• 한국버섯학회지
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• 제21권4호
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• pp.195-199
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• 2023

The fungus Alternaria alternata, responsible for causing brown to black spotting on numerous fruits and vegetables globally, was identified in 2022 as the causative pathogen of brown spot disease in potatoes in Korea. In pursuing potential inhibitors against A. alternata growth, we evaluated 15 mushroom culture filtrates: eight from Trametes spp. and seven from Polyporus spp., known for their antibacterial and anticancer properties. Antifungal activity was assessed by exposing each filtrate to A. alternata on a paper disc. Four filtrates displayed inhibitory action against the fungus, albeit with mild effects. Our findings highlight the potential of Trametes and Polyporus fungi as emerging antifungal candidates, offering promise in preventing potato brown spots.

• Journal of Plant Biotechnology
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• 제50권
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• pp.27-33
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• 2023

Zizyphus jujube is a plant in the buckthorn family (Rhamnaceae) that has been the subject of research into antibacterial, antifungal and anti-inflammatory properties of its fruit and seed. However, few studies have investigated its leaves. In this study, the anti-inflammatory activity of ZJL (an extract of Z. jujube leaf) was evaluated to verify its potential as an anti-inflammatory agent and SARS-CoV-2 medicine, using nitric oxide (NO) assay, RT-PCR, SDSPAGE, Western blotting, and UHPLC/TOFHRMS analysis. We found that ZJL suppresed pro-inflammatory mediators such as NO, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and tumor necrosis factor α (TNF-α) in lipopolysaccharide (LPS)-induced RAW264.7 cells. ZJL acted by inhibiting NF-KB and MAPK signaling pathway activity. We also confirmed that ZJL contains a phenol compound and flavonoids with anti-inflammatory activity such as trehalose, maleate, epigallocatechin, hyperoside, catechin, 3-O-coumaroylquinic acid, rhoifolin, gossypin, kaempferol 3-neohesperidoside, rutin, myricitrin, guaiaverin, quercitrin, quercetin, ursolic acid, and pheophorbide a. These findings suggest that ZJL may have great potential for the development of anti-inflammatory drugs and vaccines via inhibition of NF-κB and MAPK signaling in LPS-induced RAW264.7 cells.

• 한국식품저장유통학회지
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• 제16권6호
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• pp.924-928
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• 2009

녹차에 관한 최근까지의 연구결과에서, 녹차는 생리활성의 촉진작용뿐아니라 항암, 항산화, 고혈압 억제효과, 체중 조절 등 다방면의 약리효과를 보이는 것으로 보고되고 있다. 아울러, 녹차의 항균 및 항진균 작용에 관한 연구결과도 발표되고 있으며, 본 연구팀에 의해서도 녹차추출물의 항균작용을 확인한 바 있어, 본 연구에서는 탁월한 항균작용을 소유하고 있는 녹차분획물질을 분리하여 그 분자구조를 동정하는데 목적이 있다. 따라서, 녹차추출물에서 탁월한 항균력을 가지는 항균활성물질을 HPLC 분리방법 및 NMR 분석법으로 분리 동정한 결과, 각각 (-)-epicatechin gallate 및 (-)-epigallocatechin gallate로 확인되었다.

• The Korean Journal of Physiology and Pharmacology
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• 제19권2호
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• pp.151-158
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• 2015

Recently, Cynanchi wilfordii Radix has gained wide use in Asian countries as a functional food effective for relieving fatigue, osteoporosis, and constipation, particularly in menopausal disorders. However, its anti-inflammatory and anti-microbial activities have not been explored in detail to date. The anti-inflammatory, antioxidant, and anti-bacterial properties of the Cynanchi wilfordii Radix extracts obtained with water, methanol, ethanol, and acetone were compared. All 4 polyphenol-containing extracts exhibited anti-inflammatory and antioxidant effects. The ethanol extract was found to elicit the most potent reduction of nitric oxide (NO), prostaglandin $E_2$ ($PGE_2$), and cytokine (IL-$1{\beta}$, IL-6, IL-10, and TNF-${\alpha}$) levels, as well as inhibit the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in a concentration-dependent manner. The evaluation of antioxidant activity also revealed the ethanol extract to have the highest free radical scavenging activity, measured as $85.3{\pm}0.4%$, which is equivalent to 99.9% of the activity of ${\alpha}$ -tocopherol. In the assessment of anti-bacterial activity, only ethanol extract was found to inhibit the growth of the Bacillus species Bacillus cereus and Bacillus anthracis. These results show that polyphenols of Cynanchi wilfordii Radix have anti-inflammatory, antioxidant, and anti-bacterial properties that can be exploited and further improved for use as a supplementary functional food, in cosmetics, and for pharmaceutical purposes.

• 펄프종이기술
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• 제44권3호
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• pp.49-55
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• 2012

Even though corrugated boards are the most common packaging materials for agricultural products, conventional corrugated boards are not able to maintain the freshness of agricultural products. In order to overcome the limitations of conventional corrugated boards, a new hybrid corrugated board-composed of linerboard, a corrugating medium, and non-woven fabric-was designed to possess antibacterial, high porous and shock-absorbing properties. In this study, we compared the physical properties of non-woven fabric to those of the base papers of conventional corrugated boards and developed a new adhesive system as a first step toward manufacturing the hybrid corrugated board. We found that the non-woven fabric, which had relatively high elongation, was applicable in the corrugated board process, and that the manufacturing conditions must be controlled in order to prevent the break of the non-woven fabric. The mixture of starch and styrene-butadiene (SB) latex showed high adhesive strength, but the addition level of SB latex should not exceed 30% in starch solution.

• 한국의류산업학회지
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• 제22권1호
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• pp.66-75
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• 2020

This study helps develop cool-touch functional dance sportswear. We suggest a draft design for dance sportswear that chooses appropriate cool-touch functional materials based on an investigation of the changes of body surface temperature before and after exercise, the physical properties of cool-touch materials on the market, and the preference for cooling tools. The results are as follows. First, cool-touch functional sportswear products on the market utilize materials such as PCM, Delta fabric, high gauge fabric, and ice chips as well as incorporate functions such as UV block and eyelets for enhanced breathability. Polyester and polyurethane fibers are mainly used for cool-touch functional sportswear. Second, the neck area showed the highest surface temperatures (32.7℃ and 32.1℃) before and after exercise. Body surface temperatures measured after exercise were also lower than temperatures measured before exercise when wearing dance sportswear. Third, as for the physical properties of cool-touch materials, material 1 showed amaximum drying speed (130 min), material 3 the best moisture absorption speed (122 × 132 min), and material 4 the best thermal conductivity (0.013 7 w/m·K). Fourth, a draft design for a cool-touch functional dance sportswear was suggested, including a neckband made of removable soft PVC material on the neck area and applying material 4 in F1, B4, S2 and lower arm areas and material 1 in the armpit area. Deodorant tape was also attached to the armpit area for added comfort and antibacterial deodorant effect.

• 한국의류학회지
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• 제28권6호
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• pp.795-806
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• 2004

Unripe indigenous persimmons which contain rich tannins have been used as natural dye materials traditionally and have been using continuously for dyed clothes named Gal-ot in Jeju. Those persimmons were cheap and easy to use as dyes because of inedible and widely cultured in Korea. Persimmon juice dyes not only make fabrics brown-color but also give functional and hygienic properities such as stiffness, air ventilation of clothes, antibacterial activity, protectivity against ultraviolet light. However there are several serious problems which are ristriction of dyeing periods, longtime irradiation, uneven color and low color fastness etc. in persimmon juice dyeing. This study purpose to improve dye effect and method in order to enlarge useability of persimmon juice dyeing. Cotton fabrics were pad-dyed to 100% pick-up using padding machine after dipping in persimmon juice extracted from unripe persimmons indigenous from Jeju. It was possible and available to control pick-up rate. The color of dyed cotton fabrics by padding method was more even and repeatable than which by traditional hand method. Persimmon juice concentrations were 4 types of 10, 25, 50 and 100％. The more concentration increased, the more color deepened. UV Irradiation instead of sunlight was applied to color developing. Irradiation times were shortened till 1∼8 hrs. Same color values could be taken without water wetting which were required in sunlight irradiation. Tensile strengths of cotton fabrics pad-dyed with low concentration of persimmon juice decreased but recovered at high concentrations. Elongations(％) of cotton fabrics pad-dyed with persimmon juice were increased 1％ more than undyed cotton in sunlight irradiation. Drape stiffness increased upto double times as much as.

• 접착 및 계면
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• 제12권4호
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• pp.125-132
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• 2011

최근 실내공간에서의 안전성을 확보하기 위해 유해물질의 방출이 없는 천연재료의 사용이 요구됨에 따라 음식재료인 마늘을 이용한 도배용 천연마늘접착제의 제조와 그 성능에 관하여 검토하였다. 마늘을 이용한 천연접착제는 생마늘을 물로 추출하여 탄수화물과 단백질을 분리 및 농축하는 방법에 의해 제조가 가능하였다. 제조한 천연마늘접착제의 접착성능은 불휘발분의 양에 의해 크게 영향 받았으며, 최적의 불휘발분은 60% 전후였다. 제조한 천연마늘 수지의 특성은 불휘발분 62%, 밀도 $1.3g/cm^3$, 점도 2,789 mPa s, pH 6.6이었다. 또한, 마늘 접착제의 접착성능은 KS의 기준을 크게 상회하였으며, 방부제의 첨가 없이도 마늘이 가지고 있는 항균성을 유지하고 있었으며, 특히 휘발성유기화합물과 폼알데하이드의 방산이 거의 없는 매우 안전한 천연접착제로서의 이용이 가능할 것으로 기대된다.

• Mycobiology
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• 제43권4호
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• pp.415-422
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• 2015

The study aimed to evaluate the probiotic properties, antioxidant activity and fermentative capacity of Acremonium charticola and Rhizopus oryzae isolated from the Indonesian fermented dried cassava, with particular application on poultry. A. charticola inhibited the growth of Escherichia coli and Aspergillus flavus. A. charticola and R. oryzae grew in potato dextrose agar (PDA) adjusted to pH 3 and 8 or in PDA supplemented with bile salt up to 0.8%. After soaking for 8 hr, the survival rate of A. charticola in the simulated gastric juice (pH 2) and bile solutions (2% bile salt) was lower than that of R. oryzae. A. charticola and R. oryzae exhibited strong antioxidant activities. Compared to unfermented cassava pulp (control), the fibre content of cassava pulp tended to be lower after fermentation with A. charticola for 14 days. The populations of A. charticola and R. oryzae were significantly higher in fermented cassava pulp than in unfermented one. Coliform was higher in cassava pulp fermented with R. oryzae or A. charticola + R. oryzae compared to control after 7 days of fermentation, however, the bacteria were not different between A. charticola-fermented cassava pulp and control. Lactic acid bacteria (LAB) were higher in A. charticola- and R. oryzae-fermented cassava pulp than those in control, however, no difference of LAB was observed between A. charticola + R. oryzae-fermented cassava pulp and control. In conclusion, A. charticola exhibited antibacterial, antifungal and antioxidant activity, gastrointestinal persistence and fermentative capacity that may be beneficial for poultry industry.

• Restorative Dentistry and Endodontics
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• 제40권3호
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• pp.195-201
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• 2015

Objectives: The use of chitosan nanoparticles (CNPs) in endodontics is of interest due to their antibiofilm properties. This study was to investigate the ability of bioactive CNPs to remove the smear layer and inhibit bacterial recolonization on dentin. Materials and Methods: One hundred bovine dentin sections were divided into five groups (n = 20 per group) according to the treatment. The irrigating solutions used were 2.5% sodium hypochlorite (NaOCl) for 20 min, 17% ethylenediaminetetraacetic acid (EDTA) for 3 min and 1.29 mg/mL CNPs for 3 min. The samples were irrigated with either distilled water (control), NaOCl, NaOCl-EDTA, NaOCl-EDTA-CNPs or NaOCl-CNPs. After the treatment, half of the samples (n = 50) were used to assess the chelating effect of the solutions using portable scanning electronic microscopy, while the other half (n = 50) were infected intra-orally to examine the post-treatment bacterial biofilm forming capacity. The biovolume and cellular viability of the biofilms were analysed under confocal laser scanning microscopy. The Kappa test was performed for examiner calibration, and the non-parametric Kruskal-Wallis and Dunn tests (p < 0.05) were used for comparisons among the groups. Results: The smear layer was significantly reduced in all of the groups except the control and NaOCl groups (p < 0.05). The CNPs-treated samples were able to resist biofilm formation significantly better than other treatment groups (p < 0.05). Conclusions: CNPs could be used as a final irrigant during root canal treatment with the dual benefit of removing the smear layer and inhibiting bacterial recolonization on root dentin.