DOI QR코드

DOI QR Code

Effect of L-theanine on non-specific immunoparameters in catfish (Silurus asortus)

  • Heo, Gang-Joon (College of Veterinary Medicine, Chungbuk National University) ;
  • Shin, Gee-Wook (Bio-Safety Research Institute and College of Veterinary Medicine, Chonbuk National University)
  • Received : 2012.09.27
  • Accepted : 2012.11.09
  • Published : 2012.12.30

Abstract

L-theanine was examined for its effects on the generation of superoxide anion, lysozyme and anti-protease in the plasma of catfish (Silurus asotus) by a single intraperitoneal injection with five different concentrations (0, 3, 6, 9 and 12 mg/kg). When compared with the mock-injected group (0 mg/kg), both groups injected with 6 and 9 mg/kg were significantly enhanced in levels of superoxide anion in leukocytes, lysozyme and anti-protease in plasma. Based on the results, L-theanine is thought to function as an immunostimulant and/or immunomodulator on non-specific immune responses in catfish.

Keywords

References

  1. Babu PV, Sabitha KE, Shyamaladevi CS. 2006. Therapeutic effect of green tea extract on oxidative stress in aorta and heart of streptozotocin diabetic rats. Chem Biol Interact 162: 114-120. https://doi.org/10.1016/j.cbi.2006.04.009
  2. Bowden TJ, Butler R, Bricknell IR, Ellis AE. 1997. Serum trypsin- inhibitory activity in five species of farmed fish. Fish Shellfish Immunol 7: 377-385. https://doi.org/10.1006/fsim.1997.0092
  3. Bukowski JF, Percival SS. 2008. L-theanine intervention enhances human gammadelta T lymphocyte function. Nutr Rev 66: 96-102. https://doi.org/10.1111/j.1753-4887.2007.00013.x
  4. Cho HS, Kim S, Lee SY, Park JA, Kim SJ, Chun HS. 2008. Protective effect of the green tea component, L-theanine on environmental toxins-induced neuronal cell death. Neurotoxicology 29: 656-662. https://doi.org/10.1016/j.neuro.2008.03.004
  5. Dautremepuits C, Paris-Palacios S, Betoulle S, Vernet G. 2004. Modulation in hepatic and head kidney parameters of carp (Cyprinus carpio L.) induced by copper and chitosan. Comp Biochem Physiol Toxicol Pharmacol 137: 325-333. https://doi.org/10.1016/j.cca.2004.03.005
  6. Ellis AE. 1999. Immunity to bacteria in fish. Fish Shellfish Immunol 9: 291-308. https://doi.org/10.1006/fsim.1998.0192
  7. Esteban MA, Mulero V, Cuesta A, Ortuño J, Meseguer J. 2000. Effects of injecting chitin particles on the innate immune response of gilthead seabream (Sparus aurata L.). Fish Shellfish Immunol 10: 543-554. https://doi.org/10.1006/fsim.2000.0271
  8. Heo G, Shin G. 2011. Effect of chitosan oligosaccharide on non-specific immune parameters in catfish (Silurus asotus). Philipp J Vet Med 48: 22-26.
  9. Juneja LR, Chu DC, Okubo T, Nagato Y, Yokogoshi H. 1999. L-theanine - a unique amino acid of green tea and its relaxation effect in humans. Trends Food Sci Tech 10: 199-204. https://doi.org/10.1016/S0924-2244(99)00044-8
  10. Kajita Y, Sakai M, Atsuta S, Kobayashi M. 1992. Immunopotentiation activity of freund complete adjuvant in rainbow- trout Oncorhynchus mykiss. Bull Jap Soc Sci Fish 58: 433-437. https://doi.org/10.2331/suisan.58.433
  11. Kimura K, Ozeki M, Juneja LR, Ohira H. 2007. L-Theanine reduces psychological and physiological stress responses. Biol Psychol 74: 39-45. https://doi.org/10.1016/j.biopsycho.2006.06.006
  12. Kono M, Matsui T, Shimizu C. 1987. Effect of chitin, chitosan, and cellulose as diet supplements on the growth of cultured fish. Bull Jap Soc Sci Fish 53: 125-129. https://doi.org/10.2331/suisan.53.125
  13. Kurihara S, Shibahara S, Arisaka H, Akiyama Y. 2007. Enhancement of antigen-specific immunoglobulin G production in mice by co-administration of L-cystine and L-theanine. J Vet Med Sci 69: 1263-1270. https://doi.org/10.1292/jvms.69.1263
  14. Naito Y, Yoshikawa T. 2009. Green tea and heart health. J Cardiovasc Pharmacol 54: 385-390. https://doi.org/10.1097/FJC.0b013e3181b6e7a1
  15. Nathan PJ, Lu K, Gray M, Oliver C. 2006. The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent. J Herb Pharmacother 6: 21-30.
  16. Park SK, Jung IC, Lee WK, Lee YS, Park HK, Go HJ, Kim K, Lim NK, Hong JT, Ly SY, Rho SS. 2011. A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study. J Med food 14: 334-343. https://doi.org/10.1089/jmf.2009.1374
  17. Verlhac V, Obach A, Gabaudan J, Schuep W, Hole R. 1998. Immunomodulation by dietary vitamin C and glucan in rainbow trout (Oncorhynchus mykiss). Fish Shellfish Immunol 8: 409-424. https://doi.org/10.1006/fsim.1998.0148
  18. Vuong QV, Bowyer MC, Roach PD. 2011. L-Theanine: properties, synthesis and isolation from tea. J Sci Food Agric 91: 1931-1939. https://doi.org/10.1002/jsfa.4373