• Imaging Science in Dentistry
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• v.47 no.4
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• pp.275-279
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• 2017

Soft tissue calcification is a pathological condition in which calcium and phosphate salts are deposited in the soft tissue organic matrix. This study presents an unusual calcification noted in the cartilaginous portion of the Eustachian tube. A 67-year-old woman presented for dental treatment, specifically for implant placement, and cone-beam computed tomography (CBCT) was performed. The CBCT scan was reviewed by a board-certified oral and maxillofacial radiologist and revealed incidental findings of 2 distinct calcifications in the cartilaginous portion of the Eustachian tube. To the authors' knowledge, no previous study has reported the diagnosis of Eustachian tube calcification using CBCT. This report describes an uncommon variant of Eustachian tube calcification, which has a significant didactic value because such cases are seldom illustrated either in textbooks or in the literature. This case once again underscores the importance of having CBCT scans evaluated by a board-certified oral and maxillofacial radiologist.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.2
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• pp.61.1-61.1
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• 2016

Black hole (BH) mass is a fundamental quantity to understand BH growth, galaxy evolution, and connection between them. Thus, obtaining accurate and precise BH mass estimates over cosmic time is of paramount importance. The rest-frame UV CIV ${\lambda}1549$ broad emission line is commonly used for BH mass estimates in high-redshift AGNs (i.e., $2{\leq}z{\leq}5$) when single-epoch (SE) optical spectra are available. Achieving correct and accurate calibration for CIV-based SE BH mass estimators against the most reliable reverberation-mapping based BH mass estimates is thus practically important and still useful. By performing multi-component spectral decomposition analysis to obtained high-quality HST UV spectra for the updated sample of local reverberation-mapped AGNs including new HST STIS observations, CIV emission line widths and continuum luminosities are consistently measured. Using a Bayesian hierarchical model with MCMC sampling based on Hamiltonian Monte Carlo algorithm (Stan NUTS), we provide the most consistent and accurate calibration of CIV-based BH mass estimators for the three line width characterizations, i.e., full width at half maximum (FWHM), line dispersion (${\sigma}_{line}$), and mean absolute deviation (MAD), in the extended BH mass dynamic range of log $M_{BH}/M_{\odot}=6.5-9.1$.

• Journal of Electrochemical Science and Technology
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• v.3 no.4
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• pp.159-164
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• 2012

Magnesium (Mg) deposition and dissolution behaviors of 0.2 M $MgBu_2-(AlCl_2Et)_2$, 0.5 M $Mg(ClO_4)_2$, and 0.4M $(PhMgCl)_2-AlCl_3$-based electrolytes with and without tris(pentafluorophenyl) borane (TPFPB) are investigated by ex situ scanning electron microscopy (SEM) and galvanostatic cycling of Mg/copper (Cu) cells. To ascertain the factors responsible for the anodic stability of the electrolytes, linear sweep voltammogrametry (LSV) experiments for various electrolytes and solvents are conducted. The effects of TPFPB as an additive on the anodic stability of 0.4M ($(PhMgCl)_2-AlCl_3$/THF electrolyte are also discussed.

• BMB Reports
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• v.46 no.11
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• pp.539-543
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• 2013

There is a correlation between obesity and the amount of brown adipose tissue; however, the molecular mechanism of brown adipogenic differentiation has not been as extensively studied. In this study, we performed a protein tyrosine phosphatase (PTP) profiling analysis during the brown adipogenic differentiation of mouse primary brown preadipocytes. Several PTPs, including PTPRF, PTPRZ, and DUSP12 showing differential expression patterns were identified. In the case of DUSP12, the expression level is dramatically downregulated during brown adipogenesis. The ectopic expression of DUSP12 using a retroviral expression system induces the suppression of adipogenic differentiation, whereas a catalytic inactive DUSP12 mutant showed no effect on differentiation. These results suggest that DUSP12 is involved in brown adipogenic differentiation and may be used as a target protein for the treatment or prevention of obesity by the regulation of brown adipogenic differentiation.

• The Journal of Korean Medicine
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• v.35 no.1
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• pp.41-49
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• 2014

Objectives: We propose a method to model and represent formulas in Korean medicine information systems. Methods: All the formulas were codified in the form of graphs representing the relationship between a formula and its constituents. To identify a unique formula in a graph, the formula's name, the book in which the formula was written, the book where the formula was extracted, and the page number in the extracted book are used. All the formulas and the relationship between formulas are modelled as an ontology based on graphs. Results: A formula search system was constructed using our ontology, which can represent formula information efficiently by grouping and filtering of formulas. Our formula model was also constructed as a mobile application. Conclusions: The information in our formula search system depends on our ontology. However, our model or our search scenarios could be extended according to formula information.

• BMB Reports
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• v.49 no.7
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• pp.388-393
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• 2016

Although brown adipose tissue is important with regard to energy balance, the molecular mechanism of brown adipocyte differentiation has not been extensively studied. Specifically, regulation factors at the level of protein modification are largely unknown. In this study, we examine the changes in the expression level of enzymes which are involved in protein lysine methylation during brown adipocyte differentiation. Several enzymes, in this case SUV420H2, PRDM9, MLL3 and JHDM1D, were found to be up-regulated. On the other hand, Set7/9 was significantly down-regulated. In the case of SUV420H2, the expression level increased sharply during brown adipocyte differentiation, whereas the expression of SUV420H2 was marginally enhanced during the white adipocyte differentiation. The knock-down of SUV420H2 caused the suppression of brown adipocyte differentiation, as compared to a scrambled control. These results suggest that SUV420H2, a methyltransferase, is involved in brown adipocyte differentiation, and that the methylation of protein lysine is important in brown adipocyte differentiation.

• Structural Engineering and Mechanics
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• v.33 no.5
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• pp.605-619
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• 2009

This paper presents the details of finite element (FE) modeling and analysis of an external prestressing technique to strengthen a prestressed concrete (PSC) end block. Various methods of external prestressing techniques have been discussed. In the proposed technique, transfer of external force is in shear mode on the end block creating a complex stress distribution. The proposed technique is useful when the ends of the PSC girders are not accessible. Finite element modeling issues have been outlined. Brief description about material nonlinearity including key aspects in modeling inelastic behaviour has been provided. Finite element (FE) modeling including material, loading has been explained in depth. FE analysis for linear and nonlinear static analysis has been conducted for varying external loadings. Various responses such as out-of-plane deformation and slip have been computed and compared with the corresponding experimental observations. From the study, it has been observed that the computed slope and slip of the steel bracket under external loading is in good agreement with the corresponding experimental observations.

• Journal of the Korean Chemical Society
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• v.56 no.4
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• pp.424-430
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• 2012

Densities, viscosities, refractive indices and speed of sounds of the binary mixtures of Acetophenone with Ethylchloroacetate were measured over the entire mole fractions at (303.15, 313.15 and 323.15) K. From these experimental results, excess molar volume $V^E$, viscosity deviation ${\Delta}{\eta}$, refractive index deviation ${\Delta}n_D$, deviations in speed of sound ${\Delta}u$, deviations in isentropic compressibility ${\Delta}k_s$ and excess intermolecular free length ${\Delta}L_f$ were calculated. The viscosity data have been correlated with the equations of Grunberg and Nissan, Hind et al., Tamura and Kurata, Katti and Chaudri, Sedgwick, Krishnan-Laddha and McAllister. The thermo physical properties under study were fit to the Jouyban-Acree model. The excess values were correlated using Redlich-Kister polynomial equation to obtain their coefficients and standard deviations. It was found that in all cases, the data obtained fitted with the values correlated by the corresponding models very well. The results are interpreted in terms of molecular interactions occurring in the solution.

• Bulletin of the Korean Chemical Society
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• v.31 no.9
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• pp.2656-2664
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• 2010

We have synthesized a series of push-pull porphyrins containing both donor and acceptor substituents at the mesopositions and have examined their spectral and biological properties. The push-pull porphyrins containing both strong donor $NH_2$ and acceptor $NO_2$ at meso-positions, in which donor group condensed with the ligand, (2,6-bis(4-methylpiperazine-1-yl-methyl)-4-formlyphenol (L) to form imine linkages with porphyrin. The Schiff base ligand 5-[4-(2,6-bis(4-methylpiperazine-1-yl-methyl)-4-iminomethylphenol)phenyl]-10,15,20-tris(4-nitrophenyl) porphyrin [$an_3$(TPP)L] can be synthesized from 2,6-bis(4-methylpiperazine-1-yl-methyl)-4-formylphenol (L) and 5-(4-aminophenyl)-10, 15,20-tris(4-nitrophenyl)porphyrin. The push-pull porphyrin [$an_3$(TPP)L] was metallated to get copper, nickel and zinc complexes. The spectral, electrochemical, antibacterial, antifungal and cytotoxicity properties of all the donor- acceptor push-pull porphyrins and their complexes were characterized and studied.

• Korean Journal of Environmental Biology
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• v.31 no.3
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• pp.189-191
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• 2013

Mycotoxins such as aflatoxin B1 (AFB1), ochratoxin A (OTA) and zearalenone (ZEA) are widespread contaminants of food and feedstuffs. It is very likely, that humans and animals are always exposed to mixtures of mycotoxins rather than to individual compounds. Therefore, risk assessments should consider mixture toxicity data. In the present study the combination of AFB1, OTA and ZEA was tested for genotoxicity in rat bone marrow and blood leukocytes after 15, 30 and 60 days treatment. The level of DNA damage was determined by the comet assay. The tail intensity and Olive tail moment in leukocytes and bone marrow cells were significantly higher than in controls. At the same time, the level of DNA damage in bone marrow cells was higher than in leukocytes. The data suggests that prolonged exposure to mycotoxins combination through food consumption can induce DNA damage contributing to the harmful effects in vivo.