• Korean Journal of Fisheries and Aquatic Sciences
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• v.52 no.4
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• pp.382-388
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• 2019

Streptococcosis caused by Streptococcus parauberis is a very important disease in farmed olive flounder Paralichthys olivaceus. For most fish pathogens, including S. parauberis, there are no analytical criteria to distinguish antibioticsusceptible strains from antibiotic-resistant strains. In this study, epidemiological cut-off ($CO_{WT}$) values were generated to classify 75 strains of S. parauberis isolated from 1999 to 2018 as wild type (WT) and non-wild type (NWT) using disc diffusion data and normalized resistance interpretation (NRI) analysis. The susceptibility of the isolates to 16 antibiotics was evaluated using CLSI guideline M42-A. The wild-type cut-off values for amoxicillin, erythromycin, oxytetracycline, and florfenicol for S. parauberis were ${\geq}35$, 31, 28, and 27 mm, respectively. The NWT ratios of S. parauberis strains to treatment with GEN, FFC, ENR, SXT, EFT, VAN, and CHL were 17% or less, indicating that these antibiotics may be used to treat streptococcosis caused by S. parauberis. For recent S. parauberis isolates, the NWT ratios for AMX, ERY, OTC and FFC are much higher than for strains isolated from 1999-2007. The $CO_{WT}$ data from this study will assist aquatic animal disease professionals in prescribing appropriate antibiotics for the treatment of streptococcosis caused by S. parauberis, which will help reduce the misuse and abuse of antibiotics in the aquaculture sector.

• Journal of Food Hygiene and Safety
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• v.34 no.1
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• pp.52-57
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• 2019

Method development and validation of decursin for the standardization of Angelica gigas Nakai as a functional ingredient and health food were accomplished. The quantitative determination method of decursin as a marker compound of aerial parts of Angelica gigas Nakai extract (AAGE) was optimized by HPLC analysis using a C18 column ($3{\times}150mm$, $3{\mu}m$) with 0.1% TFA in water and acetonitrile as the mobile phase at a flow rate of 0.5 mL/min and detection wavelength of 330 nm. The HPLC/PDA method was applied successfully to quantification of the marker compound in AAGE after validation of the method with linearity, accuracy, and precision. The method showed high linearity in the calibration curve at a coefficient of correlation ($R^2$) of 0.9994 and the limit of detection and limit of quantitation were $0.011{\mu}g/mL$ and $0.033{\mu}g/mL$, respectively. Relative standard deviation (RSD) values of data from intra- and inter-day precision were less than 1.10% and 1.13%, respectively. Recovery of decursin at 0.5, 1, 5 and $10{\mu}g/mL$ were 92.38 ~ 104.11%. These results suggest that the developed HPLC method is very useful for the determination of marker compound in AAGE to develop a health functional material.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.38 no.6
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• pp.783-791
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• 2018

The biased estimation of low density rainfall network and radar rainfall has limited application to extreme rainfall in a small area. To improve this, more rainfall information needs to be produced. In this study, we analyzed the applicability of the vehicle rainfall sensor developed and used recently. The developed rainfall sensor was attached to the vehicle to observe the rainfall according to the movement of the vehicle. The analytical method used time series and average rainfall values for observations of rainfall sensors and nearby rainfall stations. The results show that the trend of observed values according to rainfall events shows a certain pattern. It is analyzed that it is caused by various causes such as the difference between the observation position of the rainfall sensor and the nearby rainfall station, the moving speed of the vehicle, and the rainfall observation method. This result shows the possibility of rainfall observation using a rainfall sensor for a vehicle, and it is possible to observe rainfall more precisely through experiments and improvement of rainfall sensors in various conditions in the future.

• Korean Journal of Clinical Pharmacy
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• v.29 no.1
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• pp.45-55
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• 2019

Background: Although the importance of pharmaceutical care service has been growing to meet the needs of customers with the improvement of clinical and humanistic outcomes, there was not a systematic strategy to promote research in Korea. The aim of this study was to suggest the core agendas for pharmaceutical care services research and development (R&D) considering priorities. Methods: Based on desk researches, we developed R&D agendas for the needs of improving pharmaceutical care services in the area of institution, community, and public health. To determine the priority of agendas in developing pharmaceutical care service, analytic hierarchy process (AHP) analysis was performed by the 14 experts. Criteria and subcriteria were assessed for significance by pairwise comparisons. Then, agendas were evaluated for importance according to each subcriteria, and rank ordered considering the weight calculated by multiplying the importance scores of the criteria and the subcriteria. Results: We derived 25 agendas including 13 for institutional pharmaceutical care service, 8 for community pharmaceutical care service, and 4 for public-health related pharmaceutical care service. AHP model was constructed based on 4 criteria and 8 subcriteria by a hierarchical structure. From the AHP survey, the 'Development of pharmaceutical care service for metabolic and chronic disease' agenda accounted for the highest priority. Conclusion: We have developed the R&D agendas of the pharmaceutical care service which should be promoted. The results should be utilized by the government to nationally support the development of the standards and relevant regulations related to pharmaceutical care services in Korea.

• Korean Journal of Clinical Laboratory Science
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• v.50 no.4
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• pp.525-534
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• 2018

This study evaluated the various qualifications that can be linked to employment similar to the medical laboratory technology major. The qualifications for employment outside the medical laboratory technology major are industrial health instructor, doping control officer, audiologist, sign language interpreter, health education specialist, claim adjuster, Korea life underwriter, administrative manager, hospital administrator, insurance review manager, and hospital coordinator. The qualifications for employment similar to the medical laboratory technology major include the clinical research coordinator, clinical research associate, anatomist, analytical chemistry analysts, hazardous materials industry engineers, biotechnologist, biosafety managers, biotechnology technicians, medical device quality officers, animal care nurse, industrial engineer hazardous material, bioprocess engineer, biosafety officer, certified technology consultant, director of medical device quality control, laboratory animal technician, animal nursing technician, and cruise medical manager. Therefore, it is necessary to conduct a social analysis survey of the various qualifications currently held by medical technologists. In addition, it will be necessary to investigate the current status of medical technologists working in other fields. In the future, medical technologists should expand the scope of their work through efforts to strengthen their individual work capacity, share cases, and strengthen their expertise.

• Journal of the Korean GEO-environmental Society
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• v.19 no.12
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• pp.59-64
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• 2018

The damages to the reinforced earth retaining wall are divided into the front wall, foundation, drainage and upper slope. Damage of reinforced earth retaining wall is mainly caused by damage caused by drainage problem in the field. Recently, damage caused by snow removal materials have been occurred. Recently, the amount of snow removal materials used in winter is increasing due to abnormal weather. This chlorides degrades the concrete structure, where the reinforced earth retaining wall was no exception. There has recently been a case in which the front wall of the reinforced earth retaining wall deteriorates due to the chlorides introduced into the back filling portion through the drainage passage. Therefore, in this study, the cause of damages of reinforced earth retaining wall constructed in bridge abutment was analyzed, and an analytical study was conducted on the countermeasure. As a result, it was found that chlorides, which was introduced through the drainage system in the expansion joint of the bridge shift part or the upper structure, is infiltrated into the back part of the reinforced earth retaining wall and damaged. Therefore, it is suggested to improve the drainage system and restored the stiffness of the front wall.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.9
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• pp.481-487
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• 2019

Additive manufacturing is a state-of-the-art manufacturing process technology in which three-dimensional structures are fabricated by laminating two-dimensional sections of a structure using various materials such as plastic, ceramics, and metals. The additive manufacturing technology has the advantage of high design freedom, while the surface property (roughness) of the finished product varies depending on the process conditions, which necessitates performing a post-process after the products are manufactured. In this study, the surface roughness of a structure made of polyamide 12, which was manufactured by SLS (Selective Laser Sintering) and MJF (Multi Jet Fusion) process was compared. The processing condition was classified by the building orientation of structure as 0, 45, and 90 degrees, which is the angle between the analytical surface and the horizontal plane of the fabrication platform. Structures with a hole of various diameters ranging from 1mm to 10mm were manufactured and the hole characteristics (ratio of hole depth to diameter) and results of the specimens were compared. As a result of the surface characteristics analysis, the surface roughness value of the specimens manufactured with a building orientation of $45^{\circ}$ was the highest in both technologies. In the case of the through-hole structure fabrication, the shape was maintained with 5mm and 10mm diameter holes regardless of the building orientation, although the hole forming was difficult for the smaller holes.

• The Journal of Bigdata
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• v.3 no.2
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• pp.19-33
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• 2018

Owing to the increase of FTA, food trade, and versatile preferences of consumers, food import has increased at tremendous rate every year. While the inspection check of imported food accounts for about 20% of the total food import, the budget and manpower necessary for the government's import inspection control is reaching its limit. The sudden import food accidents can cause enormous social and economic losses. Therefore, predictive system to forecast the compliance of food import with its preemptive measures will greatly improve the efficiency and effectiveness of import safety control management. There has already been a huge data accumulated from the past. The processed foods account for 75% of the total food import in the import food sector. The analysis of big data and the application of analytical techniques are also used to extract meaningful information from a large amount of data. Unfortunately, not many studies have been done regarding analyzing the import food and its implication with understanding the big data of food import. In this context, this study applied a variety of classification algorithms in the field of machine learning and suggested a data preprocessing method through the generation of new derivative variables to improve the accuracy of the model. In addition, the present study compared the performance of the predictive classification algorithms with the general base classifier. The Gaussian Naïve Bayes prediction model among various base classifiers showed the best performance to detect and predict the nonconformity of imported food. In the future, it is expected that the application of the abnormality detection model using the Gaussian Naïve Bayes. The predictive model will reduce the burdens of the inspection of import food and increase the non-conformity rate, which will have a great effect on the efficiency of the food import safety control and the speed of import customs clearance.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.7
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• pp.203-210
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• 2019

A recent earthquake on the Korean Peninsula caused much damage to masonry buildings, and research on performance evaluation has been underway. A masonry building is generally constructed using wet construction and is affected by temperature, which reduces the efficiency of the construction. In this study, we propose a dry construction technique for assembling concrete blocks without using mortar and evaluated its performance through experimental and analytical research. To evaluate the performance, experiments were carried out for the prismatic compressive strength, direct terminal strength, and diagonal tensile strength of the dry construction wall. The adequacy of the cross section shape was also reviewed through FEM analysis. The results show that the compressive strength and diagonal tensile strength could exert a certain intensity or higher. Furthermore, the H-type module of a key block acted as a shear key for the entire concrete block, which resulted in excellent shear strength performance. In addition, the shape and thickness of the main block have a major effect on the strength performance of each block. Therefore, an optimal shape and the proposed dry construction method could be applied to replace the wet method by studying the construction or seismic performance of the proposed method.

• Journal of The Korean Association For Science Education
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• v.39 no.2
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• pp.295-305
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• 2019

In previous study, visual representation competence taxonomy (VRC-T), which is composed of two dimensions, was developed for the purpose of promoting effective visual representation use and research in science education. In this study, elementary school students' visual representation competence for shadow phenomenon was investigated using VRC-T. In terms of visual representation competence, 'interpretation' was the highest score, followed by 'construction' and 'integration'. It also showed that students' visual representation competence was not high even after learning shadow-related units in the regular curriculum. On the other hand, text-based scientific knowledge was not correlated with all categories of visual representation competence. This indicates that there is a need to emphasize visual representation more in science class. Finally, hierarchical relationship among cognitive processes of VRC-T was explored according to ordering theory. If the tolerance level is somewhat loosened, a linear hierarchical relationship was found between the six cognitive processes. This suggests that VRC-T is an analytical framework that can be useful when designing assessment tools, tasks, and science class activities to enhance visual representation competence.