• Title/Summary/Keyword: Anomalies

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Genetics of kidney development: pathogenesis of renal anomalies

  • Hahn, Hye-Won
    • Clinical and Experimental Pediatrics
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    • v.53 no.7
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    • pp.729-734
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    • 2010
  • Congenital anomalies of the kidney and urinary tract (CAKUT) account for more than 50% of abdominal masses found in neonates and involve about 0.5% of all pregnancies. CAKUT has a major role in renal failure, and increasing evidence suggests that certain abnormalities predispose to the development of hypertension and cardiovascular disease in adulthood. To understand the pathogenesis of human renal anomalies, understanding the development of kidney is important. Diverse anomalies of the kidney corresponding to defects at a particular stage of development have been documented recently; however, more research is required to understand the molecular networks underlying kidney development, and such an investigation will provide a clue to the therapeutic intervention for CAKUT.

GPS Gravity Surveying for the Terrain Analysis at the Choogaryeong Rift Valley between Seoul and Cheolwon (서울-철원간 추가령곡의 지형분석을 위한 GPS 중력측정)

  • 이창호
    • Economic and Environmental Geology
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    • v.32 no.3
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    • pp.281-291
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    • 1999
  • This study presents the gravity data with GPS survrying and the geophysical profiles at the Choogaryeong Rift Valley. And in determing geoid by GPS measurement, survey control points (SCP) whoch built by the Republic of Korean Army are used. Seventy nine SCP and the two triangulation stations are reviewd by GPS. Digital terain model is under for terrain analysis. The analyses of the gravity surveying with GPS are as follows. The low values of the negative Bouguer anomalies represent the high elevation terrain. The Bouguer anomalies show the decrrasing trend toward the eastern part of the study area. Characteristics of free-air anomalies are related with terrain elevation. The regional gravity anomalies decreas toward the eastern part of the study area. The trends of variations are associated with the thermotectonic and geologic structure beneath the Choogaryeong Rift Valley. The most parts of the study area represent negative residual gravity anomalies due to the low dencity of sedimentary cover in the Rift Valley. There are three valleys and four mountains in the direction of NE-SW or NNE-SSW which are structured by the geological features.

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Anomaly Test for Ozone Concentration Data from National Air Monitoring Stations (오존 자동측정망 자료 중의 이상치 점검)

  • 김영성
    • Journal of Korean Society for Atmospheric Environment
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    • v.15 no.2
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    • pp.139-150
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    • 1999
  • The ozone concentrations measured at the National Air Monitoring Stations between 1990 and 1995 were reviewed to detect any anomalies in the measurements. By screening the cases, in which variation of the ozone concentration from the previous measured value is greater than 75ppb, 125 station-days were identified as the test cases for the anomaly test. Historical and parallel consistencies of the measured concentrations were examined by plotting data for each test case. The detected anomalies can be classified into four categories; single outliers, anomalous variations during the startup period, baseline rises, and fluctuations in th diurnal variations. Anomalies were detected in as many as 80 cases among 125 test cases. Because of these anomalies, the number of hours exceeding 100ppb in the areas other than the Greater Seoul Area(GSA) could decrease from 157 to 107. Further studies for developing the methodology for eliminating the abnormal monitoring data are warranted for the data from the National Air Monitoring Stations are official to the both inside and outside of the country.

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Improved Free-air Gravity Anomalies by Satellite Altimetry

  • Kim, Jeong-Woo;Roman, Daniel-R.
    • Korean Journal of Remote Sensing
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    • v.17 no.4
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    • pp.297-305
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    • 2001
  • Ocean satellite altimetry-implied free-air gravity anomalies have had the shortest wavelengths removed during the processing to generate the optimal solution between multiple radar altimeter missions. ERS-1 168day mission altimetry was residualized to a reference geoid surface generated by integrating Anderson & Knudsen’s free-air gravity anomalies for the Barents Sea. The altimetry tracks were reduced and filtered to extract the shortest wavelengths (between 4 and 111 km) from both ascending and descending tracks, respectively. These data were recombined using existing quadrant-swapping techniques in the wavenumber domain to generate a correlated, high frequency gravity field related to the local geologic sources. This added-value surface adjusted the reference free-air gravity anomalies to better reflect features in the gravity field at a wavelength related to the distance between altimetry ground tracks.

Congenital Anomalies of Head and Neck in Children (소아에서 발생하는 선천성 두경부 기형)

  • Lee, Kyeong-Geun;Jung, Poong-Man
    • Advances in pediatric surgery
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    • v.7 no.1
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    • pp.7-14
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    • 2001
  • Congenital anomalies of the head and neck region such as preauricular sinus and skin tag, thyroglossal duct cyst, branchial anomaly, cystic hygroma and dermoid cyst are common in pediatric population. It is important for pediatricians and pediatric surgeons to be familiar with the embryology and the anatomical characteristic of these lesions in order to diagnose and treat them properly. Three hundred and nineteen patients with congenital head and neck anomalies treated at Hanyang University Hospital between 1980 and 1999 were reviewed to determine the relative frequency of the anomalies and to analyze the method of management. Eight-four (25.1 %) of 335 lesions were preauricular sinus and skin tag, 81 (24.2 %) were thyroglossal duct cyst, 81 (24.2 %) branchial anomaly, 58 (17.3 %) cystic hygroma and 31 were (9.2 %) dermoid cyst. The male-to-female ratio was 1.4:1. Thyroglossal duct cyst most commonly present at 3-5years, however branchial anomalies commonly are diagnosed in children younger than 1 year. Preauricular sinus showed familial tendency in three patients and was bilateral is 33.8 %. Most head and neck anomalies in children have specific clinical and anatomical characterics. A careful history and physical examination is very useful for diagnosis and proper management. Experienced pediatric surgeons should do the initial surgery since the recurrence rate after incomplete surgical excision can be high.

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Fluctuations of Coastal Water Temperatures Along Korean and Japanese Coasts in the East Sea

  • KANG Yong-Q.;CHOI Seong-Won
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.21 no.6
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    • pp.351-360
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    • 1988
  • Based on historic data of monthly means of sea surface temperatures (SST) for 24 years $(1921\~1944) $ at 23 Korean and Japanese coastal stations in the East Sea (the Japan Sea), we analyzed spatio-temporal characteristics of coastal SST and SST anomalies. The means of SST at Korean coast are higher than those at Japanese coast of the same latitudes, and the annual range of SST at Korean coast are larger than those at Japanese coast. Empirical orthogonal function analysis shows that almost all $(96\%)$ of the SST fluctuations are described by simultaneous seasonal variations. The flurtuations of SST anomalies are small in the Korea Strait and large at the boundaries between the warm and told currents in the basin. The fluctuations of SST anomalies along Korean coast are correlated each other The same is true for SST anomalies along Japanese coast. However, there is only weak correlation between the SST anomalies at Korean coast and those at Japanese coast. Empirical orthogonal function analysis shows that $27\%$ of the coastal SST anomalies in the East Sea are described by simultaneous fluctuations, and $12\%$ of them are described by alternating fluctuations between Korean and Japanese coasts.

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Current concepts of vascular anomalies

  • Tae Hyung Kim;Jong Woo Choi;Woo Shik Jeong
    • Archives of Craniofacial Surgery
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    • v.24 no.4
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    • pp.145-158
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    • 2023
  • Vascular anomalies encompass a variety of malformations and tumors that can result in severe morbidity and mortality in both adults and children. Advances have been made in the classification and diagnosis of these anomalies, with the International Society for the Study of Vascular Anomalies establishing a widely recognized classification system. In recent years, notable progress has been made in genetic testing and imaging techniques, enhancing our ability to diagnose these conditions. The increasing sophistication of genetic testing has facilitated the identification of specific genetic mutations that help treatment decisions. Furthermore, imaging techniques such as magnetic resonance imaging and computed tomography have greatly improved our capacity to visualize and detect vascular abnormalities, enabling more accurate diagnoses. When considering reconstructive surgery for facial vascular anomalies, it is important to consider both functional and cosmetic results of the procedure. Therefore, a comprehensive multidisciplinary approach involving specialists from dermatology, radiology, and genetics is often required to ensure effective management of these conditions. Overall, the treatment approach for facial vascular anomalies depends on the type, size, location, and severity of the anomaly. A thorough evaluation by a team of specialists can determine the most appropriate and effective treatment plan.

Clinical disease characteristics according to karyotype in Turner syndrome (터너증후군에서 핵형에 따른 임상질환의 발병양상)

  • Yeo, Chae Young;Kim, Chan Jong;Woo, Young Jong;Lee, Dae Yeol;Kim, Min Sun;Kim, Eun Young;Kim, Jong Duck
    • Clinical and Experimental Pediatrics
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    • v.53 no.2
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    • pp.158-162
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    • 2010
  • Purpose : Turner syndrome (TS) is a disorder in which various anomalies can be accompanied, especially cardiovascular, renal, thyroid and auditory problems. The aim of this study is to identify the incidence of these disorders in patients with TS according to karyotype. Methods : We reviewed medical records of 90 patients with TS diagnosed by chromosomal analysis in 4 hospitals from Jan 1998 to Dec 2007. We evaluated these cases by prepared protocol of 4 medical problems.Results : The distribution of karyotype was 45,X (47.8%), mosaic pattern (34.4%) and structural aberration group (17.8%). Renal anomalies, cardiovascular anomalies, thyroid disorders and auditory problems are accompanied in 4.4%, 10.0 %, 11.1% and 5.6%, respectively. 45,X group had renal anomalies (7.0%), cardiovascular anomalies (18.6%), thyroid disorders (9.3%) and auditory problems (11.6%). Mosaic group had renal anomalies (3.2%), thyroid disorders (12.9%), no cardiovascular anomalies and auditory problems. Structural aberration group had cardiovascular anomalies (6.3%), thyroid disorders (12.5%) and no other 2 problems. Patients with 45,X group had a significant higher incidence of cardiovascular anomalies (P =0.025). Conclusion : Our results indicate that there are differences clinically according to karyotype of TS, especially in incidence of cardiovascular anomalies.

Clinical Approaches to Vascular Anomalies of the Lip

  • Ryu, Jeong Yeop;Lee, Joon Seok;Lee, Jeong Woo;Choi, Kang Young;Yang, Jung Dug;Cho, Byung Chae;Lee, Seok-Jong;Lee, Jong Min;Huh, Seung;Chung, Ho Yun
    • Archives of Plastic Surgery
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    • v.42 no.6
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    • pp.709-715
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    • 2015
  • Background The incidence of vascular anomalies in the head and neck is higher than in the extremities. It is especially common for vascular anomalies to involve the lip. The lips are a functionally and aesthetically important component of the head and neck area. A retrospective analysis of data from our vascular anomaly center was performed in order to understand the characteristics and treatment requirements of vascular anomalies of the lip and to establish which treatments are likely to lead to the best outcomes. Methods A retrospective review was performed of the medical records of patients diagnosed with vascular anomalies of the upper or lower lip from January 2001 to September 2013. Using clinical photographs, radiologic findings, and patient records, the diagnosis of each case and the location of the vascular anomaly were recorded, along with information about treatment and follow-up. Results A total of 1,606 patients were diagnosed with vascular anomalies over this time period, of whom 127 (7.9%) were found to have vascular anomalies in the lip only. Surgical treatment with or without embolization, sclerotherapy, laser therapy, medication only, and observation were the treatment strategies adopted in these cases. Conclusions Vascular anomalies of the lip should be diagnosed accurately. Radiologic diagnosis played a crucial role in treatment planning, and several techniques were used to treat vascular anomalies of the lip. When surgical excision is indicated for the correction of vascular anomalies of the lip, the aesthetic and functional characteristics of the lip should be considered.

Markov Chain Properties of Sea Surface Temperature Anomalies at the Southeastern Coast of Korea (한국 남동연안 이상수온의 마르코프 연쇄 성질)

  • Kang, Yong-Q.;Gong, Yeong
    • 한국해양학회지
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    • v.22 no.2
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    • pp.57-62
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    • 1987
  • The Markov chain properties of the sea surface temperature (SST) anomalies, namely, the dependency of the monthly SST anomaly on that of the previous month, are studied based on the SST data for 28years(1957-1984) at 5 stations in the southeastern coast of Korea. Wi classified the monthly SST anomalies at each station into the low, the normal and the high state, and computed transition probabilities between SST anomalies of two successive months The standard deviation of SST anomalies at each station is used as a reference for the classification of SST anomalies into 3states. The transition probability of the normal state to remain in the same state is about 0.8. The transition probability of the high or the low states to remain in the same state is about one half. The SST anomalies have almost no probability to transit from the high (the low) state to the low (the high) state. Statistical tests show that the Markov chain properties of SST anomalies are stationary in tine and homogeneous in space. The multi-step Markov chain analysis shows that the 'memory' of the SST anomalies at the coastal stations remains about 3 months.

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