• 제목/요약/키워드: Anti-Korean

검색결과 18,954건 처리시간 0.052초

산초 추출물의 S. mutans 항균활성 및 항산화 효능 연구 (A Study on the Anti-microbial Effect on S. mutans and Anti-oxidant Effect of Zanthoxylum pericarpium Extract)

  • 이상곤;박찬익
    • 대한본초학회지
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    • 제26권4호
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    • pp.181-185
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    • 2011
  • Objectives : The Zanthoxylum pericarpium has been used as oriental spicy seasoning and a medicinal plant from old times. This study was performed to determine the anti-oxidant efficacy of Zanthoxylum pericarpium extract and the anti-microbial effects. Methods : We got Zanthoxylum pericarpium extract using PSE (pressurized solvent extraction) method. The anti-microbial effect of Zanthoxylum pericarpium extract was assessed on Streptococcus mutans(S. mutans) and anti-oxidant effect of the extract was assessed by measuring DPPH radical scavenging activity and SOD like activity. Results : 1. Zanthoxylum pericarpium extract had high anti-microbial activity on S. mutans. 2. DPPH radical scavenging activity significantly increased in the Zanthoxylum pericarpium extract. 3. SOD like activity also significantly increased in the Zanthoxylum pericarpium extract. Conclusions : The PSE extract from Zanthoxylum pericarpium has good anti-microbial and anti-oxidant effects in a concentration-dependent manner.

숙지황 추출물의 항염증 작용을 통한 항우울 효과 (The Anti-depressive Effect of Rehmanniae Radix Preparata via Anti-inflammatory Activity)

  • 김응선;정명수
    • 대한한의학회지
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    • 제43권1호
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    • pp.99-111
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    • 2022
  • Objectives: Rehmanniae Radix Preparata (RRP) has been used as a traditional remedy to treat gynecology and endocrine diseases. Recently, studies on antioxidant and anti-inflammatory effects of RRP have been reported, so it was judged that RRP extracts would have an anti-depressive effect. Methods: We investigated the anti-neuroinflammatory and anti-depressive effect of RRP on lipopolysaccharide (LPS)-induced depression and LPS-stimulated BV2 microglia. RRP inhibited the LPS-stimulated excessive release of nitrite in the BV2 cells. RRP also significantly inhibited the inflammatory cytokines such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta and IL-6 in LPS-stimulated BV2 microglial cells. Results: RRP significantly suppressed the LPS-induced mitogen-activated protein kinase (MAPKs) and nuclear factor (NF)-𝜅B activation. In addition, administration of RRP not only inhibited the immobility time in the forced swimming test (FST) but also increased the total travel distance in the open field test (OFT). Also, RRP inhibited the elevation of TNF-alpha, IL-1beta, and IL-6 in brain of LPS-injected mice. Conclusions: Considering the overall results, our study showed that RRP exhibited the anti-neuroinflammatory and anti-depressive activities via deactivation of MAPKs and NF-𝜅B.

Contrasting Correlation in the Inhibition Response of ADP-induced Platelet Aggregation and the Anti-coagulant Activities of Algal fucoidans Derived from Eisenia bicyclis and Undaria pinnatifida sporophylls (Mekabu)

  • Jeong, Eui-Sook;Yoon, Yeon-Hee;Kim, Jong-Ki
    • Fisheries and Aquatic Sciences
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    • 제12권3호
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    • pp.194-202
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    • 2009
  • Sulfated fucans are known to have both anti-thrombotic and anti-coagulant activities. In this study, the variation in platelet aggregation and anti-coagulant activities was investigated in vitro with regard to administered dose, molecular weight distribution, sulfate content, and sugar composition in two algal fucoidans from Eisenia bicyclis and Undaria pinnatifida sporophylls (Mekabu). The anti-coagulant activity largely correlated with sulfate content and with molecular weight distribution in a dose-dependent manner. However, both fucoidans demonstrated inhibitory responses to ADP-induced platelet aggregation in dose- and structure-dependent manners that contrasted with the anti-coagulant activity. Neither molecular weight distribution nor sulfate content greatly affected platelet-aggregation inhibition (PA-inhibition) by the fucoidan fractions, whereas anti-coagulant activity was sensitive to these structural factors. Interestingly, an E. bicyclis fucoidan fraction exhibited almost complete PA-inhibition at a treatment dose of 500 mg/mL while retaining weak anti-coagulant activity. In conclusion, these observations suggest that fucoidan may be a useful anti-thrombotic or anti-platelet agent in various arterial thrombotic disorders, including post-vascular intervention with controlled bleeding complications, due to its anti-coagulant modulating activity.

ANTI-DIARRHEA AND SPASMOLYTIC ACTIVITIES OF A HERBAL ANTI-DIARRHEA FORMULA

  • Ryu, Seung-Duk;Park, Chang-Shin;Baek, Sun-Hye;Hwang, Sung-Yeoun;Chung, Woon-Gye
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2002년도 Current Trends in Toxicological Sciences
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    • pp.115-115
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    • 2002
  • The anti-diarrhea and spasmolytic activities of Soonkijangquebo (SKJQB), a Korean herbal anti-diarrhea formulation, were subjected to pharmacological evaluation. SKJQB, at a dose of 50\ulcorner200 mg/kg, inhibited castor oil-induced diarrhea in mice. The median effective dose (ED50) of the anti-diarrhea effect was 93 mg/kg.(omitted)

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Anti-DDoS SW 성능평가에 관한 연구 (Research of Anti-DDoS SW Efficiency Test)

  • 이재근;조인준;신석규;김선주
    • 한국정보통신학회:학술대회논문집
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    • 한국해양정보통신학회 2009년도 추계학술대회
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    • pp.363-367
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    • 2009
  • 최근의 인터넷 공격의 화두는 네트워크의 트랙픽을 이용한 분산 서비스 거부 (DDoS : Distributed Denial of Service) 공격이다. 정부 기관과 기업들은 DDoS 공격을 막기 위한 대응책으로 DDoS 방어 전문 장비인 Anti-DDoS SW를 도입하고 있다. 하지만 현재 Anti-DDoS의 객관적인 품질평가 기준이 없어 Anti-DDoS SW를 개발한 회사들이 제시하는 객관적이지 않은 정보에 의존하여 Anti-DDoS SW를 도입하고 있다. Anti-DDoS SW 시장규모가 커지면서 Anti-DDoS SW의 객관적인 품질평가가 요구 되고 있다. 본 논문에서는 DDoS 공격을 막기 위한 Anti-DDoS SW 제품 도입시 고려할 성능평가 요소에 대해 기술하였다.

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제주지역 일개 종합병원에서 동정된 비예기항체의 실태조사 (Survey of Unexpected Antibodies Identified at a General Hospital in Jeju)

  • 정무상;이규택;조영국
    • 대한임상검사과학회지
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    • 제49권4호
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    • pp.390-394
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    • 2017
  • 비예기항체(unexpected antibody)는 ABO 혈액형 항체와는 달리 존재 여부를 미리 예측할 수 없는 항체로 주로 임신이나 수혈 등에 의해 다른 적혈구 항원에 노출됨으로써 발생하는 면역항체로서, 비예기항체는 해당 항원을 가진 수혈된 적혈구를 파괴하여 급성 및 지연성 용혈성부작용이나 신생아용혈성질환 등의 수혈부작용을 유발할 수 있다. 2014년 1월부터 2016년 12월까지 3년간 제주특별자치도 종합병원에 비예기항체 선별검사가 의뢰된 10,360명의 혈청 검체를 대상으로 하였으며, 의뢰된 비예기항체 선별결과 양성 결과를 보인 87 검체를 대상으로 조사하였다. 비예기항체가 선별되었던 87건 중 비예기항체 동정검사를 수탁검사기관으로 의뢰한 41 검체(0.40%) 대상으로 분석한 결과 비특이항체가 8건(19.51%), 자가항체가 3건(7.32%)이었다. 이들을 제외하고 항체가 동정된 것은 anti-E가 8건(19.51%), anti-E, anti-c 복합항체가 6건(14.63%), $anti-Le^a$, $anti-Le^b$ 복합항체가 3건(7.32%), $anti-Le^a$$anti-Le^b$가 각각 2건(4.88%)으로 조사되었다. 단일항체로는 anti-D, $anti-Di^a$, $anti-Fy^b$, $anti-Jk^a$, $anti-Jk^b$, anti-M, anti-P1이 각각 1건(2.44%)로 나타났으며 복합항체로는 anti-C+anti-D, anti-E+anti-c+$anti-Jk^b$가 각각 1건(2.44%)로 조사되었다. 단일항체가 동정된 검체는 19건(46.34%), 복합항체가 동정된 검체는 11건(26.83%)로 나타났다. 제주지역의 종합병원은 제주시와 서귀포시에 위치한 종합병원 7개 기관이 있으며, 모두 비예기항체 선별검사를 시행하고 있으며, 검사방법으로는 모든 검사실에서 Ortho BioVue system을 이용한 원주응집법으로 검사를 시행하고 있다. 하지만 비예기항체 동정검사는 외부수탁기관에 의뢰하고 있는 실정이다. 이번 연구는 최근 3년간 제주도내 종합병원 1개 기관에서의 동정된 비예기항체 빈도와 분포를 분석하였지만, 점차적으로 제주도내 다문화가정과 외국인 근로자가 증가 추세에 있어 향후 제주지역에 분포한 다수의 종합병원에서 동정되는 비예기항체의 빈도와 분포를 비교 분석한다면 의미가 있는 연구가 될 것이라고 사료된다.

현대패션에 나타난 Anti Couture 경향 연구 (A Study on Anti Couture in Contemporary Fashion)

  • 변영희;채금석
    • 한국의류학회지
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    • 제33권7호
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    • pp.1098-1108
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    • 2009
  • This study finds the meaning of Anti Couture in the examination of the tendency and characteristics of aesthetics sense of Anti Couture in Contemporary Fashion. Anti Couture disregards the traditional composition and takes some subcultural elements, moreover, have the Anti-decoration characteristics of disproportion, disharmony, asymmetry, inperfection, and irregularity such as Japanese fashion. This study analyzed 600 works from 2000 S/S to 2008 S/S to figure out the Anti Couture to summarize the eclectic, humorous, avant-garde, poor, and minimal tendencies. The characteristics of the aesthetics sense of Anti Couture according to the tendency are analyzed into ambiguity, deformation, eclecticism, deconstruction, and artless art.

화피 추출물이 염증 및 알레르기 반응에 미치는 영향 (Effect of Phellinus igniarius Quel Extract on the Anti-inflammatory, Anti allergy, Anti-oxidant, Anti-wrinkle reaction)

  • 정지영;정현아
    • 한방안이비인후피부과학회지
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    • 제23권3호
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    • pp.42-65
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    • 2010
  • Objectives : Betula platyphylla var. japonica extract (BPE) was used to determine the modulation of cytokine secretion, the activation of inflammatory and allergic factor and the inhibition of gene expression. Inflammatory and allergic cytokines as IL-$1{\beta}$, IL-2, IL-4, IL-5, IL-6, IL-8, TNF-${\alpha}$, NO and COX-2 were measured to use effectively on improvement or treatment of atopic dermatitis. Methods : We used NC/Nga mouse induced by atopic dermatitis to observe the effects of BPE on the weight, water and feed, blood test, weight of organs, histological change, total IgE and histological change of main organs. Results : BPE is effective on anti-inflammatory and allergic reaction. However, further study is needed to prove which component of BPE indicates effective pharmacological action. Conclusions : The above results suggest that Phellinus igniarius Quel extract could be applicable for improvement of several skin functions.

Bioinspired Nanoengineering of Multifunctional Superhydrophobic Surfaces

  • Choi, Chang-Hwan
    • 한국표면공학회:학술대회논문집
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    • 한국표면공학회 2015년도 추계학술대회 논문집
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    • pp.102-133
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    • 2015
  • Nature, such as plants, insects, and marine animals, uses micro/nano-textured surfaces in their components (e.g., leaves, wings, eyes, legs, and skins) for multiple purposes, such as water-repellency, anti-adhesiveness, and self-cleanness. Such multifunctional surface properties are attributed to three-dimensional surface structures with modulated surface wettability. Especially, hydrophobic surface structures create a composite interface with liquid by retaining air between the structures, minimizing the contact area with liquid. Such non-wetting surface property, so-called superhydrophobicity, can offer numerous application potentials, such as hydrodynamic drag reduction, anti-biofouling, anti-corrosion, anti-fogging, anti-frosting, and anti-icing. Over the last couple of decades, we have witnessed a significant advancement in the understanding of surface superhydrophobicity as well as the design, fabrication, and applications of superhydrophobic coatings/surfaces/materials. In this talk, the designs, fabrications, and applications of superhydrophobic surfaces for multifunctionalities will be presented, including hydrodynamic friction reduction, anti-biofouling, anti-corrosion, and anti-icing.

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7종 한약재 추출물의 항산화 및 항염증 효과와 이를 이용한 방제 구성에 대한 고찰 (Anti-oxidative and Anti-inflammatory Effect of 7 Herbal Extracts and Methods of Herbal Formula Compositioning)

  • 박정후;박주연;박선동
    • 대한한의학방제학회지
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    • 제22권2호
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    • pp.87-103
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    • 2014
  • Objectives : Herbal formulas are complicated to analyze and difficult to compose because of its mixed, complex features. So we discussed about how to compose herbal formulas effective and efficient by analyzing various effectiveness of each herbal extracts. Methods : To evaluate the effectiveness of herbal formula, anti-oxidative and anti-inflammatory effectiveness were mathematically analyzed. DPPH, superoxide anions, Nitric Oxide scavenging activity was measured to evaluate the effectiveness of 7 herbal extracts. And next, cytotoxic activity of extracts on RAW 264.7 cells were measured using MTS assay. To asses anti-inflammatory effect, nitric oxide and $PGE_2$ production were measured. Based on these anti-oxidative and anti-inflammatory experiment result, mathematical analyzation were carried out with constOptm function, and determined efficacy-maximizing ratio. Results : This mathematical analysis based formula showed significantly outstanding effectiveness than other formulae. And estimated tendency of anti-inflammatory effectiveness was matched with real effectiveness. Conclusions : So, mathematical analysis can be available to evaluate and estimate the effectiveness of herbal formulae.