• 한국소음진동공학회논문집
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• 제16권11호
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• pp.1108-1114
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• 2006

Underwater acoustic transducers can be exposed to a underwater explosive shock caused by various types of underwater weapon. So, a robust anti-shock design is required for transducers to endure the underwater explosive shock. To check the anti-shock characteristics of a transducer, underwater explosive shock test is needed. The conditions of underwater explosive shock test are set up referring to various oversea explosive shock test specifications, and the explosive shock pressure values are calculated according to those conditions. Transient analyses art: carried out for two kinds of underwater acoustic transducer model to verify the anti-shock characteristics. The applied model has robust anti-shock characteristics enough to endure the explosive shock up to 2300 psi. In the future, the transducer design should be certified through the fields test, and modified if needed.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5779-5785
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• 2015

The present study was designed to investigate cholangiocarcinoma (CCA) antibodies in hamster serum. Hamster CCA cell lines were processed using sodium dodecyl sulfate-polyacrylamide gel electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. A candidate biomarker was confirmed by immunoprecipitation and western blot, and was further analyzed using ELISA and sera from normal control hamsters, hamsters with opisthorchiasis and hamsters with various stages of CCA, as well as from CCA patients and healthy individuals. One candidate marker was identified as $HSP90{\alpha}$, as indicated by a high level of anti-$HSP90{\alpha}$ in hamster CCA sera. It was found that the levels of anti-$HSP90{\alpha}$ were specifically elevated in the sera of hamsters with CCA compared with other groups and progressively increased with the clinical stage. At the cut-off point of 0.4850 on the receiver operating characteristic curve, anti-$HSP90{\alpha}$ could discriminate CCA from healthy control groups with a sensitivity of 76.2%, specificity of 71.4% and total accuracy 75.5%. In the present study, we have shown that anti-$HSP90{\alpha}$ may be a potential useful serum biomarker to discriminate CCA cases from healthy persons.

• 소음진동
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• 제8권5호
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• pp.900-907
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• 1998

Rubber materials are extensively used in various machine design application, mainly for vibration/shock/noise control devices. Over the years an enormous effort has been put into developing procedures to provide properties of rubber material for design function. However, there are still a lot of difficulties in the understanding of dynamic characteristics of the rubber components in compression. In this paper, the dynamic characteristics of rubber materials for anti-vibration under compression were investigated. Dynamic and static tests for rubber material with 3 different hardness were performed. In dynamic tests, non-resonance method, impedance method, was used to obtain the complex modulus(storage modulus and loss factor) and the effects of static pre-strain on the dynamic characteristics were investigated. Also, a relation equation between linear dynamic and nonlinear static behavior of rubber material was discussed and its usefulness to predict their combined effects was investigated.

• Journal of Periodontal and Implant Science
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• 제33권2호
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• pp.179-191
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• 2003

Since periodontal infections are suggested as risk factors for the development of cardiovascular diseases, the present study was performed to evaluate the T cell immune responses specific to Pophylomonas gingivalis(P. gingivalis) heat shock protein(hsp) 60 and T-cell and B-cell epitope specificities for P. gingivalis hsp60 in atherosclerosis. Anti-P, gingivalis IgG antibody titers were elevated in all patients. We could establish P. gingivalis hsp-specific T cell lines from the atheroma lesions, a mixture of $CD4^+$ and $CD8^+$ cells producing the cytokines characteristic of both Th1 and Th2 subsets. of 108 overlapping synthetic peptides spanning whole P. gingivalis hsp60 molecule, ten peptides with common epitopes specificities for both T-cell and B-cell were identified. it was concluded that P. gingivalis hsp60 might K involved in the immunoregulatory process of atherosclerotic diseases with epitope specificities.

• 대한화장품학회지
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• 제30권4호
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• pp.471-477
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• 2004

피부 세포는 외부의 유해 요소 즉, 스트레스 환경에 노출되었을 때 세포 자신을 보호하기 위하여 다양한 방어 및 복구 체계를 가지고 있는데 그 중 하나가 보호단백질인 열충격단백질 70 kDa의 발현이다 Glucuronic acid를 피부세포에 다양한 농도로 전처리한 다음 유해자극(열, 활성산소)을 주었을 경우, western blottting을 통해 $0.12\%$ 농도에서 세포 내 열충격단백질이 발현됨을 알 수 있었다 그리고 confocal microscopy 및 세포생존율 실험을 이용하여 열 및 활성 산소에 대한 우수한 세포보호 효과를 확인하였다. 또한 마우스 피부를 이용하여 glucuronic acid 및 수중유(O/W)형 에멀젼에 적용하였을 때 경피 흡수 양상을 비교한 결과, glucuronic acid는 빠른 경피흡수거동을 보였다(투과속도 $0.83114 mg/cm^2/h,$ 지연시간 1.2 h, 분배계수 0.114). 에멀젼에서는 투과속도는 $0.04153{\;}{\mu}g/cm^{2}/h,$ 누적투과량은 $1456.25{\;}{\mu}g/cm^{2}$로 감소하였지만 지연시간은 2.48 h으로 증가하였고 지속적인 경피흡수(서방성)를 보였다.

• 융합신호처리학회논문지
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• 제4권2호
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• pp.53-60
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• 2003

무게중심이 높은 차량은 코너링 시에 전복되는 위험을 방지하기 위해 서스펜션 롤 강성이 매우 커야 한다. 어떤 경우에는 효과적인 롤 강성이 주로 타이어 컴플라이언스에 의해 결정되는데, 그러한 경우에는 히브(heave) 진동의 감쇠를 위해 사용되는 쇽업쇼바는 롤 진동을 억제하는 데에는 별다른 효과가 없다. 따라서, 차량의 측면에 돌풍이 불거나 차량이 불규칙한 도로면을 통과하게 될 경우 차량이 좌우로 심하게 흔들리게 된다. 본 연구에서는 무게중심이 높은 차량의 안정성을 향상시키기 위해서 롤 모드 상에서 댐핑을 증가시킬 수 있는 제어기법이 제안되었다. 롤 운동의 댐핑을 제공하기 위해 요구되는 궤환신호로 앞 또는 뒤 또는 앞 뒤 바퀴의 조향각이 사용되었다. 그 이유는 그 신호들이 롤 운동과 매우 밀접하게 관련이 있기 때문이다. 제안된 제어기법은 중고속에서 매우 효과적이고 쇽업쇼바와는 달리 외적 입력에 대해 외란 모멘트를 생성하지 않고 롤 모드를 안정화시키는 것이 가능하다. 이론적으로 제시된 제어기법에 대한 타당성을 컴퓨터 시뮬레이션으로 확인하였다.

• 한국패션뷰티학회지
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• 제3권1호
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• pp.1-12
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• 2005

The purpose of this thesis is to study the formative characteristics and symbolism shown in Rock stars' hairstyles through rock music to have influenced youth culture. There were a D.A style and a mop top style which included the youth characteristic to seek a new desire and value as the hairstyles of Rock & Roll stars, along with the characteristics of Rock & Roll music to represent the feeling of teenagers in 1950's at that time unlike the previous music due to high beats mixed with Rhythm & Blues (R & B) and Country music, and use of electronic guitars. We can see the desire for challenge and freedom against the then present regime, shouting love and peace, and resistance in the Psychedelic Rock music stars' hairstyle, which are untrimmed and disheveled, that is, natural. We can find explosiveness in Mohican and Spike style of Punk Rock stars playing fierce and aggressive music, along with words including indignation and assertion against the society's regime. The Artistic characteristic is implied in the following hairstyles: Glam Rock stars' hairstyle, a man's long-haired but a little long crew-cut style to reduce the bulky feeling and to give a bisexual, visible shock with hair dyed in orange to emphasize magnificence, and Punk Rock stars' hairstyle showing beauty in their own way with expression of anti-beauty to intentionally look ugly. Like this, the 20th Century's Rock music and youth culture are closely associated each other, and showed a new style, and played a leading role in street fashion, which became a momentum to much influence high fashion as a look of the 20th century modern fashion.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2009년도 제38회 동계학술대회 초록집
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• pp.44-45
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• 2010

We are currently conducting studies on culturing and biocompatibility assessment of various cells such as neural stem cells and induced pluripotent stem cells(IPS cells) on carbon nanotube (CNT), on nerve regeneration electrodes, and on silicon wafers with a focus on developing nerve integrated CNT based bio devices for interfacing with living organisms, in order to develop brain-machine interfaces (BMI). In addition, we are carried out the chemical modification of carbon nanotube (mainly SWCNTs)-based bio-nanosensors by the plasma ion irradiation (plasma activation) method, and provide a characteristic evaluation of a bio-nanosensor using bovine serum albumin (BSA)/anti-BSA binding and oligonucleotide hybridization. On the other hand, the researches in the case of "novel plasma" have been widely conducted in the fields of chemistry, solid physics, and nanomaterial science. From the above-mentioned background, we are conducting basic experiments on direct irradiation of body tissues and cells using a micro-spot atmospheric pressure plasma source. The device is a coaxial structure having a tungsten wire installed inside a glass capillary, and a grounded ring electrode wrapped on the outside. The conditions of plasma generation are as follows: applied voltage: 5-9 kV, frequency: 1-3 kHz, helium (He) gas flow: 1-1.5 L/min, and plasma irradiation time: 1-300 sec. The experiment was conducted by preparing a culture medium containing mouse fibroblasts (NIH3T3) on a culture dish. A culture dish irradiated with plasma was introduced into a $CO_2$-incubator. The small animals used in the experiment involving plasma irradiation into living tissue were rat, rabbit, and pick and are deeply anesthetized with the gas anesthesia. According to the dependency of cell numbers against the plasma irradiation time, when only He gas was flowed, the growth of cells was inhibited as the floatation of cells caused by gas agitation inside the culture was promoted. On the other hand, there was no floatation of cells and healthy growth was observed when plasma was irradiated. Furthermore, in an experiment testing the effects of plasma irradiation on rats that were artificially given burn wounds, no evidence of electric shock injuries was found in the irradiated areas. In fact, the observed evidence of healing and improvements of the burn wounds suggested the presence of healing effects due to the growth factors in the tissues. Therefore, it appears that the interaction due to ion/radicalcollisions causes a substantial effect on the proliferation of growth factors such as epidermal growth factor (EGF), nerve growth factor (NGF), and transforming growth factor (TGF) that are present in the cells.