• 제목/요약/키워드: Anion effects

검색결과 437건 처리시간 0.029초

Effects of dietary cation and anion difference on eating, ruminal function and plasma leptin in goats under tropical condition

  • Nguyen, Thiet;Chanpongsang, Somchai;Chaiyabutr, Narongsak;Thammacharoen, Sumpun
    • Asian-Australasian Journal of Animal Sciences
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    • 제33권6호
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    • pp.941-948
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    • 2020
  • Objective: This study was carried out to determine the effects of elevated dietary cation and anion difference (DCAD) on dry matter intake (DMI) and ruminal fermentation pattern in lactating dairy goats under tropical conditions. Methods: Ten dairy goats were divided into two groups of five animals each. The groups received diets at different DCAD levels, either a control diet (22.81 mEq/100 g dry matter [DM], DCAD-23) or a DCAD-39 diet (39.08 mEq/100 g DM, DCAD-39). After parturition, DMI and water intake were recorded daily. Ruminal fluid and urine were collected, and nutrient digestibility measurements were carried out at 8th weeks postpartum (PP-8). Blood samples were collected at PP-4 and PP-8 to measure plasma leptin. Results: Dry matter intake/body weight (DMI/BW) at PP-8 of the animals fed the DCAD-39 diet was significantly higher than those fed with DCAD-23 diet (p<0.05). Animals fed with DCAD-39 consumed more water than those fed DCAD-23 over 24 h, particularly at night (p<0.05). Ruminal pH, acetate concentration, and urinary allantoin excretion increased with the DCAD-39 diet, whereas ruminal butyrate concentration was lower with the DCAD-39 diet. On the other hand, other ruminal parameters, such as total volatile fatty acid concentration, propionate molar proportion and acetate/propionate average ratio, were not affected by increased DCAD supplementation. Apparent digestibility was improved by increased DCAD supplementation. Plasma leptin concentration was higher with DCAD supplementation. Conclusion: When feeding goats with DCAD-39 under tropical conditions, an increase in DMI was associated with improved apparent digestibility of nutrients, ruminal fermentation and microbial protein synthesis. An increase in plasma leptin concentration could not explain the effect of high DCAD on DMI.

노란콩 및 검정콩의 섭취가 흰쥐의 항산화 및 항노화 시스템에 미치는 영향 (Antioxidative and Antiaging Effects of Dietary Yellow and Black Soybean in Rats)

  • 류승희;문갑순
    • 한국식품영양과학회지
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    • 제32권4호
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    • pp.591-597
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    • 2003
  • 노란콩과 검정콩의 항산화효과를 생체 시스템에서 살펴보기 위해 S.D계 흰쥐에게 8주간 섭취시킨 후 지질 및 단백질 산화를 측정 한 결과 실험군은 대조군에 비해 산화를 억제하는 경향을 나타내었고 특히 검정콩의 경우 혈장에서 단백질 산화를 유의적으로 억제하였다. SOD 및 catalase 활성은 대조군과 실험군간에 유의적인 차이가 나타나지 않았고, GSH-px의 경우 대조군에 비해 노란콩 및 검정콩 섭취군에서 유의적으로 활성이 감소하였다. 간의 세포질에서 활성산소인 superoxide anion 함량을 측정한 결과 대조군에 비해 실험군 모두 superoxide anion 함량이 유의적으로 감소하였고 hydroxyl radical의 경우는 유의적인 차이는 없었으나 콩 섭취군에서 약간 감소하였다. 심장과 눈의 리포퓨신 함량을 측정한 결과 심장에서 대조군에 비해 실험군 모두 리포퓨신 축적을 유의적으로 억제하였고 눈에서도 대조군에 비해 검정콩 섭취군의 경우 유의적으로 리포퓨신 생성을 억제하였다. 전체적으로 생체 내에서 노란콩 및 검정콩의 항산화효과는 인정되었으며 종피 색의 차이는 크지 않은 것으로 나타났다.

조간탕가감방(調肝湯加減方)의 항산화활성(抗酸化活性) 및 항염증작용(抗炎症作用)에 대한 실험적(實驗的) 연구(硏究) (The Experimental Study on Anti-oxidant and Anti-inflammatory Effect of Jogantanggagambang(JGTG))

  • 변형국;유동열
    • 대한한방부인과학회지
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    • 제21권2호
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    • pp.76-96
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    • 2008
  • Purpose: This study was performed to evaluate anti-inflammatory effects of Jogantanggagambang(JGTG). Methods: In the study of anti-oxidant activities, JGTG was investigated by DPPH radical scavenger activity, superoxide dismutase activity and superoxide anion radical scavenger activity. In the study of anti-inflammatory effects, JGTG was investigated using cultured cells and murine models. As for the parameters of inflammation, levels of several inflammatory cytokines and chemical mediators which are known to be related to inflammation were measured in mouse lung fibroblast cells(mLFCs) and RAW264.7 cells. Results: 1. JGTG showed a safety in cytotoxicity and toxicity of liver. 2. JGTG effected scavenging activity on DPPH free radical, superoxide dismutase and superoxide anion radical. 3. JGTG in RAW 264.7 cell decreased IL-$1{\beta}$ mRNA expression, IL-6 mRNA expression, TNF-${\alpha}$ mRNA expression at 50, $100{\mu}g/m{\ell}$ and also decreased NOS-II mRNA expression at $100{\mu}g/m{\ell}$, and decreased COX-2 mRNA expression at 10, 50, $100{\mu}g/m{\ell}$. 4. JGTG in RAW 264.7 cell decreased significantly IL-$1{\beta}$, IL-6 and TNF-${\alpha}$ at 50, $100{\mu}g/m{\ell}$. 5. JGTG inhibited significantly IL-$1{\beta}$, IL-6 and TNF-${\alpha}$ production in serum of acute inflammation-induced mice. 6. JGTG decreased significantly IL-$1{\beta}$ mRNA production in spleen tissue. Conclusion: These results suggest that JGTG can be used for treating diverse female diseases caused by inflammation

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국내 유통 중인 식용식물 추출물의 항산화효과 (Anti-oxidative Activities of Commercial Edible Plant Extracts Distributed in Korea)

  • 김경범;유기환;박하얀;정종문
    • Applied Biological Chemistry
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    • 제49권4호
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    • pp.328-333
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    • 2006
  • 많은 식물 추출물들은 항산화 효능을 지니고 있으나 대량 생산 공정시 그들의 활성을 잃어버리는 경향이 있다. 따라서 본 본문에서는 대량 생산 공정을 거쳐 국내 유통 중인 43종의 식용식물 추출물을 대상으로 총 페놀 함량, DPPH 라디칼 포착 효능, 그리고 superoxide anion 라디칼 포착 효능을 측정하였다. 그 결과 개똥쑥(Artemisia annua, whole plant), 마태(Ilex paraguariensis leaf), 엉겅퀴(Silybum marianum, fruit 그리고 leaf), 유근피(Ulmus pumila, bark), 운지버섯(Coriolus versicolor, fruit) 그리고 울금(Curcuma longa, root 그리고 stem) 추출물은 70 mg/g 이상의 높은 페놀화합물을 함유하는 것으로 나타났다. DPPH 라디칼의 포착 효능에서 개똥쑥, 마테, 솔잎(Pinus densiflora, leaf), 엉겅퀴, 유근피, 그리고 울금 추출물의 $SC_{50}$ 값 측정 결과 각각 $53.96{\pm}0.81ppm,\;24.61{\pm}2.12ppm,\;35.96{\pm}1.11ppm,\;57.45{\pm}2.13ppm,\;55.25{\pm}1.65ppm$ 그리고 $12.99{\pm}1.67ppm$으로 나타났다(비타민 C의 $SC_{50}$값: $3.86{\pm}0.81ppm$). 또한 superoxide anion 라디칼 포착 효능에서는 개똥쑥, 계피(Cinnamomum zeylunicum, bark), 마테, 복분자(Rubus coreanus, fruit 그리고 leaf), 상엽(Morus alba, leaf), 솔잎, 엉겅퀴, 유근피, 운지버섯, 울금, 자소엽(Perilla frutescens var. acuta, leaf) 그리고 히비스커스(Hibiscus sabdariffa, leaf) 그리고 flower) 추출물의 $SC_{50}$ 값 측정 결과 각각 $53.21{\pm}1.83ppm,\;50.12{\pm}2.12ppm,\;5.59{\pm}0.84ppm,\;41.60{\pm}8.93ppm,\;20.19{\pm}0.97ppm,\;15.19{\pm}1.66ppm,\;21.20{\pm}1.88ppm,\;15.71{\pm}0.91ppm,\;55.48{\pm}2.42ppm,\;52.12{\pm}2.44ppm,\;23.80{\pm}1.98ppm$ 그리고 $11.14{\pm}0.51ppm$인 것으로 나타났다(비타민 C의 $SC_{50}$ 값:$9.61{\pm}0.93ppm$). 특히 마테 추출물과 솔잎 추출물은 총 페놀 함량이 높으면서 DPPH 라디칼과 superoxide anion 라디칼을 동시에 효율적으로 포착하는 효능을 지니고 있는 것으로 나타났다. 결론적으로 마테와 솔잎의 상업적인 추출물은 기능성 항산화제로서 유용한 소재로 사용 가능 할 것으로 사료된다.

팔면체형 철 (Ⅱ) Vicinal-디옥심 착물의 물리적 성질 (Physical Properties of Octahedral Iron (Ⅱ) Complexes of Vicinal-Dioximes)

  • 진종식
    • 대한화학회지
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    • 제24권5호
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    • pp.380-392
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    • 1980
  • 6배위, 작은 스핀 철(Ⅱ)착화합물, [Fe$(DH)_2B_2$]과 [Fe(D$H_2$B(CO)]($(DH)_2$=$(CHDH)_2$-(bis(1,2-cyclohexadinedioximato)(bivalent anion),$(DPGH)_2$(bis(diphenylglyoximato) bivalent anion), $(F{\alpha}DH)_2(bis(furil-{\alpaha}$-dioximato) bivalent anion), B = neutral monodentate nitrogen base)을 합성하여 이들의 물리적 성질을 적도 방향의 리간드, $(DH)_2$에 관하여 조사하였다. 적외선 스펙트럼 분석결과, [Fe$(DH)_2B(CO)] 중에서 {\pi}$-전자받게 리간드인 CO의 신축진동수 크기의 순서는 $(F{\alpha}DH)_2$ > $(DPGH)_2$ > $(CHDH)_2 화합물의 순서이고 [Fe$(DH)_2(NH_3)_2$]중에서 ${\pi}$-전자받게 성질이 없는 $NH_3$의 신축진동수 크기의 순서는 그 반대인 $(CHDH)_2$ > $(DPGH)_2 > $(F{\alpha}DH)_2$ 화합물임을 관찰하였다. 이상의 결과와 철-질소(옥심) 및 철-질소(B)의 신축진동수 데이타로부터 다음을 알았다. 즉 $(CHDH)_2$중의 질소원자들은 $(DPGH)_2$$(F{\alpha}DH)_2$ 중의 질소원자들보다 염기도는 크지만 ${\pi}$-전자받게의 경향은 적다. 상기 착물들의 전자스펙트럼을 조사한 결과 $(DH)_2의 염기도가 증가함에 따라 철로부터 $(DH)_2$로 일어나는 전하이동띠의 에너지가 증가함을 알았다.

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Research in the antioxidant of Phellinus linteus mycelia

  • Nakamura, Tomoyuki;Akiyama, Yukihito;Matsugo, Seiichi;Shibata, Keiji;Kawagishi, Hirokazu
    • Journal of Photoscience
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    • 제9권2호
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    • pp.421-423
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    • 2002
  • Phellinus linteus mycelia have many pharmacological effects, although their pharmacological efficacy principles have not been known yet. In the course of screening for biological activity of the extracts of Phellinus linteus mycelia, we found strong antioxidative activity in some fraction of water-insoluble. Therefore, we tried to isolate the active principle(s) from the extract. The isolation of the active compound was guided by superoxide anion radical scavenging activity. As a result, caffeic acid was isolated as an active compound. The IC$\_$50/ of the compound was 3.05 $\mu$g/ml (16.9$\mu$M).

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Effect of L-theanine on non-specific immunoparameters in catfish (Silurus asortus)

  • Heo, Gang-Joon;Shin, Gee-Wook
    • 한국동물위생학회지
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    • 제35권4호
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    • pp.347-350
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    • 2012
  • L-theanine was examined for its effects on the generation of superoxide anion, lysozyme and anti-protease in the plasma of catfish (Silurus asotus) by a single intraperitoneal injection with five different concentrations (0, 3, 6, 9 and 12 mg/kg). When compared with the mock-injected group (0 mg/kg), both groups injected with 6 and 9 mg/kg were significantly enhanced in levels of superoxide anion in leukocytes, lysozyme and anti-protease in plasma. Based on the results, L-theanine is thought to function as an immunostimulant and/or immunomodulator on non-specific immune responses in catfish.