinchinensis exhibited higher antimicrobial activity against tested microorganisms than water, methanol, ethanol, n-hexane, dichloromethane, and ether extracts. For antioxidant activity, the ethyl acetate extract of A. cochinchinensis exhibited a notable effect on the scavenging of superoxide against DPPH ($IC_{50}=3.81mg/ml$). Finally, the total polyphenol and flavonoid contents were $14{\pm}0.7mg/g$, and $0.50{\pm}0.13mg/g$, respectively. These results can be regarded as basic research into A. cochinchinensis for the prevention of respiratory diseases. The results indicate that A. cochinchinensis may be utilized as a nutraceutical for respiratory diseases when the physiologically active substances of A. cochinchinensis are increased by further study.

Antimicrobial Activities of Scutellaria baicalensis Georgi Against Various Pathogens and Spoilage Bacteria Isolated from Tofu (두부 부패 미생물과 병원성 미생물에 대한 황금의 항균효과)

  • Woo, In-Taeck;Park, Kyung-Nam;Lee, Shin-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.4
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    • pp.470-475
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    • 2007
  • Antibacterial activities of Scutellaria baicalensis Georgi (SBG) extract were examined against spoilage bacteria isolated from commercial tofu and various pathogens such as Listeria monocytogenes ATCC 19115, Pseudomonas fluorescens ATCC 21541. Staphylococcus aureus ATCC 29737, Salmonella Typhimurium ATCC 11806, Vibrio parahaemolyticus ATCC 17802, and Aeromonas hydrophila KCTC 2358. Four kinds of spore forming organisms were isolated from commercial tofu and identified as Bacillus sp. KN-4, Bacillus sp. KN-6, Bacillus sp. KN-10 and Bacillus sp. KN-20 using API CHB kit. The SBG extract showed high antibacterial activities and significantly inhibited the growth of the isolated spoilage bacteria and pathogens. The inhibitory effects against the organisms increased as the concentration of the SBG extract increased. The antimicrobial activities of the SBG extract were maintained markedly after heat treatments $(80^{\circ}C/30\;min,\;100^{\circ}C/30\;min\;and\;121^{\circ}C/15min)$. The minimum inhibitory concentrations (MIC) of the SBG extract against the organisms ranged from 1,000 ppm to 5,000 ppm.