• Fibers and Polymers
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• 제7권3호
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• pp.255-261
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• 2006

There is increasing interest in the many beneficial aspects of green tea to human such as anti-carcinogenic, anti-aggregant, anti-allergic, anti-bacterial, anti-mutagenic, and anti-oxidant activities. Besides these beneficial aspects, it has been reported that green tea ingredients, especially polyphenolic families (i.e., catechin), have some UV protection property both in vivo and in topical applications. In this study, green tea extract was used as a dyeing stock for cotton and the UV protection property of the dyed cotton fabric was examined. To increase the affinity of cotton fiber to the polyphenolic components in the green tea extract, a natural biopolymer, chitosan, was used as mordanting agent. The effects of chitosan concentration in mordanting on the dyeing characteristics and the UV protection property were examined. Chitosan mordanted green tea dyed cotton showed better dyeing characteristic and higher UV protection property compared with the unmordanted green tea dyed cotton. As the chitosan concentration in mordanting increased, the dyeing efficiency and the UV protection property also increased. Therefore, adapting chitosan mordanting in green tea dyeing can increase the UV protection property of cotton fabrics to some extent.

• 펄프종이기술
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• 제36권5호
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• pp.36-43
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• 2004

The behaviors of deterioration in the mechanical and optical properties of paper during sunlight exposure are mainly attributed to UV irradiation. The effect of different additives (anti-UV agents) on paper properties during exposure was studied. The results showed negligible changes in the mechanical properties of samples prepared with two different ways, whereas the shielding ability was increased when the additives were applied to the surface of hand sheets. Also, the paper which is treated with anti UV agents can keep freshness more effectively of agricultural products from UV irradiation.

• 한국동물생명공학회지
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• 제34권1호
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• pp.20-29
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• 2019

Soy isoflavones have been reported to possess many physiological activities such as antioxidant activity and inhibition of cancer cell proliferation. This study investigated the photoprotective effects of soybean extract in human fibroblast cell line and hairless mice model. Human fibroblast was treated with soybean extract before and after ultraviolet B (UVB; 290-302 nm) irradiation. In the soybean extract treated group, the cells showed better resistance to ultraviolet (UV) than control group. The amount of type I collagen recovered from the soybean treated group was higher than the vehicle group exposed to UV-induced damage. Moreover, increased expression of metalloproteinases-1 as a result of UV irradiation was suppressed by the soybean extract. Female mice were orally administered soybean extract and irradiated with UVB light for 8 weeks. The effects of the soybean extract on the skin appearance, collagen deposition and epidermal thickness in the UV-damaged mouse skin were analyzed using histopathological methods. In soybean extract treated group, the skin had a better morphology than that of the control group. Furthermore, the amount of type I collagen was increased and overexpression of MMP-1 was reduced in the soybean extract group compared to vehicle group. Additionally, up-regulation of pro-inflammatory cytokines induced by UV irradiation was suppressed by dietary soybean extract treatment. It appears that soybean extract had a photoprotective effect, including anti-aging and anti-inflammatory effect, from UV-induced damage in not only human fibroblast, but also hairless mice. We confirmed that these effects were possibly due to promotion of collagen synthesis and inhibition of MMP-1 expression.

• 한국산학기술학회논문지
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• 제15권7호
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• pp.4272-4278
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• 2014

광노화의 주요 요인인 자외선으로부터 피부를 보호하는 것은 피부노화를 막는 중요한 해결책 중 하나이다. 이를 위해 자연친화적 친환경적인 다양한 형태의 소재개발이 필요한 실정이다. 이에 본 연구는 미세조류(Chlamydomonas hedleyi.)로부터 Mycosporine-like amino acid (MAA)를 분리 정제 하여 인간 피부세포에서 UV protection 효과를 확인하였다. MAAs 중 porphyra-334를 분리하여 피부세포에서 UV protection 및 항염 효능을 시험하였고 그 결과 porphyra-334가 UV로부터 피부세포를 보호하여 cell viability가 약 26% 정도 증가하였고 COX-2 발현 40% 이상 저해함을 통해 항염 효능을 확인하였다. 이를 통해 porphyra-334의 자외선 차단용 소재뿐 아니라 항염 관련 소재로서의 가능성을 확인할 수 있었다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2003년도 Annual Meeting of KSAP : International Symposium on Pharmaceutical and Biomedical Sciences on Obesity
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• pp.110-110
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• 2003

It is well-documented that decreased antioxidant defense system by ultraviolet(UV) irradiation is the most important reason to induce the skin aging, especially photoaging. Chlorogenic acid(CA), a nonflavonoid catecholic compound, is present in the diet as part of fruits, tea, coffee and wine and has been reported to have anti-inflammatory, antimutagenic and anticarcinogenic activities. In this study, we examined the effects of CA on the UV -induced photoaging. Firstly, we investigated the protective effect of CA on antioxidant defense system in HaCaT human keratinocytes after UV irradiation treatment. UV irradiation decreased antioxidant defence enzyme activities of superoxide dismutase, catalase and GSH contents, which were restored by CA. To elucidate the effect of CA, 1% of CA and vehicle were applied to human buttock skin before and after UV irradiation (2MED). CA prevented UV -induced matrix metalloproteinase-1 mRNA expression and procollagen mRNA depression. And CA also increased CD1a(Langerhans cell) expression significantly. Our results suggest that CA has protective effects on UV -induced photoaging by increasing cellular antioxidant defense system. Therefore, CA may be a useful anti-aging agent for cosmetic purpose.

• 한국산학기술학회논문지
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• 제11권2호
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• pp.608-613
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• 2010

본 연구는 건축용 바닥재로 널리 이용되는 PVC 상재의 표면을 열에 의한 손상으로부터 보호하기 위하여 기존에 사용하는 광경화형 우레탄-아크릴 수지에 내열성(anti-cigar burning)을 향상시킨 광경화형 수성도료 개발에 관한 것이다. PVC 바닥상재용으로 사용되는 내열기능성이 없는 우레탄-아크릴 수지에 인계화합물을 주원료로 합성한 내열재, 구아니딘을 주원료로 합성한 내열재, 일시적 방염제로 사용되는 제 2인산암모늄을 수지의 양 대비 함량(wt%)을 10, 20, 30%로 변화하여 첨가한 후 배합하여 수지의 내열성을 향상시킨 코팅액을 제조하였다. 제조한 코팅액은 코팅층의 두께조절이 가능한 Bar-coating을 사용하여 PVC 바닥상재에 코팅한 후, 내열성, 부착력, 내화학성, 코팅두께 등의 코팅층 표면물성을 평가하였다. 연구결과, 수지에 인계화합물을 주원료로 합성한 내열재 30%를 혼합하여 제조한 코팅액을 Bar-coater No.12로 코팅한 코팅표면이 열에 의한 손상이 가장 적고, 부착력 100%, 내화학성 양호로 가장 좋은 물성을 보였다. 전반적으로 내열재 함량이 높고, 코팅 두께가 두꺼울수록 내열성이 우수한 것으로 나타났다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2005년도 춘계학술대회
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• pp.131-148
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• 2005

This study is peformed to investigate the effect of water extract from Vaccinium uliginosum L., on melanin production in B 16 melanoma cells, procollagen production and matrix metalloproteinase-1(MMP-1) inhibition in human fibroblast cells. One hundred grams of the Vaccinium uliginosum L. was extracted with 2000 mL of water($90^{\circ}C$, 16h, 2times). The water extracts were lyophilized and stored at $4^{\circ}C$ until used. Dry weight yields of extracts of Vaccinium uliginosum L. were $3\%$(w/w). Extracts from Vaccinium uliginosum L. showed scavenger activities on DPPH radical, superoxide anion radical, hydroxyl radical, hydrogen peroxide and singlet oxygen radical. And these substances inhibited release of cyiokines from human keratinocyte after UV B exposure. Therefore we confirmed that extracts from Vaccinium uliginosum L. had antioxidative effect. These substances inhibited purified tyrosinase activity and melanogenesis in B 16 melanoma cells treated/untreated IL-$1{\alpha}$. Moreover this extract stimulated procollagen production and inhibited MMP-1 production in human fibroblast cells treated/untreated IL-$1{\beta}$. Therefore we confirmed that extracts from Vaccinium uliginosum L. had whitening effect. And these substances decreased degree of wrinkle in hairless mouse skin that induced by UV B irradiation. Therefore we confirmed that extracts from Vaccinium uliginosum L. had anti-wrinkle effect. From the above results, it is possible that Vaccinium uliginosum L. may be developed to be an anti-melanogenesis agent and anti-wrinkle agent.

• Korean Chemical Engineering Research
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• 제59권2호
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• pp.165-173
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• 2021

눈부심 방지(Anti-glare, AG) 코팅 필름은 액정 디스플레이, LED 조명, 터치 패널 등 다양한 디스플레이 분야에 적용되고 있다. 본 연구에서는 UV 경화형 코팅 용액 내에 충전제로써 마이크로미터 크기의 실리카 입자를 첨가하여 눈부심 방지 효과를 부여하고자 하였다. 이 과정 중 실리카 입자의 크기, 함유량, 교반 시간, 다른 크기의 실리카 입자의 혼합 비율이 코팅 도막의 haze 값과 가시광선 투과도에 미치는 영향을 조사하였다. 그 결과 실리카 입자의 크기가 클수록, 또한 실리카 입자의 함유량이 증가할수록 haze 값은 증가하나, 가시광선 투과도는 감소하였다. 반면 교반 시간은 haze 값과 투과도에 큰 영향을 주지 못하였다. 또한 큰 크기의 실리카의 혼합 비율이 증가할수록 haze 값은 증가하나, 이와 반대로 가시광선 투과도는 감소하는 것을 확인할 수 있었다.

• Journal of Photoscience
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• 제9권2호
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• pp.221-224
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• 2002

Carcinogenesis can be theoretically divided to intiation step and promotion step. Intiation associates with genetic alterations including p53 tumor suppressor gene and ras oncogene. Promotion involves in clonal expansion of of an initiated cell by epigenetic mechanism, mainly through signal transduction and gene expression. Ultraviolet light (UV) acts as both initiator and promoter. Initiation is closely related with DNA damage induced by UV, including cyclobutane pyrimidine dimers, (6-4) photoproducts and 8-hydroxy-2'-deoxyguanosine. Cyclobutane pyrimidine dimers and (6-4) photoproducts are directly induced by UV, while 8-hydroxy-2'-deoxyguanosine is induced indirectly by the reactive oxygen species. Because initiation is an irreversal genetic event, while promotion is a reversal and epigenetic event, to know the molecular mechanisms of tumor promotion in UV-carcinogenesis is crucial to develop preventive medicine and suppress UV-carcinogenesis. Because ROS is also involved in signal transduction of the cell, anti-oxidant could be the good candidate of anti-promoting agent. Here, we describe the suppressive effect of UV-carcinogenesis by various anti-oxidant including olive oil. In addition, we discuss about the mechanism of UVB-induced expression of cyclooxygenase-2, which might be a representative molecule involved in promotion of UV-carcinogenesis.

• 통합자연과학논문집
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• 제9권1호
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• pp.16-22
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• 2016

The optical and physical and characteristics of hydrogel ophthalmic lens polymerized with addition of 2,6-difluoropyridine, SiPc(silicon 2,9,16,23-tetra-tert-butyl-29H31H-phthalocyanine dihydroxide) and nanodiamond in the basic hydrogel material were evaluated. In particular, the utility of 2,6-difluoropyridine, SiPc and nanodiamond as a hydrogel ophthalmic lens material was investigated. 2,6-difluoropyridine, SiPc and nanodiamond were used as additives. And also, 2-hydroxyethyl methacrylate, acrylic acid, methyl methacrylate and a cross-linker EGDMA were copolymerized in the presence of AIBN as an initiator. The refractive index of 1.4348~1.4361, water content of 33.30~34.02%, UV-B transmittance of 4.77~67.50%, UV-A transmittance of 1.45~89.19% and visible transmittance of 32.12~92.21% were obtained. The results of hydrogel lens containing 2,6-difluoropyridine (add 5%) showed antibiosis for staphylococcus aureus. The produced copolymer is suitable for hydrogel soft ophthalmic lenses with antibiotic and anti-UV effect.