• Title/Summary/Keyword: Animal Training

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An Application of Tucker Decomposition for Detecting Epilepsy EEG signals

  • Thieu, Thao Nguyen;Yang, Hyung-Jeong
    • Journal of Multimedia Information System
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    • v.2 no.2
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    • pp.215-222
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    • 2015
  • Epileptic Seizure is a popular brain disease in the world. It affects the nervous system and the activities of brain function that make a person who has seizure signs cannot control and predict his actions. Based on the Electroencephalography (EEG) signals which are recorded from human or animal brains, the scientists use many methods to detect and recognize the abnormal activities of brain. Tucker model is investigated to solve this problem. Tucker decomposition is known as a higher-order form of Singular Value Decomposition (SVD), a well-known algorithm for decomposing a matric. It is widely used to extract good features of a tensor. After decomposing, the result of Tucker decomposition is a core tensor and some factor matrices along each mode. This core tensor contains a number of the best information of original data. In this paper, we used Tucker decomposition as a way to obtain good features. Training data is primarily applied into the core tensor and the remained matrices will be combined with the test data to build the Tucker base that is used for testing. Using core tensor makes the process simpler and obtains higher accuracies.

Dissemination of Advanced Mouse Resources and Technologies at RIKEN BioResource Center

  • Yoshiki, Atsushi
    • Interdisciplinary Bio Central
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    • v.2 no.4
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    • pp.15.1-15.5
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    • 2010
  • RIKEN BioResource Center (BRC) has collected, preserved, conducted quality control of, and distributed mouse resources since 2002 as the core facility of the National BioResource Project by the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan. Our mouse resources include over 5,000 strains such as humanized disease models, fluorescent reporters, and knockout mice. We have developed novel mouse strains such as tissue-specific Cre-drivers and optogenetic strains that are in high demand by the research community. We have removed all our specified pathogens from the deposited mice and used our quality control tests to examine their genetic modifications and backgrounds. RIKEN BRC is a founding member of the Federation of International Mouse Resources and the Asian Mouse Mutagenesis and Resource Association, and provides mouse resources to the one-stop International Mouse Strain Resource database. RIKEN BRC also participates in the International Gene Trap Consortium, having registered 713 gene-trap clones and their sequences in a public library, and is an advisory member of the CREATE (Coordination of resources for conditional expression of mutated mouse alleles) consortium which represents major European and international mouse database holders for the integration and dissemination of Cre-driver strains. RIKEN BRC provides training courses in the use of advanced technologies for the quality control and cryopreservation of mouse strains to promote the effective use of mouse resources worldwide.

Challenges in the Toxicological(Mutagenic and Teratogenic)/Environmental methods under the GLP system

  • Andrson, D.
    • Proceedings of the Korea Society of Environmental Toocicology Conference
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    • 2002.10a
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    • pp.107-116
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    • 2002
  • GLP regulations were initially “promulgated to address assuring the validity of data in the wake of investigations by EPA and FDA during the mid -1970's which revealed that some studies submitted to the agencies had not been conducted in accordance with acceptable laboratory practices.” [1] In the early 1970s, results of an investigation by the FDA in about 40 laboratories revealed many cases of badly managed studies, poor training of personnel and some cases of deliberate fraud. The general findings were that there were poorly trained study directors and study personnel, poorly designed protocols, protocols not followed, procedures not conducted as described, raw data badly collected, data not correctly identified, data without traceability, data not verified and approved by responsible persons, lack of standardised procedures, poor animal husbandry, inadequate characterisation of test items and test systems, inadequate resources, equipment poorly calibrated or otherwise qualified, reports not sufficiently verified, not an accurate account of the actual study, not a proper reflection of raw data and inadequate archiving of data. These problems are not just past history, since they resurface time and time again, even in quite recent times as the experience of GLP inspectors shows [1]. The GLPs specify minimum practices and procedures in order to ensure the quality and integrity of data submitted in accordance with a regulatory requirement

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Therapeutic Approach for Stroke Patients based on Central Pattern Generator (중추유형발생기에 근거한 뇌졸중 환자의 치료적 접근)

  • Kim Joong-Hwi;Kim Chung-Sun
    • The Journal of Korean Physical Therapy
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    • v.14 no.4
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    • pp.131-146
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    • 2002
  • In the last years, it has become possible to regain some locomotor activity in patients with incomplete spinal cord injury (SCI) through intense training on a treadmill. The ideas behind this approach owe much to insights derived from animal studies. Many studies showed that cats with complete spinal cord transection(spinalized animals) can recover locomotor function. These observations were at the basis of the concept of the central pattern generator located at spinal level. The neural system responsible for the locomotor restoration in both cats and humans is thought to be located at spinal level and is referred to as the central pattern generator(CPG). The evidence for such a spinal CPG in human is emphasis on some recent developments which support the view that there is a human spinal CPG for locomotion. An important element in afferent inputs for both spinal injured cats and humans is the provision of adequate sensory input related locomotor, which can possibly activate and/or regulate the spinal locomotor circuitry This review article deals with the afferent control of the central pattern generator. Furthermore, the application of adequate afferent inputs related locomotor for stroke patients will be able to facilitate locomotion ability, which is automatic, cyclic, rhythmic. These insights can possibly contribute to a better therapeutic approach for the rehabilitation of gait in patients with stroke.

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Study on the Support Policy for Recycling Food Wastes into Feed & Compost (음식물류 폐기물의 사료화 및 퇴비화 등 자원화 지원정책에 관한 연구)

  • Ahn Sang-Sun
    • Journal of Soil and Groundwater Environment
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    • v.10 no.3
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    • pp.52-63
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    • 2005
  • Korea has recently implemented two m메or policies on organic wastes, including food wastes. One is the Volume-Based waste Fee System (VBWFS). which went effect nationwide in January 1995, and the other is a ban on the landfill of organic wastes, such as food wastes. organic sludge, and animal manure, in accordance with the Waste Management Act. These two policies have brought about remarkable positive effects, including the reduction of organic wastes at source, and the development of technology for recycling food wastes into feed and compost. However, they have caused obstacles to carry out the policy on food wastes, in areas of legal and technological infrastructures for recycling. Therefore, this study intends to find problems of policies for recycling food wastes, and to suggest ways to resolve them.

Use of Human Placentas for Practice of Microvascular Surgery (미세수술 술기 습득을 위한 태반의 사용)

  • Kang, Min-Gu;Yoon, Sang-Yup;Chang, Hak
    • Archives of Reconstructive Microsurgery
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    • v.16 no.2
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    • pp.53-56
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    • 2007
  • Purpose: Microsurgical exercise has been performed with rat femoral vessels. But, it needs animal laboratory, anesthesia and its keeping facilities. Materials and Methods: Ten human placentas were studied for suitability in a microvascular exercise. The size and useful length of vessels were measured, and various microvascular anastomoses were performed. Result: The human placenta has many vessels traversing its fetal surface. A variety of sizes are available down to vessels of diameter 1 mm and up to vessels of diameter 6.5 mm (1.0

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Environmental Factors Affecting Establishment and Expansion of the Invasive Alien Species of Tree of Heaven (Ailanthus altissima) in Seoripool Park, Seoul

  • Lee, Han-Wool;Lee, Chang-Seok
    • Animal cells and systems
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    • v.10 no.1
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    • pp.27-40
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    • 2006
  • Tree of heaven (Ailanthus altissima Swingle) as an invasive alien plant, appeared usually in the disturbed locations such as road-side, incised slope, and trampling path-side. They appeared abundantly in the trampling pathside but they did not appear or were rare in the interior of forest. Density and importance value of tree of heaven were proportionate to the relative light intensity measured according to distance from the trampling path toward forest interior and closely related to the breadth of trampling path as well. They were associated with annual, other exotic species or ruderal plants well. Distributional pattern of mature trees of them in the study area and its surrounding environments implied that they were introduced intentionally. Size class distribution of them showed that they are in expansion and artificial interferences such as, installing physical training space and developing hiking course functioned as trigger factors in their invasion and expansion. The results support the facts known generally in relation to invasion and expansion of the invasive alien plants. In this viewpoint, we suggest a management plan that applies ecological restoration principles to address ecosystems infected with tree of heaven by restoring the integral feature of the degraded nature and conserving the remained nature more thoroughly.

Virucidal efficacy of a disinfectant solution composed of n-alkyl-dimethyl-benzyl-ammonium chloride against porcine epidemic diarrhea virus

  • Cha, Chun-Nam;Yu, Eun-Ah;Yoo, Chang-Yeul;Cho, Ki-Yung;Lee, Soo-Ung;Kim, Suk;Lee, Hu-Jang
    • Korean Journal of Veterinary Service
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    • v.37 no.2
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    • pp.105-110
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    • 2014
  • Porcine epidemic diarrhea virus (PEDV) is the causative agent of porcine epidemic diarrhea (PED) and causes a considerable economic loss in swine industry. In this study, the virucidal efficacy of the disinfectant composed to n-alkyl-dimethyl-benzyl-ammonium chloride (n-ADBAC) was investigated against PEDV. A virucidal efficacy was determined with the viability of PEDV contacted with the disinfectant in Vero cells. The disinfectant and PEDV were reacted on the hard water (HW) or organic matter suspension (OM) condition. On HW condition, PEDV was inactivated with 50 fold dilutions of the disinfectant. When the antiviral effect on OM condition was evaluated, the antiviral activity of the disinfectant showed on 10 fold dilutions against PEDV. As the disinfectant possesses the virucidal efficacy against PEDV, the disinfectant solution can be used to limit the spread of animal viral diseases.

In vitro Estimation of Cardiac Output for the TAH using an Adaptive Fuzzy Identifier

  • Choi, W.W.;Jo, Y.H.;Ahn, J.M.;Park, S.K.;Choi, J.S.;Om, K.S.;Lee, J.J.;Choi, J.H.;Kim, H.C.;Min, B.G.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.11
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    • pp.263-267
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    • 1996
  • An estimation algorithm based on training of fuzzy logic system using back-propagation is proposed, in this paper, for determining cardiac output in the TAH. The proposed estimation utilizes only a motor current waveform generated from the moving actuator of the electromechanical TAH without using any extra transducers as an information source for estimation. In in vitro tests, the resultant estimation performance was acceptable to alppy the proposed algorithm to animal experiments and further clinical applications.

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Dexamethasone reduces infectious bursal disease mortality in chickens

  • Shin, Seung Yub;Han, Tae Hee;Kwon, Hyuk Joon;Kim, Sun Joong;Ryu, Pan Dong
    • Journal of Veterinary Science
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    • v.22 no.3
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    • pp.33.1-33.6
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    • 2021
  • Very virulent infectious bursal disease virus (vvIBDV) causes high mortality in chickens but measures to reduce the mortality have not been explored. Chickens (8-9 weeks) were treated with 3 agents before and during vvIBDV inoculation. Dexamethasone treatment reduced the mortality of infected chickens (40.7% vs. 3.7%; p < 0.001), but treatment with aspirin or vitamin E plus selenium did not affect the mortality. The bursa of Fabricius appeared to have shrunk in both dead and surviving chickens (p < 0.01). The results indicate that dexamethasone can reduce mortality in vvIBDV-infected chickens and may provide therapeutic clues for saving individual birds infected by the virus.